LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4I242_LEIIN
TriTrypDb:
LINF_260016300
Length:
1728

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I242
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I242

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 1121 1125 PF00656 0.757
CLV_C14_Caspase3-7 1433 1437 PF00656 0.574
CLV_C14_Caspase3-7 844 848 PF00656 0.769
CLV_C14_Caspase3-7 968 972 PF00656 0.847
CLV_NRD_NRD_1 1071 1073 PF00675 0.797
CLV_NRD_NRD_1 1193 1195 PF00675 0.638
CLV_NRD_NRD_1 1253 1255 PF00675 0.607
CLV_NRD_NRD_1 1589 1591 PF00675 0.818
CLV_NRD_NRD_1 1676 1678 PF00675 0.813
CLV_NRD_NRD_1 1689 1691 PF00675 0.503
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3Q8IDU5 Leishmania donovani 99% 100%
A4HEW8 Leishmania braziliensis 53% 99%
E9AY92 Leishmania mexicana (strain MHOM/GT/2001/U1103) 79% 100%
Q4Q981 Leishmania major 85% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS