LeishMANIAdb
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Putative peroxisomal membrane protein 4

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
Putative peroxisomal membrane protein 4
Gene product:
peroxisomal membrane protein 4 - putative
Species:
Leishmania infantum
UniProt:
A4I2G8_LEIIN
TriTrypDb:
LINF_260029500 *
Length:
75

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Cellular components
Term Name Level Count
GO:0016020 membrane 2 2
GO:0110165 cellular anatomical entity 1 2

Expansion

Sequence features

A4I2G8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I2G8

Putative motif mimicry

Leishmania From To Domain/Motif Score
DEG_SCF_TRCP1_1 55 61 PF00400 0.491
DOC_CYCLIN_yCln2_LP_2 13 16 PF00134 0.297
DOC_PP2B_LxvP_1 13 16 PF13499 0.297
DOC_USP7_UBL2_3 54 58 PF12436 0.487
DOC_WW_Pin1_4 34 39 PF00397 0.199
DOC_WW_Pin1_4 70 75 PF00397 0.537
LIG_BRCT_BRCA1_1 55 59 PF00533 0.484
LIG_LIR_Gen_1 60 71 PF02991 0.507
LIG_LIR_LC3C_4 64 67 PF02991 0.495
LIG_LIR_Nem_3 60 66 PF02991 0.506
LIG_SH2_CRK 63 67 PF00017 0.500
LIG_SH2_STAP1 63 67 PF00017 0.500
LIG_SH2_STAT5 51 54 PF00017 0.481
LIG_SH2_STAT5 7 10 PF00017 0.321
LIG_SH3_3 68 74 PF00018 0.524
LIG_SUMO_SIM_anti_2 64 69 PF11976 0.500
LIG_UBA3_1 31 40 PF00899 0.199
MOD_CDC14_SPxK_1 37 40 PF00782 0.323
MOD_CDK_SPK_2 70 75 PF00069 0.537
MOD_CDK_SPxK_1 34 40 PF00069 0.199
MOD_GlcNHglycan 55 58 PF01048 0.286
MOD_GSK3_1 41 48 PF00069 0.474
MOD_GSK3_1 53 60 PF00069 0.489
MOD_NEK2_1 41 46 PF00069 0.473
MOD_NEK2_1 53 58 PF00069 0.485
MOD_Plk_4 58 64 PF00069 0.503
MOD_ProDKin_1 34 40 PF00069 0.199
TRG_ENDOCYTIC_2 63 66 PF00928 0.502

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS