Rx_N domain-containing protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I183_LEIIN

TriTrypDb:

LINF_250009200

Length:

100

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I183

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I183

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	2	6	PF00082	0.529
CLV_PCSK_SKI1_1	35	39	PF00082	0.704
DEG_Nend_UBRbox_1	1	4	PF02207	0.466
DOC_USP7_MATH_1	76	80	PF00917	0.707
DOC_USP7_UBL2_3	2	6	PF12436	0.458
DOC_WW_Pin1_4	17	22	PF00397	0.674
LIG_14-3-3_CanoR_1	58	62	PF00244	0.546
LIG_BRCT_BRCA1_1	38	42	PF00533	0.438
LIG_FHA_1	18	24	PF00498	0.558
LIG_LIR_Gen_1	59	68	PF02991	0.487
LIG_LIR_Nem_3	59	64	PF02991	0.504
LIG_LIR_Nem_3	7	13	PF02991	0.579
LIG_REV1ctd_RIR_1	2	10	PF16727	0.485
LIG_SH2_CRK	10	14	PF00017	0.452
LIG_SH2_CRK	61	65	PF00017	0.525
LIG_SH2_GRB2like	67	70	PF00017	0.573
LIG_SH2_STAT5	67	70	PF00017	0.598
LIG_SH3_3	70	76	PF00018	0.568
LIG_SH3_3	91	97	PF00018	0.605
LIG_TYR_ITIM	8	13	PF00017	0.449
MOD_CK1_1	15	21	PF00069	0.672
MOD_GlcNHglycan	80	83	PF01048	0.561
MOD_NEK2_1	4	9	PF00069	0.480
MOD_PKA_2	57	63	PF00069	0.545
MOD_Plk_4	4	10	PF00069	0.538
MOD_ProDKin_1	17	23	PF00069	0.673
TRG_ENDOCYTIC_2	10	13	PF00928	0.552
TRG_ENDOCYTIC_2	61	64	PF00928	0.506
TRG_Pf-PMV_PEXEL_1	35	40	PF00026	0.474

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7W4	Leptomonas seymouri	36%	90%
A0A3S7WYT9	Leishmania donovani	100%	100%
A4HDY2	Leishmania braziliensis	59%	100%
E9AXB7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%
Q4QA55	Leishmania major	86%	100%