RNA Processing, poly(A)-binding 3 PABP3
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 9 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 8 |
| NetGPI | no | yes: 0, no: 8 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005634 | nucleus | 5 | 1 |
| GO:0005737 | cytoplasm | 2 | 1 |
| GO:0005829 | cytosol | 2 | 1 |
| GO:0032991 | protein-containing complex | 1 | 1 |
| GO:0043226 | organelle | 2 | 1 |
| GO:0043227 | membrane-bounded organelle | 3 | 1 |
| GO:0043229 | intracellular organelle | 3 | 1 |
| GO:0043231 | intracellular membrane-bounded organelle | 4 | 1 |
| GO:0110165 | cellular anatomical entity | 1 | 1 |
| GO:1990904 | ribonucleoprotein complex | 2 | 1 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pescher et al. (upgregulation) | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
|
Lahav et al. - mRNA
- Protein
|
Related structures:
AlphaFold database: A4I150
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0003676 | nucleic acid binding | 3 | 9 |
| GO:0003723 | RNA binding | 4 | 9 |
| GO:0005488 | binding | 1 | 9 |
| GO:0097159 | organic cyclic compound binding | 2 | 9 |
| GO:1901363 | heterocyclic compound binding | 2 | 9 |
| GO:0003727 | single-stranded RNA binding | 5 | 1 |
| GO:0003729 | mRNA binding | 5 | 1 |
| GO:0003730 | mRNA 3'-UTR binding | 6 | 1 |
| GO:0005515 | protein binding | 2 | 1 |
| GO:0008143 | poly(A) binding | 7 | 1 |
| GO:0008187 | poly-pyrimidine tract binding | 6 | 1 |
| GO:0008266 | poly(U) RNA binding | 7 | 1 |
| GO:0031369 | translation initiation factor binding | 3 | 1 |
| GO:0031370 | eukaryotic initiation factor 4G binding | 4 | 1 |
| GO:0070717 | poly-purine tract binding | 6 | 1 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_C14_Caspase3-7 | 60 | 64 | PF00656 | 0.438 |
| CLV_NRD_NRD_1 | 175 | 177 | PF00675 | 0.381 |
| CLV_NRD_NRD_1 | 379 | 381 | PF00675 | 0.479 |
| CLV_NRD_NRD_1 | 433 | 435 | PF00675 | 0.551 |
| CLV_NRD_NRD_1 | 93 | 95 | PF00675 | 0.364 |
| CLV_PCSK_KEX2_1 | 175 | 177 | PF00082 | 0.439 |
| CLV_PCSK_KEX2_1 | 379 | 381 | PF00082 | 0.478 |
| CLV_PCSK_KEX2_1 | 433 | 435 | PF00082 | 0.551 |
| CLV_PCSK_SKI1_1 | 129 | 133 | PF00082 | 0.213 |
| CLV_PCSK_SKI1_1 | 153 | 157 | PF00082 | 0.206 |
| CLV_PCSK_SKI1_1 | 228 | 232 | PF00082 | 0.243 |
| CLV_PCSK_SKI1_1 | 258 | 262 | PF00082 | 0.506 |
| CLV_PCSK_SKI1_1 | 306 | 310 | PF00082 | 0.246 |
| CLV_PCSK_SKI1_1 | 83 | 87 | PF00082 | 0.357 |
| CLV_Separin_Metazoa | 445 | 449 | PF03568 | 0.612 |
| DEG_ODPH_VHL_1 | 76 | 88 | PF01847 | 0.342 |
| DOC_CYCLIN_RxL_1 | 490 | 500 | PF00134 | 0.430 |
| DOC_MAPK_gen_1 | 210 | 219 | PF00069 | 0.413 |
| DOC_MAPK_MEF2A_6 | 504 | 512 | PF00069 | 0.379 |
| DOC_PP1_RVXF_1 | 81 | 87 | PF00149 | 0.301 |
| DOC_PP4_MxPP_1 | 389 | 392 | PF00568 | 0.542 |
| DOC_PP4_MxPP_1 | 408 | 411 | PF00568 | 0.607 |
| DOC_PP4_MxPP_1 | 412 | 415 | PF00568 | 0.603 |
| DOC_PP4_MxPP_1 | 447 | 450 | PF00568 | 0.634 |
| DOC_USP7_MATH_1 | 131 | 135 | PF00917 | 0.469 |
| DOC_USP7_MATH_1 | 183 | 187 | PF00917 | 0.402 |
| DOC_USP7_MATH_1 | 345 | 349 | PF00917 | 0.459 |
| DOC_USP7_MATH_1 | 35 | 39 | PF00917 | 0.403 |
| DOC_USP7_MATH_1 | 496 | 500 | PF00917 | 0.446 |
| DOC_WW_Pin1_4 | 475 | 480 | PF00397 | 0.403 |
| LIG_14-3-3_CanoR_1 | 124 | 132 | PF00244 | 0.435 |
| LIG_14-3-3_CanoR_1 | 339 | 349 | PF00244 | 0.424 |
| LIG_14-3-3_CanoR_1 | 452 | 456 | PF00244 | 0.572 |
| LIG_14-3-3_CanoR_1 | 7 | 11 | PF00244 | 0.275 |
| LIG_Actin_WH2_2 | 293 | 308 | PF00022 | 0.433 |
| LIG_Clathr_ClatBox_1 | 231 | 235 | PF01394 | 0.398 |
| LIG_CtBP_PxDLS_1 | 418 | 422 | PF00389 | 0.612 |
| LIG_FHA_1 | 504 | 510 | PF00498 | 0.379 |
| LIG_FHA_2 | 198 | 204 | PF00498 | 0.380 |
| LIG_FHA_2 | 58 | 64 | PF00498 | 0.446 |
| LIG_LIR_Gen_1 | 227 | 234 | PF02991 | 0.464 |
| LIG_LIR_Gen_1 | 488 | 497 | PF02991 | 0.379 |
| LIG_LIR_Gen_1 | 515 | 526 | PF02991 | 0.446 |
| LIG_LIR_Nem_3 | 138 | 144 | PF02991 | 0.379 |
| LIG_LIR_Nem_3 | 186 | 190 | PF02991 | 0.292 |
| LIG_LIR_Nem_3 | 209 | 214 | PF02991 | 0.414 |
| LIG_LIR_Nem_3 | 227 | 232 | PF02991 | 0.403 |
| LIG_LIR_Nem_3 | 307 | 312 | PF02991 | 0.381 |
| LIG_LIR_Nem_3 | 327 | 331 | PF02991 | 0.364 |
| LIG_LIR_Nem_3 | 488 | 494 | PF02991 | 0.379 |
| LIG_LIR_Nem_3 | 50 | 56 | PF02991 | 0.379 |
| LIG_LIR_Nem_3 | 515 | 521 | PF02991 | 0.446 |
| LIG_LIR_Nem_3 | 523 | 528 | PF02991 | 0.446 |
| LIG_NRBOX | 485 | 491 | PF00104 | 0.446 |
| LIG_Pex14_2 | 225 | 229 | PF04695 | 0.463 |
| LIG_Pex14_2 | 396 | 400 | PF04695 | 0.562 |
| LIG_SH2_CRK | 141 | 145 | PF00017 | 0.402 |
| LIG_SH2_CRK | 453 | 457 | PF00017 | 0.544 |
| LIG_SH2_CRK | 491 | 495 | PF00017 | 0.403 |
| LIG_SH2_CRK | 53 | 57 | PF00017 | 0.379 |
| LIG_SH2_CRK | 73 | 77 | PF00017 | 0.336 |
| LIG_SH2_GRB2like | 284 | 287 | PF00017 | 0.477 |
| LIG_SH2_GRB2like | 55 | 58 | PF00017 | 0.379 |
| LIG_SH2_SRC | 284 | 287 | PF00017 | 0.477 |
| LIG_SH2_STAP1 | 491 | 495 | PF00017 | 0.446 |
| LIG_SH2_STAT3 | 460 | 463 | PF00017 | 0.707 |
| LIG_SH2_STAT5 | 11 | 14 | PF00017 | 0.364 |
| LIG_SH2_STAT5 | 191 | 194 | PF00017 | 0.379 |
| LIG_SH2_STAT5 | 292 | 295 | PF00017 | 0.379 |
| LIG_SH2_STAT5 | 362 | 365 | PF00017 | 0.336 |
| LIG_SH2_STAT5 | 453 | 456 | PF00017 | 0.569 |
| LIG_SH2_STAT5 | 473 | 476 | PF00017 | 0.309 |
| LIG_SH2_STAT5 | 485 | 488 | PF00017 | 0.446 |
| LIG_SH2_STAT5 | 55 | 58 | PF00017 | 0.379 |
| LIG_SH2_STAT5 | 73 | 76 | PF00017 | 0.427 |
| LIG_SH3_3 | 166 | 172 | PF00018 | 0.453 |
| LIG_SH3_3 | 398 | 404 | PF00018 | 0.517 |
| LIG_SH3_3 | 408 | 414 | PF00018 | 0.481 |
| LIG_SH3_3 | 443 | 449 | PF00018 | 0.534 |
| LIG_Sin3_3 | 260 | 267 | PF02671 | 0.272 |
| LIG_TRAF2_1 | 233 | 236 | PF00917 | 0.430 |
| LIG_TRAF2_1 | 513 | 516 | PF00917 | 0.446 |
| LIG_TRAF2_2 | 462 | 467 | PF00917 | 0.540 |
| LIG_TYR_ITIM | 489 | 494 | PF00017 | 0.446 |
| LIG_TYR_ITIM | 51 | 56 | PF00017 | 0.379 |
| LIG_TYR_ITIM | 71 | 76 | PF00017 | 0.286 |
| MOD_CK1_1 | 250 | 256 | PF00069 | 0.575 |
| MOD_CK1_1 | 475 | 481 | PF00069 | 0.439 |
| MOD_CK2_1 | 266 | 272 | PF00069 | 0.491 |
| MOD_CK2_1 | 361 | 367 | PF00069 | 0.390 |
| MOD_CK2_1 | 510 | 516 | PF00069 | 0.446 |
| MOD_GlcNHglycan | 133 | 136 | PF01048 | 0.198 |
| MOD_GlcNHglycan | 251 | 255 | PF01048 | 0.476 |
| MOD_GlcNHglycan | 342 | 345 | PF01048 | 0.236 |
| MOD_GlcNHglycan | 427 | 430 | PF01048 | 0.587 |
| MOD_GlcNHglycan | 95 | 98 | PF01048 | 0.439 |
| MOD_GSK3_1 | 131 | 138 | PF00069 | 0.469 |
| MOD_GSK3_1 | 213 | 220 | PF00069 | 0.367 |
| MOD_N-GLC_1 | 158 | 163 | PF02516 | 0.181 |
| MOD_N-GLC_1 | 247 | 252 | PF02516 | 0.246 |
| MOD_N-GLC_1 | 324 | 329 | PF02516 | 0.233 |
| MOD_N-GLC_1 | 71 | 76 | PF02516 | 0.179 |
| MOD_NEK2_1 | 158 | 163 | PF00069 | 0.430 |
| MOD_NEK2_1 | 29 | 34 | PF00069 | 0.385 |
| MOD_NEK2_1 | 354 | 359 | PF00069 | 0.523 |
| MOD_NEK2_1 | 361 | 366 | PF00069 | 0.300 |
| MOD_NEK2_1 | 489 | 494 | PF00069 | 0.446 |
| MOD_NEK2_1 | 497 | 502 | PF00069 | 0.446 |
| MOD_NEK2_1 | 71 | 76 | PF00069 | 0.433 |
| MOD_NEK2_2 | 183 | 188 | PF00069 | 0.383 |
| MOD_NEK2_2 | 324 | 329 | PF00069 | 0.398 |
| MOD_NEK2_2 | 35 | 40 | PF00069 | 0.389 |
| MOD_OFUCOSY | 122 | 128 | PF10250 | 0.246 |
| MOD_PIKK_1 | 44 | 50 | PF00454 | 0.379 |
| MOD_PIKK_1 | 451 | 457 | PF00454 | 0.574 |
| MOD_PKA_2 | 451 | 457 | PF00069 | 0.645 |
| MOD_PKA_2 | 6 | 12 | PF00069 | 0.287 |
| MOD_PKA_2 | 93 | 99 | PF00069 | 0.437 |
| MOD_Plk_2-3 | 298 | 304 | PF00069 | 0.446 |
| MOD_Plk_4 | 213 | 219 | PF00069 | 0.418 |
| MOD_Plk_4 | 279 | 285 | PF00069 | 0.474 |
| MOD_Plk_4 | 6 | 12 | PF00069 | 0.282 |
| MOD_ProDKin_1 | 475 | 481 | PF00069 | 0.403 |
| MOD_SUMO_rev_2 | 201 | 207 | PF00179 | 0.405 |
| MOD_SUMO_rev_2 | 271 | 280 | PF00179 | 0.453 |
| MOD_SUMO_rev_2 | 298 | 305 | PF00179 | 0.382 |
| MOD_SUMO_rev_2 | 364 | 371 | PF00179 | 0.414 |
| TRG_DiLeu_BaEn_3 | 515 | 521 | PF01217 | 0.398 |
| TRG_DiLeu_BaLyEn_6 | 371 | 376 | PF01217 | 0.510 |
| TRG_ENDOCYTIC_2 | 141 | 144 | PF00928 | 0.402 |
| TRG_ENDOCYTIC_2 | 491 | 494 | PF00928 | 0.403 |
| TRG_ENDOCYTIC_2 | 53 | 56 | PF00928 | 0.379 |
| TRG_ENDOCYTIC_2 | 73 | 76 | PF00928 | 0.335 |
| TRG_ER_diArg_1 | 174 | 176 | PF00400 | 0.423 |
| TRG_ER_diArg_1 | 371 | 374 | PF00400 | 0.479 |
| TRG_ER_diArg_1 | 432 | 434 | PF00400 | 0.548 |
| TRG_Pf-PMV_PEXEL_1 | 306 | 310 | PF00026 | 0.261 |
| TRG_Pf-PMV_PEXEL_1 | 347 | 352 | PF00026 | 0.198 |
| TRG_Pf-PMV_PEXEL_1 | 374 | 378 | PF00026 | 0.455 |
| TRG_Pf-PMV_PEXEL_1 | 493 | 498 | PF00026 | 0.198 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N0P3Y8 | Leptomonas seymouri | 39% | 96% |
| A0A0N1I0F0 | Leptomonas seymouri | 77% | 99% |
| A0A0S4IKZ4 | Bodo saltans | 35% | 95% |
| A0A0S4JPT3 | Bodo saltans | 48% | 96% |
| A0A1X0P4T3 | Trypanosomatidae | 35% | 97% |
| A0A1X0P4V5 | Trypanosomatidae | 45% | 95% |
| A0A1X0P525 | Trypanosomatidae | 35% | 99% |
| A0A3Q8IF40 | Leishmania donovani | 99% | 100% |
| A0A3Q8IGR8 | Leishmania donovani | 38% | 97% |
| A0A3Q8IMW2 | Leishmania donovani | 35% | 93% |
| A0A3R7NAH9 | Trypanosoma rangeli | 39% | 100% |
| A0A422NK82 | Trypanosoma rangeli | 36% | 99% |
| A1D4K4 | Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) | 37% | 72% |
| A2Q848 | Aspergillus niger (strain CBS 513.88 / FGSC A1513) | 25% | 74% |
| A3LXL0 | Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) | 35% | 86% |
| A4HDV5 | Leishmania braziliensis | 84% | 100% |
| A4HN85 | Leishmania braziliensis | 35% | 100% |
| A4HNG6 | Leishmania braziliensis | 34% | 100% |
| A4IBV3 | Leishmania infantum | 35% | 93% |
| A4IC57 | Leishmania infantum | 38% | 97% |
| A5DM21 | Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) | 36% | 86% |
| A5DW14 | Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) | 36% | 82% |
| C9ZYE6 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 33% | 96% |
| C9ZYQ8 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 35% | 98% |
| E9AFP0 | Leishmania major | 36% | 100% |
| E9AFX7 | Leishmania major | 35% | 100% |
| E9AX84 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 93% | 100% |
| E9B6U3 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 36% | 100% |
| E9B730 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 34% | 100% |
| F1QB54 | Danio rerio | 42% | 86% |
| F4HT49 | Arabidopsis thaliana | 38% | 100% |
| O04319 | Arabidopsis thaliana | 34% | 100% |
| O22173 | Arabidopsis thaliana | 38% | 82% |
| O60176 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 24% | 100% |
| O64380 | Arabidopsis thaliana | 38% | 82% |
| P04147 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 37% | 94% |
| P09405 | Mus musculus | 23% | 77% |
| P0CB38 | Homo sapiens | 39% | 100% |
| P0CP46 | Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) | 35% | 81% |
| P0CP47 | Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) | 35% | 81% |
| P11940 | Homo sapiens | 37% | 86% |
| P19338 | Homo sapiens | 21% | 77% |
| P20965 | Xenopus laevis | 36% | 86% |
| P21187 | Drosophila melanogaster | 43% | 86% |
| P29341 | Mus musculus | 37% | 86% |
| P31209 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 39% | 83% |
| P42731 | Arabidopsis thaliana | 38% | 86% |
| P60047 | Gorilla gorilla gorilla | 34% | 100% |
| P60048 | Hylobates lar | 34% | 100% |
| P60049 | Pan troglodytes | 34% | 100% |
| P60050 | Pongo pygmaeus | 34% | 100% |
| P61286 | Bos taurus | 37% | 86% |
| Q05196 | Arabidopsis thaliana | 35% | 80% |
| Q0CR95 | Aspergillus terreus (strain NIH 2624 / FGSC A1156) | 36% | 72% |
| Q0U1G2 | Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) | 37% | 73% |
| Q13310 | Homo sapiens | 41% | 84% |
| Q1DXH0 | Coccidioides immitis (strain RS) | 34% | 71% |
| Q1ZXC2 | Dictyostelium discoideum | 32% | 67% |
| Q2GSX8 | Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) | 37% | 69% |
| Q4P8R9 | Ustilago maydis (strain 521 / FGSC 9021) | 35% | 84% |
| Q4QA88 | Leishmania major | 95% | 100% |
| Q4R4J7 | Macaca fascicularis | 21% | 77% |
| Q4VXU2 | Homo sapiens | 35% | 89% |
| Q4WK03 | Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) | 37% | 72% |
| Q54BM2 | Dictyostelium discoideum | 35% | 96% |
| Q5AI15 | Candida albicans (strain SC5314 / ATCC MYA-2876) | 37% | 86% |
| Q5B630 | Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) | 37% | 74% |
| Q5R8F7 | Pongo abelii | 37% | 86% |
| Q5RF26 | Pongo abelii | 21% | 76% |
| Q6BI95 | Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) | 37% | 87% |
| Q6CDH3 | Yarrowia lipolytica (strain CLIB 122 / E 150) | 38% | 86% |
| Q6CSV3 | Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) | 37% | 92% |
| Q6DEY7 | Xenopus tropicalis | 35% | 86% |
| Q6FKG4 | Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) | 36% | 94% |
| Q6GR16 | Xenopus laevis | 42% | 86% |
| Q6IP09 | Xenopus laevis | 36% | 86% |
| Q74ZS6 | Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) | 36% | 93% |
| Q7JGR2 | Macaca mulatta | 34% | 100% |
| Q7S6N6 | Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) | 33% | 71% |
| Q8SR30 | Encephalitozoon cuniculi (strain GB-M1) | 31% | 100% |
| Q96DU9 | Homo sapiens | 34% | 100% |
| Q98SP8 | Xenopus laevis | 39% | 86% |
| Q9EPH8 | Rattus norvegicus | 36% | 86% |
| Q9FXA2 | Arabidopsis thaliana | 41% | 81% |
| Q9H361 | Homo sapiens | 35% | 86% |
| Q9ZQA8 | Arabidopsis thaliana | 33% | 89% |
| V5BYR2 | Trypanosoma cruzi | 35% | 96% |
| V5DUJ1 | Trypanosoma cruzi | 35% | 99% |