LeishMANIAdb
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Protein kinase-like protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Protein kinase-like protein
Gene product:
protein kinase-like protein
Species:
Leishmania infantum
UniProt:
A4I2Y6_LEIIN
TriTrypDb:
LINF_270024800
Length:
1742

Annotations

Annotations by Jardim et al.

Protein kinase, kinase-like

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Cellular components
Term Name Level Count
GO:0005634 nucleus 5 1
GO:0005737 cytoplasm 2 1
GO:0032838 plasma membrane bounded cell projection cytoplasm 4 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1
GO:0097014 ciliary plasm 5 1
GO:0099568 cytoplasmic region 3 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

A4I2Y6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I2Y6

Function

Biological processes
Term Name Level Count
GO:0006468 protein phosphorylation 5 6
GO:0006793 phosphorus metabolic process 3 6
GO:0006796 phosphate-containing compound metabolic process 4 6
GO:0006807 nitrogen compound metabolic process 2 6
GO:0008152 metabolic process 1 6
GO:0009987 cellular process 1 6
GO:0016310 phosphorylation 5 6
GO:0019538 protein metabolic process 3 6
GO:0036211 protein modification process 4 6
GO:0043170 macromolecule metabolic process 3 6
GO:0043412 macromolecule modification 4 6
GO:0044237 cellular metabolic process 2 6
GO:0044238 primary metabolic process 2 6
GO:0071704 organic substance metabolic process 2 6
GO:1901564 organonitrogen compound metabolic process 3 6
GO:0000245 spliceosomal complex assembly 7 1
GO:0007165 signal transduction 2 1
GO:0016043 cellular component organization 3 1
GO:0019219 regulation of nucleobase-containing compound metabolic process 5 1
GO:0019222 regulation of metabolic process 3 1
GO:0022607 cellular component assembly 4 1
GO:0022618 ribonucleoprotein complex assembly 6 1
GO:0031323 regulation of cellular metabolic process 4 1
GO:0035556 intracellular signal transduction 3 1
GO:0043933 protein-containing complex organization 4 1
GO:0050684 regulation of mRNA processing 7 1
GO:0050789 regulation of biological process 2 1
GO:0050794 regulation of cellular process 3 1
GO:0051171 regulation of nitrogen compound metabolic process 4 1
GO:0051252 regulation of RNA metabolic process 5 1
GO:0060255 regulation of macromolecule metabolic process 4 1
GO:0065003 protein-containing complex assembly 5 1
GO:0065007 biological regulation 1 1
GO:0071826 ribonucleoprotein complex subunit organization 5 1
GO:0071840 cellular component organization or biogenesis 2 1
GO:0080090 regulation of primary metabolic process 4 1
GO:1903311 regulation of mRNA metabolic process 6 1
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 6
GO:0003824 catalytic activity 1 6
GO:0004672 protein kinase activity 3 6
GO:0005488 binding 1 6
GO:0005524 ATP binding 5 6
GO:0016301 kinase activity 4 6
GO:0016740 transferase activity 2 6
GO:0016772 transferase activity, transferring phosphorus-containing groups 3 6
GO:0016773 phosphotransferase activity, alcohol group as acceptor 4 6
GO:0017076 purine nucleotide binding 4 6
GO:0030554 adenyl nucleotide binding 5 6
GO:0032553 ribonucleotide binding 3 6
GO:0032555 purine ribonucleotide binding 4 6
GO:0032559 adenyl ribonucleotide binding 5 6
GO:0035639 purine ribonucleoside triphosphate binding 4 6
GO:0036094 small molecule binding 2 6
GO:0043167 ion binding 2 6
GO:0043168 anion binding 3 6
GO:0097159 organic cyclic compound binding 2 6
GO:0097367 carbohydrate derivative binding 2 6
GO:0140096 catalytic activity, acting on a protein 2 6
GO:1901265 nucleoside phosphate binding 3 6
GO:1901363 heterocyclic compound binding 2 6
GO:0004674 protein serine/threonine kinase activity 4 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1081 1085 PF00656 0.734
CLV_C14_Caspase3-7 1715 1719 PF00656 0.773
CLV_C14_Caspase3-7 187 191 PF00656 0.483
CLV_C14_Caspase3-7 275 279 PF00656 0.299
CLV_C14_Caspase3-7 824 828 PF00656 0.635
CLV_NRD_NRD_1 113 115 PF00675 0.483
CLV_NRD_NRD_1 1174 1176 PF00675 0.766
CLV_NRD_NRD_1 1673 1675 PF00675 0.796
CLV_NRD_NRD_1 1680 1682 PF00675 0.706
CLV_NRD_NRD_1 247 249 PF00675 0.483
CLV_NRD_NRD_1 333 335 PF00675 0.616
CLV_NRD_NRD_1 339 341 PF00675 0.553
CLV_NRD_NRD_1 392 394 PF00675 0.689
CLV_NRD_NRD_1 48 50 PF00675 0.483
CLV_NRD_NRD_1 602 604 PF00675 0.762
CLV_PCSK_FUR_1 111 115 PF00082 0.483
CLV_PCSK_FUR_1 337 341 PF00082 0.456
CLV_PCSK_KEX2_1 113 115 PF00082 0.483
CLV_PCSK_KEX2_1 1174 1176 PF00082 0.766
CLV_PCSK_KEX2_1 1673 1675 PF00082 0.796
CLV_PCSK_KEX2_1 1680 1682 PF00082 0.706
CLV_PCSK_KEX2_1 247 249 PF00082 0.483
CLV_PCSK_KEX2_1 339 341 PF00082 0.520
CLV_PCSK_KEX2_1 392 394 PF00082 0.729
CLV_PCSK_KEX2_1 48 50 PF00082 0.416
CLV_PCSK_KEX2_1 491 493 PF00082 0.758
CLV_PCSK_KEX2_1 602 604 PF00082 0.762
CLV_PCSK_KEX2_1 651 653 PF00082 0.739
CLV_PCSK_KEX2_1 975 977 PF00082 0.700
CLV_PCSK_PC1ET2_1 491 493 PF00082 0.758
CLV_PCSK_PC1ET2_1 651 653 PF00082 0.739
CLV_PCSK_PC1ET2_1 975 977 PF00082 0.700
CLV_PCSK_SKI1_1 1175 1179 PF00082 0.742
CLV_PCSK_SKI1_1 12 16 PF00082 0.505
CLV_PCSK_SKI1_1 1313 1317 PF00082 0.698
CLV_PCSK_SKI1_1 1463 1467 PF00082 0.610
CLV_PCSK_SKI1_1 291 295 PF00082 0.483
CLV_PCSK_SKI1_1 298 302 PF00082 0.384
CLV_PCSK_SKI1_1 305 309 PF00082 0.294
CLV_PCSK_SKI1_1 495 499 PF00082 0.698
CLV_PCSK_SKI1_1 55 59 PF00082 0.483
CLV_PCSK_SKI1_1 680 684 PF00082 0.614
CLV_PCSK_SKI1_1 69 73 PF00082 0.284
CLV_PCSK_SKI1_1 708 712 PF00082 0.740
CLV_PCSK_SKI1_1 796 800 PF00082 0.791
DEG_APCC_DBOX_1 235 243 PF00400 0.483
DEG_APCC_DBOX_1 297 305 PF00400 0.483
DEG_SCF_FBW7_1 1340 1345 PF00400 0.631
DEG_SCF_FBW7_1 1596 1603 PF00400 0.615
DEG_SCF_FBW7_1 653 660 PF00400 0.807
DEG_SCF_FBW7_2 287 292 PF00400 0.449
DEG_SCF_TRCP1_1 1708 1713 PF00400 0.744
DEG_SPOP_SBC_1 1024 1028 PF00917 0.764
DEG_SPOP_SBC_1 1388 1392 PF00917 0.631
DEG_SPOP_SBC_1 1417 1421 PF00917 0.763
DEG_SPOP_SBC_1 1687 1691 PF00917 0.723
DEG_SPOP_SBC_1 1698 1702 PF00917 0.592
DEG_SPOP_SBC_1 455 459 PF00917 0.701
DEG_SPOP_SBC_1 928 932 PF00917 0.758
DOC_CKS1_1 1119 1124 PF01111 0.746
DOC_CKS1_1 1597 1602 PF01111 0.616
DOC_CKS1_1 274 279 PF01111 0.483
DOC_CKS1_1 703 708 PF01111 0.694
DOC_CKS1_1 985 990 PF01111 0.731
DOC_CYCLIN_RxL_1 1220 1230 PF00134 0.594
DOC_CYCLIN_RxL_1 123 133 PF00134 0.483
DOC_CYCLIN_RxL_1 1309 1321 PF00134 0.693
DOC_CYCLIN_RxL_1 302 309 PF00134 0.510
DOC_CYCLIN_yCln2_LP_2 765 771 PF00134 0.649
DOC_CYCLIN_yCln2_LP_2 985 991 PF00134 0.696
DOC_MAPK_DCC_7 1300 1310 PF00069 0.603
DOC_MAPK_DCC_7 547 557 PF00069 0.751
DOC_MAPK_gen_1 1366 1374 PF00069 0.621
DOC_MAPK_gen_1 1673 1684 PF00069 0.734
DOC_MAPK_gen_1 197 206 PF00069 0.483
DOC_MAPK_gen_1 295 303 PF00069 0.530
DOC_MAPK_gen_1 33 42 PF00069 0.483
DOC_MAPK_gen_1 48 56 PF00069 0.270
DOC_MAPK_gen_1 500 508 PF00069 0.722
DOC_MAPK_gen_1 66 75 PF00069 0.231
DOC_MAPK_HePTP_8 194 206 PF00069 0.483
DOC_MAPK_MEF2A_6 197 206 PF00069 0.483
DOC_MAPK_MEF2A_6 33 42 PF00069 0.483
DOC_MAPK_MEF2A_6 66 75 PF00069 0.483
DOC_MAPK_RevD_3 100 114 PF00069 0.483
DOC_MAPK_RevD_3 478 492 PF00069 0.721
DOC_PP1_RVXF_1 124 131 PF00149 0.483
DOC_PP2B_LxvP_1 1308 1311 PF13499 0.705
DOC_PP2B_LxvP_1 1315 1318 PF13499 0.612
DOC_PP2B_LxvP_1 322 325 PF13499 0.483
DOC_PP2B_LxvP_1 40 43 PF13499 0.399
DOC_PP2B_LxvP_1 765 768 PF13499 0.727
DOC_PP4_FxxP_1 1005 1008 PF00568 0.692
DOC_PP4_FxxP_1 101 104 PF00568 0.483
DOC_PP4_FxxP_1 1344 1347 PF00568 0.726
DOC_PP4_FxxP_1 475 478 PF00568 0.732
DOC_PP4_MxPP_1 1089 1092 PF00568 0.791
DOC_USP7_MATH_1 1016 1020 PF00917 0.520
DOC_USP7_MATH_1 1110 1114 PF00917 0.768
DOC_USP7_MATH_1 1131 1135 PF00917 0.705
DOC_USP7_MATH_1 1154 1158 PF00917 0.615
DOC_USP7_MATH_1 1186 1190 PF00917 0.771
DOC_USP7_MATH_1 1194 1198 PF00917 0.699
DOC_USP7_MATH_1 1206 1210 PF00917 0.537
DOC_USP7_MATH_1 1251 1255 PF00917 0.673
DOC_USP7_MATH_1 1281 1285 PF00917 0.766
DOC_USP7_MATH_1 1311 1315 PF00917 0.723
DOC_USP7_MATH_1 1389 1393 PF00917 0.692
DOC_USP7_MATH_1 1404 1408 PF00917 0.635
DOC_USP7_MATH_1 1444 1448 PF00917 0.720
DOC_USP7_MATH_1 1491 1495 PF00917 0.775
DOC_USP7_MATH_1 1561 1565 PF00917 0.801
DOC_USP7_MATH_1 1567 1571 PF00917 0.704
DOC_USP7_MATH_1 1600 1604 PF00917 0.716
DOC_USP7_MATH_1 1609 1613 PF00917 0.699
DOC_USP7_MATH_1 1615 1619 PF00917 0.620
DOC_USP7_MATH_1 165 169 PF00917 0.483
DOC_USP7_MATH_1 1665 1669 PF00917 0.723
DOC_USP7_MATH_1 1685 1689 PF00917 0.579
DOC_USP7_MATH_1 1698 1702 PF00917 0.594
DOC_USP7_MATH_1 1706 1710 PF00917 0.616
DOC_USP7_MATH_1 257 261 PF00917 0.423
DOC_USP7_MATH_1 434 438 PF00917 0.731
DOC_USP7_MATH_1 460 464 PF00917 0.731
DOC_USP7_MATH_1 478 482 PF00917 0.779
DOC_USP7_MATH_1 573 577 PF00917 0.820
DOC_USP7_MATH_1 657 661 PF00917 0.731
DOC_USP7_MATH_1 689 693 PF00917 0.650
DOC_USP7_MATH_1 715 719 PF00917 0.681
DOC_USP7_MATH_1 732 736 PF00917 0.663
DOC_USP7_MATH_1 787 791 PF00917 0.611
DOC_USP7_MATH_1 84 88 PF00917 0.483
DOC_USP7_MATH_1 996 1000 PF00917 0.786
DOC_USP7_MATH_2 1047 1053 PF00917 0.748
DOC_USP7_UBL2_3 1630 1634 PF12436 0.748
DOC_USP7_UBL2_3 261 265 PF12436 0.416
DOC_USP7_UBL2_3 491 495 PF12436 0.690
DOC_USP7_UBL2_3 55 59 PF12436 0.483
DOC_WW_Pin1_4 1004 1009 PF00397 0.577
DOC_WW_Pin1_4 1014 1019 PF00397 0.648
DOC_WW_Pin1_4 1031 1036 PF00397 0.590
DOC_WW_Pin1_4 1118 1123 PF00397 0.772
DOC_WW_Pin1_4 1161 1166 PF00397 0.650
DOC_WW_Pin1_4 1199 1204 PF00397 0.654
DOC_WW_Pin1_4 1239 1244 PF00397 0.728
DOC_WW_Pin1_4 1249 1254 PF00397 0.670
DOC_WW_Pin1_4 1264 1269 PF00397 0.589
DOC_WW_Pin1_4 1318 1323 PF00397 0.743
DOC_WW_Pin1_4 1324 1329 PF00397 0.699
DOC_WW_Pin1_4 1338 1343 PF00397 0.551
DOC_WW_Pin1_4 1377 1382 PF00397 0.816
DOC_WW_Pin1_4 1458 1463 PF00397 0.780
DOC_WW_Pin1_4 1487 1492 PF00397 0.811
DOC_WW_Pin1_4 1497 1502 PF00397 0.662
DOC_WW_Pin1_4 1509 1514 PF00397 0.629
DOC_WW_Pin1_4 1596 1601 PF00397 0.715
DOC_WW_Pin1_4 1700 1705 PF00397 0.719
DOC_WW_Pin1_4 1734 1739 PF00397 0.756
DOC_WW_Pin1_4 273 278 PF00397 0.483
DOC_WW_Pin1_4 285 290 PF00397 0.313
DOC_WW_Pin1_4 351 356 PF00397 0.692
DOC_WW_Pin1_4 420 425 PF00397 0.744
DOC_WW_Pin1_4 429 434 PF00397 0.818
DOC_WW_Pin1_4 435 440 PF00397 0.702
DOC_WW_Pin1_4 446 451 PF00397 0.565
DOC_WW_Pin1_4 516 521 PF00397 0.622
DOC_WW_Pin1_4 593 598 PF00397 0.816
DOC_WW_Pin1_4 602 607 PF00397 0.709
DOC_WW_Pin1_4 631 636 PF00397 0.765
DOC_WW_Pin1_4 653 658 PF00397 0.741
DOC_WW_Pin1_4 660 665 PF00397 0.708
DOC_WW_Pin1_4 669 674 PF00397 0.567
DOC_WW_Pin1_4 675 680 PF00397 0.604
DOC_WW_Pin1_4 702 707 PF00397 0.760
DOC_WW_Pin1_4 722 727 PF00397 0.523
DOC_WW_Pin1_4 750 755 PF00397 0.640
DOC_WW_Pin1_4 773 778 PF00397 0.776
DOC_WW_Pin1_4 780 785 PF00397 0.757
DOC_WW_Pin1_4 789 794 PF00397 0.627
DOC_WW_Pin1_4 812 817 PF00397 0.780
DOC_WW_Pin1_4 851 856 PF00397 0.731
DOC_WW_Pin1_4 882 887 PF00397 0.770
DOC_WW_Pin1_4 893 898 PF00397 0.646
DOC_WW_Pin1_4 909 914 PF00397 0.578
DOC_WW_Pin1_4 917 922 PF00397 0.736
DOC_WW_Pin1_4 937 942 PF00397 0.535
DOC_WW_Pin1_4 984 989 PF00397 0.729
LIG_14-3-3_CanoR_1 1025 1032 PF00244 0.682
LIG_14-3-3_CanoR_1 1063 1071 PF00244 0.738
LIG_14-3-3_CanoR_1 1111 1119 PF00244 0.776
LIG_14-3-3_CanoR_1 1147 1152 PF00244 0.708
LIG_14-3-3_CanoR_1 119 125 PF00244 0.483
LIG_14-3-3_CanoR_1 1463 1468 PF00244 0.666
LIG_14-3-3_CanoR_1 1477 1483 PF00244 0.736
LIG_14-3-3_CanoR_1 1646 1654 PF00244 0.764
LIG_14-3-3_CanoR_1 1697 1704 PF00244 0.732
LIG_14-3-3_CanoR_1 315 319 PF00244 0.483
LIG_14-3-3_CanoR_1 443 450 PF00244 0.653
LIG_14-3-3_CanoR_1 502 507 PF00244 0.780
LIG_14-3-3_CanoR_1 547 555 PF00244 0.697
LIG_14-3-3_CanoR_1 602 606 PF00244 0.656
LIG_14-3-3_CanoR_1 659 667 PF00244 0.737
LIG_14-3-3_CanoR_1 717 726 PF00244 0.781
LIG_14-3-3_CanoR_1 736 742 PF00244 0.711
LIG_14-3-3_CanoR_1 778 783 PF00244 0.808
LIG_14-3-3_CanoR_1 796 805 PF00244 0.530
LIG_14-3-3_CanoR_1 914 921 PF00244 0.741
LIG_14-3-3_CanoR_1 950 958 PF00244 0.702
LIG_14-3-3_CanoR_1 976 982 PF00244 0.628
LIG_14-3-3_CanoR_1 997 1005 PF00244 0.657
LIG_Actin_WH2_2 1134 1151 PF00022 0.688
LIG_BIR_III_2 570 574 PF00653 0.655
LIG_BRCT_BRCA1_1 1001 1005 PF00533 0.714
LIG_BRCT_BRCA1_1 1067 1071 PF00533 0.711
LIG_BRCT_BRCA1_1 1451 1455 PF00533 0.752
LIG_BRCT_BRCA1_1 263 267 PF00533 0.483
LIG_deltaCOP1_diTrp_1 171 178 PF00928 0.479
LIG_eIF4E_1 67 73 PF01652 0.483
LIG_FHA_1 1051 1057 PF00498 0.685
LIG_FHA_1 1095 1101 PF00498 0.653
LIG_FHA_1 1140 1146 PF00498 0.732
LIG_FHA_1 1273 1279 PF00498 0.742
LIG_FHA_1 1341 1347 PF00498 0.602
LIG_FHA_1 1418 1424 PF00498 0.695
LIG_FHA_1 1471 1477 PF00498 0.744
LIG_FHA_1 1478 1484 PF00498 0.737
LIG_FHA_1 1520 1526 PF00498 0.670
LIG_FHA_1 1537 1543 PF00498 0.656
LIG_FHA_1 1602 1608 PF00498 0.574
LIG_FHA_1 1687 1693 PF00498 0.793
LIG_FHA_1 1734 1740 PF00498 0.680
LIG_FHA_1 367 373 PF00498 0.583
LIG_FHA_1 526 532 PF00498 0.823
LIG_FHA_1 560 566 PF00498 0.647
LIG_FHA_1 750 756 PF00498 0.833
LIG_FHA_1 805 811 PF00498 0.756
LIG_FHA_1 933 939 PF00498 0.697
LIG_FHA_1 969 975 PF00498 0.589
LIG_FHA_2 1290 1296 PF00498 0.663
LIG_FHA_2 315 321 PF00498 0.483
LIG_FHA_2 398 404 PF00498 0.742
LIG_FHA_2 416 422 PF00498 0.535
LIG_FHA_2 447 453 PF00498 0.811
LIG_FHA_2 466 472 PF00498 0.696
LIG_FHA_2 835 841 PF00498 0.779
LIG_Integrin_RGD_1 270 272 PF01839 0.416
LIG_LIR_Apic_2 1002 1008 PF02991 0.693
LIG_LIR_Apic_2 1341 1347 PF02991 0.719
LIG_LIR_Apic_2 196 202 PF02991 0.483
LIG_LIR_Apic_2 472 478 PF02991 0.722
LIG_LIR_Apic_2 916 921 PF02991 0.815
LIG_LIR_Gen_1 1049 1059 PF02991 0.705
LIG_LIR_Gen_1 123 132 PF02991 0.463
LIG_LIR_Gen_1 137 148 PF02991 0.304
LIG_LIR_Gen_1 1452 1462 PF02991 0.756
LIG_LIR_Gen_1 297 308 PF02991 0.483
LIG_LIR_Gen_1 819 828 PF02991 0.608
LIG_LIR_Gen_1 87 94 PF02991 0.483
LIG_LIR_LC3C_4 807 812 PF02991 0.684
LIG_LIR_Nem_3 1049 1054 PF02991 0.711
LIG_LIR_Nem_3 123 127 PF02991 0.463
LIG_LIR_Nem_3 129 135 PF02991 0.418
LIG_LIR_Nem_3 137 143 PF02991 0.304
LIG_LIR_Nem_3 1452 1458 PF02991 0.756
LIG_LIR_Nem_3 297 303 PF02991 0.483
LIG_LIR_Nem_3 32 38 PF02991 0.446
LIG_LIR_Nem_3 663 668 PF02991 0.613
LIG_LIR_Nem_3 819 825 PF02991 0.607
LIG_LIR_Nem_3 87 93 PF02991 0.483
LIG_LIR_Nem_3 955 961 PF02991 0.774
LIG_MLH1_MIPbox_1 263 267 PF16413 0.483
LIG_NRBOX 303 309 PF00104 0.498
LIG_PTAP_UEV_1 1012 1017 PF05743 0.535
LIG_SH2_CRK 918 922 PF00017 0.812
LIG_SH2_GRB2like 266 269 PF00017 0.483
LIG_SH2_NCK_1 20 24 PF00017 0.483
LIG_SH2_STAP1 124 128 PF00017 0.416
LIG_SH2_STAP1 1726 1730 PF00017 0.585
LIG_SH2_STAP1 212 216 PF00017 0.483
LIG_SH2_STAP1 224 228 PF00017 0.313
LIG_SH2_STAP1 262 266 PF00017 0.483
LIG_SH2_STAP1 61 65 PF00017 0.483
LIG_SH2_STAP1 67 71 PF00017 0.398
LIG_SH2_STAP1 90 94 PF00017 0.483
LIG_SH2_STAT3 67 70 PF00017 0.483
LIG_SH2_STAT5 266 269 PF00017 0.483
LIG_SH3_3 1010 1016 PF00018 0.543
LIG_SH3_3 1029 1035 PF00018 0.713
LIG_SH3_3 1116 1122 PF00018 0.738
LIG_SH3_3 1148 1154 PF00018 0.684
LIG_SH3_3 1162 1168 PF00018 0.599
LIG_SH3_3 1190 1196 PF00018 0.724
LIG_SH3_3 1200 1206 PF00018 0.612
LIG_SH3_3 1265 1271 PF00018 0.719
LIG_SH3_3 1322 1328 PF00018 0.696
LIG_SH3_3 1371 1377 PF00018 0.723
LIG_SH3_3 1382 1388 PF00018 0.650
LIG_SH3_3 1485 1491 PF00018 0.742
LIG_SH3_3 1535 1541 PF00018 0.714
LIG_SH3_3 1681 1687 PF00018 0.730
LIG_SH3_3 477 483 PF00018 0.823
LIG_SH3_3 723 729 PF00018 0.653
LIG_SH3_3 751 757 PF00018 0.691
LIG_SH3_3 781 787 PF00018 0.793
LIG_SH3_3 849 855 PF00018 0.700
LIG_SH3_3 891 897 PF00018 0.703
LIG_SH3_3 935 941 PF00018 0.742
LIG_SH3_3 985 991 PF00018 0.792
LIG_SH3_CIN85_PxpxPR_1 1381 1386 PF14604 0.671
LIG_SUMO_SIM_anti_2 1572 1578 PF11976 0.681
LIG_SUMO_SIM_anti_2 522 528 PF11976 0.624
LIG_SUMO_SIM_anti_2 858 866 PF11976 0.618
LIG_SUMO_SIM_par_1 71 77 PF11976 0.483
LIG_TRAF2_1 1197 1200 PF00917 0.796
LIG_TRAF2_1 344 347 PF00917 0.568
LIG_TYR_ITIM 122 127 PF00017 0.416
LIG_UBA3_1 71 80 PF00899 0.416
MOD_CDC14_SPxK_1 634 637 PF00782 0.723
MOD_CDC14_SPxK_1 920 923 PF00782 0.810
MOD_CDK_SPK_2 1004 1009 PF00069 0.793
MOD_CDK_SPK_2 1381 1386 PF00069 0.671
MOD_CDK_SPK_2 1458 1463 PF00069 0.793
MOD_CDK_SPK_2 1497 1502 PF00069 0.771
MOD_CDK_SPK_2 1509 1514 PF00069 0.629
MOD_CDK_SPK_2 1601 1606 PF00069 0.613
MOD_CDK_SPK_2 446 451 PF00069 0.746
MOD_CDK_SPK_2 675 680 PF00069 0.694
MOD_CDK_SPK_2 722 727 PF00069 0.739
MOD_CDK_SPK_2 773 778 PF00069 0.733
MOD_CDK_SPK_2 909 914 PF00069 0.721
MOD_CDK_SPxK_1 285 291 PF00069 0.483
MOD_CDK_SPxK_1 602 608 PF00069 0.778
MOD_CDK_SPxK_1 631 637 PF00069 0.723
MOD_CDK_SPxK_1 653 659 PF00069 0.747
MOD_CDK_SPxK_1 660 666 PF00069 0.658
MOD_CDK_SPxK_1 702 708 PF00069 0.695
MOD_CDK_SPxK_1 917 923 PF00069 0.813
MOD_CDK_SPxxK_3 1601 1608 PF00069 0.693
MOD_CDK_SPxxK_3 516 523 PF00069 0.629
MOD_CDK_SPxxK_3 593 600 PF00069 0.814
MOD_CDK_SPxxK_3 635 642 PF00069 0.612
MOD_CDK_SPxxK_3 789 796 PF00069 0.720
MOD_CK1_1 1014 1020 PF00069 0.562
MOD_CK1_1 1031 1037 PF00069 0.564
MOD_CK1_1 1093 1099 PF00069 0.801
MOD_CK1_1 1115 1121 PF00069 0.770
MOD_CK1_1 1133 1139 PF00069 0.578
MOD_CK1_1 1390 1396 PF00069 0.748
MOD_CK1_1 1407 1413 PF00069 0.581
MOD_CK1_1 1447 1453 PF00069 0.751
MOD_CK1_1 1475 1481 PF00069 0.803
MOD_CK1_1 1490 1496 PF00069 0.596
MOD_CK1_1 1570 1576 PF00069 0.698
MOD_CK1_1 1587 1593 PF00069 0.556
MOD_CK1_1 1610 1616 PF00069 0.680
MOD_CK1_1 1618 1624 PF00069 0.610
MOD_CK1_1 1636 1642 PF00069 0.652
MOD_CK1_1 1645 1651 PF00069 0.619
MOD_CK1_1 1688 1694 PF00069 0.797
MOD_CK1_1 1700 1706 PF00069 0.624
MOD_CK1_1 1717 1723 PF00069 0.737
MOD_CK1_1 1731 1737 PF00069 0.610
MOD_CK1_1 260 266 PF00069 0.478
MOD_CK1_1 446 452 PF00069 0.739
MOD_CK1_1 463 469 PF00069 0.643
MOD_CK1_1 481 487 PF00069 0.771
MOD_CK1_1 514 520 PF00069 0.665
MOD_CK1_1 540 546 PF00069 0.765
MOD_CK1_1 583 589 PF00069 0.779
MOD_CK1_1 591 597 PF00069 0.619
MOD_CK1_1 611 617 PF00069 0.669
MOD_CK1_1 658 664 PF00069 0.786
MOD_CK1_1 737 743 PF00069 0.799
MOD_CK1_1 882 888 PF00069 0.773
MOD_CK1_1 893 899 PF00069 0.645
MOD_CK1_1 909 915 PF00069 0.600
MOD_CK1_1 936 942 PF00069 0.830
MOD_CK1_1 952 958 PF00069 0.568
MOD_CK1_1 999 1005 PF00069 0.733
MOD_CK2_1 1004 1010 PF00069 0.791
MOD_CK2_1 1100 1106 PF00069 0.611
MOD_CK2_1 1194 1200 PF00069 0.757
MOD_CK2_1 1289 1295 PF00069 0.745
MOD_CK2_1 314 320 PF00069 0.483
MOD_CK2_1 397 403 PF00069 0.770
MOD_CK2_1 409 415 PF00069 0.685
MOD_CK2_1 951 957 PF00069 0.717
MOD_Cter_Amidation 488 491 PF01082 0.621
MOD_DYRK1A_RPxSP_1 593 597 PF00069 0.751
MOD_GlcNHglycan 1013 1016 PF01048 0.647
MOD_GlcNHglycan 1067 1070 PF01048 0.671
MOD_GlcNHglycan 1097 1100 PF01048 0.788
MOD_GlcNHglycan 1102 1105 PF01048 0.709
MOD_GlcNHglycan 1114 1117 PF01048 0.570
MOD_GlcNHglycan 1133 1136 PF01048 0.495
MOD_GlcNHglycan 1161 1164 PF01048 0.645
MOD_GlcNHglycan 1188 1191 PF01048 0.716
MOD_GlcNHglycan 1281 1284 PF01048 0.738
MOD_GlcNHglycan 1363 1366 PF01048 0.772
MOD_GlcNHglycan 1406 1409 PF01048 0.677
MOD_GlcNHglycan 1446 1449 PF01048 0.704
MOD_GlcNHglycan 1483 1486 PF01048 0.801
MOD_GlcNHglycan 1493 1496 PF01048 0.679
MOD_GlcNHglycan 1503 1506 PF01048 0.528
MOD_GlcNHglycan 1527 1530 PF01048 0.708
MOD_GlcNHglycan 1582 1585 PF01048 0.796
MOD_GlcNHglycan 1615 1618 PF01048 0.685
MOD_GlcNHglycan 1636 1639 PF01048 0.690
MOD_GlcNHglycan 1707 1711 PF01048 0.750
MOD_GlcNHglycan 179 182 PF01048 0.483
MOD_GlcNHglycan 402 407 PF01048 0.740
MOD_GlcNHglycan 445 448 PF01048 0.796
MOD_GlcNHglycan 462 465 PF01048 0.563
MOD_GlcNHglycan 480 483 PF01048 0.768
MOD_GlcNHglycan 516 519 PF01048 0.699
MOD_GlcNHglycan 548 551 PF01048 0.740
MOD_GlcNHglycan 577 580 PF01048 0.762
MOD_GlcNHglycan 582 585 PF01048 0.692
MOD_GlcNHglycan 590 593 PF01048 0.552
MOD_GlcNHglycan 620 623 PF01048 0.712
MOD_GlcNHglycan 646 649 PF01048 0.764
MOD_GlcNHglycan 660 663 PF01048 0.666
MOD_GlcNHglycan 686 689 PF01048 0.684
MOD_GlcNHglycan 719 722 PF01048 0.660
MOD_GlcNHglycan 82 85 PF01048 0.451
MOD_GlcNHglycan 934 938 PF01048 0.669
MOD_GSK3_1 1019 1026 PF00069 0.753
MOD_GSK3_1 1050 1057 PF00069 0.650
MOD_GSK3_1 1059 1066 PF00069 0.652
MOD_GSK3_1 1067 1074 PF00069 0.575
MOD_GSK3_1 1078 1085 PF00069 0.576
MOD_GSK3_1 1090 1097 PF00069 0.612
MOD_GSK3_1 1106 1113 PF00069 0.571
MOD_GSK3_1 1114 1121 PF00069 0.674
MOD_GSK3_1 1129 1136 PF00069 0.568
MOD_GSK3_1 1166 1173 PF00069 0.673
MOD_GSK3_1 1194 1201 PF00069 0.757
MOD_GSK3_1 1206 1213 PF00069 0.629
MOD_GSK3_1 1219 1226 PF00069 0.645
MOD_GSK3_1 1279 1286 PF00069 0.799
MOD_GSK3_1 1320 1327 PF00069 0.702
MOD_GSK3_1 1336 1343 PF00069 0.579
MOD_GSK3_1 1357 1364 PF00069 0.686
MOD_GSK3_1 1377 1384 PF00069 0.817
MOD_GSK3_1 1387 1394 PF00069 0.668
MOD_GSK3_1 1404 1411 PF00069 0.567
MOD_GSK3_1 1412 1419 PF00069 0.703
MOD_GSK3_1 1443 1450 PF00069 0.711
MOD_GSK3_1 1472 1479 PF00069 0.737
MOD_GSK3_1 1487 1494 PF00069 0.585
MOD_GSK3_1 1497 1504 PF00069 0.630
MOD_GSK3_1 1557 1564 PF00069 0.734
MOD_GSK3_1 1580 1587 PF00069 0.657
MOD_GSK3_1 1596 1603 PF00069 0.708
MOD_GSK3_1 1609 1616 PF00069 0.592
MOD_GSK3_1 1632 1639 PF00069 0.740
MOD_GSK3_1 1641 1648 PF00069 0.691
MOD_GSK3_1 1686 1693 PF00069 0.794
MOD_GSK3_1 1706 1713 PF00069 0.763
MOD_GSK3_1 1728 1735 PF00069 0.764
MOD_GSK3_1 188 195 PF00069 0.399
MOD_GSK3_1 257 264 PF00069 0.493
MOD_GSK3_1 397 404 PF00069 0.781
MOD_GSK3_1 415 422 PF00069 0.626
MOD_GSK3_1 446 453 PF00069 0.737
MOD_GSK3_1 454 461 PF00069 0.723
MOD_GSK3_1 465 472 PF00069 0.612
MOD_GSK3_1 510 517 PF00069 0.749
MOD_GSK3_1 537 544 PF00069 0.725
MOD_GSK3_1 560 567 PF00069 0.669
MOD_GSK3_1 607 614 PF00069 0.688
MOD_GSK3_1 631 638 PF00069 0.853
MOD_GSK3_1 653 660 PF00069 0.849
MOD_GSK3_1 669 676 PF00069 0.551
MOD_GSK3_1 689 696 PF00069 0.509
MOD_GSK3_1 728 735 PF00069 0.777
MOD_GSK3_1 769 776 PF00069 0.786
MOD_GSK3_1 80 87 PF00069 0.443
MOD_GSK3_1 826 833 PF00069 0.812
MOD_GSK3_1 851 858 PF00069 0.806
MOD_GSK3_1 878 885 PF00069 0.786
MOD_GSK3_1 902 909 PF00069 0.750
MOD_GSK3_1 913 920 PF00069 0.677
MOD_GSK3_1 928 935 PF00069 0.633
MOD_GSK3_1 949 956 PF00069 0.706
MOD_LATS_1 259 265 PF00433 0.483
MOD_LATS_1 399 405 PF00433 0.754
MOD_LATS_1 78 84 PF00433 0.416
MOD_N-GLC_1 1394 1399 PF02516 0.722
MOD_N-GLC_1 1412 1417 PF02516 0.581
MOD_N-GLC_1 1463 1468 PF02516 0.611
MOD_N-GLC_1 29 34 PF02516 0.483
MOD_N-GLC_1 397 402 PF02516 0.772
MOD_N-GLC_1 478 483 PF02516 0.615
MOD_N-GLC_1 630 635 PF02516 0.656
MOD_N-GLC_1 653 658 PF02516 0.744
MOD_N-GLC_2 1065 1067 PF02516 0.701
MOD_N-GLC_2 386 388 PF02516 0.697
MOD_NEK2_1 1050 1055 PF00069 0.687
MOD_NEK2_1 1071 1076 PF00069 0.694
MOD_NEK2_1 1198 1203 PF00069 0.769
MOD_NEK2_1 1210 1215 PF00069 0.649
MOD_NEK2_1 1289 1294 PF00069 0.730
MOD_NEK2_1 134 139 PF00069 0.533
MOD_NEK2_1 1451 1456 PF00069 0.653
MOD_NEK2_1 1476 1481 PF00069 0.621
MOD_NEK2_1 1520 1525 PF00069 0.670
MOD_NEK2_1 193 198 PF00069 0.483
MOD_NEK2_1 366 371 PF00069 0.680
MOD_NEK2_1 409 414 PF00069 0.748
MOD_NEK2_1 456 461 PF00069 0.731
MOD_NEK2_1 560 565 PF00069 0.661
MOD_NEK2_1 630 635 PF00069 0.722
MOD_NEK2_1 667 672 PF00069 0.793
MOD_NEK2_1 683 688 PF00069 0.569
MOD_NEK2_1 693 698 PF00069 0.692
MOD_NEK2_1 716 721 PF00069 0.740
MOD_NEK2_1 749 754 PF00069 0.718
MOD_NEK2_1 856 861 PF00069 0.705
MOD_NEK2_1 890 895 PF00069 0.784
MOD_NEK2_1 944 949 PF00069 0.742
MOD_NEK2_1 951 956 PF00069 0.681
MOD_NEK2_2 1615 1620 PF00069 0.635
MOD_NEK2_2 902 907 PF00069 0.732
MOD_NEK2_2 970 975 PF00069 0.671
MOD_PIKK_1 1133 1139 PF00454 0.765
MOD_PIKK_1 1225 1231 PF00454 0.727
MOD_PIKK_1 1300 1306 PF00454 0.794
MOD_PIKK_1 1549 1555 PF00454 0.808
MOD_PIKK_1 1665 1671 PF00454 0.716
MOD_PIKK_1 1690 1696 PF00454 0.799
MOD_PIKK_1 611 617 PF00454 0.698
MOD_PIKK_1 625 631 PF00454 0.693
MOD_PIKK_1 787 793 PF00454 0.608
MOD_PIKK_1 830 836 PF00454 0.632
MOD_PIKK_1 989 995 PF00454 0.790
MOD_PIKK_1 996 1002 PF00454 0.699
MOD_PK_1 1147 1153 PF00069 0.745
MOD_PK_1 1370 1376 PF00069 0.628
MOD_PK_1 502 508 PF00069 0.637
MOD_PKA_1 491 497 PF00069 0.693
MOD_PKA_2 1024 1030 PF00069 0.762
MOD_PKA_2 1110 1116 PF00069 0.782
MOD_PKA_2 1159 1165 PF00069 0.742
MOD_PKA_2 1361 1367 PF00069 0.635
MOD_PKA_2 1476 1482 PF00069 0.804
MOD_PKA_2 1588 1594 PF00069 0.767
MOD_PKA_2 1645 1651 PF00069 0.766
MOD_PKA_2 1663 1669 PF00069 0.534
MOD_PKA_2 1685 1691 PF00069 0.777
MOD_PKA_2 1713 1719 PF00069 0.658
MOD_PKA_2 280 286 PF00069 0.525
MOD_PKA_2 314 320 PF00069 0.483
MOD_PKA_2 366 372 PF00069 0.780
MOD_PKA_2 450 456 PF00069 0.736
MOD_PKA_2 491 497 PF00069 0.697
MOD_PKA_2 546 552 PF00069 0.652
MOD_PKA_2 580 586 PF00069 0.813
MOD_PKA_2 588 594 PF00069 0.708
MOD_PKA_2 601 607 PF00069 0.625
MOD_PKA_2 658 664 PF00069 0.768
MOD_PKA_2 716 722 PF00069 0.781
MOD_PKA_2 84 90 PF00069 0.483
MOD_PKA_2 890 896 PF00069 0.765
MOD_PKA_2 913 919 PF00069 0.765
MOD_PKA_2 949 955 PF00069 0.790
MOD_PKA_2 996 1002 PF00069 0.651
MOD_PKB_1 1221 1229 PF00069 0.678
MOD_PKB_1 500 508 PF00069 0.788
MOD_Plk_1 1223 1229 PF00069 0.777
MOD_Plk_1 128 134 PF00069 0.483
MOD_Plk_1 1394 1400 PF00069 0.721
MOD_Plk_1 1463 1469 PF00069 0.642
MOD_Plk_1 165 171 PF00069 0.483
MOD_Plk_1 1717 1723 PF00069 0.727
MOD_Plk_1 237 243 PF00069 0.483
MOD_Plk_1 878 884 PF00069 0.750
MOD_Plk_2-3 373 379 PF00069 0.615
MOD_Plk_4 179 185 PF00069 0.483
MOD_Plk_4 806 812 PF00069 0.724
MOD_Plk_4 902 908 PF00069 0.729
MOD_ProDKin_1 1004 1010 PF00069 0.574
MOD_ProDKin_1 1014 1020 PF00069 0.650
MOD_ProDKin_1 1031 1037 PF00069 0.591
MOD_ProDKin_1 1118 1124 PF00069 0.771
MOD_ProDKin_1 1161 1167 PF00069 0.648
MOD_ProDKin_1 1199 1205 PF00069 0.652
MOD_ProDKin_1 1239 1245 PF00069 0.730
MOD_ProDKin_1 1249 1255 PF00069 0.671
MOD_ProDKin_1 1264 1270 PF00069 0.589
MOD_ProDKin_1 1318 1324 PF00069 0.745
MOD_ProDKin_1 1338 1344 PF00069 0.630
MOD_ProDKin_1 1377 1383 PF00069 0.817
MOD_ProDKin_1 1458 1464 PF00069 0.780
MOD_ProDKin_1 1487 1493 PF00069 0.811
MOD_ProDKin_1 1497 1503 PF00069 0.664
MOD_ProDKin_1 1509 1515 PF00069 0.628
MOD_ProDKin_1 1596 1602 PF00069 0.714
MOD_ProDKin_1 1700 1706 PF00069 0.721
MOD_ProDKin_1 1734 1740 PF00069 0.757
MOD_ProDKin_1 273 279 PF00069 0.483
MOD_ProDKin_1 285 291 PF00069 0.313
MOD_ProDKin_1 351 357 PF00069 0.700
MOD_ProDKin_1 420 426 PF00069 0.745
MOD_ProDKin_1 429 435 PF00069 0.819
MOD_ProDKin_1 446 452 PF00069 0.564
MOD_ProDKin_1 516 522 PF00069 0.624
MOD_ProDKin_1 593 599 PF00069 0.814
MOD_ProDKin_1 602 608 PF00069 0.707
MOD_ProDKin_1 631 637 PF00069 0.765
MOD_ProDKin_1 653 659 PF00069 0.743
MOD_ProDKin_1 660 666 PF00069 0.709
MOD_ProDKin_1 669 675 PF00069 0.567
MOD_ProDKin_1 702 708 PF00069 0.762
MOD_ProDKin_1 722 728 PF00069 0.522
MOD_ProDKin_1 750 756 PF00069 0.638
MOD_ProDKin_1 773 779 PF00069 0.777
MOD_ProDKin_1 780 786 PF00069 0.754
MOD_ProDKin_1 789 795 PF00069 0.625
MOD_ProDKin_1 812 818 PF00069 0.780
MOD_ProDKin_1 851 857 PF00069 0.731
MOD_ProDKin_1 882 888 PF00069 0.769
MOD_ProDKin_1 893 899 PF00069 0.646
MOD_ProDKin_1 909 915 PF00069 0.578
MOD_ProDKin_1 917 923 PF00069 0.737
MOD_ProDKin_1 937 943 PF00069 0.535
MOD_ProDKin_1 984 990 PF00069 0.730
MOD_SUMO_for_1 152 155 PF00179 0.483
MOD_SUMO_for_1 57 60 PF00179 0.483
MOD_SUMO_for_1 65 68 PF00179 0.369
MOD_SUMO_rev_2 1286 1294 PF00179 0.771
MOD_SUMO_rev_2 815 823 PF00179 0.693
TRG_DiLeu_BaEn_1 299 304 PF01217 0.449
TRG_DiLeu_BaEn_1 68 73 PF01217 0.483
TRG_DiLeu_BaEn_2 135 141 PF01217 0.483
TRG_DiLeu_BaEn_2 295 301 PF01217 0.299
TRG_DiLeu_BaEn_2 96 102 PF01217 0.483
TRG_DiLeu_BaLyEn_6 1241 1246 PF01217 0.584
TRG_DiLeu_BaLyEn_6 663 668 PF01217 0.729
TRG_ENDOCYTIC_2 124 127 PF00928 0.456
TRG_ENDOCYTIC_2 132 135 PF00928 0.396
TRG_ENDOCYTIC_2 20 23 PF00928 0.483
TRG_ENDOCYTIC_2 35 38 PF00928 0.270
TRG_ENDOCYTIC_2 665 668 PF00928 0.615
TRG_ENDOCYTIC_2 90 93 PF00928 0.483
TRG_ER_diArg_1 110 113 PF00400 0.483
TRG_ER_diArg_1 1679 1681 PF00400 0.779
TRG_ER_diArg_1 247 249 PF00400 0.483
TRG_ER_diArg_1 329 332 PF00400 0.564
TRG_ER_diArg_1 337 340 PF00400 0.559
TRG_ER_diArg_1 499 502 PF00400 0.797
TRG_ER_diArg_1 923 926 PF00400 0.810
TRG_NES_CRM1_1 320 336 PF08389 0.519

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8ICT0 Leishmania donovani 99% 100%
A4HG43 Leishmania braziliensis 55% 99%
E9ADF7 Leishmania major 85% 99%
E9AZ80 Leishmania mexicana (strain MHOM/GT/2001/U1103) 81% 99%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS