Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

F-box domain/F-box-like/Kelch motif/Galactose oxidase - central domain containing protein - putative

Species:

Leishmania infantum

UniProt:

A4I0T9_LEIIN

TriTrypDb:

LINF_240015400

Length:

981

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I0T9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I0T9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	350	354	PF00656	0.660
CLV_C14_Caspase3-7	368	372	PF00656	0.515
CLV_C14_Caspase3-7	587	591	PF00656	0.686
CLV_NRD_NRD_1	248	250	PF00675	0.405
CLV_NRD_NRD_1	344	346	PF00675	0.618
CLV_NRD_NRD_1	377	379	PF00675	0.644
CLV_NRD_NRD_1	577	579	PF00675	0.670
CLV_NRD_NRD_1	606	608	PF00675	0.707
CLV_NRD_NRD_1	609	611	PF00675	0.702
CLV_NRD_NRD_1	627	629	PF00675	0.564
CLV_NRD_NRD_1	637	639	PF00675	0.688
CLV_NRD_NRD_1	689	691	PF00675	0.740
CLV_NRD_NRD_1	722	724	PF00675	0.659
CLV_PCSK_FUR_1	607	611	PF00082	0.720
CLV_PCSK_KEX2_1	112	114	PF00082	0.648
CLV_PCSK_KEX2_1	248	250	PF00082	0.405
CLV_PCSK_KEX2_1	285	287	PF00082	0.405
CLV_PCSK_KEX2_1	336	338	PF00082	0.691
CLV_PCSK_KEX2_1	344	346	PF00082	0.593
CLV_PCSK_KEX2_1	377	379	PF00082	0.644
CLV_PCSK_KEX2_1	579	581	PF00082	0.655
CLV_PCSK_KEX2_1	606	608	PF00082	0.707
CLV_PCSK_KEX2_1	609	611	PF00082	0.702
CLV_PCSK_KEX2_1	627	629	PF00082	0.549
CLV_PCSK_KEX2_1	689	691	PF00082	0.738
CLV_PCSK_KEX2_1	722	724	PF00082	0.659
CLV_PCSK_PC1ET2_1	112	114	PF00082	0.648
CLV_PCSK_PC1ET2_1	285	287	PF00082	0.405
CLV_PCSK_PC1ET2_1	336	338	PF00082	0.691
CLV_PCSK_PC1ET2_1	579	581	PF00082	0.701
CLV_PCSK_PC7_1	718	724	PF00082	0.624
CLV_PCSK_SKI1_1	109	113	PF00082	0.645
CLV_PCSK_SKI1_1	48	52	PF00082	0.405
CLV_PCSK_SKI1_1	667	671	PF00082	0.681
CLV_PCSK_SKI1_1	675	679	PF00082	0.605
CLV_Separin_Metazoa	918	922	PF03568	0.628
DEG_APCC_DBOX_1	47	55	PF00400	0.405
DEG_SPOP_SBC_1	132	136	PF00917	0.701
DEG_SPOP_SBC_1	856	860	PF00917	0.674
DOC_ANK_TNKS_1	835	842	PF00023	0.596
DOC_CKS1_1	454	459	PF01111	0.696
DOC_CKS1_1	697	702	PF01111	0.671
DOC_CYCLIN_RxL_1	787	795	PF00134	0.622
DOC_CYCLIN_yCln2_LP_2	79	85	PF00134	0.356
DOC_CYCLIN_yCln2_LP_2	824	830	PF00134	0.542
DOC_MAPK_FxFP_2	105	108	PF00069	0.614
DOC_MAPK_gen_1	459	468	PF00069	0.652
DOC_MAPK_gen_1	88	97	PF00069	0.586
DOC_PP1_RVXF_1	962	968	PF00149	0.601
DOC_PP2B_LxvP_1	507	510	PF13499	0.535
DOC_PP4_FxxP_1	105	108	PF00568	0.614
DOC_PP4_FxxP_1	533	536	PF00568	0.470
DOC_PP4_FxxP_1	758	761	PF00568	0.648
DOC_USP7_MATH_1	115	119	PF00917	0.773
DOC_USP7_MATH_1	120	124	PF00917	0.735
DOC_USP7_MATH_1	131	135	PF00917	0.576
DOC_USP7_MATH_1	146	150	PF00917	0.603
DOC_USP7_MATH_1	160	164	PF00917	0.667
DOC_USP7_MATH_1	185	189	PF00917	0.678
DOC_USP7_MATH_1	19	23	PF00917	0.388
DOC_USP7_MATH_1	2	6	PF00917	0.603
DOC_USP7_MATH_1	287	291	PF00917	0.405
DOC_USP7_MATH_1	449	453	PF00917	0.662
DOC_USP7_MATH_1	651	655	PF00917	0.733
DOC_USP7_MATH_1	732	736	PF00917	0.651
DOC_USP7_MATH_1	777	781	PF00917	0.650
DOC_USP7_MATH_1	786	790	PF00917	0.573
DOC_USP7_MATH_1	799	803	PF00917	0.490
DOC_USP7_MATH_1	877	881	PF00917	0.644
DOC_USP7_UBL2_3	575	579	PF12436	0.693
DOC_WW_Pin1_4	121	126	PF00397	0.687
DOC_WW_Pin1_4	224	229	PF00397	0.677
DOC_WW_Pin1_4	24	29	PF00397	0.531
DOC_WW_Pin1_4	453	458	PF00397	0.693
DOC_WW_Pin1_4	494	499	PF00397	0.537
DOC_WW_Pin1_4	524	529	PF00397	0.592
DOC_WW_Pin1_4	559	564	PF00397	0.696
DOC_WW_Pin1_4	591	596	PF00397	0.638
DOC_WW_Pin1_4	696	701	PF00397	0.741
DOC_WW_Pin1_4	823	828	PF00397	0.671
DOC_WW_Pin1_4	850	855	PF00397	0.707
DOC_WW_Pin1_4	857	862	PF00397	0.682
DOC_WW_Pin1_4	865	870	PF00397	0.594
LIG_14-3-3_CanoR_1	119	125	PF00244	0.648
LIG_14-3-3_CanoR_1	165	173	PF00244	0.701
LIG_14-3-3_CanoR_1	286	294	PF00244	0.405
LIG_14-3-3_CanoR_1	322	331	PF00244	0.579
LIG_14-3-3_CanoR_1	34	43	PF00244	0.552
LIG_14-3-3_CanoR_1	487	496	PF00244	0.582
LIG_14-3-3_CanoR_1	52	58	PF00244	0.220
LIG_14-3-3_CanoR_1	607	615	PF00244	0.720
LIG_14-3-3_CanoR_1	689	696	PF00244	0.725
LIG_14-3-3_CanoR_1	953	958	PF00244	0.609
LIG_14-3-3_CanoR_1	964	968	PF00244	0.509
LIG_Actin_WH2_2	10	27	PF00022	0.531
LIG_Actin_WH2_2	39	54	PF00022	0.405
LIG_Actin_WH2_2	950	966	PF00022	0.593
LIG_Actin_WH2_2	97	114	PF00022	0.583
LIG_APCC_ABBA_1	421	426	PF00400	0.524
LIG_BIR_III_4	620	624	PF00653	0.673
LIG_EVH1_2	330	334	PF00568	0.624
LIG_FHA_1	189	195	PF00498	0.665
LIG_FHA_1	197	203	PF00498	0.611
LIG_FHA_1	311	317	PF00498	0.405
LIG_FHA_1	541	547	PF00498	0.499
LIG_FHA_1	699	705	PF00498	0.666
LIG_FHA_1	749	755	PF00498	0.629
LIG_FHA_1	777	783	PF00498	0.638
LIG_FHA_1	832	838	PF00498	0.670
LIG_FHA_1	882	888	PF00498	0.665
LIG_FHA_1	958	964	PF00498	0.580
LIG_FHA_2	348	354	PF00498	0.654
LIG_FHA_2	54	60	PF00498	0.405
LIG_FHA_2	582	588	PF00498	0.723
LIG_FHA_2	614	620	PF00498	0.664
LIG_FHA_2	689	695	PF00498	0.705
LIG_FHA_2	935	941	PF00498	0.716
LIG_LIR_Apic_2	408	413	PF02991	0.569
LIG_LIR_Apic_2	530	536	PF02991	0.475
LIG_LIR_Apic_2	795	801	PF02991	0.608
LIG_LIR_Gen_1	187	194	PF02991	0.684
LIG_LIR_Gen_1	312	319	PF02991	0.405
LIG_LIR_Gen_1	37	47	PF02991	0.569
LIG_LIR_Gen_1	446	454	PF02991	0.654
LIG_LIR_Gen_1	475	483	PF02991	0.600
LIG_LIR_Gen_1	59	67	PF02991	0.405
LIG_LIR_Gen_1	802	813	PF02991	0.516
LIG_LIR_Nem_3	187	192	PF02991	0.683
LIG_LIR_Nem_3	201	207	PF02991	0.630
LIG_LIR_Nem_3	256	261	PF02991	0.405
LIG_LIR_Nem_3	273	279	PF02991	0.230
LIG_LIR_Nem_3	312	317	PF02991	0.405
LIG_LIR_Nem_3	37	43	PF02991	0.567
LIG_LIR_Nem_3	446	450	PF02991	0.634
LIG_LIR_Nem_3	475	480	PF02991	0.596
LIG_LIR_Nem_3	56	60	PF02991	0.210
LIG_LIR_Nem_3	752	758	PF02991	0.627
LIG_LIR_Nem_3	802	808	PF02991	0.536
LIG_LIR_Nem_3	815	820	PF02991	0.573
LIG_LIR_Nem_3	880	885	PF02991	0.634
LIG_MYND_1	510	514	PF01753	0.548
LIG_NRBOX	31	37	PF00104	0.513
LIG_Pex14_2	477	481	PF04695	0.476
LIG_REV1ctd_RIR_1	332	341	PF16727	0.624
LIG_REV1ctd_RIR_1	83	92	PF16727	0.576
LIG_SH2_CRK	40	44	PF00017	0.577
LIG_SH2_CRK	410	414	PF00017	0.399
LIG_SH2_CRK	447	451	PF00017	0.637
LIG_SH2_CRK	60	64	PF00017	0.199
LIG_SH2_CRK	805	809	PF00017	0.606
LIG_SH2_NCK_1	447	451	PF00017	0.637
LIG_SH2_NCK_1	60	64	PF00017	0.380
LIG_SH2_PTP2	534	537	PF00017	0.531
LIG_SH2_PTP2	769	772	PF00017	0.642
LIG_SH2_SRC	708	711	PF00017	0.560
LIG_SH2_STAP1	246	250	PF00017	0.405
LIG_SH2_STAT5	106	109	PF00017	0.631
LIG_SH2_STAT5	366	369	PF00017	0.587
LIG_SH2_STAT5	518	521	PF00017	0.489
LIG_SH2_STAT5	53	56	PF00017	0.405
LIG_SH2_STAT5	534	537	PF00017	0.367
LIG_SH2_STAT5	708	711	PF00017	0.560
LIG_SH2_STAT5	769	772	PF00017	0.642
LIG_SH2_STAT5	805	808	PF00017	0.604
LIG_SH3_3	125	131	PF00018	0.629
LIG_SH3_3	222	228	PF00018	0.678
LIG_SH3_3	451	457	PF00018	0.594
LIG_SH3_3	490	496	PF00018	0.552
LIG_SH3_3	508	514	PF00018	0.357
LIG_SH3_3	560	566	PF00018	0.608
LIG_SH3_3	767	773	PF00018	0.649
LIG_SH3_3	851	857	PF00018	0.747
LIG_SH3_3	929	935	PF00018	0.706
LIG_SUMO_SIM_anti_2	779	785	PF11976	0.607
LIG_SUMO_SIM_par_1	190	196	PF11976	0.653
LIG_SUMO_SIM_par_1	315	321	PF11976	0.405
LIG_TRAF2_1	616	619	PF00917	0.676
LIG_TRAF2_1	938	941	PF00917	0.727
LIG_TYR_ITIM	445	450	PF00017	0.638
LIG_TYR_ITIM	58	63	PF00017	0.525
LIG_TYR_ITIM	803	808	PF00017	0.592
LIG_WRC_WIRS_1	54	59	PF05994	0.405
MOD_CDC14_SPxK_1	567	570	PF00782	0.590
MOD_CDK_SPK_2	494	499	PF00069	0.537
MOD_CDK_SPxK_1	453	459	PF00069	0.696
MOD_CDK_SPxK_1	564	570	PF00069	0.587
MOD_CDK_SPxxK_3	696	703	PF00069	0.596
MOD_CK1_1	124	130	PF00069	0.739
MOD_CK1_1	134	140	PF00069	0.627
MOD_CK1_1	142	148	PF00069	0.621
MOD_CK1_1	163	169	PF00069	0.677
MOD_CK1_1	188	194	PF00069	0.642
MOD_CK1_1	61	67	PF00069	0.405
MOD_CK1_1	681	687	PF00069	0.761
MOD_CK1_1	826	832	PF00069	0.634
MOD_CK1_1	860	866	PF00069	0.692
MOD_CK1_1	881	887	PF00069	0.650
MOD_CK2_1	2	8	PF00069	0.658
MOD_CK2_1	581	587	PF00069	0.717
MOD_CK2_1	613	619	PF00069	0.692
MOD_CK2_1	623	629	PF00069	0.657
MOD_CK2_1	660	666	PF00069	0.795
MOD_CK2_1	688	694	PF00069	0.701
MOD_CK2_1	709	715	PF00069	0.581
MOD_CK2_1	934	940	PF00069	0.711
MOD_Cter_Amidation	604	607	PF01082	0.662
MOD_Cter_Amidation	687	690	PF01082	0.614
MOD_GlcNHglycan	139	142	PF01048	0.778
MOD_GlcNHglycan	148	151	PF01048	0.699
MOD_GlcNHglycan	166	169	PF01048	0.758
MOD_GlcNHglycan	179	182	PF01048	0.592
MOD_GlcNHglycan	289	292	PF01048	0.405
MOD_GlcNHglycan	382	385	PF01048	0.634
MOD_GlcNHglycan	389	392	PF01048	0.599
MOD_GlcNHglycan	399	402	PF01048	0.581
MOD_GlcNHglycan	403	406	PF01048	0.554
MOD_GlcNHglycan	447	450	PF01048	0.635
MOD_GlcNHglycan	63	66	PF01048	0.405
MOD_GlcNHglycan	682	686	PF01048	0.599
MOD_GlcNHglycan	711	714	PF01048	0.617
MOD_GlcNHglycan	730	733	PF01048	0.611
MOD_GlcNHglycan	734	737	PF01048	0.723
MOD_GlcNHglycan	8	12	PF01048	0.536
MOD_GlcNHglycan	828	831	PF01048	0.638
MOD_GlcNHglycan	921	924	PF01048	0.682
MOD_GSK3_1	120	127	PF00069	0.684
MOD_GSK3_1	131	138	PF00069	0.658
MOD_GSK3_1	142	149	PF00069	0.695
MOD_GSK3_1	160	167	PF00069	0.519
MOD_GSK3_1	184	191	PF00069	0.673
MOD_GSK3_1	3	10	PF00069	0.601
MOD_GSK3_1	365	372	PF00069	0.619
MOD_GSK3_1	376	383	PF00069	0.651
MOD_GSK3_1	397	404	PF00069	0.667
MOD_GSK3_1	445	452	PF00069	0.645
MOD_GSK3_1	59	66	PF00069	0.400
MOD_GSK3_1	591	598	PF00069	0.705
MOD_GSK3_1	699	706	PF00069	0.646
MOD_GSK3_1	728	735	PF00069	0.659
MOD_GSK3_1	788	795	PF00069	0.619
MOD_GSK3_1	822	829	PF00069	0.675
MOD_GSK3_1	856	863	PF00069	0.680
MOD_GSK3_1	877	884	PF00069	0.611
MOD_GSK3_1	953	960	PF00069	0.586
MOD_N-GLC_1	369	374	PF02516	0.628
MOD_N-GLC_1	450	455	PF02516	0.550
MOD_N-GLC_1	718	723	PF02516	0.648
MOD_N-GLC_1	957	962	PF02516	0.587
MOD_NEK2_1	18	23	PF00069	0.395
MOD_NEK2_1	58	63	PF00069	0.405
MOD_NEK2_1	608	613	PF00069	0.675
MOD_NEK2_1	7	12	PF00069	0.564
MOD_NEK2_1	709	714	PF00069	0.618
MOD_NEK2_1	792	797	PF00069	0.589
MOD_NEK2_1	957	962	PF00069	0.620
MOD_NEK2_1	963	968	PF00069	0.549
MOD_PIKK_1	193	199	PF00454	0.659
MOD_PIKK_1	236	242	PF00454	0.534
MOD_PIKK_1	323	329	PF00454	0.405
MOD_PIKK_1	34	40	PF00454	0.540
MOD_PIKK_1	347	353	PF00454	0.590
MOD_PIKK_1	405	411	PF00454	0.613
MOD_PK_1	462	468	PF00069	0.652
MOD_PKA_2	164	170	PF00069	0.804
MOD_PKA_2	376	382	PF00069	0.690
MOD_PKA_2	608	614	PF00069	0.721
MOD_PKA_2	688	694	PF00069	0.756
MOD_PKA_2	963	969	PF00069	0.598
MOD_Plk_1	440	446	PF00069	0.650
MOD_Plk_1	450	456	PF00069	0.579
MOD_Plk_1	58	64	PF00069	0.405
MOD_Plk_1	749	755	PF00069	0.650
MOD_Plk_1	842	848	PF00069	0.630
MOD_Plk_4	185	191	PF00069	0.670
MOD_Plk_4	19	25	PF00069	0.531
MOD_Plk_4	473	479	PF00069	0.620
MOD_Plk_4	53	59	PF00069	0.332
MOD_Plk_4	749	755	PF00069	0.604
MOD_Plk_4	777	783	PF00069	0.602
MOD_Plk_4	958	964	PF00069	0.628
MOD_ProDKin_1	121	127	PF00069	0.691
MOD_ProDKin_1	224	230	PF00069	0.670
MOD_ProDKin_1	24	30	PF00069	0.527
MOD_ProDKin_1	453	459	PF00069	0.696
MOD_ProDKin_1	494	500	PF00069	0.533
MOD_ProDKin_1	524	530	PF00069	0.586
MOD_ProDKin_1	559	565	PF00069	0.695
MOD_ProDKin_1	591	597	PF00069	0.636
MOD_ProDKin_1	696	702	PF00069	0.741
MOD_ProDKin_1	823	829	PF00069	0.672
MOD_ProDKin_1	850	856	PF00069	0.706
MOD_ProDKin_1	857	863	PF00069	0.683
MOD_ProDKin_1	865	871	PF00069	0.594
MOD_SUMO_rev_2	312	321	PF00179	0.272
MOD_SUMO_rev_2	940	945	PF00179	0.690
TRG_DiLeu_BaLyEn_6	31	36	PF01217	0.506
TRG_DiLeu_BaLyEn_6	816	821	PF01217	0.610
TRG_ENDOCYTIC_2	222	225	PF00928	0.682
TRG_ENDOCYTIC_2	258	261	PF00928	0.405
TRG_ENDOCYTIC_2	269	272	PF00928	0.292
TRG_ENDOCYTIC_2	314	317	PF00928	0.363
TRG_ENDOCYTIC_2	40	43	PF00928	0.571
TRG_ENDOCYTIC_2	447	450	PF00928	0.635
TRG_ENDOCYTIC_2	534	537	PF00928	0.531
TRG_ENDOCYTIC_2	60	63	PF00928	0.320
TRG_ENDOCYTIC_2	769	772	PF00928	0.642
TRG_ENDOCYTIC_2	805	808	PF00928	0.604
TRG_ER_diArg_1	248	250	PF00400	0.405
TRG_ER_diArg_1	606	609	PF00400	0.715
TRG_ER_diArg_1	722	724	PF00400	0.658
TRG_Pf-PMV_PEXEL_1	34	38	PF00026	0.536
TRG_Pf-PMV_PEXEL_1	544	548	PF00026	0.539

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WYA7	Leishmania donovani	100%	100%
A4HDF8	Leishmania braziliensis	71%	100%
E9AWU3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%
Q4QAN1	Leishmania major	88%	100%