Mitochondrial carrier domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I1Y8_LEIIN

TriTrypDb:

LINF_260010600

Length:

702

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

A4I1Y8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I1Y8

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	109	113	PF00656	0.709
CLV_C14_Caspase3-7	12	16	PF00656	0.704
CLV_C14_Caspase3-7	183	187	PF00656	0.441
CLV_C14_Caspase3-7	323	327	PF00656	0.693
CLV_C14_Caspase3-7	420	424	PF00656	0.686
CLV_C14_Caspase3-7	536	540	PF00656	0.639
CLV_MEL_PAP_1	413	419	PF00089	0.489
CLV_NRD_NRD_1	147	149	PF00675	0.405
CLV_NRD_NRD_1	237	239	PF00675	0.642
CLV_NRD_NRD_1	611	613	PF00675	0.362

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4A2	Leptomonas seymouri	49%	99%
A0A3S7WZN2	Leishmania donovani	100%	100%
A4HER1	Leishmania braziliensis	74%	100%
E9AY35	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
Q4Q9D8	Leishmania major	94%	100%

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