DEAD-box helicase-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Download

Quick info

Protein:

Gene product:

DEAD-box helicase-like protein

Species:

Leishmania infantum

UniProt:

A4I335_LEIIN

TriTrypDb:

LINF_270005400

Length:

140

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I335

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I335

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	2
GO:0004386	helicase activity	2	2
GO:0140640	catalytic activity, acting on a nucleic acid	2	2
GO:0140657	ATP-dependent activity	1	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	77	81	PF00656	0.289
CLV_C14_Caspase3-7	91	95	PF00656	0.281
CLV_NRD_NRD_1	112	114	PF00675	0.436
CLV_NRD_NRD_1	36	38	PF00675	0.354
CLV_NRD_NRD_1	5	7	PF00675	0.381
CLV_PCSK_KEX2_1	112	114	PF00082	0.436
CLV_PCSK_KEX2_1	15	17	PF00082	0.340
CLV_PCSK_KEX2_1	36	38	PF00082	0.354
CLV_PCSK_PC1ET2_1	15	17	PF00082	0.340
CLV_PCSK_SKI1_1	118	122	PF00082	0.431
CLV_PCSK_SKI1_1	15	19	PF00082	0.332
DEG_Nend_UBRbox_2	1	3	PF02207	0.392
DOC_MAPK_gen_1	36	42	PF00069	0.342
DOC_MAPK_gen_1	65	74	PF00069	0.279
DOC_MAPK_MEF2A_6	56	64	PF00069	0.310
DOC_MAPK_MEF2A_6	65	74	PF00069	0.279
DOC_PP1_RVXF_1	83	90	PF00149	0.295
DOC_PP4_FxxP_1	49	52	PF00568	0.342
DOC_USP7_MATH_1	126	130	PF00917	0.402
DOC_WW_Pin1_4	105	110	PF00397	0.340
LIG_14-3-3_CanoR_1	112	116	PF00244	0.441
LIG_14-3-3_CanoR_1	124	129	PF00244	0.414
LIG_14-3-3_CanoR_1	29	35	PF00244	0.298
LIG_14-3-3_CanoR_1	67	71	PF00244	0.276
LIG_BRCT_BRCA1_1	94	98	PF00533	0.277
LIG_FHA_1	22	28	PF00498	0.294
LIG_FHA_1	46	52	PF00498	0.366
LIG_FHA_1	94	100	PF00498	0.274
LIG_FHA_2	20	26	PF00498	0.309
LIG_LIR_Apic_2	47	52	PF02991	0.359
LIG_LIR_Gen_1	95	106	PF02991	0.286
LIG_LIR_Nem_3	95	101	PF02991	0.273
LIG_NRBOX	67	73	PF00104	0.274
LIG_SH2_PTP2	59	62	PF00017	0.302
LIG_SH2_STAT5	100	103	PF00017	0.286
LIG_SH2_STAT5	59	62	PF00017	0.302
LIG_SH3_3	57	63	PF00018	0.308
LIG_WRC_WIRS_1	71	76	PF05994	0.269
MOD_CDK_SPxxK_3	105	112	PF00069	0.355
MOD_CK1_1	127	133	PF00069	0.393
MOD_CK1_1	50	56	PF00069	0.331
MOD_CK2_1	19	25	PF00069	0.317
MOD_GlcNHglycan	19	22	PF01048	0.328
MOD_GSK3_1	101	108	PF00069	0.307
MOD_GSK3_1	120	127	PF00069	0.429
MOD_GSK3_1	17	24	PF00069	0.318
MOD_GSK3_1	47	54	PF00069	0.354
MOD_GSK3_1	66	73	PF00069	0.274
MOD_GSK3_1	88	95	PF00069	0.284
MOD_NEK2_1	101	106	PF00069	0.301
MOD_NEK2_1	74	79	PF00069	0.277
MOD_PIKK_1	42	48	PF00454	0.376
MOD_PIKK_1	74	80	PF00454	0.280
MOD_PKA_2	111	117	PF00069	0.428
MOD_PKA_2	28	34	PF00069	0.300
MOD_PKA_2	66	72	PF00069	0.272
MOD_PKB_1	122	130	PF00069	0.417
MOD_Plk_4	66	72	PF00069	0.272
MOD_ProDKin_1	105	111	PF00069	0.344
MOD_SUMO_rev_2	114	120	PF00179	0.436
MOD_SUMO_rev_2	12	17	PF00179	0.345
TRG_DiLeu_BaEn_1	97	102	PF01217	0.276
TRG_ENDOCYTIC_2	59	62	PF00928	0.302
TRG_ER_diArg_1	35	37	PF00400	0.321