RNase III domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I232_LEIIN

TriTrypDb:

LINF_260015300

Length:

367

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I232

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I232

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	175	177	PF00675	0.286
CLV_PCSK_FUR_1	173	177	PF00082	0.270
CLV_PCSK_KEX2_1	175	177	PF00082	0.286
CLV_PCSK_SKI1_1	118	122	PF00082	0.260
CLV_PCSK_SKI1_1	154	158	PF00082	0.282
CLV_PCSK_SKI1_1	176	180	PF00082	0.287
DEG_APCC_DBOX_1	117	125	PF00400	0.275
DOC_CKS1_1	11	16	PF01111	0.387
DOC_CKS1_1	169	174	PF01111	0.252
DOC_CYCLIN_RxL_1	69	77	PF00134	0.264
DOC_PP1_RVXF_1	240	247	PF00149	0.229
DOC_PP2B_LxvP_1	278	281	PF13499	0.307
DOC_PP2B_LxvP_1	84	87	PF13499	0.295
DOC_USP7_MATH_1	287	291	PF00917	0.278
DOC_USP7_UBL2_3	190	194	PF12436	0.275
DOC_USP7_UBL2_3	318	322	PF12436	0.457
DOC_WW_Pin1_4	10	15	PF00397	0.391
DOC_WW_Pin1_4	168	173	PF00397	0.266
DOC_WW_Pin1_4	227	232	PF00397	0.267
DOC_WW_Pin1_4	297	302	PF00397	0.381
DOC_WW_Pin1_4	54	59	PF00397	0.287
DOC_WW_Pin1_4	79	84	PF00397	0.254
LIG_BRCT_BRCA1_1	260	264	PF00533	0.317
LIG_Clathr_ClatBox_1	327	331	PF01394	0.443
LIG_eIF4E_1	249	255	PF01652	0.265
LIG_eIF4E_1	305	311	PF01652	0.461
LIG_FHA_1	18	24	PF00498	0.319
LIG_FHA_2	112	118	PF00498	0.259
LIG_LIR_Apic_2	227	231	PF02991	0.271
LIG_LIR_Apic_2	9	14	PF02991	0.400
LIG_LIR_Gen_1	293	304	PF02991	0.362
LIG_LIR_Gen_1	94	103	PF02991	0.293
LIG_LIR_Nem_3	163	168	PF02991	0.267
LIG_LIR_Nem_3	293	299	PF02991	0.346
LIG_LIR_Nem_3	37	43	PF02991	0.290
LIG_LIR_Nem_3	94	99	PF02991	0.287
LIG_MLH1_MIPbox_1	260	264	PF16413	0.317
LIG_MYND_3	137	141	PF01753	0.298
LIG_Pex14_1	165	169	PF04695	0.269
LIG_Pex14_1	192	196	PF04695	0.255
LIG_Pex14_2	156	160	PF04695	0.259
LIG_Pex14_2	161	165	PF04695	0.255
LIG_PTB_Apo_2	155	162	PF02174	0.258
LIG_SH2_CRK	11	15	PF00017	0.386
LIG_SH2_CRK	169	173	PF00017	0.257
LIG_SH2_CRK	296	300	PF00017	0.381
LIG_SH2_GRB2like	296	299	PF00017	0.377
LIG_SH2_GRB2like	96	99	PF00017	0.273
LIG_SH2_NCK_1	296	300	PF00017	0.381
LIG_SH2_PTP2	228	231	PF00017	0.272
LIG_SH2_SRC	296	299	PF00017	0.377
LIG_SH2_STAP1	196	200	PF00017	0.245
LIG_SH2_STAT5	149	152	PF00017	0.251
LIG_SH2_STAT5	228	231	PF00017	0.272
LIG_SH2_STAT5	263	266	PF00017	0.297
LIG_SH2_STAT5	326	329	PF00017	0.451
LIG_SH3_1	12	18	PF00018	0.380
LIG_SH3_1	329	335	PF00018	0.441
LIG_SH3_3	12	18	PF00018	0.380
LIG_SH3_3	296	302	PF00018	0.376
LIG_SH3_3	329	335	PF00018	0.441
LIG_SH3_3	40	46	PF00018	0.277
LIG_SUMO_SIM_par_1	282	290	PF11976	0.293
LIG_TRAF2_1	281	284	PF00917	0.313
LIG_TRFH_1	305	309	PF08558	0.451
LIG_TYR_ITIM	294	299	PF00017	0.345
LIG_TYR_ITIM	79	84	PF00017	0.254
LIG_UBA3_1	306	315	PF00899	0.473
MOD_CDK_SPK_2	168	173	PF00069	0.266
MOD_CDK_SPxK_1	10	16	PF00069	0.391
MOD_CDK_SPxxK_3	168	175	PF00069	0.266
MOD_CK1_1	290	296	PF00069	0.317
MOD_CK2_1	111	117	PF00069	0.259
MOD_CK2_1	346	352	PF00069	0.509
MOD_CK2_1	79	85	PF00069	0.261
MOD_GlcNHglycan	185	188	PF01048	0.315
MOD_GlcNHglycan	289	292	PF01048	0.306
MOD_GlcNHglycan	355	358	PF01048	0.501
MOD_GSK3_1	314	321	PF00069	0.468
MOD_N-GLC_1	297	302	PF02516	0.381
MOD_N-GLC_1	47	52	PF02516	0.248
MOD_N-GLC_1	63	68	PF02516	0.278
MOD_NEK2_1	144	149	PF00069	0.242
MOD_NEK2_1	258	263	PF00069	0.320
MOD_NEK2_1	47	52	PF00069	0.248
MOD_NEK2_1	74	79	PF00069	0.253
MOD_PIKK_1	47	53	PF00454	0.250
MOD_Plk_1	116	122	PF00069	0.260
MOD_Plk_1	63	69	PF00069	0.279
MOD_Plk_4	144	150	PF00069	0.243
MOD_ProDKin_1	10	16	PF00069	0.391
MOD_ProDKin_1	168	174	PF00069	0.260
MOD_ProDKin_1	227	233	PF00069	0.261
MOD_ProDKin_1	297	303	PF00069	0.383
MOD_ProDKin_1	54	60	PF00069	0.294
MOD_ProDKin_1	79	85	PF00069	0.261
MOD_SUMO_rev_2	102	108	PF00179	0.277
MOD_SUMO_rev_2	119	129	PF00179	0.291
MOD_SUMO_rev_2	308	317	PF00179	0.482
TRG_DiLeu_BaEn_1	85	90	PF01217	0.336
TRG_DiLeu_BaEn_4	283	289	PF01217	0.280
TRG_ENDOCYTIC_2	196	199	PF00928	0.251
TRG_ENDOCYTIC_2	24	27	PF00928	0.291
TRG_ENDOCYTIC_2	296	299	PF00928	0.377
TRG_ENDOCYTIC_2	81	84	PF00928	0.262
TRG_ENDOCYTIC_2	96	99	PF00928	0.273
TRG_ER_diArg_1	174	176	PF00400	0.281
TRG_ER_diArg_1	204	207	PF00400	0.263