A small, compact tail-anchored protein related to animal TMEM222 and plant RTE1. Function unknown.. Localization: ER (by homology) / Golgi (by homology)
Uncharacterized Protein, Uncharacterized
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 11 |
| NetGPI | no | yes: 0, no: 11 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0016020 | membrane | 2 | 10 |
| GO:0110165 | cellular anatomical entity | 1 | 10 |
Related structures:
AlphaFold database: A4I2P7
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_PCSK_KEX2_1 | 106 | 108 | PF00082 | 0.295 |
| CLV_PCSK_PC1ET2_1 | 106 | 108 | PF00082 | 0.294 |
| CLV_PCSK_SKI1_1 | 174 | 178 | PF00082 | 0.286 |
| CLV_PCSK_SKI1_1 | 70 | 74 | PF00082 | 0.331 |
| DEG_Nend_UBRbox_2 | 1 | 3 | PF02207 | 0.701 |
| DOC_MAPK_DCC_7 | 177 | 185 | PF00069 | 0.283 |
| DOC_MAPK_gen_1 | 150 | 156 | PF00069 | 0.508 |
| DOC_MAPK_gen_1 | 6 | 15 | PF00069 | 0.666 |
| DOC_MAPK_MEF2A_6 | 177 | 185 | PF00069 | 0.280 |
| DOC_PP1_RVXF_1 | 166 | 173 | PF00149 | 0.505 |
| DOC_PP4_FxxP_1 | 73 | 76 | PF00568 | 0.482 |
| DOC_USP7_MATH_1 | 115 | 119 | PF00917 | 0.550 |
| DOC_WW_Pin1_4 | 30 | 35 | PF00397 | 0.494 |
| DOC_WW_Pin1_4 | 8 | 13 | PF00397 | 0.677 |
| LIG_14-3-3_CanoR_1 | 124 | 132 | PF00244 | 0.443 |
| LIG_14-3-3_CanoR_1 | 168 | 173 | PF00244 | 0.518 |
| LIG_CaM_IQ_9 | 57 | 72 | PF13499 | 0.550 |
| LIG_CSL_BTD_1 | 31 | 34 | PF09270 | 0.494 |
| LIG_LIR_Apic_2 | 39 | 43 | PF02991 | 0.445 |
| LIG_LIR_Gen_1 | 171 | 180 | PF02991 | 0.466 |
| LIG_LIR_LC3C_4 | 182 | 187 | PF02991 | 0.231 |
| LIG_LIR_Nem_3 | 126 | 132 | PF02991 | 0.445 |
| LIG_LIR_Nem_3 | 171 | 175 | PF02991 | 0.606 |
| LIG_PCNA_PIPBox_1 | 125 | 134 | PF02747 | 0.494 |
| LIG_PCNA_yPIPBox_3 | 124 | 132 | PF02747 | 0.494 |
| LIG_PDZ_Class_1 | 191 | 196 | PF00595 | 0.370 |
| LIG_Pex14_1 | 40 | 44 | PF04695 | 0.470 |
| LIG_Pex14_2 | 28 | 32 | PF04695 | 0.452 |
| LIG_SH2_SRC | 86 | 89 | PF00017 | 0.524 |
| LIG_SH2_STAP1 | 112 | 116 | PF00017 | 0.456 |
| LIG_SH2_STAT3 | 58 | 61 | PF00017 | 0.531 |
| LIG_SH2_STAT5 | 169 | 172 | PF00017 | 0.486 |
| LIG_SH2_STAT5 | 86 | 89 | PF00017 | 0.502 |
| LIG_SH3_3 | 10 | 16 | PF00018 | 0.621 |
| LIG_SH3_3 | 28 | 34 | PF00018 | 0.402 |
| LIG_SUMO_SIM_anti_2 | 182 | 188 | PF11976 | 0.442 |
| LIG_SUMO_SIM_par_1 | 188 | 194 | PF11976 | 0.431 |
| LIG_TYR_ITIM | 77 | 82 | PF00017 | 0.445 |
| LIG_WRC_WIRS_1 | 169 | 174 | PF05994 | 0.466 |
| LIG_WRC_WIRS_1 | 87 | 92 | PF05994 | 0.536 |
| MOD_CK1_1 | 118 | 124 | PF00069 | 0.518 |
| MOD_CK2_1 | 140 | 146 | PF00069 | 0.522 |
| MOD_GlcNHglycan | 97 | 100 | PF01048 | 0.301 |
| MOD_LATS_1 | 166 | 172 | PF00433 | 0.466 |
| MOD_N-GLC_2 | 134 | 136 | PF02516 | 0.245 |
| MOD_NEK2_1 | 116 | 121 | PF00069 | 0.479 |
| MOD_PIKK_1 | 50 | 56 | PF00454 | 0.506 |
| MOD_PKA_2 | 123 | 129 | PF00069 | 0.470 |
| MOD_Plk_4 | 135 | 141 | PF00069 | 0.439 |
| MOD_Plk_4 | 179 | 185 | PF00069 | 0.432 |
| MOD_Plk_4 | 36 | 42 | PF00069 | 0.445 |
| MOD_Plk_4 | 86 | 92 | PF00069 | 0.524 |
| MOD_ProDKin_1 | 30 | 36 | PF00069 | 0.501 |
| MOD_ProDKin_1 | 8 | 14 | PF00069 | 0.674 |
| MOD_SUMO_for_1 | 105 | 108 | PF00179 | 0.494 |
| TRG_ENDOCYTIC_2 | 129 | 132 | PF00928 | 0.445 |
| TRG_ENDOCYTIC_2 | 169 | 172 | PF00928 | 0.586 |
| TRG_ENDOCYTIC_2 | 79 | 82 | PF00928 | 0.445 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N1I138 | Leptomonas seymouri | 64% | 99% |
| A0A0S4IX94 | Bodo saltans | 52% | 100% |
| A0A1X0P8A2 | Trypanosomatidae | 55% | 97% |
| A0A3S7X0K2 | Leishmania donovani | 100% | 100% |
| A0A422NWL7 | Trypanosoma rangeli | 54% | 98% |
| A4HFL3 | Leishmania braziliensis | 73% | 100% |
| D0A2W6 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 51% | 100% |
| E9AD67 | Leishmania major | 93% | 100% |
| E9AYZ2 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 91% | 99% |
| F4ITL6 | Arabidopsis thaliana | 34% | 78% |
| Q8BVA2 | Mus musculus | 33% | 94% |
| Q9H0R3 | Homo sapiens | 33% | 94% |
| Q9SD42 | Arabidopsis thaliana | 31% | 85% |
| V5DL06 | Trypanosoma cruzi | 56% | 98% |