F-box only protein 22

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I2U2_LEIIN

TriTrypDb:

LINF_270020700

Length:

144


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Could not find GO cellular_component term for this entry.

A4I2U2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I2U2


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	52	56	PF00656	0.362
CLV_NRD_NRD_1	86	88	PF00675	0.440
CLV_PCSK_SKI1_1	124	128	PF00082	0.389
CLV_PCSK_SKI1_1	3	7	PF00082	0.450
CLV_PCSK_SKI1_1	54	58	PF00082	0.397
DEG_APCC_DBOX_1	123	131	PF00400	0.352
DOC_MAPK_MEF2A_6	120	127	PF00069	0.348
DOC_PIKK_1	84	92	PF02985	0.499
LIG_14-3-3_CanoR_1	3	8	PF00244	0.477
LIG_BIR_II_1	1	5	PF00653	0.504
LIG_eIF4E_1	112	118	PF01652	0.399
LIG_FHA_1	4	10	PF00498	0.438
LIG_FHA_2	129	135	PF00498	0.518
LIG_FHA_2	8	14	PF00498	0.340
LIG_LIR_Apic_2	10	14	PF02991	0.376
LIG_LIR_Nem_3	55	61	PF02991	0.368
LIG_LIR_Nem_3	84	89	PF02991	0.404
LIG_NRBOX	4	10	PF00104	0.322
LIG_SH2_CRK	58	62	PF00017	0.378
LIG_SH2_CRK	86	90	PF00017	0.393
LIG_SH2_NCK_1	11	15	PF00017	0.371
LIG_SH2_NCK_1	112	116	PF00017	0.390
LIG_SH2_SRC	11	14	PF00017	0.360
LIG_SH2_SRC	73	76	PF00017	0.350
LIG_SH2_STAT5	73	76	PF00017	0.376
LIG_SUMO_SIM_par_1	5	10	PF11976	0.319
LIG_TRAF2_1	131	134	PF00917	0.463
LIG_UBA3_1	64	68	PF00899	0.514
MOD_CK1_1	136	142	PF00069	0.629
MOD_CK2_1	128	134	PF00069	0.417
MOD_CK2_1	78	84	PF00069	0.408
MOD_GSK3_1	133	140	PF00069	0.695
MOD_GSK3_1	3	10	PF00069	0.460
MOD_N-GLC_1	49	54	PF02516	0.442
MOD_NEK2_1	57	62	PF00069	0.370
MOD_NEK2_1	78	83	PF00069	0.527
MOD_NEK2_1	92	97	PF00069	0.451
MOD_NEK2_2	38	43	PF00069	0.416
MOD_PIKK_1	78	84	PF00454	0.408
MOD_Plk_1	133	139	PF00069	0.492
MOD_Plk_4	3	9	PF00069	0.445
TRG_ENDOCYTIC_2	112	115	PF00928	0.413
TRG_ENDOCYTIC_2	58	61	PF00928	0.372
TRG_ENDOCYTIC_2	86	89	PF00928	0.399
TRG_NES_CRM1_1	55	71	PF08389	0.408


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5C5	Leptomonas seymouri	86%	100%
A0A1X0P4D7	Trypanosomatidae	77%	100%
A0A3Q8IGC5	Leishmania donovani	100%	100%
A0A422NFQ4	Trypanosoma rangeli	73%	100%
A4HFR7	Leishmania braziliensis	91%	99%
D0A608	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	71%	100%
E9ADC1	Leishmania major	97%	100%
E9AZ45	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%