LeishMANIAdb
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Putative pre-mRNA splicing factor

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative pre-mRNA splicing factor
Gene product:
pre-mRNA-splicing factor ATP-dependent RNA helicase - putative
Species:
Leishmania infantum
UniProt:
A4I0U7_LEIIN
TriTrypDb:
LINF_240016200
Length:
1086

Annotations

Annotations by Jardim et al.

RNA Processing, pre-mRNA splicing factor

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 12
NetGPI no yes: 0, no: 12
Cellular components
Term Name Level Count
GO:0005681 spliceosomal complex 3 1
GO:0032991 protein-containing complex 1 1
GO:0140513 nuclear protein-containing complex 2 1
GO:1990904 ribonucleoprotein complex 2 1

Expansion

Sequence features

A4I0U7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I0U7

Function

Biological processes
Term Name Level Count
GO:0000375 RNA splicing, via transesterification reactions 8 1
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 9 1
GO:0000398 mRNA splicing, via spliceosome 8 1
GO:0006139 nucleobase-containing compound metabolic process 3 1
GO:0006396 RNA processing 6 1
GO:0006397 mRNA processing 7 1
GO:0006725 cellular aromatic compound metabolic process 3 1
GO:0006807 nitrogen compound metabolic process 2 1
GO:0008152 metabolic process 1 1
GO:0008380 RNA splicing 7 1
GO:0009987 cellular process 1 1
GO:0016070 RNA metabolic process 5 1
GO:0016071 mRNA metabolic process 6 1
GO:0034641 cellular nitrogen compound metabolic process 3 1
GO:0043170 macromolecule metabolic process 3 1
GO:0044237 cellular metabolic process 2 1
GO:0044238 primary metabolic process 2 1
GO:0046483 heterocycle metabolic process 3 1
GO:0071704 organic substance metabolic process 2 1
GO:0090304 nucleic acid metabolic process 4 1
GO:1901360 organic cyclic compound metabolic process 3 1
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 13
GO:0004386 helicase activity 2 13
GO:0140640 catalytic activity, acting on a nucleic acid 2 13
GO:0140657 ATP-dependent activity 1 13
GO:0000166 nucleotide binding 3 11
GO:0003676 nucleic acid binding 3 7
GO:0003723 RNA binding 4 1
GO:0005488 binding 1 11
GO:0005524 ATP binding 5 11
GO:0016787 hydrolase activity 2 11
GO:0017076 purine nucleotide binding 4 11
GO:0030554 adenyl nucleotide binding 5 11
GO:0032553 ribonucleotide binding 3 11
GO:0032555 purine ribonucleotide binding 4 11
GO:0032559 adenyl ribonucleotide binding 5 11
GO:0035639 purine ribonucleoside triphosphate binding 4 11
GO:0036094 small molecule binding 2 11
GO:0043167 ion binding 2 11
GO:0043168 anion binding 3 11
GO:0097159 organic cyclic compound binding 2 11
GO:0097367 carbohydrate derivative binding 2 11
GO:1901265 nucleoside phosphate binding 3 11
GO:1901363 heterocyclic compound binding 2 11

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 109 113 PF00656 0.547
CLV_C14_Caspase3-7 364 368 PF00656 0.584
CLV_C14_Caspase3-7 741 745 PF00656 0.365
CLV_C14_Caspase3-7 762 766 PF00656 0.506
CLV_MEL_PAP_1 438 444 PF00089 0.359
CLV_NRD_NRD_1 1082 1084 PF00675 0.560
CLV_NRD_NRD_1 118 120 PF00675 0.621
CLV_NRD_NRD_1 146 148 PF00675 0.566
CLV_NRD_NRD_1 165 167 PF00675 0.407
CLV_NRD_NRD_1 276 278 PF00675 0.713
CLV_NRD_NRD_1 335 337 PF00675 0.514
CLV_NRD_NRD_1 348 350 PF00675 0.340
CLV_NRD_NRD_1 365 367 PF00675 0.489
CLV_NRD_NRD_1 370 372 PF00675 0.514
CLV_NRD_NRD_1 431 433 PF00675 0.400
CLV_NRD_NRD_1 440 442 PF00675 0.384
CLV_NRD_NRD_1 519 521 PF00675 0.384
CLV_NRD_NRD_1 534 536 PF00675 0.386
CLV_NRD_NRD_1 610 612 PF00675 0.218
CLV_NRD_NRD_1 650 652 PF00675 0.250
CLV_NRD_NRD_1 704 706 PF00675 0.215
CLV_NRD_NRD_1 906 908 PF00675 0.470
CLV_NRD_NRD_1 938 940 PF00675 0.265
CLV_NRD_NRD_1 942 944 PF00675 0.272
CLV_PCSK_KEX2_1 1081 1083 PF00082 0.577
CLV_PCSK_KEX2_1 11 13 PF00082 0.652
CLV_PCSK_KEX2_1 146 148 PF00082 0.525
CLV_PCSK_KEX2_1 165 167 PF00082 0.407
CLV_PCSK_KEX2_1 212 214 PF00082 0.417
CLV_PCSK_KEX2_1 276 278 PF00082 0.708
CLV_PCSK_KEX2_1 335 337 PF00082 0.511
CLV_PCSK_KEX2_1 365 367 PF00082 0.466
CLV_PCSK_KEX2_1 370 372 PF00082 0.502
CLV_PCSK_KEX2_1 431 433 PF00082 0.412
CLV_PCSK_KEX2_1 440 442 PF00082 0.396
CLV_PCSK_KEX2_1 518 520 PF00082 0.381
CLV_PCSK_KEX2_1 609 611 PF00082 0.219
CLV_PCSK_KEX2_1 938 940 PF00082 0.265
CLV_PCSK_KEX2_1 942 944 PF00082 0.274
CLV_PCSK_PC1ET2_1 1081 1083 PF00082 0.617
CLV_PCSK_PC1ET2_1 11 13 PF00082 0.640
CLV_PCSK_PC1ET2_1 212 214 PF00082 0.420
CLV_PCSK_PC7_1 366 372 PF00082 0.560
CLV_PCSK_PC7_1 938 944 PF00082 0.206
CLV_PCSK_SKI1_1 1072 1076 PF00082 0.665
CLV_PCSK_SKI1_1 471 475 PF00082 0.335
CLV_PCSK_SKI1_1 514 518 PF00082 0.454
CLV_PCSK_SKI1_1 809 813 PF00082 0.270
CLV_PCSK_SKI1_1 835 839 PF00082 0.243
CLV_PCSK_SKI1_1 948 952 PF00082 0.226
CLV_Separin_Metazoa 384 388 PF03568 0.335
DEG_APCC_DBOX_1 519 527 PF00400 0.308
DEG_APCC_DBOX_1 608 616 PF00400 0.432
DEG_Nend_UBRbox_2 1 3 PF02207 0.708
DEG_SPOP_SBC_1 1013 1017 PF00917 0.463
DEG_SPOP_SBC_1 1028 1032 PF00917 0.624
DOC_ANK_TNKS_1 431 438 PF00023 0.352
DOC_CYCLIN_RxL_1 287 298 PF00134 0.571
DOC_CYCLIN_RxL_1 806 814 PF00134 0.482
DOC_CYCLIN_yCln2_LP_2 581 587 PF00134 0.348
DOC_CYCLIN_yCln2_LP_2 799 805 PF00134 0.415
DOC_MAPK_gen_1 117 127 PF00069 0.469
DOC_MAPK_gen_1 370 378 PF00069 0.430
DOC_MAPK_gen_1 431 438 PF00069 0.401
DOC_MAPK_gen_1 518 527 PF00069 0.362
DOC_MAPK_gen_1 905 913 PF00069 0.374
DOC_MAPK_HePTP_8 515 527 PF00069 0.444
DOC_MAPK_MEF2A_6 117 125 PF00069 0.470
DOC_MAPK_MEF2A_6 180 188 PF00069 0.497
DOC_MAPK_MEF2A_6 518 527 PF00069 0.362
DOC_MAPK_MEF2A_6 575 583 PF00069 0.316
DOC_MAPK_MEF2A_6 588 595 PF00069 0.426
DOC_MAPK_MEF2A_6 905 913 PF00069 0.429
DOC_MAPK_NFAT4_5 520 528 PF00069 0.316
DOC_PP1_RVXF_1 467 473 PF00149 0.470
DOC_PP2B_LxvP_1 581 584 PF13499 0.486
DOC_PP4_FxxP_1 838 841 PF00568 0.415
DOC_USP7_MATH_1 1044 1048 PF00917 0.629
DOC_USP7_MATH_1 1053 1057 PF00917 0.678
DOC_USP7_MATH_1 106 110 PF00917 0.557
DOC_USP7_MATH_1 189 193 PF00917 0.399
DOC_USP7_MATH_1 24 28 PF00917 0.547
DOC_USP7_MATH_1 660 664 PF00917 0.459
DOC_USP7_MATH_1 73 77 PF00917 0.545
DOC_USP7_MATH_1 91 95 PF00917 0.581
DOC_USP7_MATH_1 912 916 PF00917 0.436
DOC_USP7_MATH_1 937 941 PF00917 0.430
DOC_USP7_UBL2_3 1067 1071 PF12436 0.577
DOC_USP7_UBL2_3 842 846 PF12436 0.517
DOC_WW_Pin1_4 1029 1034 PF00397 0.752
DOC_WW_Pin1_4 1046 1051 PF00397 0.658
DOC_WW_Pin1_4 15 20 PF00397 0.727
DOC_WW_Pin1_4 558 563 PF00397 0.430
DOC_WW_Pin1_4 613 618 PF00397 0.517
DOC_WW_Pin1_4 643 648 PF00397 0.477
DOC_WW_Pin1_4 801 806 PF00397 0.521
DOC_WW_Pin1_4 886 891 PF00397 0.418
LIG_14-3-3_CanoR_1 1043 1053 PF00244 0.611
LIG_14-3-3_CanoR_1 180 188 PF00244 0.477
LIG_14-3-3_CanoR_1 41 48 PF00244 0.531
LIG_14-3-3_CanoR_1 708 718 PF00244 0.525
LIG_14-3-3_CanoR_1 719 726 PF00244 0.369
LIG_14-3-3_CanoR_1 740 744 PF00244 0.433
LIG_14-3-3_CanoR_1 773 777 PF00244 0.343
LIG_14-3-3_CanoR_1 938 944 PF00244 0.442
LIG_Actin_WH2_2 466 482 PF00022 0.322
LIG_Actin_WH2_2 501 516 PF00022 0.374
LIG_Actin_WH2_2 636 653 PF00022 0.382
LIG_BIR_III_2 2 6 PF00653 0.590
LIG_BIR_III_2 644 648 PF00653 0.501
LIG_BIR_III_2 765 769 PF00653 0.485
LIG_BRCT_BRCA1_1 537 541 PF00533 0.351
LIG_BRCT_BRCA1_1 773 777 PF00533 0.424
LIG_eIF4E_1 602 608 PF01652 0.482
LIG_EVH1_2 129 133 PF00568 0.414
LIG_FHA_1 139 145 PF00498 0.470
LIG_FHA_1 179 185 PF00498 0.547
LIG_FHA_1 231 237 PF00498 0.530
LIG_FHA_1 393 399 PF00498 0.398
LIG_FHA_1 404 410 PF00498 0.356
LIG_FHA_1 472 478 PF00498 0.339
LIG_FHA_1 504 510 PF00498 0.350
LIG_FHA_1 529 535 PF00498 0.355
LIG_FHA_1 551 557 PF00498 0.438
LIG_FHA_1 57 63 PF00498 0.738
LIG_FHA_1 602 608 PF00498 0.458
LIG_FHA_1 620 626 PF00498 0.426
LIG_FHA_1 868 874 PF00498 0.358
LIG_FHA_1 919 925 PF00498 0.475
LIG_FHA_2 205 211 PF00498 0.448
LIG_FHA_2 218 224 PF00498 0.495
LIG_FHA_2 353 359 PF00498 0.595
LIG_FHA_2 462 468 PF00498 0.384
LIG_FHA_2 480 486 PF00498 0.281
LIG_FHA_2 594 600 PF00498 0.422
LIG_FHA_2 62 68 PF00498 0.592
LIG_FHA_2 981 987 PF00498 0.415
LIG_FHA_2 990 996 PF00498 0.415
LIG_FXI_DFP_1 758 762 PF00024 0.299
LIG_Integrin_RGD_1 520 522 PF01839 0.478
LIG_Integrin_RGD_TGFB_3 520 526 PF01839 0.447
LIG_LIR_Gen_1 489 499 PF02991 0.328
LIG_LIR_Gen_1 760 769 PF02991 0.335
LIG_LIR_Gen_1 897 906 PF02991 0.448
LIG_LIR_Gen_1 986 994 PF02991 0.420
LIG_LIR_Nem_3 489 494 PF02991 0.339
LIG_LIR_Nem_3 716 721 PF02991 0.479
LIG_LIR_Nem_3 897 902 PF02991 0.453
LIG_LIR_Nem_3 941 947 PF02991 0.432
LIG_MLH1_MIPbox_1 537 541 PF16413 0.351
LIG_NRBOX 231 237 PF00104 0.519
LIG_NRBOX 619 625 PF00104 0.426
LIG_NRBOX 806 812 PF00104 0.517
LIG_PCNA_yPIPBox_3 41 52 PF02747 0.561
LIG_Pex14_1 780 784 PF04695 0.523
LIG_Pex14_2 537 541 PF04695 0.351
LIG_PTAP_UEV_1 1049 1054 PF05743 0.545
LIG_SH2_CRK 491 495 PF00017 0.300
LIG_SH2_CRK 947 951 PF00017 0.450
LIG_SH2_GRB2like 856 859 PF00017 0.425
LIG_SH2_NCK_1 547 551 PF00017 0.344
LIG_SH2_SRC 547 550 PF00017 0.331
LIG_SH2_SRC 872 875 PF00017 0.425
LIG_SH2_STAP1 456 460 PF00017 0.344
LIG_SH2_STAP1 491 495 PF00017 0.300
LIG_SH2_STAP1 726 730 PF00017 0.482
LIG_SH2_STAT3 412 415 PF00017 0.387
LIG_SH2_STAT5 288 291 PF00017 0.602
LIG_SH2_STAT5 388 391 PF00017 0.430
LIG_SH2_STAT5 412 415 PF00017 0.376
LIG_SH2_STAT5 568 571 PF00017 0.343
LIG_SH2_STAT5 671 674 PF00017 0.450
LIG_SH2_STAT5 721 724 PF00017 0.352
LIG_SH2_STAT5 79 82 PF00017 0.619
LIG_SH2_STAT5 872 875 PF00017 0.442
LIG_SH2_STAT5 974 977 PF00017 0.409
LIG_SH2_STAT5 987 990 PF00017 0.415
LIG_SH3_3 1047 1053 PF00018 0.714
LIG_SH3_3 124 130 PF00018 0.582
LIG_SH3_3 480 486 PF00018 0.341
LIG_SH3_3 679 685 PF00018 0.415
LIG_SH3_3 799 805 PF00018 0.450
LIG_SH3_3 906 912 PF00018 0.337
LIG_SH3_5 564 568 PF00018 0.382
LIG_Sin3_3 808 815 PF02671 0.421
LIG_SUMO_SIM_anti_2 181 188 PF11976 0.471
LIG_SUMO_SIM_anti_2 391 398 PF11976 0.430
LIG_SUMO_SIM_anti_2 621 627 PF11976 0.416
LIG_SUMO_SIM_anti_2 744 752 PF11976 0.293
LIG_SUMO_SIM_anti_2 859 867 PF11976 0.426
LIG_SUMO_SIM_par_1 121 126 PF11976 0.405
LIG_SUMO_SIM_par_1 394 401 PF11976 0.505
LIG_SUMO_SIM_par_1 492 498 PF11976 0.318
LIG_SUMO_SIM_par_1 621 627 PF11976 0.406
LIG_SUMO_SIM_par_1 744 752 PF11976 0.302
LIG_SUMO_SIM_par_1 986 992 PF11976 0.426
LIG_TRAF2_1 105 108 PF00917 0.599
LIG_TRAF2_1 330 333 PF00917 0.720
LIG_TRAF2_1 34 37 PF00917 0.467
LIG_TYR_ITIM 975 980 PF00017 0.254
LIG_UBA3_1 509 514 PF00899 0.351
LIG_UBA3_1 837 842 PF00899 0.254
LIG_UBA3_1 902 908 PF00899 0.354
LIG_WRC_WIRS_1 269 274 PF05994 0.570
MOD_CK1_1 1015 1021 PF00069 0.638
MOD_CK1_1 1039 1045 PF00069 0.700
MOD_CK1_1 1048 1054 PF00069 0.685
MOD_CK1_1 1056 1062 PF00069 0.695
MOD_CK1_1 131 137 PF00069 0.514
MOD_CK1_1 142 148 PF00069 0.464
MOD_CK1_1 202 208 PF00069 0.426
MOD_CK1_1 228 234 PF00069 0.505
MOD_CK1_1 268 274 PF00069 0.650
MOD_CK1_1 310 316 PF00069 0.721
MOD_CK1_1 331 337 PF00069 0.566
MOD_CK1_1 392 398 PF00069 0.404
MOD_CK1_1 403 409 PF00069 0.352
MOD_CK1_1 503 509 PF00069 0.365
MOD_CK1_1 627 633 PF00069 0.376
MOD_CK1_1 634 640 PF00069 0.353
MOD_CK1_1 742 748 PF00069 0.313
MOD_CK1_1 857 863 PF00069 0.373
MOD_CK2_1 204 210 PF00069 0.560
MOD_CK2_1 31 37 PF00069 0.632
MOD_CK2_1 327 333 PF00069 0.695
MOD_CK2_1 41 47 PF00069 0.626
MOD_CK2_1 593 599 PF00069 0.401
MOD_CK2_1 731 737 PF00069 0.415
MOD_CK2_1 980 986 PF00069 0.254
MOD_CK2_1 989 995 PF00069 0.254
MOD_Cter_Amidation 347 350 PF01082 0.395
MOD_GlcNHglycan 1053 1056 PF01048 0.699
MOD_GlcNHglycan 108 111 PF01048 0.683
MOD_GlcNHglycan 134 137 PF01048 0.586
MOD_GlcNHglycan 147 150 PF01048 0.604
MOD_GlcNHglycan 199 202 PF01048 0.409
MOD_GlcNHglycan 256 259 PF01048 0.766
MOD_GlcNHglycan 26 29 PF01048 0.642
MOD_GlcNHglycan 265 268 PF01048 0.683
MOD_GlcNHglycan 391 394 PF01048 0.420
MOD_GlcNHglycan 402 405 PF01048 0.386
MOD_GlcNHglycan 528 531 PF01048 0.376
MOD_GlcNHglycan 537 540 PF01048 0.354
MOD_GlcNHglycan 633 636 PF01048 0.297
MOD_GlcNHglycan 67 71 PF01048 0.634
MOD_GlcNHglycan 813 816 PF01048 0.266
MOD_GlcNHglycan 830 833 PF01048 0.207
MOD_GlcNHglycan 962 965 PF01048 0.281
MOD_GSK3_1 1011 1018 PF00069 0.541
MOD_GSK3_1 1027 1034 PF00069 0.590
MOD_GSK3_1 1042 1049 PF00069 0.611
MOD_GSK3_1 1051 1058 PF00069 0.711
MOD_GSK3_1 1063 1070 PF00069 0.654
MOD_GSK3_1 128 135 PF00069 0.570
MOD_GSK3_1 138 145 PF00069 0.548
MOD_GSK3_1 15 22 PF00069 0.669
MOD_GSK3_1 189 196 PF00069 0.478
MOD_GSK3_1 224 231 PF00069 0.579
MOD_GSK3_1 263 270 PF00069 0.649
MOD_GSK3_1 307 314 PF00069 0.730
MOD_GSK3_1 323 330 PF00069 0.723
MOD_GSK3_1 400 407 PF00069 0.410
MOD_GSK3_1 450 457 PF00069 0.377
MOD_GSK3_1 461 468 PF00069 0.394
MOD_GSK3_1 627 634 PF00069 0.266
MOD_GSK3_1 709 716 PF00069 0.553
MOD_GSK3_1 738 745 PF00069 0.320
MOD_GSK3_1 850 857 PF00069 0.298
MOD_GSK3_1 89 96 PF00069 0.626
MOD_LATS_1 54 60 PF00433 0.558
MOD_LATS_1 852 858 PF00433 0.373
MOD_N-GLC_1 857 862 PF02516 0.269
MOD_NEK2_1 1036 1041 PF00069 0.764
MOD_NEK2_1 1077 1082 PF00069 0.680
MOD_NEK2_1 132 137 PF00069 0.445
MOD_NEK2_1 139 144 PF00069 0.428
MOD_NEK2_1 169 174 PF00069 0.435
MOD_NEK2_1 197 202 PF00069 0.417
MOD_NEK2_1 225 230 PF00069 0.556
MOD_NEK2_1 450 455 PF00069 0.399
MOD_NEK2_1 460 465 PF00069 0.455
MOD_NEK2_1 479 484 PF00069 0.479
MOD_NEK2_1 525 530 PF00069 0.299
MOD_NEK2_1 624 629 PF00069 0.382
MOD_NEK2_1 677 682 PF00069 0.253
MOD_NEK2_1 749 754 PF00069 0.313
MOD_NEK2_1 811 816 PF00069 0.265
MOD_NEK2_1 980 985 PF00069 0.284
MOD_NEK2_1 999 1004 PF00069 0.120
MOD_PIKK_1 202 208 PF00454 0.416
MOD_PIKK_1 230 236 PF00454 0.538
MOD_PIKK_1 323 329 PF00454 0.572
MOD_PIKK_1 404 410 PF00454 0.372
MOD_PIKK_1 41 47 PF00454 0.719
MOD_PIKK_1 425 431 PF00454 0.358
MOD_PIKK_1 695 701 PF00454 0.318
MOD_PIKK_1 867 873 PF00454 0.444
MOD_PKA_1 440 446 PF00069 0.367
MOD_PKA_1 535 541 PF00069 0.477
MOD_PKA_1 942 948 PF00069 0.355
MOD_PKA_2 1039 1045 PF00069 0.647
MOD_PKA_2 145 151 PF00069 0.600
MOD_PKA_2 179 185 PF00069 0.492
MOD_PKA_2 372 378 PF00069 0.545
MOD_PKA_2 440 446 PF00069 0.367
MOD_PKA_2 479 485 PF00069 0.450
MOD_PKA_2 55 61 PF00069 0.692
MOD_PKA_2 683 689 PF00069 0.396
MOD_PKA_2 710 716 PF00069 0.407
MOD_PKA_2 739 745 PF00069 0.380
MOD_PKA_2 772 778 PF00069 0.346
MOD_PKA_2 937 943 PF00069 0.258
MOD_PKB_1 305 313 PF00069 0.493
MOD_Plk_1 139 145 PF00069 0.619
MOD_Plk_1 500 506 PF00069 0.336
MOD_Plk_1 660 666 PF00069 0.281
MOD_Plk_4 128 134 PF00069 0.533
MOD_Plk_4 139 145 PF00069 0.504
MOD_Plk_4 392 398 PF00069 0.342
MOD_Plk_4 489 495 PF00069 0.319
MOD_Plk_4 619 625 PF00069 0.272
MOD_Plk_4 742 748 PF00069 0.302
MOD_Plk_4 772 778 PF00069 0.382
MOD_Plk_4 861 867 PF00069 0.269
MOD_ProDKin_1 1029 1035 PF00069 0.750
MOD_ProDKin_1 1046 1052 PF00069 0.657
MOD_ProDKin_1 15 21 PF00069 0.727
MOD_ProDKin_1 558 564 PF00069 0.433
MOD_ProDKin_1 613 619 PF00069 0.396
MOD_ProDKin_1 643 649 PF00069 0.340
MOD_ProDKin_1 801 807 PF00069 0.402
MOD_ProDKin_1 886 892 PF00069 0.413
MOD_SUMO_rev_2 1059 1069 PF00179 0.545
MOD_SUMO_rev_2 205 214 PF00179 0.502
MOD_SUMO_rev_2 279 289 PF00179 0.552
MOD_SUMO_rev_2 831 837 PF00179 0.260
TRG_DiLeu_BaEn_1 210 215 PF01217 0.524
TRG_DiLeu_BaEn_1 285 290 PF01217 0.403
TRG_DiLeu_BaEn_1 995 1000 PF01217 0.288
TRG_DiLeu_LyEn_5 946 951 PF01217 0.347
TRG_ENDOCYTIC_2 241 244 PF00928 0.530
TRG_ENDOCYTIC_2 491 494 PF00928 0.302
TRG_ENDOCYTIC_2 947 950 PF00928 0.300
TRG_ENDOCYTIC_2 977 980 PF00928 0.254
TRG_ENDOCYTIC_2 987 990 PF00928 0.254
TRG_ER_diArg_1 1082 1084 PF00400 0.584
TRG_ER_diArg_1 335 338 PF00400 0.512
TRG_ER_diArg_1 369 371 PF00400 0.486
TRG_ER_diArg_1 430 432 PF00400 0.398
TRG_ER_diArg_1 440 442 PF00400 0.396
TRG_ER_diArg_1 517 520 PF00400 0.366
TRG_ER_diArg_1 608 611 PF00400 0.263
TRG_ER_diArg_1 942 944 PF00400 0.384
TRG_NLS_Bipartite_1 1071 1085 PF00514 0.687
TRG_Pf-PMV_PEXEL_1 1004 1008 PF00026 0.534
TRG_Pf-PMV_PEXEL_1 173 177 PF00026 0.415
TRG_Pf-PMV_PEXEL_1 291 296 PF00026 0.559
TRG_Pf-PMV_PEXEL_1 387 391 PF00026 0.317
TRG_Pf-PMV_PEXEL_1 41 45 PF00026 0.519
TRG_Pf-PMV_PEXEL_1 610 614 PF00026 0.269
TRG_Pf-PMV_PEXEL_1 809 813 PF00026 0.313
TRG_Pf-PMV_PEXEL_1 835 839 PF00026 0.254
TRG_PTS1 1083 1086 PF00515 0.694

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IKA7 Leptomonas seymouri 76% 100%
A0A0N1PEU4 Leptomonas seymouri 35% 100%
A0A0S4ITR4 Bodo saltans 48% 100%
A0A1X0NVG5 Trypanosomatidae 55% 100%
A0A1X0P872 Trypanosomatidae 35% 100%
A0A3Q8II71 Leishmania donovani 35% 100%
A0A3Q8IJ24 Leishmania donovani 35% 100%
A0A3S7WYA1 Leishmania donovani 100% 100%
A0A422N8L3 Trypanosoma rangeli 56% 100%
A4HAT8 Leishmania braziliensis 36% 100%
A4HDG6 Leishmania braziliensis 82% 100%
A4HNU7 Leishmania braziliensis 34% 100%
A4IA06 Leishmania infantum 35% 100%
A4ICP7 Leishmania infantum 34% 100%
D0A778 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 52% 100%
E9ASK7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 39% 100%
E9AWV1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 93% 100%
E9B512 Leishmania mexicana (strain MHOM/GT/2001/U1103) 36% 100%
P20095 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 37% 100%
P45018 Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) 33% 83%
Q4Q1Y9 Leishmania major 34% 100%
Q4Q2X4 Leishmania major 35% 100%
Q4QAM3 Leishmania major 95% 100%
Q54MH3 Dictyostelium discoideum 39% 98%
Q9HDY4 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 30% 92%
V5BV22 Trypanosoma cruzi 36% 100%
V5C0I9 Trypanosoma cruzi 64% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS