CX9C domain-containing protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I2Z8_LEIIN

TriTrypDb:

LINF_270026100

Length:

140

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I2Z8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I2Z8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	28	32	PF00656	0.490
CLV_NRD_NRD_1	53	55	PF00675	0.455
CLV_NRD_NRD_1	57	59	PF00675	0.449
CLV_NRD_NRD_1	66	68	PF00675	0.465
CLV_PCSK_KEX2_1	53	55	PF00082	0.476
CLV_PCSK_KEX2_1	57	59	PF00082	0.461
CLV_PCSK_PC7_1	53	59	PF00082	0.515
CLV_PCSK_SKI1_1	16	20	PF00082	0.398
DOC_CYCLIN_yClb5_NLxxxL_5	5	14	PF00134	0.508
LIG_14-3-3_CanoR_1	21	30	PF00244	0.491
LIG_BIR_II_1	1	5	PF00653	0.590
LIG_BIR_III_1	1	5	PF00653	0.596
LIG_BIR_III_3	1	5	PF00653	0.596
LIG_NRBOX	9	15	PF00104	0.464
LIG_PCNA_yPIPBox_3	11	21	PF02747	0.429
LIG_SH2_STAT3	121	124	PF00017	0.455
LIG_SH2_STAT3	46	49	PF00017	0.613
LIG_SH2_STAT5	116	119	PF00017	0.386
LIG_SH2_STAT5	121	124	PF00017	0.412
LIG_SH2_STAT5	46	49	PF00017	0.575
LIG_TRAF2_1	61	64	PF00917	0.490
MOD_GlcNHglycan	130	133	PF01048	0.652
MOD_GSK3_1	12	19	PF00069	0.412
MOD_GSK3_1	21	28	PF00069	0.432
MOD_NEK2_2	111	116	PF00069	0.550
MOD_PIKK_1	21	27	PF00454	0.533
MOD_PKA_1	74	80	PF00069	0.481
MOD_PKA_2	128	134	PF00069	0.606
MOD_Plk_1	47	53	PF00069	0.509
MOD_Plk_4	111	117	PF00069	0.548
MOD_Plk_4	42	48	PF00069	0.477
MOD_SUMO_rev_2	71	77	PF00179	0.522
TRG_ENDOCYTIC_2	116	119	PF00928	0.386
TRG_ENDOCYTIC_2	62	65	PF00928	0.493
TRG_ER_diArg_1	56	58	PF00400	0.510

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HY93	Leptomonas seymouri	76%	100%
A0A0S4JQ37	Bodo saltans	63%	100%
A0A1X0NRL4	Trypanosomatidae	73%	100%
A0A3S7X0V7	Leishmania donovani	99%	100%
A0A422NJR7	Trypanosoma rangeli	75%	100%
A4HFW5	Leishmania braziliensis	92%	100%
C9ZJE8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	64%	100%
E9ADH0	Leishmania major	96%	100%
E9AZ94	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%