Uncharacterized protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I301_LEIIN

TriTrypDb:

LINF_270026400

Length:

259

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I301

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I301

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	121	123	PF00675	0.643
CLV_NRD_NRD_1	156	158	PF00675	0.513
CLV_NRD_NRD_1	166	168	PF00675	0.424
CLV_NRD_NRD_1	19	21	PF00675	0.592
CLV_NRD_NRD_1	190	192	PF00675	0.542
CLV_NRD_NRD_1	91	93	PF00675	0.512
CLV_PCSK_FUR_1	119	123	PF00082	0.645
CLV_PCSK_KEX2_1	121	123	PF00082	0.643
CLV_PCSK_KEX2_1	156	158	PF00082	0.513
CLV_PCSK_KEX2_1	166	168	PF00082	0.424
CLV_PCSK_KEX2_1	190	192	PF00082	0.551
CLV_PCSK_KEX2_1	91	93	PF00082	0.512
CLV_PCSK_PC7_1	152	158	PF00082	0.454
CLV_PCSK_SKI1_1	173	177	PF00082	0.464
DEG_Nend_Nbox_1	1	3	PF02207	0.562
DOC_USP7_MATH_1	53	57	PF00917	0.656
DOC_USP7_MATH_1	71	75	PF00917	0.494
DOC_USP7_MATH_1	97	101	PF00917	0.631
DOC_WW_Pin1_4	67	72	PF00397	0.684
DOC_WW_Pin1_4	77	82	PF00397	0.572
LIG_14-3-3_CanoR_1	227	235	PF00244	0.474
LIG_14-3-3_CanoR_1	244	254	PF00244	0.451
LIG_14-3-3_CanoR_1	64	70	PF00244	0.587
LIG_FHA_1	253	259	PF00498	0.627
LIG_LIR_Gen_1	248	258	PF02991	0.572
LIG_LIR_Nem_3	248	254	PF02991	0.573
LIG_SH2_CRK	16	20	PF00017	0.611
LIG_SH2_CRK	251	255	PF00017	0.483
LIG_SH2_STAP1	216	220	PF00017	0.547
LIG_SH2_STAT5	216	219	PF00017	0.559
LIG_SH3_1	33	39	PF00018	0.610
LIG_SH3_3	102	108	PF00018	0.667
LIG_SH3_3	33	39	PF00018	0.610
LIG_TRFH_1	9	13	PF08558	0.605
LIG_TYR_ITIM	14	19	PF00017	0.627
LIG_WW_1	30	33	PF00397	0.535
MOD_CK1_1	63	69	PF00069	0.591
MOD_CK1_1	70	76	PF00069	0.582
MOD_CK1_1	77	83	PF00069	0.556
MOD_CK1_1	85	91	PF00069	0.564
MOD_CK2_1	198	204	PF00069	0.604
MOD_CK2_1	41	47	PF00069	0.599
MOD_GlcNHglycan	123	126	PF01048	0.800
MOD_GlcNHglycan	43	46	PF01048	0.627
MOD_GlcNHglycan	53	56	PF01048	0.563
MOD_GlcNHglycan	65	68	PF01048	0.551
MOD_GlcNHglycan	76	79	PF01048	0.550
MOD_GlcNHglycan	99	102	PF01048	0.611
MOD_GSK3_1	169	176	PF00069	0.496
MOD_GSK3_1	226	233	PF00069	0.472
MOD_GSK3_1	51	58	PF00069	0.678
MOD_GSK3_1	63	70	PF00069	0.614
MOD_GSK3_1	76	83	PF00069	0.548
MOD_N-GLC_1	246	251	PF02516	0.573
MOD_NEK2_1	177	182	PF00069	0.529
MOD_NEK2_1	46	51	PF00069	0.620
MOD_NEK2_1	62	67	PF00069	0.670
MOD_NEK2_1	84	89	PF00069	0.569
MOD_PKA_1	121	127	PF00069	0.639
MOD_PKA_2	121	127	PF00069	0.639
MOD_PKA_2	226	232	PF00069	0.635
MOD_PKA_2	51	57	PF00069	0.606
MOD_PKA_2	63	69	PF00069	0.554
MOD_PKB_1	119	127	PF00069	0.641
MOD_PKB_1	167	175	PF00069	0.436
MOD_Plk_1	173	179	PF00069	0.507
MOD_Plk_1	46	52	PF00069	0.664
MOD_ProDKin_1	67	73	PF00069	0.684
MOD_ProDKin_1	77	83	PF00069	0.574
TRG_DiLeu_BaEn_1	219	224	PF01217	0.482
TRG_ENDOCYTIC_2	16	19	PF00928	0.738
TRG_ENDOCYTIC_2	251	254	PF00928	0.492
TRG_ER_diArg_1	118	121	PF00400	0.648
TRG_ER_diArg_1	190	192	PF00400	0.546
TRG_ER_diArg_1	231	234	PF00400	0.525
TRG_ER_diArg_1	238	241	PF00400	0.486
TRG_NLS_MonoExtN_4	156	161	PF00514	0.400
TRG_Pf-PMV_PEXEL_1	240	245	PF00026	0.496

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A1X0NR64	Trypanosomatidae	29%	100%
A0A3S7X0W4	Leishmania donovani	99%	100%
A4HFW8	Leishmania braziliensis	73%	98%
E9ADH3	Leishmania major	92%	100%
E9AZ97	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%