LeishMANIAdb
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MORN repeat family protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
MORN repeat family protein
Gene product:
MORN repeat - putative
Species:
Leishmania infantum
UniProt:
A4I327_LEIIN
TriTrypDb:
LINF_270030400
Length:
182

Annotations

Annotations by Jardim et al.

Flagella, MORN repeat

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 12
NetGPI no yes: 0, no: 12
Cellular components
Term Name Level Count
GO:0005930 axoneme 2 2
GO:0097542 ciliary tip 2 1
GO:0110165 cellular anatomical entity 1 2
GO:0005737 cytoplasm 2 1

Expansion

Sequence features

A4I327
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I327

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 4 6 PF00675 0.611
CLV_PCSK_KEX2_1 162 164 PF00082 0.384
CLV_PCSK_KEX2_1 4 6 PF00082 0.594
CLV_PCSK_PC1ET2_1 162 164 PF00082 0.384
CLV_PCSK_PC1ET2_1 4 6 PF00082 0.582
DEG_SPOP_SBC_1 68 72 PF00917 0.678
DEG_SPOP_SBC_1 88 92 PF00917 0.385
DOC_MAPK_FxFP_2 17 20 PF00069 0.355
DOC_PP2B_LxvP_1 110 113 PF13499 0.289
DOC_PP4_FxxP_1 17 20 PF00568 0.355
DOC_USP7_MATH_1 136 140 PF00917 0.251
DOC_USP7_MATH_1 20 24 PF00917 0.349
DOC_USP7_MATH_1 45 49 PF00917 0.677
DOC_USP7_MATH_1 69 73 PF00917 0.686
DOC_USP7_MATH_1 88 92 PF00917 0.450
DOC_USP7_UBL2_3 28 32 PF12436 0.485
LIG_APCC_ABBA_1 153 158 PF00400 0.383
LIG_FHA_1 44 50 PF00498 0.707
LIG_LIR_Apic_2 14 20 PF02991 0.329
LIG_PDZ_Class_2 177 182 PF00595 0.433
LIG_Pex14_1 164 168 PF04695 0.392
LIG_SH2_CRK 84 88 PF00017 0.474
LIG_SH2_STAT5 118 121 PF00017 0.266
LIG_SH2_STAT5 156 159 PF00017 0.296
LIG_SUMO_SIM_par_1 108 114 PF11976 0.275
MOD_CK1_1 111 117 PF00069 0.314
MOD_CK1_1 41 47 PF00069 0.701
MOD_CK1_1 48 54 PF00069 0.712
MOD_CK2_1 136 142 PF00069 0.251
MOD_CK2_1 20 26 PF00069 0.359
MOD_Cter_Amidation 160 163 PF01082 0.330
MOD_GlcNHglycan 113 116 PF01048 0.292
MOD_GlcNHglycan 40 43 PF01048 0.610
MOD_GlcNHglycan 71 74 PF01048 0.661
MOD_GlcNHglycan 91 94 PF01048 0.512
MOD_GSK3_1 41 48 PF00069 0.658
MOD_GSK3_1 64 71 PF00069 0.690
MOD_NEK2_1 127 132 PF00069 0.266
MOD_NEK2_1 13 18 PF00069 0.415
MOD_NEK2_1 87 92 PF00069 0.484
MOD_NEK2_2 20 25 PF00069 0.339
MOD_PKA_2 116 122 PF00069 0.447
MOD_Plk_4 136 142 PF00069 0.360
MOD_Plk_4 20 26 PF00069 0.357
MOD_SUMO_for_1 178 181 PF00179 0.460
TRG_ENDOCYTIC_2 84 87 PF00928 0.438

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IB90 Leptomonas seymouri 62% 100%
A0A0S4KPG9 Bodo saltans 31% 92%
A0A1X0NSQ0 Trypanosomatidae 40% 100%
A0A3Q8IQ71 Leishmania donovani 99% 100%
A0A422NAN4 Trypanosoma rangeli 39% 100%
A4HUC7 Leishmania infantum 34% 100%
C9ZJK1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 39% 100%
E9ACU8 Leishmania major 96% 100%
E9AI39 Leishmania braziliensis 34% 100%
E9AZD7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 93% 100%
Q4QHJ9 Leishmania major 35% 82%
Q6VTH5 Cyprinus carpio 32% 83%
V5BCY8 Trypanosoma cruzi 38% 100%
V5BX28 Trypanosoma cruzi 27% 71%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS