Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I2B1_LEIIN

TriTrypDb:

LINF_260023000

Length:

212

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I2B1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I2B1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	137	141	PF00656	0.536
CLV_NRD_NRD_1	150	152	PF00675	0.485
CLV_NRD_NRD_1	51	53	PF00675	0.502
CLV_PCSK_FUR_1	117	121	PF00082	0.520
CLV_PCSK_KEX2_1	119	121	PF00082	0.464
CLV_PCSK_KEX2_1	150	152	PF00082	0.525
CLV_PCSK_PC1ET2_1	119	121	PF00082	0.442
CLV_PCSK_SKI1_1	21	25	PF00082	0.560
CLV_PCSK_SKI1_1	53	57	PF00082	0.510
DOC_WW_Pin1_4	1	6	PF00397	0.700
DOC_WW_Pin1_4	7	12	PF00397	0.622
DOC_WW_Pin1_4	75	80	PF00397	0.613
LIG_Clathr_ClatBox_1	133	137	PF01394	0.421
LIG_Clathr_ClatBox_1	143	147	PF01394	0.446
LIG_FHA_1	165	171	PF00498	0.497
LIG_FHA_1	2	8	PF00498	0.614
LIG_FHA_1	27	33	PF00498	0.453
LIG_FHA_2	64	70	PF00498	0.628
LIG_FHA_2	92	98	PF00498	0.570
LIG_Integrin_RGD_1	164	166	PF01839	0.462
LIG_LIR_Apic_2	34	40	PF02991	0.435
LIG_PCNA_PIPBox_1	126	135	PF02747	0.456
LIG_PCNA_yPIPBox_3	119	133	PF02747	0.463
LIG_PCNA_yPIPBox_3	21	32	PF02747	0.463
LIG_SH2_CRK	37	41	PF00017	0.513
LIG_SH2_NCK_1	37	41	PF00017	0.451
LIG_SH2_SRC	132	135	PF00017	0.472
LIG_SH2_STAP1	198	202	PF00017	0.433
LIG_SH2_STAT5	132	135	PF00017	0.403
LIG_SH3_3	5	11	PF00018	0.617
LIG_SH3_3	62	68	PF00018	0.539
LIG_SUMO_SIM_par_1	132	140	PF11976	0.502
LIG_TRAF2_1	176	179	PF00917	0.507
MOD_CK1_1	15	21	PF00069	0.701
MOD_CK2_1	6	12	PF00069	0.732
MOD_CK2_1	91	97	PF00069	0.613
MOD_GlcNHglycan	161	164	PF01048	0.602
MOD_GSK3_1	132	139	PF00069	0.437
MOD_GSK3_1	26	33	PF00069	0.482
MOD_GSK3_1	63	70	PF00069	0.631
MOD_GSK3_1	73	80	PF00069	0.655
MOD_NEK2_1	153	158	PF00069	0.562
MOD_NMyristoyl	1	7	PF02799	0.617
MOD_PIKK_1	182	188	PF00454	0.466
MOD_PIKK_1	89	95	PF00454	0.639
MOD_PKA_2	73	79	PF00069	0.654
MOD_Plk_4	32	38	PF00069	0.465
MOD_ProDKin_1	1	7	PF00069	0.701
MOD_ProDKin_1	75	81	PF00069	0.605
MOD_SUMO_rev_2	63	73	PF00179	0.612
TRG_DiLeu_BaEn_1	190	195	PF01217	0.488
TRG_ENDOCYTIC_2	121	124	PF00928	0.600
TRG_ER_diArg_1	149	151	PF00400	0.514
TRG_Pf-PMV_PEXEL_1	111	115	PF00026	0.531
TRG_Pf-PMV_PEXEL_1	122	126	PF00026	0.425

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I6B4	Leptomonas seymouri	40%	93%
A0A3S7X005	Leishmania donovani	99%	100%
A4HD51	Leishmania braziliensis	71%	100%
Q4Q914	Leishmania major	90%	100%