N-acetyltransferase domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

GNAT acetyltransferase - putative

Species:

Leishmania infantum

UniProt:

A4I2U6_LEIIN

TriTrypDb:

LINF_270022200

Length:

438

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I2U6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I2U6

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	1
GO:0016740	transferase activity	2	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	111	113	PF00675	0.542
CLV_NRD_NRD_1	138	140	PF00675	0.489
CLV_NRD_NRD_1	187	189	PF00675	0.431
CLV_NRD_NRD_1	295	297	PF00675	0.273
CLV_NRD_NRD_1	321	323	PF00675	0.357
CLV_NRD_NRD_1	34	36	PF00675	0.561
CLV_NRD_NRD_1	383	385	PF00675	0.273
CLV_PCSK_KEX2_1	111	113	PF00082	0.542
CLV_PCSK_KEX2_1	138	140	PF00082	0.489
CLV_PCSK_KEX2_1	295	297	PF00082	0.273
CLV_PCSK_KEX2_1	34	36	PF00082	0.561
CLV_PCSK_KEX2_1	383	385	PF00082	0.405
CLV_PCSK_KEX2_1	400	402	PF00082	0.321
CLV_PCSK_PC1ET2_1	400	402	PF00082	0.321
CLV_PCSK_PC7_1	30	36	PF00082	0.563
CLV_PCSK_SKI1_1	130	134	PF00082	0.474
CLV_PCSK_SKI1_1	145	149	PF00082	0.447
CLV_PCSK_SKI1_1	196	200	PF00082	0.273
CLV_PCSK_SKI1_1	209	213	PF00082	0.225
CLV_PCSK_SKI1_1	322	326	PF00082	0.273
CLV_PCSK_SKI1_1	393	397	PF00082	0.369
DEG_APCC_DBOX_1	392	400	PF00400	0.273
DEG_Nend_Nbox_1	1	3	PF02207	0.577
DEG_SPOP_SBC_1	24	28	PF00917	0.599
DOC_CYCLIN_RxL_1	139	151	PF00134	0.488
DOC_CYCLIN_RxL_1	381	391	PF00134	0.273
DOC_CYCLIN_yCln2_LP_2	258	264	PF00134	0.273
DOC_CYCLIN_yCln2_LP_2	56	62	PF00134	0.546
DOC_MAPK_DCC_7	54	62	PF00069	0.549
DOC_MAPK_DCC_7	7	15	PF00069	0.563
DOC_MAPK_FxFP_2	199	202	PF00069	0.273
DOC_MAPK_gen_1	231	238	PF00069	0.273
DOC_MAPK_MEF2A_6	231	238	PF00069	0.273
DOC_PP1_RVXF_1	128	135	PF00149	0.465
DOC_PP1_RVXF_1	341	348	PF00149	0.273
DOC_PP2B_LxvP_1	258	261	PF13499	0.273
DOC_PP4_FxxP_1	126	129	PF00568	0.517
DOC_PP4_FxxP_1	199	202	PF00568	0.273
DOC_USP7_MATH_1	202	206	PF00917	0.273
DOC_USP7_MATH_1	288	292	PF00917	0.273
DOC_USP7_MATH_1	359	363	PF00917	0.501
DOC_USP7_MATH_1	75	79	PF00917	0.529
DOC_WW_Pin1_4	171	176	PF00397	0.500
DOC_WW_Pin1_4	271	276	PF00397	0.273
DOC_WW_Pin1_4	424	429	PF00397	0.273
DOC_WW_Pin1_4	47	52	PF00397	0.557
DOC_WW_Pin1_4	5	10	PF00397	0.684
DOC_WW_Pin1_4	55	60	PF00397	0.520
LIG_14-3-3_CanoR_1	103	107	PF00244	0.533
LIG_14-3-3_CanoR_1	111	119	PF00244	0.517
LIG_14-3-3_CanoR_1	168	176	PF00244	0.501
LIG_14-3-3_CanoR_1	222	230	PF00244	0.273
LIG_14-3-3_CanoR_1	231	237	PF00244	0.240
LIG_14-3-3_CanoR_1	76	81	PF00244	0.529
LIG_Actin_WH2_2	32	49	PF00022	0.559
LIG_BRCT_BRCA1_1	149	153	PF00533	0.508
LIG_BRCT_BRCA1_1	169	173	PF00533	0.426
LIG_eIF4E_1	142	148	PF01652	0.488
LIG_FHA_1	233	239	PF00498	0.273
LIG_FHA_1	253	259	PF00498	0.199
LIG_FHA_1	312	318	PF00498	0.477
LIG_FHA_1	352	358	PF00498	0.302
LIG_GBD_Chelix_1	250	258	PF00786	0.273
LIG_LIR_Apic_2	125	129	PF02991	0.485
LIG_LIR_LC3C_4	255	260	PF02991	0.273
LIG_LIR_Nem_3	170	176	PF02991	0.498
LIG_LIR_Nem_3	265	269	PF02991	0.273
LIG_LIR_Nem_3	427	432	PF02991	0.273
LIG_LYPXL_yS_3	283	286	PF13949	0.273
LIG_MYND_1	275	279	PF01753	0.273
LIG_Pex14_2	144	148	PF04695	0.496
LIG_SH2_NCK_1	169	173	PF00017	0.499
LIG_SH2_SRC	178	181	PF00017	0.505
LIG_SH2_STAP1	142	146	PF00017	0.480
LIG_SH2_STAP1	169	173	PF00017	0.499
LIG_SH2_STAP1	25	29	PF00017	0.584
LIG_SH2_STAT5	135	138	PF00017	0.479
LIG_SH2_STAT5	25	28	PF00017	0.586
LIG_SH2_STAT5	280	283	PF00017	0.273
LIG_SH2_STAT5	308	311	PF00017	0.273
LIG_SH2_STAT5	423	426	PF00017	0.273
LIG_SH2_STAT5	432	435	PF00017	0.332
LIG_SH3_3	258	264	PF00018	0.273
LIG_SH3_3	306	312	PF00018	0.273
LIG_SH3_3	6	12	PF00018	0.667
LIG_TYR_ITIM	281	286	PF00017	0.273
LIG_UBA3_1	395	400	PF00899	0.273
LIG_ULM_U2AF65_1	322	327	PF00076	0.273
MOD_CDK_SPxK_1	424	430	PF00069	0.273
MOD_CDK_SPxxK_3	271	278	PF00069	0.273
MOD_CDK_SPxxK_3	47	54	PF00069	0.558
MOD_CK1_1	102	108	PF00069	0.532
MOD_CK1_1	252	258	PF00069	0.273
MOD_CK1_1	42	48	PF00069	0.555
MOD_CK1_1	58	64	PF00069	0.481
MOD_CK1_1	79	85	PF00069	0.523
MOD_CK2_1	207	213	PF00069	0.273
MOD_Cter_Amidation	136	139	PF01082	0.486
MOD_GlcNHglycan	104	107	PF01048	0.531
MOD_GlcNHglycan	169	172	PF01048	0.496
MOD_GlcNHglycan	209	212	PF01048	0.273
MOD_GlcNHglycan	224	227	PF01048	0.218
MOD_GlcNHglycan	251	254	PF01048	0.273
MOD_GlcNHglycan	390	393	PF01048	0.285
MOD_GlcNHglycan	413	416	PF01048	0.299
MOD_GSK3_1	113	120	PF00069	0.550
MOD_GSK3_1	14	21	PF00069	0.762
MOD_GSK3_1	147	154	PF00069	0.507
MOD_GSK3_1	163	170	PF00069	0.445
MOD_GSK3_1	217	224	PF00069	0.273
MOD_GSK3_1	24	31	PF00069	0.699
MOD_GSK3_1	249	256	PF00069	0.273
MOD_GSK3_1	284	291	PF00069	0.273
MOD_GSK3_1	42	49	PF00069	0.489
MOD_GSK3_1	75	82	PF00069	0.523
MOD_N-GLC_1	3	8	PF02516	0.516
MOD_N-GLC_1	42	47	PF02516	0.556
MOD_N-GLC_1	76	81	PF02516	0.529
MOD_NEK2_1	2	7	PF00069	0.555
MOD_NEK2_1	388	393	PF00069	0.273
MOD_NEK2_1	39	44	PF00069	0.561
MOD_NEK2_1	421	426	PF00069	0.273
MOD_NEK2_1	46	51	PF00069	0.532
MOD_NEK2_2	217	222	PF00069	0.273
MOD_NEK2_2	226	231	PF00069	0.240
MOD_OFUCOSY	160	167	PF10250	0.506
MOD_PIKK_1	14	20	PF00454	0.561
MOD_PK_1	76	82	PF00069	0.524
MOD_PKA_2	102	108	PF00069	0.532
MOD_PKA_2	110	116	PF00069	0.512
MOD_PKA_2	167	173	PF00069	0.502
MOD_PKA_2	221	227	PF00069	0.273
MOD_PKA_2	232	238	PF00069	0.232
MOD_PKA_2	351	357	PF00069	0.297
MOD_PKA_2	46	52	PF00069	0.557
MOD_PKA_2	75	81	PF00069	0.527
MOD_Plk_1	42	48	PF00069	0.555
MOD_Plk_1	76	82	PF00069	0.524
MOD_Plk_4	202	208	PF00069	0.273
MOD_Plk_4	254	260	PF00069	0.273
MOD_ProDKin_1	171	177	PF00069	0.501
MOD_ProDKin_1	271	277	PF00069	0.273
MOD_ProDKin_1	424	430	PF00069	0.273
MOD_ProDKin_1	47	53	PF00069	0.558
MOD_ProDKin_1	5	11	PF00069	0.688
MOD_ProDKin_1	55	61	PF00069	0.518
TRG_DiLeu_BaLyEn_6	390	395	PF01217	0.273
TRG_DiLeu_LyEn_5	265	270	PF01217	0.273
TRG_ENDOCYTIC_2	283	286	PF00928	0.273
TRG_ER_diArg_1	110	112	PF00400	0.538
TRG_ER_diArg_1	230	233	PF00400	0.273
TRG_ER_diArg_1	294	296	PF00400	0.273
TRG_ER_diArg_1	34	36	PF00400	0.561
TRG_NES_CRM1_1	249	263	PF08389	0.273
TRG_NLS_MonoExtN_4	320	326	PF00514	0.273
TRG_Pf-PMV_PEXEL_1	295	299	PF00026	0.273
TRG_Pf-PMV_PEXEL_1	393	397	PF00026	0.369

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IDD2	Leishmania donovani	99%	100%