LeishMANIAdb
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DNA-directed RNA polymerase subunit beta

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
DNA-directed RNA polymerase subunit beta
Gene product:
RNA polymerase I second largest subunit - putative
Species:
Leishmania infantum
UniProt:
A4I1A3_LEIIN
TriTrypDb:
LINF_250011500
Length:
1616

Annotations

Annotations by Jardim et al.

Polymerase, DNA-directed RNA polymerase

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0000428 DNA-directed RNA polymerase complex 4 12
GO:0005634 nucleus 5 11
GO:0030880 RNA polymerase complex 3 12
GO:0032991 protein-containing complex 1 12
GO:0043226 organelle 2 12
GO:0043227 membrane-bounded organelle 3 11
GO:0043229 intracellular organelle 3 12
GO:0043231 intracellular membrane-bounded organelle 4 11
GO:0061695 transferase complex, transferring phosphorus-containing groups 4 12
GO:0110165 cellular anatomical entity 1 12
GO:0140535 intracellular protein-containing complex 2 12
GO:1902494 catalytic complex 2 12
GO:1990234 transferase complex 3 12
GO:0005654 nucleoplasm 2 1
GO:0005730 nucleolus 5 1
GO:0005736 RNA polymerase I complex 4 1
GO:0043228 non-membrane-bounded organelle 3 1
GO:0043232 intracellular non-membrane-bounded organelle 4 1
GO:0055029 nuclear DNA-directed RNA polymerase complex 3 1
GO:0140513 nuclear protein-containing complex 2 1

Expansion

Sequence features

A4I1A3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I1A3

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 12
GO:0006351 DNA-templated transcription 7 12
GO:0006725 cellular aromatic compound metabolic process 3 12
GO:0006807 nitrogen compound metabolic process 2 12
GO:0008152 metabolic process 1 12
GO:0009058 biosynthetic process 2 12
GO:0009059 macromolecule biosynthetic process 4 12
GO:0009987 cellular process 1 12
GO:0016070 RNA metabolic process 5 12
GO:0018130 heterocycle biosynthetic process 4 12
GO:0019438 aromatic compound biosynthetic process 4 12
GO:0032774 RNA biosynthetic process 5 12
GO:0034641 cellular nitrogen compound metabolic process 3 12
GO:0034654 nucleobase-containing compound biosynthetic process 4 12
GO:0043170 macromolecule metabolic process 3 12
GO:0044237 cellular metabolic process 2 12
GO:0044238 primary metabolic process 2 12
GO:0044249 cellular biosynthetic process 3 12
GO:0044271 cellular nitrogen compound biosynthetic process 4 12
GO:0046483 heterocycle metabolic process 3 12
GO:0071704 organic substance metabolic process 2 12
GO:0090304 nucleic acid metabolic process 4 12
GO:0097659 nucleic acid-templated transcription 6 12
GO:1901360 organic cyclic compound metabolic process 3 12
GO:1901362 organic cyclic compound biosynthetic process 4 12
GO:1901576 organic substance biosynthetic process 3 12
Molecular functions
Term Name Level Count
GO:0001882 nucleoside binding 3 12
GO:0003676 nucleic acid binding 3 12
GO:0003677 DNA binding 4 12
GO:0003824 catalytic activity 1 12
GO:0003899 DNA-directed 5'-3' RNA polymerase activity 6 12
GO:0005488 binding 1 12
GO:0016740 transferase activity 2 12
GO:0016772 transferase activity, transferring phosphorus-containing groups 3 12
GO:0016779 nucleotidyltransferase activity 4 12
GO:0032549 ribonucleoside binding 4 12
GO:0034062 5'-3' RNA polymerase activity 5 12
GO:0036094 small molecule binding 2 12
GO:0097159 organic cyclic compound binding 2 12
GO:0097367 carbohydrate derivative binding 2 12
GO:0097747 RNA polymerase activity 4 12
GO:0140098 catalytic activity, acting on RNA 3 12
GO:0140640 catalytic activity, acting on a nucleic acid 2 12
GO:1901363 heterocyclic compound binding 2 12

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1577 1581 PF00656 0.534
CLV_NRD_NRD_1 1006 1008 PF00675 0.255
CLV_NRD_NRD_1 1051 1053 PF00675 0.555
CLV_NRD_NRD_1 1090 1092 PF00675 0.490
CLV_NRD_NRD_1 1142 1144 PF00675 0.248
CLV_NRD_NRD_1 1503 1505 PF00675 0.248
CLV_NRD_NRD_1 306 308 PF00675 0.491
CLV_NRD_NRD_1 34 36 PF00675 0.668
CLV_NRD_NRD_1 387 389 PF00675 0.449
CLV_NRD_NRD_1 576 578 PF00675 0.248
CLV_NRD_NRD_1 627 629 PF00675 0.297
CLV_NRD_NRD_1 682 684 PF00675 0.248
CLV_NRD_NRD_1 721 723 PF00675 0.308
CLV_NRD_NRD_1 791 793 PF00675 0.444
CLV_NRD_NRD_1 889 891 PF00675 0.249
CLV_NRD_NRD_1 95 97 PF00675 0.478
CLV_NRD_NRD_1 989 991 PF00675 0.249
CLV_PCSK_FUR_1 32 36 PF00082 0.641
CLV_PCSK_FUR_1 550 554 PF00082 0.248
CLV_PCSK_KEX2_1 1006 1008 PF00082 0.254
CLV_PCSK_KEX2_1 1253 1255 PF00082 0.248
CLV_PCSK_KEX2_1 1284 1286 PF00082 0.259
CLV_PCSK_KEX2_1 1505 1507 PF00082 0.248
CLV_PCSK_KEX2_1 306 308 PF00082 0.482
CLV_PCSK_KEX2_1 34 36 PF00082 0.644
CLV_PCSK_KEX2_1 387 389 PF00082 0.449
CLV_PCSK_KEX2_1 552 554 PF00082 0.248
CLV_PCSK_KEX2_1 627 629 PF00082 0.297
CLV_PCSK_KEX2_1 682 684 PF00082 0.248
CLV_PCSK_KEX2_1 791 793 PF00082 0.484
CLV_PCSK_PC1ET2_1 1253 1255 PF00082 0.259
CLV_PCSK_PC1ET2_1 1284 1286 PF00082 0.259
CLV_PCSK_PC1ET2_1 1505 1507 PF00082 0.248
CLV_PCSK_PC1ET2_1 552 554 PF00082 0.248
CLV_PCSK_SKI1_1 1053 1057 PF00082 0.592
CLV_PCSK_SKI1_1 1121 1125 PF00082 0.246
CLV_PCSK_SKI1_1 1144 1148 PF00082 0.241
CLV_PCSK_SKI1_1 1203 1207 PF00082 0.275
CLV_PCSK_SKI1_1 1214 1218 PF00082 0.211
CLV_PCSK_SKI1_1 1492 1496 PF00082 0.248
CLV_PCSK_SKI1_1 1557 1561 PF00082 0.259
CLV_PCSK_SKI1_1 1604 1608 PF00082 0.259
CLV_PCSK_SKI1_1 259 263 PF00082 0.497
CLV_PCSK_SKI1_1 307 311 PF00082 0.491
CLV_PCSK_SKI1_1 481 485 PF00082 0.272
CLV_PCSK_SKI1_1 517 521 PF00082 0.257
CLV_PCSK_SKI1_1 534 538 PF00082 0.207
CLV_PCSK_SKI1_1 604 608 PF00082 0.253
CLV_PCSK_SKI1_1 683 687 PF00082 0.248
CLV_PCSK_SKI1_1 791 795 PF00082 0.473
CLV_PCSK_SKI1_1 797 801 PF00082 0.551
CLV_PCSK_SKI1_1 990 994 PF00082 0.239
CLV_Separin_Metazoa 136 140 PF03568 0.574
DEG_APCC_DBOX_1 480 488 PF00400 0.459
DEG_APCC_DBOX_1 682 690 PF00400 0.448
DEG_APCC_DBOX_1 796 804 PF00400 0.466
DEG_APCC_DBOX_1 95 103 PF00400 0.444
DEG_SCF_FBW7_2 88 93 PF00400 0.336
DOC_CKS1_1 109 114 PF01111 0.617
DOC_CKS1_1 380 385 PF01111 0.421
DOC_CYCLIN_RxL_1 729 739 PF00134 0.534
DOC_CYCLIN_RxL_1 789 798 PF00134 0.524
DOC_CYCLIN_RxL_1 986 997 PF00134 0.400
DOC_CYCLIN_yCln2_LP_2 1058 1064 PF00134 0.360
DOC_CYCLIN_yCln2_LP_2 583 589 PF00134 0.534
DOC_CYCLIN_yCln2_LP_2 799 802 PF00134 0.483
DOC_MAPK_gen_1 1024 1033 PF00069 0.540
DOC_MAPK_gen_1 1052 1060 PF00069 0.572
DOC_MAPK_gen_1 1502 1512 PF00069 0.448
DOC_MAPK_gen_1 253 262 PF00069 0.407
DOC_MAPK_gen_1 577 585 PF00069 0.425
DOC_MAPK_gen_1 722 730 PF00069 0.508
DOC_MAPK_gen_1 94 104 PF00069 0.541
DOC_MAPK_gen_1 986 995 PF00069 0.400
DOC_MAPK_MEF2A_6 1358 1365 PF00069 0.459
DOC_MAPK_MEF2A_6 1392 1401 PF00069 0.514
DOC_MAPK_MEF2A_6 523 530 PF00069 0.448
DOC_MAPK_MEF2A_6 578 587 PF00069 0.426
DOC_MAPK_NFAT4_5 1358 1366 PF00069 0.459
DOC_PP1_RVXF_1 398 404 PF00149 0.388
DOC_PP1_RVXF_1 575 582 PF00149 0.448
DOC_PP1_RVXF_1 99 105 PF00149 0.558
DOC_PP2B_LxvP_1 583 586 PF13499 0.534
DOC_PP2B_LxvP_1 799 802 PF13499 0.483
DOC_PP4_FxxP_1 1339 1342 PF00568 0.454
DOC_PP4_FxxP_1 1543 1546 PF00568 0.534
DOC_PP4_FxxP_1 380 383 PF00568 0.379
DOC_PP4_FxxP_1 848 851 PF00568 0.382
DOC_USP7_MATH_1 1077 1081 PF00917 0.464
DOC_USP7_MATH_1 124 128 PF00917 0.562
DOC_USP7_MATH_1 1255 1259 PF00917 0.497
DOC_USP7_MATH_1 1373 1377 PF00917 0.480
DOC_USP7_MATH_1 1388 1392 PF00917 0.414
DOC_USP7_MATH_1 142 146 PF00917 0.579
DOC_USP7_MATH_1 1575 1579 PF00917 0.534
DOC_USP7_MATH_1 17 21 PF00917 0.734
DOC_USP7_MATH_1 203 207 PF00917 0.394
DOC_USP7_MATH_1 254 258 PF00917 0.493
DOC_USP7_MATH_1 342 346 PF00917 0.527
DOC_USP7_MATH_1 418 422 PF00917 0.638
DOC_USP7_MATH_1 425 429 PF00917 0.592
DOC_USP7_MATH_1 665 669 PF00917 0.525
DOC_USP7_MATH_1 851 855 PF00917 0.396
DOC_USP7_MATH_1 950 954 PF00917 0.505
DOC_USP7_MATH_2 178 184 PF00917 0.485
DOC_USP7_UBL2_3 121 125 PF12436 0.512
DOC_USP7_UBL2_3 1221 1225 PF12436 0.501
DOC_USP7_UBL2_3 97 101 PF12436 0.486
DOC_WW_Pin1_4 1008 1013 PF00397 0.534
DOC_WW_Pin1_4 108 113 PF00397 0.582
DOC_WW_Pin1_4 1116 1121 PF00397 0.448
DOC_WW_Pin1_4 1376 1381 PF00397 0.441
DOC_WW_Pin1_4 233 238 PF00397 0.538
DOC_WW_Pin1_4 379 384 PF00397 0.385
DOC_WW_Pin1_4 693 698 PF00397 0.453
DOC_WW_Pin1_4 710 715 PF00397 0.385
DOC_WW_Pin1_4 86 91 PF00397 0.353
DOC_WW_Pin1_4 902 907 PF00397 0.438
DOC_WW_Pin1_4 923 928 PF00397 0.485
DOC_WW_Pin1_4 973 978 PF00397 0.485
LIG_14-3-3_CanoR_1 1203 1212 PF00244 0.520
LIG_14-3-3_CanoR_1 1254 1260 PF00244 0.534
LIG_14-3-3_CanoR_1 128 138 PF00244 0.511
LIG_14-3-3_CanoR_1 1392 1396 PF00244 0.438
LIG_14-3-3_CanoR_1 1483 1491 PF00244 0.508
LIG_14-3-3_CanoR_1 1557 1565 PF00244 0.459
LIG_14-3-3_CanoR_1 253 262 PF00244 0.452
LIG_14-3-3_CanoR_1 315 323 PF00244 0.437
LIG_14-3-3_CanoR_1 433 443 PF00244 0.503
LIG_14-3-3_CanoR_1 885 893 PF00244 0.448
LIG_14-3-3_CanoR_1 947 956 PF00244 0.474
LIG_14-3-3_CanoR_1 990 996 PF00244 0.483
LIG_Actin_WH2_2 1594 1610 PF00022 0.472
LIG_Actin_WH2_2 344 360 PF00022 0.427
LIG_Actin_WH2_2 470 487 PF00022 0.448
LIG_Actin_WH2_2 53 70 PF00022 0.536
LIG_AP2alpha_2 1290 1292 PF02296 0.534
LIG_APCC_ABBA_1 1031 1036 PF00400 0.459
LIG_APCC_ABBA_1 528 533 PF00400 0.459
LIG_APCC_ABBA_1 734 739 PF00400 0.534
LIG_APCC_ABBA_1 88 93 PF00400 0.395
LIG_BIR_II_1 1 5 PF00653 0.589
LIG_BIR_III_2 1009 1013 PF00653 0.534
LIG_BRCT_BRCA1_1 654 658 PF00533 0.448
LIG_deltaCOP1_diTrp_1 464 473 PF00928 0.335
LIG_deltaCOP1_diTrp_1 673 679 PF00928 0.448
LIG_DLG_GKlike_1 1547 1554 PF00625 0.553
LIG_eIF4E_1 1035 1041 PF01652 0.469
LIG_eIF4E_1 1444 1450 PF01652 0.459
LIG_FHA_1 1000 1006 PF00498 0.496
LIG_FHA_1 1013 1019 PF00498 0.488
LIG_FHA_1 1099 1105 PF00498 0.502
LIG_FHA_1 1205 1211 PF00498 0.508
LIG_FHA_1 1240 1246 PF00498 0.448
LIG_FHA_1 1331 1337 PF00498 0.448
LIG_FHA_1 1358 1364 PF00498 0.458
LIG_FHA_1 1377 1383 PF00498 0.369
LIG_FHA_1 1401 1407 PF00498 0.534
LIG_FHA_1 1577 1583 PF00498 0.459
LIG_FHA_1 1607 1613 PF00498 0.633
LIG_FHA_1 222 228 PF00498 0.463
LIG_FHA_1 352 358 PF00498 0.514
LIG_FHA_1 36 42 PF00498 0.676
LIG_FHA_1 592 598 PF00498 0.510
LIG_FHA_1 694 700 PF00498 0.438
LIG_FHA_1 729 735 PF00498 0.525
LIG_FHA_1 75 81 PF00498 0.497
LIG_FHA_1 835 841 PF00498 0.426
LIG_FHA_1 930 936 PF00498 0.538
LIG_FHA_1 960 966 PF00498 0.368
LIG_FHA_2 1184 1190 PF00498 0.448
LIG_FHA_2 131 137 PF00498 0.538
LIG_FHA_2 1344 1350 PF00498 0.508
LIG_FHA_2 1419 1425 PF00498 0.520
LIG_FHA_2 409 415 PF00498 0.549
LIG_FHA_2 50 56 PF00498 0.495
LIG_FHA_2 565 571 PF00498 0.448
LIG_FHA_2 878 884 PF00498 0.472
LIG_FHA_2 952 958 PF00498 0.499
LIG_GBD_Chelix_1 1428 1436 PF00786 0.334
LIG_HCF-1_HBM_1 1267 1270 PF13415 0.448
LIG_LIR_Apic_2 1017 1023 PF02991 0.459
LIG_LIR_Apic_2 1540 1546 PF02991 0.534
LIG_LIR_Apic_2 391 396 PF02991 0.388
LIG_LIR_Apic_2 455 461 PF02991 0.489
LIG_LIR_Apic_2 845 851 PF02991 0.402
LIG_LIR_Gen_1 1069 1079 PF02991 0.377
LIG_LIR_Gen_1 1417 1426 PF02991 0.448
LIG_LIR_Gen_1 199 209 PF02991 0.353
LIG_LIR_Gen_1 308 316 PF02991 0.452
LIG_LIR_Gen_1 437 448 PF02991 0.423
LIG_LIR_Gen_1 454 461 PF02991 0.192
LIG_LIR_Gen_1 464 474 PF02991 0.292
LIG_LIR_Gen_1 639 648 PF02991 0.444
LIG_LIR_Gen_1 655 665 PF02991 0.437
LIG_LIR_Gen_1 721 730 PF02991 0.499
LIG_LIR_Gen_1 853 863 PF02991 0.358
LIG_LIR_Gen_1 89 99 PF02991 0.474
LIG_LIR_Nem_3 1069 1075 PF02991 0.431
LIG_LIR_Nem_3 1165 1169 PF02991 0.448
LIG_LIR_Nem_3 1267 1273 PF02991 0.462
LIG_LIR_Nem_3 1306 1311 PF02991 0.448
LIG_LIR_Nem_3 1417 1422 PF02991 0.448
LIG_LIR_Nem_3 1461 1466 PF02991 0.451
LIG_LIR_Nem_3 1490 1494 PF02991 0.508
LIG_LIR_Nem_3 199 204 PF02991 0.340
LIG_LIR_Nem_3 436 442 PF02991 0.398
LIG_LIR_Nem_3 452 456 PF02991 0.312
LIG_LIR_Nem_3 464 470 PF02991 0.326
LIG_LIR_Nem_3 492 497 PF02991 0.448
LIG_LIR_Nem_3 639 643 PF02991 0.442
LIG_LIR_Nem_3 655 661 PF02991 0.502
LIG_LIR_Nem_3 673 679 PF02991 0.448
LIG_LIR_Nem_3 89 95 PF02991 0.443
LIG_LIR_Nem_3 895 900 PF02991 0.448
LIG_LYPXL_yS_3 1270 1273 PF13949 0.448
LIG_MAD2 578 586 PF02301 0.488
LIG_MYND_1 697 701 PF01753 0.488
LIG_NRBOX 169 175 PF00104 0.523
LIG_NRBOX 515 521 PF00104 0.459
LIG_NRBOX 601 607 PF00104 0.534
LIG_NRBOX 830 836 PF00104 0.451
LIG_PCNA_PIPBox_1 500 509 PF02747 0.448
LIG_PCNA_yPIPBox_3 1425 1438 PF02747 0.534
LIG_PCNA_yPIPBox_3 495 507 PF02747 0.448
LIG_PDZ_Class_3 1611 1616 PF00595 0.629
LIG_Pex14_1 675 679 PF04695 0.448
LIG_Pex14_2 1060 1064 PF04695 0.420
LIG_Pex14_2 466 470 PF04695 0.447
LIG_Pex14_2 777 781 PF04695 0.400
LIG_Pex14_2 865 869 PF04695 0.448
LIG_REV1ctd_RIR_1 89 98 PF16727 0.438
LIG_SH2_CRK 1469 1473 PF00017 0.448
LIG_SH2_CRK 1491 1495 PF00017 0.534
LIG_SH2_CRK 223 227 PF00017 0.488
LIG_SH2_CRK 393 397 PF00017 0.381
LIG_SH2_CRK 456 460 PF00017 0.419
LIG_SH2_CRK 897 901 PF00017 0.472
LIG_SH2_PTP2 1020 1023 PF00017 0.472
LIG_SH2_PTP2 640 643 PF00017 0.503
LIG_SH2_STAP1 1555 1559 PF00017 0.448
LIG_SH2_STAP1 456 460 PF00017 0.405
LIG_SH2_STAT3 1095 1098 PF00017 0.440
LIG_SH2_STAT3 1152 1155 PF00017 0.448
LIG_SH2_STAT3 565 568 PF00017 0.553
LIG_SH2_STAT3 849 852 PF00017 0.385
LIG_SH2_STAT5 1020 1023 PF00017 0.456
LIG_SH2_STAT5 1032 1035 PF00017 0.408
LIG_SH2_STAT5 1152 1155 PF00017 0.463
LIG_SH2_STAT5 1157 1160 PF00017 0.413
LIG_SH2_STAT5 1185 1188 PF00017 0.471
LIG_SH2_STAT5 1280 1283 PF00017 0.463
LIG_SH2_STAT5 1300 1303 PF00017 0.317
LIG_SH2_STAT5 223 226 PF00017 0.534
LIG_SH2_STAT5 439 442 PF00017 0.437
LIG_SH2_STAT5 458 461 PF00017 0.434
LIG_SH2_STAT5 506 509 PF00017 0.448
LIG_SH2_STAT5 562 565 PF00017 0.448
LIG_SH2_STAT5 640 643 PF00017 0.465
LIG_SH2_STAT5 69 72 PF00017 0.392
LIG_SH2_STAT5 735 738 PF00017 0.534
LIG_SH2_STAT5 849 852 PF00017 0.385
LIG_SH2_STAT5 974 977 PF00017 0.438
LIG_SH3_3 1076 1082 PF00018 0.488
LIG_SH3_3 1339 1345 PF00018 0.448
LIG_SH3_3 1582 1588 PF00018 0.448
LIG_SH3_3 41 47 PF00018 0.602
LIG_SH3_3 900 906 PF00018 0.448
LIG_SUMO_SIM_anti_2 1015 1020 PF11976 0.489
LIG_SUMO_SIM_anti_2 639 645 PF11976 0.472
LIG_SUMO_SIM_par_1 1101 1108 PF11976 0.356
LIG_SUMO_SIM_par_1 1397 1403 PF11976 0.534
LIG_SUMO_SIM_par_1 1550 1556 PF11976 0.448
LIG_SUMO_SIM_par_1 585 590 PF11976 0.473
LIG_SUMO_SIM_par_1 725 731 PF11976 0.534
LIG_TRAF2_1 133 136 PF00917 0.566
LIG_TRAF2_1 1454 1457 PF00917 0.459
LIG_TRAF2_1 282 285 PF00917 0.569
LIG_TRAF2_1 496 499 PF00917 0.459
LIG_TRAF2_1 751 754 PF00917 0.448
LIG_TYR_ITIM 638 643 PF00017 0.262
LIG_UBA3_1 716 723 PF00899 0.316
LIG_WRC_WIRS_1 432 437 PF05994 0.296
LIG_WRC_WIRS_1 572 577 PF05994 0.300
MOD_CDK_SPK_2 1116 1121 PF00069 0.300
MOD_CK1_1 1105 1111 PF00069 0.309
MOD_CK1_1 1129 1135 PF00069 0.300
MOD_CK1_1 1376 1382 PF00069 0.338
MOD_CK1_1 1391 1397 PF00069 0.197
MOD_CK1_1 1417 1423 PF00069 0.316
MOD_CK1_1 1537 1543 PF00069 0.325
MOD_CK1_1 1550 1556 PF00069 0.276
MOD_CK1_1 1578 1584 PF00069 0.390
MOD_CK1_1 1610 1616 PF00069 0.620
MOD_CK1_1 2 8 PF00069 0.590
MOD_CK1_1 20 26 PF00069 0.583
MOD_CK1_1 336 342 PF00069 0.551
MOD_CK1_1 555 561 PF00069 0.312
MOD_CK1_1 590 596 PF00069 0.364
MOD_CK1_1 84 90 PF00069 0.570
MOD_CK1_1 9 15 PF00069 0.587
MOD_CK1_1 918 924 PF00069 0.356
MOD_CK1_1 948 954 PF00069 0.464
MOD_CK2_1 1233 1239 PF00069 0.375
MOD_CK2_1 1293 1299 PF00069 0.405
MOD_CK2_1 13 19 PF00069 0.611
MOD_CK2_1 130 136 PF00069 0.470
MOD_CK2_1 1418 1424 PF00069 0.409
MOD_CK2_1 1451 1457 PF00069 0.302
MOD_CK2_1 1550 1556 PF00069 0.300
MOD_CK2_1 408 414 PF00069 0.543
MOD_CK2_1 469 475 PF00069 0.365
MOD_CK2_1 49 55 PF00069 0.486
MOD_CK2_1 564 570 PF00069 0.316
MOD_CK2_1 595 601 PF00069 0.335
MOD_CK2_1 97 103 PF00069 0.466
MOD_Cter_Amidation 1502 1505 PF01082 0.300
MOD_GlcNHglycan 1107 1110 PF01048 0.411
MOD_GlcNHglycan 1132 1135 PF01048 0.319
MOD_GlcNHglycan 1218 1221 PF01048 0.316
MOD_GlcNHglycan 1327 1330 PF01048 0.355
MOD_GlcNHglycan 1375 1378 PF01048 0.421
MOD_GlcNHglycan 1415 1419 PF01048 0.300
MOD_GlcNHglycan 144 147 PF01048 0.561
MOD_GlcNHglycan 1453 1456 PF01048 0.328
MOD_GlcNHglycan 15 18 PF01048 0.641
MOD_GlcNHglycan 168 173 PF01048 0.523
MOD_GlcNHglycan 241 244 PF01048 0.448
MOD_GlcNHglycan 256 259 PF01048 0.406
MOD_GlcNHglycan 342 345 PF01048 0.484
MOD_GlcNHglycan 420 423 PF01048 0.642
MOD_GlcNHglycan 542 545 PF01048 0.357
MOD_GlcNHglycan 554 557 PF01048 0.232
MOD_GlcNHglycan 589 592 PF01048 0.358
MOD_GlcNHglycan 597 600 PF01048 0.340
MOD_GlcNHglycan 8 11 PF01048 0.667
MOD_GlcNHglycan 853 856 PF01048 0.387
MOD_GSK3_1 1008 1015 PF00069 0.350
MOD_GSK3_1 104 111 PF00069 0.614
MOD_GSK3_1 1064 1071 PF00069 0.355
MOD_GSK3_1 1098 1105 PF00069 0.382
MOD_GSK3_1 1126 1133 PF00069 0.373
MOD_GSK3_1 1204 1211 PF00069 0.385
MOD_GSK3_1 1216 1223 PF00069 0.385
MOD_GSK3_1 13 20 PF00069 0.577
MOD_GSK3_1 138 145 PF00069 0.474
MOD_GSK3_1 1414 1421 PF00069 0.421
MOD_GSK3_1 1483 1490 PF00069 0.300
MOD_GSK3_1 1519 1526 PF00069 0.421
MOD_GSK3_1 1557 1564 PF00069 0.312
MOD_GSK3_1 1606 1613 PF00069 0.552
MOD_GSK3_1 2 9 PF00069 0.595
MOD_GSK3_1 229 236 PF00069 0.589
MOD_GSK3_1 23 30 PF00069 0.613
MOD_GSK3_1 336 343 PF00069 0.483
MOD_GSK3_1 587 594 PF00069 0.313
MOD_GSK3_1 917 924 PF00069 0.370
MOD_LATS_1 33 39 PF00433 0.657
MOD_N-GLC_1 1098 1103 PF02516 0.389
MOD_N-GLC_1 1116 1121 PF02516 0.223
MOD_N-GLC_1 1196 1201 PF02516 0.316
MOD_N-GLC_1 1255 1260 PF02516 0.393
MOD_N-GLC_1 1293 1298 PF02516 0.405
MOD_N-GLC_1 142 147 PF02516 0.605
MOD_N-GLC_1 653 658 PF02516 0.393
MOD_N-GLC_2 690 692 PF02516 0.447
MOD_NEK2_1 102 107 PF00069 0.578
MOD_NEK2_1 1047 1052 PF00069 0.521
MOD_NEK2_1 1148 1153 PF00069 0.390
MOD_NEK2_1 1183 1188 PF00069 0.300
MOD_NEK2_1 13 18 PF00069 0.630
MOD_NEK2_1 130 135 PF00069 0.492
MOD_NEK2_1 1325 1330 PF00069 0.421
MOD_NEK2_1 21 26 PF00069 0.673
MOD_NEK2_1 351 356 PF00069 0.500
MOD_NEK2_1 431 436 PF00069 0.433
MOD_NEK2_1 563 568 PF00069 0.357
MOD_NEK2_1 587 592 PF00069 0.346
MOD_NEK2_1 756 761 PF00069 0.300
MOD_NEK2_1 834 839 PF00069 0.401
MOD_NEK2_1 917 922 PF00069 0.290
MOD_NEK2_1 959 964 PF00069 0.397
MOD_NEK2_2 203 208 PF00069 0.335
MOD_PIKK_1 1132 1138 PF00454 0.300
MOD_PIKK_1 229 235 PF00454 0.544
MOD_PIKK_1 534 540 PF00454 0.316
MOD_PIKK_1 564 570 PF00454 0.447
MOD_PIKK_1 591 597 PF00454 0.421
MOD_PIKK_1 756 762 PF00454 0.300
MOD_PIKK_1 994 1000 PF00454 0.411
MOD_PKA_1 552 558 PF00069 0.300
MOD_PKA_1 97 103 PF00069 0.492
MOD_PKA_2 1239 1245 PF00069 0.368
MOD_PKA_2 138 144 PF00069 0.580
MOD_PKA_2 1391 1397 PF00069 0.286
MOD_PKA_2 3 9 PF00069 0.606
MOD_PKA_2 314 320 PF00069 0.461
MOD_PKA_2 33 39 PF00069 0.730
MOD_PKA_2 552 558 PF00069 0.333
MOD_PKA_2 60 66 PF00069 0.450
MOD_PKA_2 884 890 PF00069 0.300
MOD_PKA_2 948 954 PF00069 0.469
MOD_Plk_1 1047 1053 PF00069 0.546
MOD_Plk_1 1068 1074 PF00069 0.368
MOD_Plk_1 1255 1261 PF00069 0.385
MOD_Plk_1 1293 1299 PF00069 0.397
MOD_Plk_1 1414 1420 PF00069 0.300
MOD_Plk_1 1596 1602 PF00069 0.355
MOD_Plk_1 168 174 PF00069 0.519
MOD_Plk_1 307 313 PF00069 0.481
MOD_Plk_1 333 339 PF00069 0.488
MOD_Plk_1 370 376 PF00069 0.491
MOD_Plk_1 653 659 PF00069 0.361
MOD_Plk_1 84 90 PF00069 0.540
MOD_Plk_2-3 1260 1266 PF00069 0.335
MOD_Plk_2-3 452 458 PF00069 0.544
MOD_Plk_4 1068 1074 PF00069 0.367
MOD_Plk_4 1293 1299 PF00069 0.405
MOD_Plk_4 1331 1337 PF00069 0.373
MOD_Plk_4 1547 1553 PF00069 0.302
MOD_Plk_4 17 23 PF00069 0.716
MOD_Plk_4 333 339 PF00069 0.505
MOD_Plk_4 426 432 PF00069 0.483
MOD_Plk_4 951 957 PF00069 0.496
MOD_ProDKin_1 1008 1014 PF00069 0.421
MOD_ProDKin_1 108 114 PF00069 0.581
MOD_ProDKin_1 1116 1122 PF00069 0.300
MOD_ProDKin_1 1376 1382 PF00069 0.290
MOD_ProDKin_1 233 239 PF00069 0.525
MOD_ProDKin_1 379 385 PF00069 0.386
MOD_ProDKin_1 693 699 PF00069 0.307
MOD_ProDKin_1 710 716 PF00069 0.213
MOD_ProDKin_1 86 92 PF00069 0.346
MOD_ProDKin_1 902 908 PF00069 0.286
MOD_ProDKin_1 923 929 PF00069 0.494
MOD_ProDKin_1 973 979 PF00069 0.352
MOD_SUMO_rev_2 1263 1271 PF00179 0.316
MOD_SUMO_rev_2 1451 1460 PF00179 0.447
MOD_SUMO_rev_2 498 503 PF00179 0.300
MOD_SUMO_rev_2 719 724 PF00179 0.340
TRG_AP2beta_CARGO_1 199 208 PF09066 0.473
TRG_DiLeu_BaEn_1 126 131 PF01217 0.524
TRG_DiLeu_BaEn_1 1516 1521 PF01217 0.300
TRG_DiLeu_BaEn_1 169 174 PF01217 0.408
TRG_DiLeu_BaEn_1 438 443 PF01217 0.386
TRG_DiLeu_BaEn_1 601 606 PF01217 0.335
TRG_DiLeu_BaEn_2 1610 1616 PF01217 0.647
TRG_DiLeu_BaEn_2 199 205 PF01217 0.462
TRG_DiLeu_BaEn_2 894 900 PF01217 0.300
TRG_DiLeu_BaEn_4 364 370 PF01217 0.518
TRG_DiLeu_BaLyEn_6 1529 1534 PF01217 0.300
TRG_DiLeu_BaLyEn_6 583 588 PF01217 0.385
TRG_DiLeu_BaLyEn_6 830 835 PF01217 0.384
TRG_DiLeu_LyEn_5 601 606 PF01217 0.421
TRG_ENDOCYTIC_2 1093 1096 PF00928 0.385
TRG_ENDOCYTIC_2 1166 1169 PF00928 0.300
TRG_ENDOCYTIC_2 1270 1273 PF00928 0.307
TRG_ENDOCYTIC_2 1469 1472 PF00928 0.300
TRG_ENDOCYTIC_2 1491 1494 PF00928 0.421
TRG_ENDOCYTIC_2 152 155 PF00928 0.411
TRG_ENDOCYTIC_2 439 442 PF00928 0.399
TRG_ENDOCYTIC_2 456 459 PF00928 0.184
TRG_ENDOCYTIC_2 506 509 PF00928 0.300
TRG_ENDOCYTIC_2 631 634 PF00928 0.300
TRG_ENDOCYTIC_2 640 643 PF00928 0.300
TRG_ENDOCYTIC_2 676 679 PF00928 0.300
TRG_ENDOCYTIC_2 735 738 PF00928 0.298
TRG_ENDOCYTIC_2 752 755 PF00928 0.236
TRG_ENDOCYTIC_2 866 869 PF00928 0.316
TRG_ENDOCYTIC_2 897 900 PF00928 0.335
TRG_ER_diArg_1 1005 1007 PF00400 0.309
TRG_ER_diArg_1 32 35 PF00400 0.652
TRG_ER_diArg_1 387 389 PF00400 0.474
TRG_ER_diArg_1 681 683 PF00400 0.300
TRG_ER_diArg_1 790 792 PF00400 0.440
TRG_ER_diArg_1 946 949 PF00400 0.515
TRG_ER_diArg_1 987 990 PF00400 0.233
TRG_ER_FFAT_2 72 81 PF00635 0.517
TRG_NES_CRM1_1 1597 1611 PF08389 0.335
TRG_NES_CRM1_1 188 202 PF08389 0.387
TRG_NES_CRM1_1 725 739 PF08389 0.379
TRG_NES_CRM1_1 753 767 PF08389 0.357
TRG_NLS_MonoExtN_4 1502 1508 PF00514 0.300
TRG_NLS_MonoExtN_4 94 100 PF00514 0.539
TRG_Pf-PMV_PEXEL_1 1121 1125 PF00026 0.300
TRG_Pf-PMV_PEXEL_1 1160 1165 PF00026 0.300
TRG_Pf-PMV_PEXEL_1 355 359 PF00026 0.426
TRG_Pf-PMV_PEXEL_1 495 499 PF00026 0.316
TRG_Pf-PMV_PEXEL_1 517 522 PF00026 0.300

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P6L8 Leptomonas seymouri 85% 100%
A0A0N1PFE3 Leptomonas seymouri 25% 100%
A0A0S4JAX3 Bodo saltans 57% 96%
A0A1X0P5I4 Trypanosomatidae 66% 100%
A0A3Q8ICE2 Leishmania donovani 100% 100%
A0A3S7X436 Leishmania donovani 27% 100%
A0A422NX41 Trypanosoma rangeli 64% 100%
A4HEF6 Leishmania braziliensis 92% 100%
A4HIZ1 Leishmania braziliensis 27% 100%
A4I6A8 Leishmania infantum 27% 100%
B8JKD7 Danio rerio 30% 100%
D0A5J5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 59% 100%
E9AXD9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 96% 100%
E9B1G4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 27% 100%
F4I366 Arabidopsis thaliana 28% 100%
O54888 Rattus norvegicus 30% 100%
O74633 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) 32% 100%
P20028 Drosophila melanogaster 30% 100%
P22138 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 31% 100%
P28365 Euplotoides octocarinatus 28% 100%
P70700 Mus musculus 30% 100%
Q4Q6P8 Leishmania major 27% 100%
Q4QA33 Leishmania major 97% 100%
Q54BM1 Dictyostelium discoideum 30% 100%
Q5REE8 Pongo abelii 30% 100%
Q75DS1 Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) 32% 100%
Q9H9Y6 Homo sapiens 31% 100%
Q9P7X8 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 32% 100%
V5B7L4 Trypanosoma cruzi 63% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS