LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
Uncharacterized protein
Gene product:
Protein of unknown function (DUF2946), putative
Species:
Leishmania infantum
UniProt:
A4I2H9_LEIIN
TriTrypDb:
Length:
43

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I2H9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I2H9

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 23 25 PF00675 0.420
CLV_PCSK_KEX2_1 23 25 PF00082 0.420
CLV_PCSK_KEX2_1 41 43 PF00082 0.490
CLV_PCSK_PC1ET2_1 41 43 PF00082 0.490
DEG_Nend_UBRbox_1 1 4 PF02207 0.481
DOC_USP7_MATH_1 11 15 PF00917 0.456
DOC_USP7_UBL2_3 37 41 PF12436 0.486
LIG_SH3_3 5 11 PF00018 0.457
MOD_CK1_1 14 20 PF00069 0.431
MOD_Cter_Amidation 38 41 PF01082 0.487
MOD_GlcNHglycan 16 19 PF01048 0.429
MOD_GSK3_1 10 17 PF00069 0.452
MOD_NEK2_2 16 21 PF00069 0.422
MOD_PKA_2 9 15 PF00069 0.457
TRG_ER_diArg_1 23 26 PF00400 0.424
TRG_ER_diLys_1 40 43 PF00400 0.489

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS