PORR domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I1M1_LEIIN

TriTrypDb:

LINF_250024000

Length:

320

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I1M1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I1M1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	136	138	PF00675	0.402
CLV_NRD_NRD_1	305	307	PF00675	0.374
CLV_NRD_NRD_1	317	319	PF00675	0.580
CLV_NRD_NRD_1	60	62	PF00675	0.635
CLV_PCSK_KEX2_1	166	168	PF00082	0.558
CLV_PCSK_KEX2_1	305	307	PF00082	0.374
CLV_PCSK_KEX2_1	60	62	PF00082	0.635
CLV_PCSK_PC1ET2_1	166	168	PF00082	0.558
CLV_PCSK_PC7_1	162	168	PF00082	0.523
CLV_PCSK_SKI1_1	137	141	PF00082	0.497
CLV_PCSK_SKI1_1	265	269	PF00082	0.505
CLV_PCSK_SKI1_1	28	32	PF00082	0.742
CLV_PCSK_SKI1_1	305	309	PF00082	0.512
DEG_APCC_DBOX_1	143	151	PF00400	0.508
DEG_SPOP_SBC_1	83	87	PF00917	0.760
DOC_USP7_MATH_1	216	220	PF00917	0.581
DOC_USP7_MATH_1	257	261	PF00917	0.487
DOC_USP7_MATH_1	40	44	PF00917	0.635
DOC_USP7_MATH_1	70	74	PF00917	0.570
DOC_USP7_MATH_1	83	87	PF00917	0.606
DOC_USP7_MATH_1	90	94	PF00917	0.638
DOC_WW_Pin1_4	130	135	PF00397	0.435
DOC_WW_Pin1_4	221	226	PF00397	0.707
DOC_WW_Pin1_4	51	56	PF00397	0.614
DOC_WW_Pin1_4	84	89	PF00397	0.631
LIG_14-3-3_CanoR_1	167	176	PF00244	0.597
LIG_14-3-3_CanoR_1	28	36	PF00244	0.629
LIG_14-3-3_CanoR_1	297	303	PF00244	0.462
LIG_14-3-3_CanoR_1	305	311	PF00244	0.369
LIG_deltaCOP1_diTrp_1	254	258	PF00928	0.372
LIG_FHA_1	120	126	PF00498	0.495
LIG_FHA_1	171	177	PF00498	0.606
LIG_FHA_1	193	199	PF00498	0.506
LIG_FHA_1	235	241	PF00498	0.612
LIG_FHA_1	46	52	PF00498	0.681
LIG_FHA_2	237	243	PF00498	0.544
LIG_IRF3_LxIS_1	258	264	PF10401	0.483
LIG_LIR_Apic_2	202	207	PF02991	0.561
LIG_LIR_Apic_2	50	55	PF02991	0.671
LIG_LIR_Gen_1	254	263	PF02991	0.389
LIG_LIR_Gen_1	33	44	PF02991	0.664
LIG_LIR_Nem_3	127	132	PF02991	0.408
LIG_LIR_Nem_3	254	258	PF02991	0.372
LIG_LIR_Nem_3	33	39	PF02991	0.661
LIG_LYPXL_yS_3	274	277	PF13949	0.535
LIG_MAD2	138	146	PF02301	0.524
LIG_MYND_1	106	110	PF01753	0.564
LIG_MYND_3	198	202	PF01753	0.542
LIG_Pex14_2	154	158	PF04695	0.405
LIG_REV1ctd_RIR_1	287	297	PF16727	0.496
LIG_SH2_STAT5	250	253	PF00017	0.342
LIG_SH3_1	12	18	PF00018	0.519
LIG_SH3_3	12	18	PF00018	0.690
LIG_SH3_3	173	179	PF00018	0.517
LIG_SH3_3	210	216	PF00018	0.541
LIG_SUMO_SIM_par_1	109	114	PF11976	0.542
LIG_TRAF2_1	146	149	PF00917	0.507
LIG_WRC_WIRS_1	35	40	PF05994	0.552
MOD_CDK_SPxxK_3	130	137	PF00069	0.403
MOD_CDK_SPxxK_3	84	91	PF00069	0.610
MOD_CK1_1	133	139	PF00069	0.419
MOD_CK1_1	77	83	PF00069	0.666
MOD_CK2_1	236	242	PF00069	0.579
MOD_CK2_1	72	78	PF00069	0.765
MOD_DYRK1A_RPxSP_1	130	134	PF00069	0.433
MOD_GlcNHglycan	170	173	PF01048	0.568
MOD_GlcNHglycan	230	233	PF01048	0.581
MOD_GlcNHglycan	42	45	PF01048	0.700
MOD_GSK3_1	166	173	PF00069	0.559
MOD_GSK3_1	257	264	PF00069	0.481
MOD_GSK3_1	30	37	PF00069	0.667
MOD_GSK3_1	40	47	PF00069	0.659
MOD_GSK3_1	70	77	PF00069	0.672
MOD_GSK3_1	78	85	PF00069	0.529
MOD_N-GLC_1	216	221	PF02516	0.452
MOD_N-GLC_1	235	240	PF02516	0.567
MOD_N-GLC_1	261	266	PF02516	0.488
MOD_N-GLC_1	314	319	PF02516	0.474
MOD_NEK2_1	30	35	PF00069	0.728
MOD_NEK2_1	314	319	PF00069	0.538
MOD_PIKK_1	166	172	PF00454	0.551
MOD_PK_1	91	97	PF00069	0.640
MOD_PKA_1	166	172	PF00069	0.551
MOD_PKA_2	166	172	PF00069	0.551
MOD_PKA_2	90	96	PF00069	0.601
MOD_PKB_1	26	34	PF00069	0.505
MOD_Plk_1	216	222	PF00069	0.461
MOD_Plk_1	235	241	PF00069	0.564
MOD_Plk_1	91	97	PF00069	0.640
MOD_Plk_4	114	120	PF00069	0.508
MOD_Plk_4	216	222	PF00069	0.474
MOD_Plk_4	246	252	PF00069	0.394
MOD_Plk_4	298	304	PF00069	0.470
MOD_Plk_4	47	53	PF00069	0.594
MOD_ProDKin_1	130	136	PF00069	0.427
MOD_ProDKin_1	221	227	PF00069	0.712
MOD_ProDKin_1	51	57	PF00069	0.613
MOD_ProDKin_1	84	90	PF00069	0.686
MOD_SUMO_rev_2	260	269	PF00179	0.499
TRG_DiLeu_BaEn_1	114	119	PF01217	0.517
TRG_DiLeu_BaLyEn_6	52	57	PF01217	0.677
TRG_ENDOCYTIC_2	274	277	PF00928	0.529
TRG_ENDOCYTIC_2	286	289	PF00928	0.320
TRG_ER_diArg_1	26	29	PF00400	0.761
TRG_ER_diArg_1	304	306	PF00400	0.373
TRG_NES_CRM1_1	114	127	PF08389	0.461
TRG_Pf-PMV_PEXEL_1	306	311	PF00026	0.432

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IMC8	Leptomonas seymouri	54%	99%
A0A3S7WZA0	Leishmania donovani	100%	100%
A0A422NGK2	Trypanosoma rangeli	32%	100%
A4HEG9	Leishmania braziliensis	67%	100%
C9ZK64	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	98%
E9AXQ5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	98%
Q4Q9R6	Leishmania major	91%	100%
V5BHV8	Trypanosoma cruzi	33%	100%