LeishMANIAdb
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ATP-binding cassette protein subfamily A, member 8

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
ATP-binding cassette protein subfamily A, member 8
Gene product:
ATP-binding cassette subfamily A - member 1 - putative
Species:
Leishmania infantum
UniProt:
A4I2P8_LEIIN
TriTrypDb:
LINF_270016000
Length:
1843

Annotations

Annotations by Jardim et al.

Transporters, ATP-binding cassette A, member 8 ABCA8

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) yes yes: 3
Silverman et al. no yes: 0
Pissara et al. yes yes: 20
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 6
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 44
NetGPI no yes: 0, no: 44
Cellular components
Term Name Level Count
GO:0016020 membrane 2 45
GO:0110165 cellular anatomical entity 1 45
GO:0043226 organelle 2 7
GO:0043227 membrane-bounded organelle 3 7
GO:0043229 intracellular organelle 3 7
GO:0043231 intracellular membrane-bounded organelle 4 7

Expansion

Sequence features

A4I2P8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I2P8

Function

Biological processes
Term Name Level Count
GO:0006810 transport 3 7
GO:0006869 lipid transport 5 7
GO:0051179 localization 1 7
GO:0051234 establishment of localization 2 7
GO:0071702 organic substance transport 4 7
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 45
GO:0005215 transporter activity 1 45
GO:0005488 binding 1 45
GO:0005524 ATP binding 5 45
GO:0015399 primary active transmembrane transporter activity 4 45
GO:0017076 purine nucleotide binding 4 45
GO:0022804 active transmembrane transporter activity 3 45
GO:0022857 transmembrane transporter activity 2 45
GO:0030554 adenyl nucleotide binding 5 45
GO:0032553 ribonucleotide binding 3 45
GO:0032555 purine ribonucleotide binding 4 45
GO:0032559 adenyl ribonucleotide binding 5 45
GO:0035639 purine ribonucleoside triphosphate binding 4 45
GO:0036094 small molecule binding 2 45
GO:0042626 ATPase-coupled transmembrane transporter activity 2 45
GO:0043167 ion binding 2 45
GO:0043168 anion binding 3 45
GO:0097159 organic cyclic compound binding 2 45
GO:0097367 carbohydrate derivative binding 2 45
GO:0140359 ABC-type transporter activity 3 45
GO:0140657 ATP-dependent activity 1 45
GO:1901265 nucleoside phosphate binding 3 45
GO:1901363 heterocyclic compound binding 2 45
GO:0003824 catalytic activity 1 1
GO:0016787 hydrolase activity 2 1
GO:0005319 lipid transporter activity 2 7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1029 1033 PF00656 0.581
CLV_C14_Caspase3-7 104 108 PF00656 0.764
CLV_C14_Caspase3-7 1154 1158 PF00656 0.239
CLV_C14_Caspase3-7 1220 1224 PF00656 0.239
CLV_C14_Caspase3-7 1681 1685 PF00656 0.590
CLV_C14_Caspase3-7 343 347 PF00656 0.367
CLV_NRD_NRD_1 1065 1067 PF00675 0.435
CLV_NRD_NRD_1 1084 1086 PF00675 0.308
CLV_NRD_NRD_1 132 134 PF00675 0.579
CLV_NRD_NRD_1 1462 1464 PF00675 0.413
CLV_NRD_NRD_1 1491 1493 PF00675 0.420
CLV_NRD_NRD_1 1510 1512 PF00675 0.358
CLV_NRD_NRD_1 1630 1632 PF00675 0.324
CLV_NRD_NRD_1 1642 1644 PF00675 0.312
CLV_NRD_NRD_1 1672 1674 PF00675 0.391
CLV_NRD_NRD_1 683 685 PF00675 0.474
CLV_NRD_NRD_1 723 725 PF00675 0.367
CLV_NRD_NRD_1 728 730 PF00675 0.437
CLV_NRD_NRD_1 834 836 PF00675 0.385
CLV_NRD_NRD_1 858 860 PF00675 0.326
CLV_NRD_NRD_1 888 890 PF00675 0.396
CLV_NRD_NRD_1 957 959 PF00675 0.362
CLV_PCSK_FUR_1 1082 1086 PF00082 0.353
CLV_PCSK_KEX2_1 1064 1066 PF00082 0.405
CLV_PCSK_KEX2_1 1075 1077 PF00082 0.356
CLV_PCSK_KEX2_1 1084 1086 PF00082 0.304
CLV_PCSK_KEX2_1 132 134 PF00082 0.616
CLV_PCSK_KEX2_1 1462 1464 PF00082 0.424
CLV_PCSK_KEX2_1 1491 1493 PF00082 0.417
CLV_PCSK_KEX2_1 1630 1632 PF00082 0.321
CLV_PCSK_KEX2_1 1642 1644 PF00082 0.314
CLV_PCSK_KEX2_1 165 167 PF00082 0.397
CLV_PCSK_KEX2_1 1672 1674 PF00082 0.391
CLV_PCSK_KEX2_1 478 480 PF00082 0.355
CLV_PCSK_KEX2_1 682 684 PF00082 0.481
CLV_PCSK_KEX2_1 728 730 PF00082 0.468
CLV_PCSK_KEX2_1 834 836 PF00082 0.384
CLV_PCSK_KEX2_1 858 860 PF00082 0.320
CLV_PCSK_KEX2_1 888 890 PF00082 0.396
CLV_PCSK_KEX2_1 957 959 PF00082 0.514
CLV_PCSK_PC1ET2_1 1075 1077 PF00082 0.356
CLV_PCSK_PC1ET2_1 165 167 PF00082 0.390
CLV_PCSK_PC1ET2_1 478 480 PF00082 0.355
CLV_PCSK_PC1ET2_1 858 860 PF00082 0.313
CLV_PCSK_PC7_1 1061 1067 PF00082 0.316
CLV_PCSK_PC7_1 724 730 PF00082 0.397
CLV_PCSK_SKI1_1 1217 1221 PF00082 0.477
CLV_PCSK_SKI1_1 1397 1401 PF00082 0.550
CLV_PCSK_SKI1_1 1492 1496 PF00082 0.498
CLV_PCSK_SKI1_1 1656 1660 PF00082 0.290
CLV_PCSK_SKI1_1 432 436 PF00082 0.604
CLV_PCSK_SKI1_1 834 838 PF00082 0.306
CLV_PCSK_SKI1_1 991 995 PF00082 0.448
DEG_APCC_DBOX_1 785 793 PF00400 0.503
DEG_APCC_DBOX_1 833 841 PF00400 0.598
DEG_ODPH_VHL_1 569 581 PF01847 0.493
DEG_SCF_FBW7_1 1139 1145 PF00400 0.239
DEG_SCF_FBW7_2 235 240 PF00400 0.234
DEG_SCF_FBW7_2 314 320 PF00400 0.239
DEG_SPOP_SBC_1 11 15 PF00917 0.640
DEG_SPOP_SBC_1 274 278 PF00917 0.247
DOC_CKS1_1 1110 1115 PF01111 0.373
DOC_CKS1_1 1139 1144 PF01111 0.247
DOC_CKS1_1 314 319 PF01111 0.431
DOC_CKS1_1 48 53 PF01111 0.624
DOC_CYCLIN_RxL_1 1500 1513 PF00134 0.507
DOC_CYCLIN_RxL_1 155 167 PF00134 0.623
DOC_CYCLIN_RxL_1 829 841 PF00134 0.446
DOC_CYCLIN_yClb1_LxF_4 666 672 PF00134 0.524
DOC_CYCLIN_yClb5_NLxxxL_5 1390 1396 PF00134 0.220
DOC_CYCLIN_yCln2_LP_2 968 974 PF00134 0.528
DOC_MAPK_FxFP_2 469 472 PF00069 0.375
DOC_MAPK_gen_1 1061 1069 PF00069 0.688
DOC_MAPK_gen_1 1615 1623 PF00069 0.552
DOC_MAPK_gen_1 1642 1651 PF00069 0.516
DOC_MAPK_gen_1 484 494 PF00069 0.539
DOC_MAPK_gen_1 834 842 PF00069 0.558
DOC_MAPK_gen_1 858 867 PF00069 0.523
DOC_MAPK_gen_1 939 946 PF00069 0.512
DOC_MAPK_MEF2A_6 1108 1117 PF00069 0.343
DOC_MAPK_MEF2A_6 1642 1651 PF00069 0.516
DOC_MAPK_MEF2A_6 628 637 PF00069 0.347
DOC_MAPK_MEF2A_6 858 867 PF00069 0.517
DOC_MAPK_MEF2A_6 939 946 PF00069 0.512
DOC_MAPK_RevD_3 874 889 PF00069 0.584
DOC_PP1_RVXF_1 1063 1070 PF00149 0.622
DOC_PP1_RVXF_1 1392 1399 PF00149 0.352
DOC_PP1_RVXF_1 1654 1661 PF00149 0.523
DOC_PP2B_PxIxI_1 461 467 PF00149 0.448
DOC_PP4_FxxP_1 1110 1113 PF00568 0.326
DOC_PP4_FxxP_1 1470 1473 PF00568 0.676
DOC_PP4_FxxP_1 1660 1663 PF00568 0.444
DOC_PP4_FxxP_1 175 178 PF00568 0.395
DOC_PP4_FxxP_1 24 27 PF00568 0.634
DOC_PP4_FxxP_1 469 472 PF00568 0.393
DOC_USP7_MATH_1 1156 1160 PF00917 0.377
DOC_USP7_MATH_1 1184 1188 PF00917 0.420
DOC_USP7_MATH_1 1230 1234 PF00917 0.340
DOC_USP7_MATH_1 1235 1239 PF00917 0.326
DOC_USP7_MATH_1 1242 1246 PF00917 0.318
DOC_USP7_MATH_1 195 199 PF00917 0.352
DOC_USP7_MATH_1 387 391 PF00917 0.326
DOC_USP7_MATH_1 758 762 PF00917 0.472
DOC_USP7_MATH_1 922 926 PF00917 0.565
DOC_USP7_MATH_1 96 100 PF00917 0.651
DOC_USP7_MATH_1 974 978 PF00917 0.746
DOC_USP7_MATH_1 987 991 PF00917 0.679
DOC_USP7_UBL2_3 1719 1723 PF12436 0.619
DOC_USP7_UBL2_3 432 436 PF12436 0.381
DOC_USP7_UBL2_3 896 900 PF12436 0.560
DOC_WW_Pin1_4 1109 1114 PF00397 0.333
DOC_WW_Pin1_4 1138 1143 PF00397 0.331
DOC_WW_Pin1_4 136 141 PF00397 0.651
DOC_WW_Pin1_4 1737 1742 PF00397 0.554
DOC_WW_Pin1_4 23 28 PF00397 0.827
DOC_WW_Pin1_4 233 238 PF00397 0.361
DOC_WW_Pin1_4 275 280 PF00397 0.386
DOC_WW_Pin1_4 299 304 PF00397 0.292
DOC_WW_Pin1_4 313 318 PF00397 0.246
DOC_WW_Pin1_4 404 409 PF00397 0.247
DOC_WW_Pin1_4 47 52 PF00397 0.785
DOC_WW_Pin1_4 531 536 PF00397 0.239
DOC_WW_Pin1_4 55 60 PF00397 0.818
DOC_WW_Pin1_4 7 12 PF00397 0.664
DOC_WW_Pin1_4 94 99 PF00397 0.817
LIG_14-3-3_CanoR_1 1084 1092 PF00244 0.542
LIG_14-3-3_CanoR_1 1108 1113 PF00244 0.253
LIG_14-3-3_CanoR_1 1167 1177 PF00244 0.266
LIG_14-3-3_CanoR_1 132 140 PF00244 0.787
LIG_14-3-3_CanoR_1 1462 1470 PF00244 0.645
LIG_14-3-3_CanoR_1 1642 1648 PF00244 0.513
LIG_14-3-3_CanoR_1 1767 1771 PF00244 0.561
LIG_14-3-3_CanoR_1 1777 1782 PF00244 0.565
LIG_14-3-3_CanoR_1 1810 1817 PF00244 0.681
LIG_14-3-3_CanoR_1 299 303 PF00244 0.431
LIG_14-3-3_CanoR_1 526 530 PF00244 0.421
LIG_14-3-3_CanoR_1 724 728 PF00244 0.623
LIG_14-3-3_CanoR_1 859 864 PF00244 0.504
LIG_14-3-3_CanoR_1 86 91 PF00244 0.773
LIG_14-3-3_CanoR_1 888 893 PF00244 0.608
LIG_Actin_WH2_2 1370 1388 PF00022 0.247
LIG_Actin_WH2_2 1405 1421 PF00022 0.247
LIG_Actin_WH2_2 1698 1716 PF00022 0.579
LIG_Actin_WH2_2 512 528 PF00022 0.378
LIG_AP2alpha_1 641 645 PF02296 0.261
LIG_APCC_ABBA_1 1453 1458 PF00400 0.395
LIG_APCC_ABBA_1 1747 1752 PF00400 0.506
LIG_APCC_ABBA_1 638 643 PF00400 0.403
LIG_APCC_ABBA_1 650 655 PF00400 0.357
LIG_BRCT_BRCA1_1 1351 1355 PF00533 0.386
LIG_BRCT_BRCA1_1 1778 1782 PF00533 0.569
LIG_BRCT_BRCA1_1 300 304 PF00533 0.381
LIG_BRCT_BRCA1_1 329 333 PF00533 0.337
LIG_BRCT_BRCA1_1 39 43 PF00533 0.633
LIG_BRCT_BRCA1_1 933 937 PF00533 0.573
LIG_BRCT_BRCA1_2 933 939 PF00533 0.572
LIG_Clathr_ClatBox_1 1592 1596 PF01394 0.538
LIG_Clathr_ClatBox_1 581 585 PF01394 0.390
LIG_Clathr_ClatBox_1 639 643 PF01394 0.403
LIG_Clathr_ClatBox_1 873 877 PF01394 0.512
LIG_deltaCOP1_diTrp_1 167 175 PF00928 0.589
LIG_deltaCOP1_diTrp_1 499 506 PF00928 0.447
LIG_EH1_1 1339 1347 PF00400 0.269
LIG_EH1_1 1702 1710 PF00400 0.569
LIG_EH1_1 374 382 PF00400 0.247
LIG_EH1_1 513 521 PF00400 0.305
LIG_FHA_1 1047 1053 PF00498 0.642
LIG_FHA_1 1110 1116 PF00498 0.356
LIG_FHA_1 1196 1202 PF00498 0.352
LIG_FHA_1 1206 1212 PF00498 0.375
LIG_FHA_1 1226 1232 PF00498 0.333
LIG_FHA_1 1306 1312 PF00498 0.366
LIG_FHA_1 1331 1337 PF00498 0.371
LIG_FHA_1 1387 1393 PF00498 0.337
LIG_FHA_1 1452 1458 PF00498 0.429
LIG_FHA_1 1543 1549 PF00498 0.525
LIG_FHA_1 1690 1696 PF00498 0.569
LIG_FHA_1 1767 1773 PF00498 0.569
LIG_FHA_1 213 219 PF00498 0.363
LIG_FHA_1 234 240 PF00498 0.420
LIG_FHA_1 314 320 PF00498 0.333
LIG_FHA_1 346 352 PF00498 0.358
LIG_FHA_1 359 365 PF00498 0.430
LIG_FHA_1 372 378 PF00498 0.344
LIG_FHA_1 424 430 PF00498 0.292
LIG_FHA_1 433 439 PF00498 0.275
LIG_FHA_1 475 481 PF00498 0.407
LIG_FHA_1 48 54 PF00498 0.634
LIG_FHA_1 499 505 PF00498 0.544
LIG_FHA_1 520 526 PF00498 0.370
LIG_FHA_1 547 553 PF00498 0.348
LIG_FHA_1 761 767 PF00498 0.544
LIG_FHA_1 889 895 PF00498 0.588
LIG_FHA_1 901 907 PF00498 0.531
LIG_FHA_1 918 924 PF00498 0.577
LIG_FHA_1 947 953 PF00498 0.607
LIG_FHA_2 1016 1022 PF00498 0.579
LIG_FHA_2 1122 1128 PF00498 0.330
LIG_FHA_2 1218 1224 PF00498 0.260
LIG_FHA_2 1592 1598 PF00498 0.522
LIG_FHA_2 1679 1685 PF00498 0.630
LIG_FHA_2 169 175 PF00498 0.545
LIG_FHA_2 1726 1732 PF00498 0.684
LIG_FHA_2 1781 1787 PF00498 0.506
LIG_FHA_2 1800 1806 PF00498 0.603
LIG_FHA_2 204 210 PF00498 0.418
LIG_FHA_2 341 347 PF00498 0.345
LIG_FHA_2 353 359 PF00498 0.333
LIG_FHA_2 808 814 PF00498 0.518
LIG_FHA_2 86 92 PF00498 0.638
LIG_GBD_Chelix_1 1095 1103 PF00786 0.429
LIG_GBD_Chelix_1 1367 1375 PF00786 0.431
LIG_GBD_Chelix_1 265 273 PF00786 0.468
LIG_GBD_Chelix_1 516 524 PF00786 0.367
LIG_HCF-1_HBM_1 1597 1600 PF13415 0.444
LIG_LIR_Apic_2 174 178 PF02991 0.430
LIG_LIR_Apic_2 1769 1773 PF02991 0.580
LIG_LIR_Apic_2 981 987 PF02991 0.587
LIG_LIR_Gen_1 1021 1031 PF02991 0.606
LIG_LIR_Gen_1 1086 1096 PF02991 0.443
LIG_LIR_Gen_1 1150 1160 PF02991 0.395
LIG_LIR_Gen_1 1189 1196 PF02991 0.349
LIG_LIR_Gen_1 124 135 PF02991 0.599
LIG_LIR_Gen_1 1245 1256 PF02991 0.408
LIG_LIR_Gen_1 1322 1332 PF02991 0.383
LIG_LIR_Gen_1 1333 1342 PF02991 0.439
LIG_LIR_Gen_1 1779 1786 PF02991 0.567
LIG_LIR_Gen_1 1805 1815 PF02991 0.603
LIG_LIR_Gen_1 412 422 PF02991 0.332
LIG_LIR_Gen_1 439 448 PF02991 0.363
LIG_LIR_Gen_1 534 545 PF02991 0.347
LIG_LIR_Gen_1 546 555 PF02991 0.334
LIG_LIR_Gen_1 643 653 PF02991 0.377
LIG_LIR_Gen_1 702 712 PF02991 0.705
LIG_LIR_Gen_1 816 824 PF02991 0.557
LIG_LIR_Gen_1 891 899 PF02991 0.573
LIG_LIR_Nem_3 1021 1027 PF02991 0.581
LIG_LIR_Nem_3 1086 1092 PF02991 0.431
LIG_LIR_Nem_3 1150 1155 PF02991 0.289
LIG_LIR_Nem_3 1175 1180 PF02991 0.375
LIG_LIR_Nem_3 1189 1194 PF02991 0.385
LIG_LIR_Nem_3 124 130 PF02991 0.786
LIG_LIR_Nem_3 1289 1293 PF02991 0.597
LIG_LIR_Nem_3 1322 1327 PF02991 0.374
LIG_LIR_Nem_3 1333 1337 PF02991 0.372
LIG_LIR_Nem_3 1532 1537 PF02991 0.520
LIG_LIR_Nem_3 1779 1785 PF02991 0.570
LIG_LIR_Nem_3 1805 1811 PF02991 0.593
LIG_LIR_Nem_3 305 309 PF02991 0.359
LIG_LIR_Nem_3 361 365 PF02991 0.311
LIG_LIR_Nem_3 412 417 PF02991 0.326
LIG_LIR_Nem_3 419 425 PF02991 0.339
LIG_LIR_Nem_3 498 503 PF02991 0.543
LIG_LIR_Nem_3 534 540 PF02991 0.325
LIG_LIR_Nem_3 546 550 PF02991 0.331
LIG_LIR_Nem_3 643 648 PF02991 0.372
LIG_LIR_Nem_3 702 708 PF02991 0.700
LIG_LIR_Nem_3 816 821 PF02991 0.554
LIG_LIR_Nem_3 891 895 PF02991 0.590
LIG_NRBOX 1099 1105 PF00104 0.354
LIG_PAM2_1 598 610 PF00658 0.242
LIG_PCNA_PIPBox_1 418 427 PF02747 0.349
LIG_PCNA_PIPBox_1 808 817 PF02747 0.439
LIG_PCNA_yPIPBox_3 1801 1814 PF02747 0.575
LIG_Pex14_1 1294 1298 PF04695 0.368
LIG_Pex14_1 1438 1442 PF04695 0.421
LIG_Pex14_1 506 510 PF04695 0.416
LIG_Pex14_2 1290 1294 PF04695 0.523
LIG_Pex14_2 1370 1374 PF04695 0.387
LIG_Pex14_2 1452 1456 PF04695 0.464
LIG_Pex14_2 1751 1755 PF04695 0.614
LIG_Pex14_2 603 607 PF04695 0.410
LIG_Pex14_2 637 641 PF04695 0.410
LIG_PTB_Apo_2 1294 1301 PF02174 0.392
LIG_PTB_Apo_2 664 671 PF02174 0.533
LIG_Rb_LxCxE_1 1545 1559 PF01857 0.507
LIG_SH2_CRK 1177 1181 PF00017 0.341
LIG_SH2_CRK 1191 1195 PF00017 0.386
LIG_SH2_CRK 127 131 PF00017 0.554
LIG_SH2_CRK 1602 1606 PF00017 0.510
LIG_SH2_CRK 1770 1774 PF00017 0.615
LIG_SH2_CRK 258 262 PF00017 0.427
LIG_SH2_CRK 306 310 PF00017 0.284
LIG_SH2_CRK 414 418 PF00017 0.402
LIG_SH2_CRK 514 518 PF00017 0.493
LIG_SH2_CRK 818 822 PF00017 0.560
LIG_SH2_CRK 984 988 PF00017 0.591
LIG_SH2_NCK_1 514 518 PF00017 0.493
LIG_SH2_PTP2 1324 1327 PF00017 0.334
LIG_SH2_SRC 1600 1603 PF00017 0.444
LIG_SH2_SRC 258 261 PF00017 0.383
LIG_SH2_SRC 779 782 PF00017 0.541
LIG_SH2_STAP1 1013 1017 PF00017 0.620
LIG_SH2_STAP1 1248 1252 PF00017 0.408
LIG_SH2_STAP1 1349 1353 PF00017 0.419
LIG_SH2_STAP1 425 429 PF00017 0.347
LIG_SH2_STAT3 1582 1585 PF00017 0.534
LIG_SH2_STAT5 1291 1294 PF00017 0.590
LIG_SH2_STAT5 1305 1308 PF00017 0.399
LIG_SH2_STAT5 1324 1327 PF00017 0.228
LIG_SH2_STAT5 1406 1409 PF00017 0.320
LIG_SH2_STAT5 1563 1566 PF00017 0.566
LIG_SH2_STAT5 1582 1585 PF00017 0.485
LIG_SH2_STAT5 1600 1603 PF00017 0.540
LIG_SH2_STAT5 245 248 PF00017 0.267
LIG_SH2_STAT5 311 314 PF00017 0.361
LIG_SH2_STAT5 370 373 PF00017 0.366
LIG_SH2_STAT5 397 400 PF00017 0.337
LIG_SH2_STAT5 409 412 PF00017 0.310
LIG_SH2_STAT5 414 417 PF00017 0.309
LIG_SH2_STAT5 425 428 PF00017 0.337
LIG_SH2_STAT5 440 443 PF00017 0.193
LIG_SH2_STAT5 503 506 PF00017 0.427
LIG_SH2_STAT5 514 517 PF00017 0.388
LIG_SH2_STAT5 529 532 PF00017 0.348
LIG_SH2_STAT5 537 540 PF00017 0.394
LIG_SH2_STAT5 574 577 PF00017 0.365
LIG_SH2_STAT5 626 629 PF00017 0.384
LIG_SH2_STAT5 647 650 PF00017 0.350
LIG_SH2_STAT5 653 656 PF00017 0.420
LIG_SH2_STAT5 779 782 PF00017 0.540
LIG_SH3_1 311 317 PF00018 0.381
LIG_SH3_3 1123 1129 PF00018 0.247
LIG_SH3_3 1136 1142 PF00018 0.271
LIG_SH3_3 276 282 PF00018 0.370
LIG_SH3_3 3 9 PF00018 0.674
LIG_SH3_3 311 317 PF00018 0.344
LIG_SH3_3 669 675 PF00018 0.583
LIG_SH3_3 989 995 PF00018 0.610
LIG_SH3_4 432 439 PF00018 0.239
LIG_SUMO_SIM_anti_2 1545 1552 PF11976 0.507
LIG_SUMO_SIM_anti_2 515 522 PF11976 0.422
LIG_SUMO_SIM_anti_2 748 753 PF11976 0.524
LIG_SUMO_SIM_anti_2 871 878 PF11976 0.498
LIG_SUMO_SIM_anti_2 919 925 PF11976 0.603
LIG_SUMO_SIM_par_1 1111 1120 PF11976 0.292
LIG_SUMO_SIM_par_1 1134 1141 PF11976 0.259
LIG_SUMO_SIM_par_1 1376 1381 PF11976 0.417
LIG_SUMO_SIM_par_1 1591 1597 PF11976 0.542
LIG_SUMO_SIM_par_1 348 355 PF11976 0.423
LIG_SUMO_SIM_par_1 363 369 PF11976 0.360
LIG_SUMO_SIM_par_1 548 553 PF11976 0.408
LIG_SUMO_SIM_par_1 871 878 PF11976 0.498
LIG_SUMO_SIM_par_1 902 908 PF11976 0.537
LIG_SUMO_SIM_par_1 919 925 PF11976 0.564
LIG_TRAF2_1 1000 1003 PF00917 0.684
LIG_TRAF2_1 1019 1022 PF00917 0.604
LIG_TRAF2_1 1594 1597 PF00917 0.518
LIG_TRAF2_1 711 714 PF00917 0.670
LIG_TYR_ITIM 512 517 PF00017 0.470
LIG_UBA3_1 157 165 PF00899 0.530
LIG_UBA3_1 894 900 PF00899 0.485
LIG_Vh1_VBS_1 1378 1396 PF01044 0.476
MOD_CDC14_SPxK_1 139 142 PF00782 0.486
MOD_CDK_SPxK_1 136 142 PF00069 0.654
MOD_CK1_1 10 16 PF00069 0.570
MOD_CK1_1 1016 1022 PF00069 0.442
MOD_CK1_1 1111 1117 PF00069 0.405
MOD_CK1_1 1159 1165 PF00069 0.438
MOD_CK1_1 1226 1232 PF00069 0.450
MOD_CK1_1 1286 1292 PF00069 0.473
MOD_CK1_1 136 142 PF00069 0.773
MOD_CK1_1 1381 1387 PF00069 0.404
MOD_CK1_1 1758 1764 PF00069 0.620
MOD_CK1_1 1780 1786 PF00069 0.542
MOD_CK1_1 1800 1806 PF00069 0.483
MOD_CK1_1 1829 1835 PF00069 0.677
MOD_CK1_1 212 218 PF00069 0.498
MOD_CK1_1 227 233 PF00069 0.454
MOD_CK1_1 321 327 PF00069 0.408
MOD_CK1_1 392 398 PF00069 0.391
MOD_CK1_1 404 410 PF00069 0.414
MOD_CK1_1 412 418 PF00069 0.401
MOD_CK1_1 474 480 PF00069 0.427
MOD_CK1_1 498 504 PF00069 0.325
MOD_CK1_1 546 552 PF00069 0.368
MOD_CK1_1 58 64 PF00069 0.562
MOD_CK1_1 951 957 PF00069 0.491
MOD_CK2_1 1015 1021 PF00069 0.458
MOD_CK2_1 106 112 PF00069 0.538
MOD_CK2_1 1381 1387 PF00069 0.420
MOD_CK2_1 1591 1597 PF00069 0.367
MOD_CK2_1 168 174 PF00069 0.396
MOD_CK2_1 1725 1731 PF00069 0.504
MOD_CK2_1 1780 1786 PF00069 0.447
MOD_CK2_1 1799 1805 PF00069 0.473
MOD_CK2_1 203 209 PF00069 0.247
MOD_CK2_1 740 746 PF00069 0.403
MOD_CK2_1 807 813 PF00069 0.336
MOD_CK2_1 824 830 PF00069 0.360
MOD_CK2_1 85 91 PF00069 0.726
MOD_CK2_1 96 102 PF00069 0.805
MOD_Cter_Amidation 1460 1463 PF01082 0.560
MOD_DYRK1A_RPxSP_1 299 303 PF00069 0.257
MOD_GlcNHglycan 1015 1018 PF01048 0.465
MOD_GlcNHglycan 1157 1161 PF01048 0.426
MOD_GlcNHglycan 1186 1189 PF01048 0.400
MOD_GlcNHglycan 1198 1201 PF01048 0.354
MOD_GlcNHglycan 1285 1288 PF01048 0.373
MOD_GlcNHglycan 133 136 PF01048 0.744
MOD_GlcNHglycan 1342 1345 PF01048 0.381
MOD_GlcNHglycan 1380 1383 PF01048 0.441
MOD_GlcNHglycan 1558 1561 PF01048 0.393
MOD_GlcNHglycan 1636 1640 PF01048 0.371
MOD_GlcNHglycan 1661 1666 PF01048 0.379
MOD_GlcNHglycan 197 200 PF01048 0.415
MOD_GlcNHglycan 211 214 PF01048 0.480
MOD_GlcNHglycan 229 232 PF01048 0.392
MOD_GlcNHglycan 383 386 PF01048 0.467
MOD_GlcNHglycan 394 397 PF01048 0.364
MOD_GlcNHglycan 411 414 PF01048 0.321
MOD_GlcNHglycan 552 555 PF01048 0.406
MOD_GlcNHglycan 587 590 PF01048 0.356
MOD_GlcNHglycan 60 63 PF01048 0.536
MOD_GlcNHglycan 600 603 PF01048 0.368
MOD_GlcNHglycan 64 67 PF01048 0.766
MOD_GlcNHglycan 788 792 PF01048 0.457
MOD_GlcNHglycan 853 856 PF01048 0.372
MOD_GlcNHglycan 976 979 PF01048 0.535
MOD_GlcNHglycan 98 101 PF01048 0.678
MOD_GSK3_1 1011 1018 PF00069 0.477
MOD_GSK3_1 1111 1118 PF00069 0.369
MOD_GSK3_1 1137 1144 PF00069 0.390
MOD_GSK3_1 1156 1163 PF00069 0.349
MOD_GSK3_1 1226 1233 PF00069 0.353
MOD_GSK3_1 1258 1265 PF00069 0.365
MOD_GSK3_1 1301 1308 PF00069 0.293
MOD_GSK3_1 1381 1388 PF00069 0.385
MOD_GSK3_1 1414 1421 PF00069 0.353
MOD_GSK3_1 1542 1549 PF00069 0.380
MOD_GSK3_1 1631 1638 PF00069 0.395
MOD_GSK3_1 1643 1650 PF00069 0.404
MOD_GSK3_1 1684 1691 PF00069 0.461
MOD_GSK3_1 1754 1761 PF00069 0.507
MOD_GSK3_1 1772 1779 PF00069 0.334
MOD_GSK3_1 1795 1802 PF00069 0.526
MOD_GSK3_1 191 198 PF00069 0.378
MOD_GSK3_1 212 219 PF00069 0.388
MOD_GSK3_1 294 301 PF00069 0.403
MOD_GSK3_1 33 40 PF00069 0.731
MOD_GSK3_1 346 353 PF00069 0.398
MOD_GSK3_1 409 416 PF00069 0.354
MOD_GSK3_1 432 439 PF00069 0.400
MOD_GSK3_1 449 456 PF00069 0.365
MOD_GSK3_1 515 522 PF00069 0.429
MOD_GSK3_1 546 553 PF00069 0.366
MOD_GSK3_1 58 65 PF00069 0.552
MOD_GSK3_1 7 14 PF00069 0.567
MOD_GSK3_1 75 82 PF00069 0.592
MOD_GSK3_1 847 854 PF00069 0.368
MOD_GSK3_1 900 907 PF00069 0.426
MOD_LATS_1 1215 1221 PF00433 0.257
MOD_LATS_1 131 137 PF00433 0.492
MOD_N-GLC_1 11 16 PF02516 0.567
MOD_N-GLC_1 1165 1170 PF02516 0.406
MOD_N-GLC_1 1196 1201 PF02516 0.367
MOD_N-GLC_1 1223 1228 PF02516 0.432
MOD_N-GLC_1 1283 1288 PF02516 0.435
MOD_N-GLC_1 1356 1361 PF02516 0.386
MOD_N-GLC_1 1684 1689 PF02516 0.467
MOD_N-GLC_1 224 229 PF02516 0.377
MOD_N-GLC_1 37 42 PF02516 0.517
MOD_N-GLC_1 381 386 PF02516 0.367
MOD_N-GLC_1 448 453 PF02516 0.483
MOD_NEK2_1 1015 1020 PF00069 0.458
MOD_NEK2_1 1102 1107 PF00069 0.381
MOD_NEK2_1 1137 1142 PF00069 0.347
MOD_NEK2_1 1165 1170 PF00069 0.381
MOD_NEK2_1 1190 1195 PF00069 0.395
MOD_NEK2_1 1378 1383 PF00069 0.401
MOD_NEK2_1 1385 1390 PF00069 0.388
MOD_NEK2_1 1418 1423 PF00069 0.399
MOD_NEK2_1 1451 1456 PF00069 0.432
MOD_NEK2_1 153 158 PF00069 0.448
MOD_NEK2_1 1536 1541 PF00069 0.362
MOD_NEK2_1 294 299 PF00069 0.481
MOD_NEK2_1 33 38 PF00069 0.525
MOD_NEK2_1 380 385 PF00069 0.373
MOD_NEK2_1 401 406 PF00069 0.517
MOD_NEK2_1 438 443 PF00069 0.455
MOD_NEK2_1 453 458 PF00069 0.343
MOD_NEK2_1 525 530 PF00069 0.385
MOD_NEK2_1 543 548 PF00069 0.270
MOD_NEK2_1 723 728 PF00069 0.518
MOD_NEK2_1 740 745 PF00069 0.290
MOD_NEK2_1 85 90 PF00069 0.700
MOD_NEK2_1 905 910 PF00069 0.449
MOD_NEK2_1 917 922 PF00069 0.491
MOD_NEK2_1 937 942 PF00069 0.429
MOD_NEK2_1 946 951 PF00069 0.457
MOD_NEK2_1 964 969 PF00069 0.510
MOD_NEK2_2 781 786 PF00069 0.397
MOD_NEK2_2 807 812 PF00069 0.433
MOD_PIKK_1 1083 1089 PF00454 0.506
MOD_PIKK_1 1235 1241 PF00454 0.496
MOD_PIKK_1 14 20 PF00454 0.556
MOD_PIKK_1 1463 1469 PF00454 0.635
MOD_PIKK_1 1797 1803 PF00454 0.473
MOD_PIKK_1 471 477 PF00454 0.395
MOD_PK_1 1643 1649 PF00069 0.379
MOD_PK_1 1777 1783 PF00069 0.559
MOD_PK_1 859 865 PF00069 0.370
MOD_PKA_1 1643 1649 PF00069 0.373
MOD_PKA_1 859 865 PF00069 0.375
MOD_PKA_1 888 894 PF00069 0.485
MOD_PKA_2 1083 1089 PF00069 0.353
MOD_PKA_2 131 137 PF00069 0.816
MOD_PKA_2 1629 1635 PF00069 0.405
MOD_PKA_2 1766 1772 PF00069 0.426
MOD_PKA_2 1776 1782 PF00069 0.415
MOD_PKA_2 1809 1815 PF00069 0.483
MOD_PKA_2 298 304 PF00069 0.421
MOD_PKA_2 525 531 PF00069 0.512
MOD_PKA_2 585 591 PF00069 0.384
MOD_PKA_2 723 729 PF00069 0.471
MOD_PKA_2 75 81 PF00069 0.546
MOD_PKA_2 824 830 PF00069 0.229
MOD_PKA_2 85 91 PF00069 0.817
MOD_PKA_2 888 894 PF00069 0.485
MOD_PKB_1 1824 1832 PF00069 0.636
MOD_Plk_1 1156 1162 PF00069 0.344
MOD_Plk_1 1165 1171 PF00069 0.371
MOD_Plk_1 1196 1202 PF00069 0.351
MOD_Plk_1 1223 1229 PF00069 0.323
MOD_Plk_1 1243 1249 PF00069 0.394
MOD_Plk_1 1426 1432 PF00069 0.381
MOD_Plk_1 1684 1690 PF00069 0.461
MOD_Plk_1 1717 1723 PF00069 0.497
MOD_Plk_1 1795 1801 PF00069 0.522
MOD_Plk_1 224 230 PF00069 0.403
MOD_Plk_1 294 300 PF00069 0.418
MOD_Plk_1 381 387 PF00069 0.394
MOD_Plk_1 448 454 PF00069 0.404
MOD_Plk_1 498 504 PF00069 0.423
MOD_Plk_1 747 753 PF00069 0.400
MOD_Plk_1 787 793 PF00069 0.372
MOD_Plk_2-3 1427 1433 PF00069 0.449
MOD_Plk_2-3 1591 1597 PF00069 0.399
MOD_Plk_4 1102 1108 PF00069 0.383
MOD_Plk_4 1111 1117 PF00069 0.374
MOD_Plk_4 1190 1196 PF00069 0.357
MOD_Plk_4 1243 1249 PF00069 0.420
MOD_Plk_4 1263 1269 PF00069 0.245
MOD_Plk_4 1286 1292 PF00069 0.485
MOD_Plk_4 1301 1307 PF00069 0.324
MOD_Plk_4 1330 1336 PF00069 0.354
MOD_Plk_4 153 159 PF00069 0.487
MOD_Plk_4 1647 1653 PF00069 0.454
MOD_Plk_4 1684 1690 PF00069 0.445
MOD_Plk_4 1777 1783 PF00069 0.553
MOD_Plk_4 182 188 PF00069 0.359
MOD_Plk_4 282 288 PF00069 0.417
MOD_Plk_4 318 324 PF00069 0.359
MOD_Plk_4 389 395 PF00069 0.364
MOD_Plk_4 416 422 PF00069 0.427
MOD_Plk_4 425 431 PF00069 0.416
MOD_Plk_4 449 455 PF00069 0.381
MOD_Plk_4 512 518 PF00069 0.403
MOD_Plk_4 525 531 PF00069 0.349
MOD_Plk_4 900 906 PF00069 0.444
MOD_Plk_4 948 954 PF00069 0.539
MOD_Plk_4 964 970 PF00069 0.498
MOD_ProDKin_1 1109 1115 PF00069 0.388
MOD_ProDKin_1 1138 1144 PF00069 0.386
MOD_ProDKin_1 136 142 PF00069 0.554
MOD_ProDKin_1 1737 1743 PF00069 0.409
MOD_ProDKin_1 23 29 PF00069 0.800
MOD_ProDKin_1 233 239 PF00069 0.428
MOD_ProDKin_1 275 281 PF00069 0.463
MOD_ProDKin_1 299 305 PF00069 0.331
MOD_ProDKin_1 313 319 PF00069 0.267
MOD_ProDKin_1 404 410 PF00069 0.269
MOD_ProDKin_1 47 53 PF00069 0.740
MOD_ProDKin_1 531 537 PF00069 0.257
MOD_ProDKin_1 55 61 PF00069 0.787
MOD_ProDKin_1 7 13 PF00069 0.571
MOD_ProDKin_1 94 100 PF00069 0.785
MOD_SUMO_for_1 164 167 PF00179 0.336
MOD_SUMO_rev_2 1274 1279 PF00179 0.431
MOD_SUMO_rev_2 1822 1832 PF00179 0.716
MOD_SUMO_rev_2 629 634 PF00179 0.466
TRG_DiLeu_BaEn_1 318 323 PF01217 0.490
TRG_DiLeu_BaEn_1 748 753 PF01217 0.397
TRG_DiLeu_BaEn_2 1445 1451 PF01217 0.349
TRG_DiLeu_BaEn_2 1531 1537 PF01217 0.368
TRG_DiLeu_BaEn_4 1596 1602 PF01217 0.407
TRG_DiLeu_BaEn_4 1696 1702 PF01217 0.464
TRG_DiLeu_BaLyEn_6 17 22 PF01217 0.543
TRG_DiLeu_BaLyEn_6 459 464 PF01217 0.402
TRG_DiLeu_BaLyEn_6 568 573 PF01217 0.416
TRG_DiLeu_BaLyEn_6 832 837 PF01217 0.452
TRG_ENDOCYTIC_2 1177 1180 PF00928 0.376
TRG_ENDOCYTIC_2 1191 1194 PF00928 0.441
TRG_ENDOCYTIC_2 1248 1251 PF00928 0.477
TRG_ENDOCYTIC_2 127 130 PF00928 0.430
TRG_ENDOCYTIC_2 1324 1327 PF00928 0.257
TRG_ENDOCYTIC_2 1442 1445 PF00928 0.386
TRG_ENDOCYTIC_2 1602 1605 PF00928 0.372
TRG_ENDOCYTIC_2 306 309 PF00928 0.320
TRG_ENDOCYTIC_2 414 417 PF00928 0.389
TRG_ENDOCYTIC_2 440 443 PF00928 0.444
TRG_ENDOCYTIC_2 514 517 PF00928 0.461
TRG_ENDOCYTIC_2 537 540 PF00928 0.395
TRG_ENDOCYTIC_2 57 60 PF00928 0.536
TRG_ENDOCYTIC_2 574 577 PF00928 0.375
TRG_ENDOCYTIC_2 647 650 PF00928 0.352
TRG_ENDOCYTIC_2 818 821 PF00928 0.389
TRG_ER_diArg_1 1064 1066 PF00400 0.540
TRG_ER_diArg_1 142 145 PF00400 0.547
TRG_ER_diArg_1 1462 1465 PF00400 0.538
TRG_ER_diArg_1 1629 1631 PF00400 0.393
TRG_ER_diArg_1 1824 1827 PF00400 0.463
TRG_ER_diArg_1 486 489 PF00400 0.391
TRG_ER_diArg_1 682 684 PF00400 0.605
TRG_ER_diArg_1 718 721 PF00400 0.455
TRG_ER_diArg_1 727 729 PF00400 0.445
TRG_ER_diArg_1 833 835 PF00400 0.462
TRG_NES_CRM1_1 1446 1458 PF08389 0.434
TRG_NES_CRM1_1 151 167 PF08389 0.518
TRG_NES_CRM1_1 831 846 PF08389 0.454
TRG_Pf-PMV_PEXEL_1 1714 1718 PF00026 0.511

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0G2K1Q8 Rattus norvegicus 33% 100%
A0A0N0P411 Leptomonas seymouri 49% 92%
A0A0N1I1A6 Leptomonas seymouri 30% 99%
A0A0N1IH55 Leptomonas seymouri 54% 98%
A0A0S4IQH9 Bodo saltans 33% 97%
A0A0S4IUV3 Bodo saltans 49% 100%
A0A0S4J5Z1 Bodo saltans 50% 100%
A0A0S4J9S9 Bodo saltans 42% 100%
A0A0S4JDK3 Bodo saltans 39% 97%
A0A0S4JTU9 Bodo saltans 36% 100%
A0A1X0NUW1 Trypanosomatidae 45% 100%
A0A1X0NV41 Trypanosomatidae 55% 100%
A0A1X0NZH7 Trypanosomatidae 29% 97%
A0A3Q8I827 Leishmania donovani 55% 97%
A0A3Q8I970 Leishmania donovani 49% 97%
A0A3Q8IBC5 Leishmania donovani 44% 100%
A0A3Q8IHK0 Leishmania donovani 47% 100%
A0A3R7NVN7 Trypanosoma rangeli 47% 100%
A0A3S7WRQ5 Leishmania donovani 55% 100%
A0A3S7X0K7 Leishmania donovani 99% 100%
A0A3S7X0L1 Leishmania donovani 97% 98%
A0A3S7X267 Leishmania donovani 30% 99%
A0A422NUL9 Trypanosoma rangeli 29% 99%
A4H6P2 Leishmania braziliensis 56% 100%
A4H6P6 Leishmania braziliensis 44% 100%
A4H6P7 Leishmania braziliensis 44% 100%
A4H6P8 Leishmania braziliensis 47% 100%
A4H6Q0 Leishmania braziliensis 48% 100%
A4HFM0 Leishmania braziliensis 81% 100%
A4HH69 Leishmania braziliensis 31% 100%
A4HV29 Leishmania infantum 55% 100%
A4HV31 Leishmania infantum 42% 99%
A4HV32 Leishmania infantum 53% 100%
A4HV33 Leishmania infantum 47% 100%
A4HV35 Leishmania infantum 49% 100%
A4I4B4 Leishmania infantum 30% 99%
D0A7B9 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 41% 100%
E9AD74 Leishmania major 94% 100%
E9AD75 Leishmania major 95% 100%
E9ADR4 Leishmania major 29% 100%
E9AM16 Leishmania mexicana (strain MHOM/GT/2001/U1103) 29% 100%
E9ANR1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 54% 100%
E9ANR2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 44% 100%
E9ANR4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 47% 100%
E9ANR6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 49% 100%
E9AYZ8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 92% 100%
E9PU17 Rattus norvegicus 30% 100%
E9PX95 Mus musculus 29% 100%
O94911 Homo sapiens 29% 100%
Q4QGV3 Leishmania major 49% 100%
Q4QGV5 Leishmania major 47% 100%
Q4QGV7 Leishmania major 55% 100%
Q4QGV8 Leishmania major 43% 99%
Q4QGW0 Leishmania major 55% 100%
Q54BT5 Dictyostelium discoideum 28% 100%
Q555Z5 Dictyostelium discoideum 28% 100%
Q84M24 Arabidopsis thaliana 31% 98%
Q8CF82 Rattus norvegicus 29% 100%
Q8K448 Mus musculus 29% 100%
Q8N139 Homo sapiens 26% 100%
Q8R420 Mus musculus 32% 100%
Q8T6J1 Dictyostelium discoideum 29% 100%
Q8T6J2 Dictyostelium discoideum 29% 100%
Q8T6J5 Dictyostelium discoideum 29% 100%
Q8WWZ7 Homo sapiens 30% 100%
Q99758 Homo sapiens 34% 100%
V5B4J7 Trypanosoma cruzi 45% 100%
V5BWI9 Trypanosoma cruzi 44% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS