CX9C domain-containing protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I2I7_LEIIN

TriTrypDb:

LINF_260030800

Length:

143

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I2I7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I2I7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	109	111	PF00675	0.443
CLV_PCSK_KEX2_1	133	135	PF00082	0.454
CLV_PCSK_KEX2_1	99	101	PF00082	0.385
CLV_PCSK_PC1ET2_1	133	135	PF00082	0.497
CLV_PCSK_PC1ET2_1	99	101	PF00082	0.380
DOC_PP4_FxxP_1	64	67	PF00568	0.556
DOC_USP7_MATH_1	12	16	PF00917	0.551
DOC_USP7_UBL2_3	138	142	PF12436	0.569
LIG_BIR_II_1	1	5	PF00653	0.607
LIG_FHA_2	60	66	PF00498	0.572
LIG_LIR_Apic_2	62	67	PF02991	0.564
LIG_LIR_Gen_1	41	52	PF02991	0.491
LIG_LIR_Gen_1	58	67	PF02991	0.349
LIG_LIR_Nem_3	41	47	PF02991	0.479
LIG_LIR_Nem_3	58	64	PF02991	0.353
LIG_PCNA_yPIPBox_3	76	86	PF02747	0.403
LIG_SH2_CRK	137	141	PF00017	0.432
LIG_SH2_CRK	44	48	PF00017	0.376
LIG_SH2_SRC	25	28	PF00017	0.552
LIG_SH2_STAT5	112	115	PF00017	0.522
LIG_SH2_STAT5	61	64	PF00017	0.578
LIG_SH3_3	26	32	PF00018	0.448
LIG_TYR_ITIM	135	140	PF00017	0.463
MOD_CK2_1	59	65	PF00069	0.568
MOD_GlcNHglycan	1	4	PF01048	0.703
MOD_GlcNHglycan	6	10	PF01048	0.617
MOD_GSK3_1	51	58	PF00069	0.592
MOD_NEK2_1	86	91	PF00069	0.418
MOD_PIKK_1	51	57	PF00454	0.485
MOD_PIKK_1	59	65	PF00454	0.491
TRG_DiLeu_BaEn_4	127	133	PF01217	0.583
TRG_ENDOCYTIC_2	137	140	PF00928	0.427
TRG_ENDOCYTIC_2	44	47	PF00928	0.351
TRG_ENDOCYTIC_2	61	64	PF00928	0.326

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I1F6	Leptomonas seymouri	83%	100%
A0A0S4JH31	Bodo saltans	44%	100%
A0A1X0P7H7	Trypanosomatidae	58%	100%
A0A3Q8ICE5	Leishmania donovani	99%	100%
A0A422P3N4	Trypanosoma rangeli	58%	100%
A4HF95	Leishmania braziliensis	91%	100%
C9ZX16	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	56%	100%
E9AYN1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	100%
Q4Q8U1	Leishmania major	96%	100%