Retinoic acid induced 16-like family protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Retinoic acid induced 16-like protein - putative

Species:

Leishmania infantum

UniProt:

A4I2R7_LEIIN

TriTrypDb:

LINF_270018000

Length:

989

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I2R7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I2R7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	180	184	PF00656	0.552
CLV_C14_Caspase3-7	845	849	PF00656	0.456
CLV_NRD_NRD_1	301	303	PF00675	0.504
CLV_NRD_NRD_1	412	414	PF00675	0.510
CLV_NRD_NRD_1	557	559	PF00675	0.505
CLV_NRD_NRD_1	683	685	PF00675	0.623
CLV_NRD_NRD_1	870	872	PF00675	0.610
CLV_NRD_NRD_1	896	898	PF00675	0.490
CLV_PCSK_KEX2_1	412	414	PF00082	0.426
CLV_PCSK_KEX2_1	850	852	PF00082	0.468
CLV_PCSK_KEX2_1	896	898	PF00082	0.592
CLV_PCSK_PC1ET2_1	850	852	PF00082	0.468
CLV_PCSK_SKI1_1	113	117	PF00082	0.582
CLV_PCSK_SKI1_1	194	198	PF00082	0.454
CLV_PCSK_SKI1_1	387	391	PF00082	0.482
CLV_PCSK_SKI1_1	417	421	PF00082	0.394
CLV_PCSK_SKI1_1	550	554	PF00082	0.348
CLV_PCSK_SKI1_1	669	673	PF00082	0.501
CLV_PCSK_SKI1_1	862	866	PF00082	0.466
CLV_PCSK_SKI1_1	871	875	PF00082	0.619
CLV_PCSK_SKI1_1	880	884	PF00082	0.508
DEG_APCC_DBOX_1	386	394	PF00400	0.513
DEG_APCC_DBOX_1	416	424	PF00400	0.410
DEG_APCC_DBOX_1	452	460	PF00400	0.373
DEG_SCF_FBW7_1	928	934	PF00400	0.694
DEG_SCF_TRCP1_1	695	701	PF00400	0.588
DEG_SPOP_SBC_1	318	322	PF00917	0.736
DEG_SPOP_SBC_1	38	42	PF00917	0.734
DEG_SPOP_SBC_1	774	778	PF00917	0.586
DEG_SPOP_SBC_1	890	894	PF00917	0.758
DOC_CDC14_PxL_1	368	376	PF14671	0.382
DOC_CDC14_PxL_1	616	624	PF14671	0.393
DOC_CKS1_1	928	933	PF01111	0.692
DOC_CYCLIN_RxL_1	191	200	PF00134	0.480
DOC_CYCLIN_RxL_1	384	394	PF00134	0.502
DOC_CYCLIN_RxL_1	494	505	PF00134	0.417
DOC_CYCLIN_RxL_1	545	556	PF00134	0.360
DOC_CYCLIN_yClb5_NLxxxL_5	387	393	PF00134	0.425
DOC_MAPK_gen_1	567	575	PF00069	0.357
DOC_MAPK_gen_1	748	758	PF00069	0.564
DOC_MAPK_gen_1	896	903	PF00069	0.519
DOC_MAPK_JIP1_4	289	295	PF00069	0.508
DOC_MAPK_MEF2A_6	289	297	PF00069	0.499
DOC_MAPK_MEF2A_6	896	905	PF00069	0.496
DOC_MAPK_RevD_3	838	851	PF00069	0.455
DOC_PP1_RVXF_1	543	549	PF00149	0.516
DOC_PP2B_LxvP_1	187	190	PF13499	0.546
DOC_PP2B_LxvP_1	293	296	PF13499	0.499
DOC_PP4_FxxP_1	130	133	PF00568	0.695
DOC_PP4_MxPP_1	771	774	PF00568	0.569
DOC_USP7_MATH_1	133	137	PF00917	0.658
DOC_USP7_MATH_1	144	148	PF00917	0.690
DOC_USP7_MATH_1	169	173	PF00917	0.753
DOC_USP7_MATH_1	17	21	PF00917	0.646
DOC_USP7_MATH_1	23	27	PF00917	0.634
DOC_USP7_MATH_1	325	329	PF00917	0.685
DOC_USP7_MATH_1	39	43	PF00917	0.713
DOC_USP7_MATH_1	422	426	PF00917	0.501
DOC_USP7_MATH_1	427	431	PF00917	0.454
DOC_USP7_MATH_1	601	605	PF00917	0.578
DOC_USP7_MATH_1	609	613	PF00917	0.444
DOC_USP7_MATH_1	774	778	PF00917	0.650
DOC_USP7_MATH_1	888	892	PF00917	0.706
DOC_USP7_MATH_1	931	935	PF00917	0.774
DOC_WW_Pin1_4	139	144	PF00397	0.670
DOC_WW_Pin1_4	165	170	PF00397	0.717
DOC_WW_Pin1_4	323	328	PF00397	0.758
DOC_WW_Pin1_4	514	519	PF00397	0.498
DOC_WW_Pin1_4	54	59	PF00397	0.627
DOC_WW_Pin1_4	707	712	PF00397	0.579
DOC_WW_Pin1_4	800	805	PF00397	0.438
DOC_WW_Pin1_4	816	821	PF00397	0.345
DOC_WW_Pin1_4	874	879	PF00397	0.687
DOC_WW_Pin1_4	924	929	PF00397	0.713
LIG_14-3-3_CanoR_1	281	286	PF00244	0.609
LIG_14-3-3_CanoR_1	317	327	PF00244	0.706
LIG_14-3-3_CanoR_1	417	426	PF00244	0.414
LIG_14-3-3_CanoR_1	453	457	PF00244	0.398
LIG_14-3-3_CanoR_1	480	486	PF00244	0.370
LIG_14-3-3_CanoR_1	645	653	PF00244	0.454
LIG_14-3-3_CanoR_1	766	774	PF00244	0.590
LIG_14-3-3_CanoR_1	841	847	PF00244	0.384
LIG_14-3-3_CanoR_1	871	879	PF00244	0.712
LIG_14-3-3_CanoR_1	88	92	PF00244	0.569
LIG_Actin_WH2_2	656	671	PF00022	0.491
LIG_AP2alpha_2	431	433	PF02296	0.507
LIG_BIR_II_1	1	5	PF00653	0.681
LIG_BRCT_BRCA1_1	126	130	PF00533	0.641
LIG_BRCT_BRCA1_1	901	905	PF00533	0.520
LIG_Clathr_ClatBox_1	390	394	PF01394	0.372
LIG_Clathr_ClatBox_1	749	753	PF01394	0.426
LIG_deltaCOP1_diTrp_1	67	76	PF00928	0.405
LIG_DLG_GKlike_1	281	288	PF00625	0.354
LIG_EH1_1	820	828	PF00400	0.491
LIG_eIF4E_1	821	827	PF01652	0.499
LIG_FAT_LD_1	393	401	PF03623	0.329
LIG_FHA_1	327	333	PF00498	0.622
LIG_FHA_1	353	359	PF00498	0.464
LIG_FHA_1	38	44	PF00498	0.627
LIG_FHA_1	452	458	PF00498	0.407
LIG_FHA_1	46	52	PF00498	0.610
LIG_FHA_1	468	474	PF00498	0.414
LIG_FHA_1	493	499	PF00498	0.512
LIG_FHA_1	585	591	PF00498	0.634
LIG_FHA_1	613	619	PF00498	0.457
LIG_FHA_1	650	656	PF00498	0.378
LIG_FHA_1	787	793	PF00498	0.637
LIG_FHA_1	804	810	PF00498	0.446
LIG_FHA_1	874	880	PF00498	0.707
LIG_FHA_1	920	926	PF00498	0.444
LIG_FHA_2	361	367	PF00498	0.457
LIG_FHA_2	656	662	PF00498	0.474
LIG_FHA_2	82	88	PF00498	0.585
LIG_FHA_2	843	849	PF00498	0.397
LIG_GBD_Chelix_1	529	537	PF00786	0.478
LIG_LIR_Apic_2	127	133	PF02991	0.532
LIG_LIR_Apic_2	615	620	PF02991	0.491
LIG_LIR_Gen_1	335	343	PF02991	0.679
LIG_LIR_Gen_1	355	365	PF02991	0.389
LIG_LIR_Gen_1	67	76	PF02991	0.406
LIG_LIR_LC3C_4	829	832	PF02991	0.461
LIG_LIR_Nem_3	335	341	PF02991	0.678
LIG_LIR_Nem_3	355	360	PF02991	0.394
LIG_LIR_Nem_3	611	617	PF02991	0.377
LIG_LIR_Nem_3	67	72	PF02991	0.381
LIG_LIR_Nem_3	74	79	PF02991	0.398
LIG_NRBOX	105	111	PF00104	0.499
LIG_NRBOX	259	265	PF00104	0.474
LIG_NRBOX	388	394	PF00104	0.396
LIG_NRBOX	720	726	PF00104	0.483
LIG_NRBOX	745	751	PF00104	0.430
LIG_NRBOX	842	848	PF00104	0.502
LIG_Pex14_2	130	134	PF04695	0.675
LIG_Rb_pABgroove_1	901	909	PF01858	0.499
LIG_SH2_CRK	193	197	PF00017	0.477
LIG_SH2_CRK	907	911	PF00017	0.479
LIG_SH2_CRK	957	961	PF00017	0.545
LIG_SH2_CRK	975	979	PF00017	0.388
LIG_SH2_PTP2	617	620	PF00017	0.391
LIG_SH2_SRC	964	967	PF00017	0.445
LIG_SH2_SRC	968	971	PF00017	0.394
LIG_SH2_STAP1	571	575	PF00017	0.514
LIG_SH2_STAP1	907	911	PF00017	0.390
LIG_SH2_STAP1	957	961	PF00017	0.484
LIG_SH2_STAT3	243	246	PF00017	0.488
LIG_SH2_STAT5	128	131	PF00017	0.644
LIG_SH2_STAT5	399	402	PF00017	0.435
LIG_SH2_STAT5	474	477	PF00017	0.413
LIG_SH2_STAT5	617	620	PF00017	0.391
LIG_SH2_STAT5	75	78	PF00017	0.392
LIG_SH2_STAT5	821	824	PF00017	0.509
LIG_SH2_STAT5	844	847	PF00017	0.378
LIG_SH2_STAT5	964	967	PF00017	0.494
LIG_SH2_STAT5	968	971	PF00017	0.490
LIG_SH2_STAT5	975	978	PF00017	0.534
LIG_SH2_STAT5	984	987	PF00017	0.362
LIG_SH3_3	137	143	PF00018	0.689
LIG_SH3_3	200	206	PF00018	0.665
LIG_SH3_3	5	11	PF00018	0.540
LIG_SH3_3	572	578	PF00018	0.530
LIG_SH3_3	603	609	PF00018	0.548
LIG_SH3_3	898	904	PF00018	0.559
LIG_SH3_3	925	931	PF00018	0.686
LIG_Sin3_3	828	835	PF02671	0.421
LIG_SUMO_SIM_anti_2	60	67	PF11976	0.421
LIG_SUMO_SIM_anti_2	652	658	PF11976	0.483
LIG_SUMO_SIM_anti_2	833	839	PF11976	0.488
LIG_SUMO_SIM_par_1	388	394	PF11976	0.315
LIG_SUMO_SIM_par_1	652	658	PF11976	0.442
LIG_SUMO_SIM_par_1	897	902	PF11976	0.606
LIG_TRAF2_1	405	408	PF00917	0.527
LIG_TRAF2_1	439	442	PF00917	0.425
LIG_TYR_ITIM	842	847	PF00017	0.487
LIG_TYR_ITIM	955	960	PF00017	0.543
LIG_TYR_ITIM	973	978	PF00017	0.391
LIG_TYR_ITIM	982	987	PF00017	0.580
LIG_UBA3_1	237	245	PF00899	0.399
LIG_UBA3_1	297	303	PF00899	0.432
LIG_UBA3_1	456	461	PF00899	0.412
LIG_UBA3_1	498	504	PF00899	0.523
LIG_UBA3_1	767	772	PF00899	0.643
LIG_UBA3_1	91	100	PF00899	0.590
LIG_UBA3_1	982	986	PF00899	0.530
LIG_WRC_WIRS_1	610	615	PF05994	0.415
LIG_WW_1	190	193	PF00397	0.396
MOD_CDC14_SPxK_1	877	880	PF00782	0.701
MOD_CDK_SPxK_1	874	880	PF00069	0.689
MOD_CDK_SPxxK_3	874	881	PF00069	0.691
MOD_CK1_1	172	178	PF00069	0.678
MOD_CK1_1	326	332	PF00069	0.600
MOD_CK1_1	517	523	PF00069	0.443
MOD_CK1_1	57	63	PF00069	0.501
MOD_CK1_1	612	618	PF00069	0.412
MOD_CK1_1	701	707	PF00069	0.695
MOD_CK1_1	723	729	PF00069	0.625
MOD_CK1_1	776	782	PF00069	0.612
MOD_CK1_1	803	809	PF00069	0.569
MOD_CK1_1	819	825	PF00069	0.399
MOD_CK1_1	886	892	PF00069	0.648
MOD_CK1_1	927	933	PF00069	0.665
MOD_CK1_1	935	941	PF00069	0.478
MOD_CK2_1	139	145	PF00069	0.648
MOD_CK2_1	360	366	PF00069	0.400
MOD_CK2_1	402	408	PF00069	0.509
MOD_CK2_1	601	607	PF00069	0.534
MOD_CK2_1	655	661	PF00069	0.473
MOD_CK2_1	81	87	PF00069	0.579
MOD_CK2_1	933	939	PF00069	0.614
MOD_GlcNHglycan	137	140	PF01048	0.732
MOD_GlcNHglycan	169	172	PF01048	0.635
MOD_GlcNHglycan	18	22	PF01048	0.575
MOD_GlcNHglycan	272	276	PF01048	0.579
MOD_GlcNHglycan	290	293	PF01048	0.528
MOD_GlcNHglycan	323	326	PF01048	0.777
MOD_GlcNHglycan	34	37	PF01048	0.708
MOD_GlcNHglycan	420	423	PF01048	0.522
MOD_GlcNHglycan	523	526	PF01048	0.394
MOD_GlcNHglycan	539	542	PF01048	0.414
MOD_GlcNHglycan	560	563	PF01048	0.505
MOD_GlcNHglycan	582	585	PF01048	0.646
MOD_GlcNHglycan	646	649	PF01048	0.524
MOD_GlcNHglycan	695	698	PF01048	0.613
MOD_GlcNHglycan	700	703	PF01048	0.526
MOD_GlcNHglycan	706	709	PF01048	0.476
MOD_GlcNHglycan	725	728	PF01048	0.473
MOD_GlcNHglycan	768	771	PF01048	0.597
MOD_GlcNHglycan	887	891	PF01048	0.578
MOD_GlcNHglycan	935	938	PF01048	0.688
MOD_GlcNHglycan	939	943	PF01048	0.597
MOD_GSK3_1	135	142	PF00069	0.665
MOD_GSK3_1	160	167	PF00069	0.778
MOD_GSK3_1	169	176	PF00069	0.673
MOD_GSK3_1	23	30	PF00069	0.691
MOD_GSK3_1	316	323	PF00069	0.668
MOD_GSK3_1	326	333	PF00069	0.655
MOD_GSK3_1	398	405	PF00069	0.500
MOD_GSK3_1	418	425	PF00069	0.438
MOD_GSK3_1	451	458	PF00069	0.424
MOD_GSK3_1	484	491	PF00069	0.446
MOD_GSK3_1	517	524	PF00069	0.438
MOD_GSK3_1	580	587	PF00069	0.610
MOD_GSK3_1	608	615	PF00069	0.561
MOD_GSK3_1	640	647	PF00069	0.646
MOD_GSK3_1	719	726	PF00069	0.603
MOD_GSK3_1	773	780	PF00069	0.714
MOD_GSK3_1	799	806	PF00069	0.519
MOD_GSK3_1	815	822	PF00069	0.300
MOD_GSK3_1	842	849	PF00069	0.452
MOD_GSK3_1	886	893	PF00069	0.743
MOD_GSK3_1	927	934	PF00069	0.719
MOD_N-GLC_1	931	936	PF02516	0.658
MOD_NEK2_1	115	120	PF00069	0.568
MOD_NEK2_1	173	178	PF00069	0.686
MOD_NEK2_1	197	202	PF00069	0.553
MOD_NEK2_1	27	32	PF00069	0.672
MOD_NEK2_1	360	365	PF00069	0.396
MOD_NEK2_1	418	423	PF00069	0.518
MOD_NEK2_1	481	486	PF00069	0.449
MOD_NEK2_1	537	542	PF00069	0.410
MOD_NEK2_1	552	557	PF00069	0.353
MOD_NEK2_1	590	595	PF00069	0.590
MOD_NEK2_1	639	644	PF00069	0.630
MOD_NEK2_1	655	660	PF00069	0.258
MOD_NEK2_1	720	725	PF00069	0.590
MOD_NEK2_1	830	835	PF00069	0.357
MOD_NEK2_1	846	851	PF00069	0.417
MOD_NEK2_1	899	904	PF00069	0.499
MOD_NEK2_2	609	614	PF00069	0.481
MOD_PIKK_1	352	358	PF00454	0.473
MOD_PIKK_1	381	387	PF00454	0.608
MOD_PIKK_1	403	409	PF00454	0.565
MOD_PIKK_1	467	473	PF00454	0.470
MOD_PIKK_1	976	982	PF00454	0.536
MOD_PK_1	100	106	PF00069	0.426
MOD_PKA_1	302	308	PF00069	0.516
MOD_PKA_1	412	418	PF00069	0.441
MOD_PKA_1	558	564	PF00069	0.510
MOD_PKA_1	871	877	PF00069	0.577
MOD_PKA_1	880	886	PF00069	0.533
MOD_PKA_2	152	158	PF00069	0.779
MOD_PKA_2	288	294	PF00069	0.452
MOD_PKA_2	316	322	PF00069	0.760
MOD_PKA_2	412	418	PF00069	0.441
MOD_PKA_2	452	458	PF00069	0.375
MOD_PKA_2	644	650	PF00069	0.484
MOD_PKA_2	87	93	PF00069	0.577
MOD_Plk_1	144	150	PF00069	0.564
MOD_Plk_1	271	277	PF00069	0.631
MOD_Plk_1	633	639	PF00069	0.674
MOD_Plk_1	86	92	PF00069	0.568
MOD_Plk_2-3	675	681	PF00069	0.576
MOD_Plk_2-3	94	100	PF00069	0.532
MOD_Plk_4	100	106	PF00069	0.426
MOD_Plk_4	124	130	PF00069	0.728
MOD_Plk_4	281	287	PF00069	0.438
MOD_Plk_4	344	350	PF00069	0.546
MOD_Plk_4	452	458	PF00069	0.442
MOD_Plk_4	481	487	PF00069	0.373
MOD_Plk_4	507	513	PF00069	0.384
MOD_Plk_4	57	63	PF00069	0.474
MOD_Plk_4	609	615	PF00069	0.371
MOD_Plk_4	634	640	PF00069	0.668
MOD_Plk_4	649	655	PF00069	0.311
MOD_Plk_4	720	726	PF00069	0.496
MOD_Plk_4	822	828	PF00069	0.354
MOD_Plk_4	842	848	PF00069	0.379
MOD_Plk_4	87	93	PF00069	0.626
MOD_ProDKin_1	139	145	PF00069	0.674
MOD_ProDKin_1	165	171	PF00069	0.713
MOD_ProDKin_1	323	329	PF00069	0.750
MOD_ProDKin_1	514	520	PF00069	0.503
MOD_ProDKin_1	54	60	PF00069	0.611
MOD_ProDKin_1	707	713	PF00069	0.579
MOD_ProDKin_1	800	806	PF00069	0.433
MOD_ProDKin_1	816	822	PF00069	0.348
MOD_ProDKin_1	874	880	PF00069	0.689
MOD_ProDKin_1	924	930	PF00069	0.714
MOD_SUMO_for_1	439	442	PF00179	0.425
MOD_SUMO_rev_2	629	635	PF00179	0.631
TRG_DiLeu_BaEn_1	386	391	PF01217	0.449
TRG_DiLeu_BaEn_1	634	639	PF01217	0.629
TRG_DiLeu_BaEn_1	87	92	PF01217	0.571
TRG_DiLeu_BaLyEn_6	259	264	PF01217	0.378
TRG_DiLeu_BaLyEn_6	293	298	PF01217	0.397
TRG_DiLeu_BaLyEn_6	494	499	PF01217	0.557
TRG_DiLeu_BaLyEn_6	510	515	PF01217	0.344
TRG_DiLeu_BaLyEn_6	539	544	PF01217	0.491
TRG_DiLeu_BaLyEn_6	745	750	PF01217	0.427
TRG_ENDOCYTIC_2	193	196	PF00928	0.388
TRG_ENDOCYTIC_2	571	574	PF00928	0.507
TRG_ENDOCYTIC_2	616	619	PF00928	0.365
TRG_ENDOCYTIC_2	844	847	PF00928	0.378
TRG_ENDOCYTIC_2	907	910	PF00928	0.371
TRG_ENDOCYTIC_2	957	960	PF00928	0.545
TRG_ENDOCYTIC_2	975	978	PF00928	0.390
TRG_ENDOCYTIC_2	984	987	PF00928	0.592
TRG_ER_diArg_1	896	898	PF00400	0.490
TRG_NES_CRM1_1	94	107	PF08389	0.513
TRG_Pf-PMV_PEXEL_1	194	199	PF00026	0.475
TRG_Pf-PMV_PEXEL_1	262	266	PF00026	0.404
TRG_Pf-PMV_PEXEL_1	49	54	PF00026	0.651
TRG_Pf-PMV_PEXEL_1	748	753	PF00026	0.442

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6X3	Leptomonas seymouri	52%	90%
A0A1X0P440	Trypanosomatidae	31%	96%
A0A3S5H7H7	Leishmania donovani	99%	100%
A0A3S5IQJ7	Trypanosoma rangeli	29%	100%
A4HFP1	Leishmania braziliensis	76%	99%
E9AD94	Leishmania major	92%	100%
E9AZ19	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
V5BHP8	Trypanosoma cruzi	30%	100%