Mediator of RNA polymerase II transcription subunit 21

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I1A5_LEIIN

TriTrypDb:

LINF_250011700

Length:

162


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Could not find GO cellular_component term for this entry.

A4I1A5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I1A5


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	134	136	PF00675	0.595
CLV_NRD_NRD_1	76	78	PF00675	0.603
CLV_NRD_NRD_1	83	85	PF00675	0.561
CLV_PCSK_KEX2_1	134	136	PF00082	0.562
CLV_PCSK_KEX2_1	75	77	PF00082	0.614
CLV_PCSK_KEX2_1	83	85	PF00082	0.553
CLV_PCSK_SKI1_1	90	94	PF00082	0.579
CLV_Separin_Metazoa	80	84	PF03568	0.523
DOC_USP7_MATH_1	126	130	PF00917	0.553
LIG_Actin_WH2_2	79	96	PF00022	0.508
LIG_APCC_ABBA_1	137	142	PF00400	0.552
LIG_BIR_II_1	1	5	PF00653	0.505
LIG_BIR_III_2	29	33	PF00653	0.531
LIG_BIR_III_4	105	109	PF00653	0.580
LIG_eIF4E_1	140	146	PF01652	0.503
LIG_FHA_2	146	152	PF00498	0.495
LIG_FHA_2	69	75	PF00498	0.578
LIG_Rb_pABgroove_1	134	142	PF01858	0.555
LIG_SH2_NCK_1	140	144	PF00017	0.435
LIG_SH2_SRC	140	143	PF00017	0.437
LIG_SH2_STAP1	140	144	PF00017	0.518
LIG_SH2_STAT5	15	18	PF00017	0.519
LIG_SH3_3	43	49	PF00018	0.563
LIG_SUMO_SIM_par_1	112	119	PF11976	0.582
LIG_SUMO_SIM_par_1	135	142	PF11976	0.554
MOD_CK2_1	145	151	PF00069	0.493
MOD_CK2_1	68	74	PF00069	0.536
MOD_Cter_Amidation	132	135	PF01082	0.563
MOD_GlcNHglycan	105	109	PF01048	0.613
MOD_GlcNHglycan	128	131	PF01048	0.570
MOD_NEK2_1	145	150	PF00069	0.531
MOD_NEK2_1	155	160	PF00069	0.595
MOD_PKA_2	68	74	PF00069	0.582
MOD_Plk_4	31	37	PF00069	0.686
MOD_Plk_4	59	65	PF00069	0.634
TRG_ER_diArg_1	134	136	PF00400	0.595
TRG_ER_diArg_1	75	77	PF00400	0.503
TRG_ER_diArg_1	82	84	PF00400	0.486
TRG_Pf-PMV_PEXEL_1	76	80	PF00026	0.615
TRG_Pf-PMV_PEXEL_1	84	89	PF00026	0.454


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P682	Leptomonas seymouri	64%	100%
A0A1X0P4E5	Trypanosomatidae	33%	100%
A0A3Q8IN81	Leishmania donovani	100%	100%
A0A3R7L9Z8	Trypanosoma rangeli	33%	93%
A4HEF4	Leishmania braziliensis	83%	100%
D0A5J7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	100%
E9AXE1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
Q4QA31	Leishmania major	93%	100%
V5B7Q6	Trypanosoma cruzi	33%	100%