ATPase beta subunit, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ATP synthase subunit beta - mitochondrial - putative

Species:

Leishmania infantum

UniProt:

A4I1G0_LEIIN

TriTrypDb:

LINF_250017900

Length:

268

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 10

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I1G0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I1G0

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	3
GO:0006163	purine nucleotide metabolic process	5	3
GO:0006725	cellular aromatic compound metabolic process	3	3
GO:0006753	nucleoside phosphate metabolic process	4	3
GO:0006793	phosphorus metabolic process	3	3
GO:0006796	phosphate-containing compound metabolic process	4	3
GO:0006807	nitrogen compound metabolic process	2	3
GO:0006810	transport	3	3
GO:0006811	monoatomic ion transport	4	3
GO:0006812	monoatomic cation transport	5	3
GO:0008152	metabolic process	1	3
GO:0009117	nucleotide metabolic process	5	3
GO:0009141	nucleoside triphosphate metabolic process	5	3
GO:0009144	purine nucleoside triphosphate metabolic process	6	3
GO:0009150	purine ribonucleotide metabolic process	6	3
GO:0009199	ribonucleoside triphosphate metabolic process	6	3
GO:0009205	purine ribonucleoside triphosphate metabolic process	7	3
GO:0009259	ribonucleotide metabolic process	5	3
GO:0009987	cellular process	1	3
GO:0019637	organophosphate metabolic process	3	3
GO:0019693	ribose phosphate metabolic process	4	3
GO:0034220	monoatomic ion transmembrane transport	3	3
GO:0034641	cellular nitrogen compound metabolic process	3	3
GO:0044237	cellular metabolic process	2	3
GO:0044238	primary metabolic process	2	3
GO:0044281	small molecule metabolic process	2	3
GO:0046034	ATP metabolic process	7	3
GO:0046483	heterocycle metabolic process	3	3
GO:0051179	localization	1	3
GO:0051234	establishment of localization	2	3
GO:0055085	transmembrane transport	2	3
GO:0055086	nucleobase-containing small molecule metabolic process	3	3
GO:0071704	organic substance metabolic process	2	3
GO:0072521	purine-containing compound metabolic process	4	3
GO:0098655	monoatomic cation transmembrane transport	4	3
GO:0098660	inorganic ion transmembrane transport	4	3
GO:0098662	inorganic cation transmembrane transport	5	3
GO:1901135	carbohydrate derivative metabolic process	3	3
GO:1901360	organic cyclic compound metabolic process	3	3
GO:1901564	organonitrogen compound metabolic process	3	3
GO:1902600	proton transmembrane transport	6	3

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	3
GO:0005488	binding	1	3
GO:0005524	ATP binding	5	3
GO:0017076	purine nucleotide binding	4	3
GO:0030554	adenyl nucleotide binding	5	3
GO:0032553	ribonucleotide binding	3	3
GO:0032555	purine ribonucleotide binding	4	3
GO:0032559	adenyl ribonucleotide binding	5	3
GO:0035639	purine ribonucleoside triphosphate binding	4	3
GO:0036094	small molecule binding	2	3
GO:0043167	ion binding	2	3
GO:0043168	anion binding	3	3
GO:0097159	organic cyclic compound binding	2	3
GO:0097367	carbohydrate derivative binding	2	3
GO:1901265	nucleoside phosphate binding	3	3
GO:1901363	heterocyclic compound binding	2	3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	11	13	PF00675	0.787
CLV_PCSK_KEX2_1	11	13	PF00082	0.787
CLV_PCSK_SKI1_1	243	247	PF00082	0.249
DEG_APCC_DBOX_1	117	125	PF00400	0.576
DEG_Nend_Nbox_1	1	3	PF02207	0.769
DOC_MAPK_gen_1	219	228	PF00069	0.249
DOC_MAPK_MEF2A_6	221	230	PF00069	0.249
DOC_MAPK_MEF2A_6	71	79	PF00069	0.512
DOC_PP2B_LxvP_1	172	175	PF13499	0.424
DOC_USP7_MATH_1	18	22	PF00917	0.666
DOC_USP7_UBL2_3	100	104	PF12436	0.512
DOC_USP7_UBL2_3	239	243	PF12436	0.249
LIG_14-3-3_CterR_2	264	268	PF00244	0.409
LIG_APCC_ABBA_1	144	149	PF00400	0.630
LIG_APCC_ABBAyCdc20_2	143	149	PF00400	0.631
LIG_FHA_1	162	168	PF00498	0.511
LIG_FHA_1	191	197	PF00498	0.331
LIG_FHA_1	64	70	PF00498	0.512
LIG_FHA_1	74	80	PF00498	0.346
LIG_FHA_1	93	99	PF00498	0.188
LIG_FHA_2	59	65	PF00498	0.512
LIG_KLC1_Yacidic_2	225	229	PF13176	0.249
LIG_LIR_Gen_1	224	235	PF02991	0.296
LIG_LIR_Nem_3	211	216	PF02991	0.259
LIG_SH2_STAT3	39	42	PF00017	0.512
LIG_SH2_STAT5	176	179	PF00017	0.321
LIG_SH2_STAT5	227	230	PF00017	0.412
LIG_SH2_STAT5	39	42	PF00017	0.512
LIG_SUMO_SIM_anti_2	193	198	PF11976	0.424
LIG_SUMO_SIM_anti_2	76	81	PF11976	0.512
LIG_SUMO_SIM_par_1	192	198	PF11976	0.424
LIG_SUMO_SIM_par_1	72	78	PF11976	0.512
LIG_UBA3_1	196	205	PF00899	0.424
LIG_UBA3_1	98	104	PF00899	0.337
MOD_GlcNHglycan	20	23	PF01048	0.777
MOD_GlcNHglycan	6	9	PF01048	0.766
MOD_GSK3_1	100	107	PF00069	0.351
MOD_GSK3_1	158	165	PF00069	0.548
MOD_GSK3_1	217	224	PF00069	0.453
MOD_N-GLC_1	110	115	PF02516	0.588
MOD_NEK2_1	230	235	PF00069	0.271
MOD_NEK2_2	208	213	PF00069	0.424
MOD_PIKK_1	38	44	PF00454	0.512
MOD_PKA_2	117	123	PF00069	0.582
MOD_PKB_1	219	227	PF00069	0.249
MOD_PKB_1	258	266	PF00069	0.390
MOD_Plk_1	110	116	PF00069	0.585
MOD_Plk_1	158	164	PF00069	0.561
MOD_Plk_2-3	73	79	PF00069	0.512
MOD_Plk_4	158	164	PF00069	0.561
MOD_Plk_4	190	196	PF00069	0.424
MOD_SUMO_for_1	238	241	PF00179	0.249
MOD_SUMO_rev_2	237	245	PF00179	0.249
TRG_ENDOCYTIC_2	227	230	PF00928	0.249
TRG_ENDOCYTIC_2	248	251	PF00928	0.249
TRG_ER_diArg_1	10	12	PF00400	0.779
TRG_ER_diArg_1	258	261	PF00400	0.238
TRG_ER_diArg_1	264	267	PF00400	0.396

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HEJ4	Leishmania braziliensis	94%	100%
Q24751	Drosophila virilis	63%	100%