LeishMANIAdb
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Ferritin

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Ferritin
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4I2X8_LEIIN
TriTrypDb:
LINF_270027900
Length:
82

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I2X8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I2X8

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 6 8 PF00675 0.531
DEG_APCC_DBOX_1 37 45 PF00400 0.616
DEG_Nend_UBRbox_2 1 3 PF02207 0.619
DOC_MAPK_gen_1 7 14 PF00069 0.514
DOC_MAPK_MEF2A_6 7 14 PF00069 0.518
DOC_WW_Pin1_4 59 64 PF00397 0.582
DOC_WW_Pin1_4 73 78 PF00397 0.551
LIG_14-3-3_CanoR_1 33 38 PF00244 0.483
LIG_FHA_2 4 10 PF00498 0.660
LIG_Integrin_RGD_1 78 80 PF01839 0.611
LIG_PCNA_yPIPBox_3 20 33 PF02747 0.480
LIG_SH2_CRK 28 32 PF00017 0.477
LIG_SH2_GRB2like 27 30 PF00017 0.616
LIG_SH2_STAT5 43 46 PF00017 0.562
LIG_SUMO_SIM_anti_2 9 14 PF11976 0.510
LIG_TRAF2_1 15 18 PF00917 0.494
LIG_TYR_ITIM 26 31 PF00017 0.484
MOD_CDK_SPK_2 73 78 PF00069 0.577
MOD_CK1_1 67 73 PF00069 0.568
MOD_CK2_1 3 9 PF00069 0.670
MOD_NEK2_1 64 69 PF00069 0.608
MOD_ProDKin_1 59 65 PF00069 0.587
MOD_ProDKin_1 73 79 PF00069 0.553
TRG_ENDOCYTIC_2 27 30 PF00928 0.512
TRG_ER_diArg_1 32 35 PF00400 0.482

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S7X0Y8 Leishmania donovani 100% 100%
A4HFY5 Leishmania braziliensis 91% 100%
E9ADI8 Leishmania major 95% 100%
E9AZB4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 93% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS