DNA-directed DNA polymerase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DNA polymerase theta (polymerase domain only) - putative

Species:

Leishmania infantum

UniProt:

A4I0S8_LEIIN

TriTrypDb:

LINF_240014100

Length:

1169

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4I0S8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I0S8

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	7
GO:0006259	DNA metabolic process	4	7
GO:0006260	DNA replication	5	7
GO:0006261	DNA-templated DNA replication	6	7
GO:0006725	cellular aromatic compound metabolic process	3	7
GO:0006807	nitrogen compound metabolic process	2	7
GO:0008152	metabolic process	1	7
GO:0009987	cellular process	1	7
GO:0034641	cellular nitrogen compound metabolic process	3	7
GO:0043170	macromolecule metabolic process	3	7
GO:0044237	cellular metabolic process	2	7
GO:0044238	primary metabolic process	2	7
GO:0044260	obsolete cellular macromolecule metabolic process	3	7
GO:0046483	heterocycle metabolic process	3	7
GO:0071704	organic substance metabolic process	2	7
GO:0090304	nucleic acid metabolic process	4	7
GO:1901360	organic cyclic compound metabolic process	3	7
GO:0000731	DNA synthesis involved in DNA repair	6	1
GO:0006281	DNA repair	5	1
GO:0006301	postreplication repair	6	1
GO:0006302	double-strand break repair	6	1
GO:0006950	response to stress	2	1
GO:0006974	DNA damage response	4	1
GO:0009058	biosynthetic process	2	1
GO:0009059	macromolecule biosynthetic process	4	1
GO:0018130	heterocycle biosynthetic process	4	1
GO:0019438	aromatic compound biosynthetic process	4	1
GO:0019985	translesion synthesis	7	1
GO:0033554	cellular response to stress	3	1
GO:0034654	nucleobase-containing compound biosynthetic process	4	1
GO:0044249	cellular biosynthetic process	3	1
GO:0044271	cellular nitrogen compound biosynthetic process	4	1
GO:0050896	response to stimulus	1	1
GO:0051716	cellular response to stimulus	2	1
GO:0071897	DNA biosynthetic process	5	1
GO:1901362	organic cyclic compound biosynthetic process	4	1
GO:1901576	organic substance biosynthetic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	7
GO:0003677	DNA binding	4	7
GO:0003824	catalytic activity	1	7
GO:0003887	DNA-directed DNA polymerase activity	5	7
GO:0005488	binding	1	7
GO:0016740	transferase activity	2	7
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	7
GO:0016779	nucleotidyltransferase activity	4	7
GO:0034061	DNA polymerase activity	4	7
GO:0097159	organic cyclic compound binding	2	7
GO:0140097	catalytic activity, acting on DNA	3	7
GO:0140640	catalytic activity, acting on a nucleic acid	2	7
GO:1901363	heterocyclic compound binding	2	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	421	425	PF00656	0.781
CLV_C14_Caspase3-7	436	440	PF00656	0.569
CLV_C14_Caspase3-7	454	458	PF00656	0.548
CLV_MEL_PAP_1	1150	1156	PF00089	0.346
CLV_MEL_PAP_1	604	610	PF00089	0.565
CLV_NRD_NRD_1	1021	1023	PF00675	0.419
CLV_NRD_NRD_1	1052	1054	PF00675	0.346
CLV_NRD_NRD_1	1065	1067	PF00675	0.346
CLV_NRD_NRD_1	163	165	PF00675	0.774
CLV_NRD_NRD_1	191	193	PF00675	0.724
CLV_NRD_NRD_1	452	454	PF00675	0.614
CLV_NRD_NRD_1	512	514	PF00675	0.740
CLV_NRD_NRD_1	524	526	PF00675	0.656
CLV_NRD_NRD_1	7	9	PF00675	0.758
CLV_NRD_NRD_1	760	762	PF00675	0.605
CLV_PCSK_FUR_1	520	524	PF00082	0.735
CLV_PCSK_KEX2_1	1021	1023	PF00082	0.419
CLV_PCSK_KEX2_1	1064	1066	PF00082	0.346
CLV_PCSK_KEX2_1	191	193	PF00082	0.725
CLV_PCSK_KEX2_1	452	454	PF00082	0.614
CLV_PCSK_KEX2_1	511	513	PF00082	0.692
CLV_PCSK_KEX2_1	522	524	PF00082	0.727
CLV_PCSK_KEX2_1	7	9	PF00082	0.721
CLV_PCSK_KEX2_1	87	89	PF00082	0.786
CLV_PCSK_PC1ET2_1	511	513	PF00082	0.702
CLV_PCSK_PC1ET2_1	87	89	PF00082	0.786
CLV_PCSK_PC7_1	1017	1023	PF00082	0.391
CLV_PCSK_PC7_1	518	524	PF00082	0.691
CLV_PCSK_SKI1_1	1017	1021	PF00082	0.391
CLV_PCSK_SKI1_1	248	252	PF00082	0.657
CLV_PCSK_SKI1_1	328	332	PF00082	0.563
CLV_PCSK_SKI1_1	338	342	PF00082	0.589
CLV_PCSK_SKI1_1	397	401	PF00082	0.629
CLV_PCSK_SKI1_1	512	516	PF00082	0.719
CLV_PCSK_SKI1_1	551	555	PF00082	0.588
CLV_Separin_Metazoa	1126	1130	PF03568	0.619
CLV_Separin_Metazoa	705	709	PF03568	0.681
DEG_APCC_DBOX_1	247	255	PF00400	0.650
DEG_APCC_DBOX_1	347	355	PF00400	0.698
DEG_APCC_DBOX_1	367	375	PF00400	0.376
DEG_APCC_DBOX_1	752	760	PF00400	0.595
DEG_SCF_FBW7_2	170	176	PF00400	0.791
DEG_SPOP_SBC_1	70	74	PF00917	0.777
DOC_CDC14_PxL_1	311	319	PF14671	0.615
DOC_CKS1_1	170	175	PF01111	0.789
DOC_CYCLIN_RxL_1	322	333	PF00134	0.563
DOC_CYCLIN_RxL_1	334	346	PF00134	0.587
DOC_CYCLIN_RxL_1	506	517	PF00134	0.776
DOC_CYCLIN_yCln2_LP_2	1144	1150	PF00134	0.546
DOC_CYCLIN_yCln2_LP_2	15	18	PF00134	0.748
DOC_MAPK_gen_1	1140	1150	PF00069	0.546
DOC_MAPK_gen_1	39	48	PF00069	0.713
DOC_MAPK_gen_1	761	769	PF00069	0.634
DOC_MAPK_gen_1	87	94	PF00069	0.766
DOC_MAPK_MEF2A_6	1140	1148	PF00069	0.546
DOC_MAPK_MEF2A_6	209	217	PF00069	0.704
DOC_MAPK_MEF2A_6	368	375	PF00069	0.708
DOC_MAPK_MEF2A_6	762	771	PF00069	0.721
DOC_MAPK_MEF2A_6	87	94	PF00069	0.766
DOC_MAPK_MEF2A_6	964	971	PF00069	0.546
DOC_PP1_RVXF_1	336	342	PF00149	0.584
DOC_PP2B_LxvP_1	1144	1147	PF13499	0.546
DOC_PP2B_LxvP_1	15	18	PF13499	0.709
DOC_PP2B_LxvP_1	321	324	PF13499	0.624
DOC_PP2B_LxvP_1	951	954	PF13499	0.546
DOC_PP4_FxxP_1	375	378	PF00568	0.727
DOC_USP7_MATH_1	1006	1010	PF00917	0.577
DOC_USP7_MATH_1	1041	1045	PF00917	0.619
DOC_USP7_MATH_1	122	126	PF00917	0.779
DOC_USP7_MATH_1	127	131	PF00917	0.700
DOC_USP7_MATH_1	250	254	PF00917	0.649
DOC_USP7_MATH_1	418	422	PF00917	0.719
DOC_USP7_MATH_1	576	580	PF00917	0.696
DOC_USP7_MATH_1	671	675	PF00917	0.675
DOC_USP7_MATH_1	68	72	PF00917	0.782
DOC_USP7_MATH_1	722	726	PF00917	0.615
DOC_USP7_MATH_1	775	779	PF00917	0.603
DOC_USP7_MATH_1	784	788	PF00917	0.674
DOC_USP7_MATH_1	792	796	PF00917	0.713
DOC_USP7_MATH_1	841	845	PF00917	0.540
DOC_USP7_MATH_2	30	36	PF00917	0.579
DOC_USP7_UBL2_3	762	766	PF12436	0.629
DOC_WW_Pin1_4	118	123	PF00397	0.742
DOC_WW_Pin1_4	131	136	PF00397	0.558
DOC_WW_Pin1_4	169	174	PF00397	0.783
DOC_WW_Pin1_4	24	29	PF00397	0.730
DOC_WW_Pin1_4	596	601	PF00397	0.656
DOC_WW_Pin1_4	606	611	PF00397	0.607
DOC_WW_Pin1_4	700	705	PF00397	0.647
DOC_WW_Pin1_4	78	83	PF00397	0.782
DOC_WW_Pin1_4	839	844	PF00397	0.573
LIG_14-3-3_CanoR_1	1053	1057	PF00244	0.546
LIG_14-3-3_CanoR_1	1093	1097	PF00244	0.619
LIG_14-3-3_CanoR_1	164	171	PF00244	0.768
LIG_14-3-3_CanoR_1	224	232	PF00244	0.609
LIG_14-3-3_CanoR_1	241	247	PF00244	0.664
LIG_14-3-3_CanoR_1	551	556	PF00244	0.481
LIG_14-3-3_CanoR_1	696	704	PF00244	0.554
LIG_14-3-3_CanoR_1	749	756	PF00244	0.584
LIG_14-3-3_CanoR_1	796	802	PF00244	0.409
LIG_14-3-3_CanoR_1	8	18	PF00244	0.618
LIG_14-3-3_CanoR_1	814	822	PF00244	0.494
LIG_14-3-3_CanoR_1	831	835	PF00244	0.419
LIG_14-3-3_CanoR_1	869	874	PF00244	0.607
LIG_Actin_WH2_2	1019	1037	PF00022	0.530
LIG_Actin_WH2_2	1127	1145	PF00022	0.619
LIG_Actin_WH2_2	643	661	PF00022	0.475
LIG_APCC_ABBA_1	1109	1114	PF00400	0.546
LIG_APCC_ABBA_1	887	892	PF00400	0.619
LIG_APCC_ABBAyCdc20_2	397	403	PF00400	0.581
LIG_BIR_III_2	168	172	PF00653	0.767
LIG_BIR_III_2	197	201	PF00653	0.675
LIG_BRCT_BRCA1_1	883	887	PF00533	0.549
LIG_BRCT_BRCA1_1	911	915	PF00533	0.546
LIG_Clathr_ClatBox_1	47	51	PF01394	0.704
LIG_eIF4E_1	311	317	PF01652	0.623
LIG_eIF4E_1	337	343	PF01652	0.584
LIG_FHA_1	10	16	PF00498	0.622
LIG_FHA_1	119	125	PF00498	0.727
LIG_FHA_1	135	141	PF00498	0.570
LIG_FHA_1	242	248	PF00498	0.552
LIG_FHA_1	325	331	PF00498	0.555
LIG_FHA_1	344	350	PF00498	0.690
LIG_FHA_1	387	393	PF00498	0.536
LIG_FHA_1	414	420	PF00498	0.788
LIG_FHA_1	550	556	PF00498	0.585
LIG_FHA_1	789	795	PF00498	0.700
LIG_FHA_1	810	816	PF00498	0.524
LIG_FHA_1	831	837	PF00498	0.480
LIG_FHA_1	945	951	PF00498	0.546
LIG_FHA_2	1035	1041	PF00498	0.619
LIG_FHA_2	113	119	PF00498	0.640
LIG_FHA_2	38	44	PF00498	0.740
LIG_FHA_2	464	470	PF00498	0.608
LIG_FHA_2	61	67	PF00498	0.754
LIG_FHA_2	616	622	PF00498	0.599
LIG_FHA_2	642	648	PF00498	0.582
LIG_FHA_2	673	679	PF00498	0.499
LIG_FHA_2	700	706	PF00498	0.718
LIG_FHA_2	84	90	PF00498	0.761
LIG_FHA_2	861	867	PF00498	0.585
LIG_GBD_Chelix_1	1107	1115	PF00786	0.339
LIG_GBD_Chelix_1	970	978	PF00786	0.346
LIG_LIR_Apic_2	1114	1120	PF02991	0.546
LIG_LIR_Gen_1	359	367	PF02991	0.492
LIG_LIR_Gen_1	554	565	PF02991	0.635
LIG_LIR_Gen_1	618	627	PF02991	0.593
LIG_LIR_Gen_1	868	878	PF02991	0.498
LIG_LIR_Gen_1	912	923	PF02991	0.506
LIG_LIR_Nem_3	1095	1099	PF02991	0.619
LIG_LIR_Nem_3	309	314	PF02991	0.556
LIG_LIR_Nem_3	359	363	PF02991	0.572
LIG_LIR_Nem_3	545	550	PF02991	0.616
LIG_LIR_Nem_3	554	560	PF02991	0.591
LIG_LIR_Nem_3	618	622	PF02991	0.580
LIG_LIR_Nem_3	688	694	PF02991	0.420
LIG_LIR_Nem_3	758	763	PF02991	0.573
LIG_LIR_Nem_3	868	873	PF02991	0.500
LIG_LIR_Nem_3	884	890	PF02991	0.521
LIG_LIR_Nem_3	912	918	PF02991	0.506
LIG_LYPXL_S_1	1026	1030	PF13949	0.330
LIG_LYPXL_yS_3	1027	1030	PF13949	0.546
LIG_LYPXL_yS_3	311	314	PF13949	0.633
LIG_NRBOX	316	322	PF00104	0.580
LIG_NRBOX	335	341	PF00104	0.574
LIG_NRBOX	560	566	PF00104	0.701
LIG_PCNA_PIPBox_1	895	904	PF02747	0.619
LIG_PCNA_yPIPBox_3	939	952	PF02747	0.619
LIG_SH2_CRK	1117	1121	PF00017	0.546
LIG_SH2_CRK	337	341	PF00017	0.587
LIG_SH2_CRK	547	551	PF00017	0.701
LIG_SH2_CRK	629	633	PF00017	0.536
LIG_SH2_CRK	691	695	PF00017	0.364
LIG_SH2_CRK	902	906	PF00017	0.546
LIG_SH2_CRK	972	976	PF00017	0.546
LIG_SH2_PTP2	557	560	PF00017	0.478
LIG_SH2_PTP2	858	861	PF00017	0.494
LIG_SH2_SRC	1099	1102	PF00017	0.546
LIG_SH2_SRC	557	560	PF00017	0.614
LIG_SH2_SRC	858	861	PF00017	0.549
LIG_SH2_STAP1	619	623	PF00017	0.582
LIG_SH2_STAT3	239	242	PF00017	0.669
LIG_SH2_STAT5	1033	1036	PF00017	0.546
LIG_SH2_STAT5	1099	1102	PF00017	0.546
LIG_SH2_STAT5	303	306	PF00017	0.671
LIG_SH2_STAT5	557	560	PF00017	0.501
LIG_SH2_STAT5	714	717	PF00017	0.587
LIG_SH2_STAT5	746	749	PF00017	0.571
LIG_SH2_STAT5	858	861	PF00017	0.526
LIG_SH2_STAT5	902	905	PF00017	0.558
LIG_SH3_2	826	831	PF14604	0.619
LIG_SH3_3	1095	1101	PF00018	0.546
LIG_SH3_3	1143	1149	PF00018	0.619
LIG_SH3_3	144	150	PF00018	0.777
LIG_SH3_3	167	173	PF00018	0.786
LIG_SH3_3	23	29	PF00018	0.730
LIG_SH3_3	309	315	PF00018	0.638
LIG_SH3_3	352	358	PF00018	0.685
LIG_SH3_3	564	570	PF00018	0.707
LIG_SH3_3	572	578	PF00018	0.672
LIG_SH3_3	667	673	PF00018	0.671
LIG_SH3_3	701	707	PF00018	0.631
LIG_SH3_3	823	829	PF00018	0.619
LIG_SH3_3	856	862	PF00018	0.551
LIG_SH3_3	885	891	PF00018	0.602
LIG_SUMO_SIM_anti_2	370	375	PF11976	0.704
LIG_SUMO_SIM_anti_2	941	947	PF11976	0.556
LIG_SUMO_SIM_par_1	211	216	PF11976	0.683
LIG_SUMO_SIM_par_1	352	359	PF11976	0.586
LIG_SUMO_SIM_par_1	562	569	PF11976	0.605
LIG_SUMO_SIM_par_1	941	947	PF11976	0.546
LIG_TRAF2_1	1037	1040	PF00917	0.619
LIG_TRAF2_1	1123	1126	PF00917	0.494
LIG_TRAF2_1	115	118	PF00917	0.572
LIG_TRAF2_1	40	43	PF00917	0.732
LIG_TRAF2_1	429	432	PF00917	0.726
LIG_TRAF2_1	862	865	PF00917	0.619
LIG_TRAF2_1	931	934	PF00917	0.619
LIG_TRAF2_1	99	102	PF00917	0.772
LIG_TRFH_1	887	891	PF08558	0.513
LIG_TYR_ITIM	335	340	PF00017	0.568
LIG_TYR_ITIM	555	560	PF00017	0.612
LIG_TYR_ITIM	970	975	PF00017	0.411
LIG_WRC_WIRS_1	1042	1047	PF05994	0.436
LIG_WRC_WIRS_1	910	915	PF05994	0.411
LIG_WW_3	828	832	PF00397	0.513
MOD_CDK_SPxK_1	839	845	PF00069	0.436
MOD_CK1_1	163	169	PF00069	0.788
MOD_CK1_1	185	191	PF00069	0.743
MOD_CK1_1	274	280	PF00069	0.738
MOD_CK1_1	297	303	PF00069	0.656
MOD_CK1_1	386	392	PF00069	0.676
MOD_CK1_1	528	534	PF00069	0.751
MOD_CK1_1	586	592	PF00069	0.658
MOD_CK1_1	59	65	PF00069	0.799
MOD_CK1_1	599	605	PF00069	0.663
MOD_CK1_1	69	75	PF00069	0.691
MOD_CK1_1	787	793	PF00069	0.639
MOD_CK1_1	844	850	PF00069	0.450
MOD_CK2_1	1034	1040	PF00069	0.513
MOD_CK2_1	112	118	PF00069	0.772
MOD_CK2_1	127	133	PF00069	0.549
MOD_CK2_1	37	43	PF00069	0.754
MOD_CK2_1	420	426	PF00069	0.739
MOD_CK2_1	606	612	PF00069	0.624
MOD_CK2_1	672	678	PF00069	0.496
MOD_CK2_1	699	705	PF00069	0.719
MOD_CK2_1	775	781	PF00069	0.718
MOD_CK2_1	83	89	PF00069	0.766
MOD_CK2_1	869	875	PF00069	0.489
MOD_Cter_Amidation	1051	1054	PF01082	0.411
MOD_Cter_Amidation	450	453	PF01082	0.534
MOD_GlcNHglycan	1008	1011	PF01048	0.523
MOD_GlcNHglycan	1050	1053	PF01048	0.411
MOD_GlcNHglycan	1083	1086	PF01048	0.513
MOD_GlcNHglycan	1150	1153	PF01048	0.319
MOD_GlcNHglycan	123	127	PF01048	0.782
MOD_GlcNHglycan	129	132	PF01048	0.682
MOD_GlcNHglycan	159	163	PF01048	0.747
MOD_GlcNHglycan	275	279	PF01048	0.759
MOD_GlcNHglycan	4	7	PF01048	0.754
MOD_GlcNHglycan	43	46	PF01048	0.705
MOD_GlcNHglycan	496	499	PF01048	0.719
MOD_GlcNHglycan	502	505	PF01048	0.678
MOD_GlcNHglycan	527	530	PF01048	0.731
MOD_GlcNHglycan	578	581	PF01048	0.647
MOD_GlcNHglycan	601	604	PF01048	0.763
MOD_GlcNHglycan	68	71	PF01048	0.769
MOD_GlcNHglycan	777	780	PF01048	0.628
MOD_GlcNHglycan	816	819	PF01048	0.446
MOD_GlcNHglycan	839	842	PF01048	0.472
MOD_GlcNHglycan	846	849	PF01048	0.375
MOD_GlcNHglycan	883	886	PF01048	0.356
MOD_GlcNHglycan	9	12	PF01048	0.695
MOD_GlcNHglycan	926	929	PF01048	0.411
MOD_GlcNHglycan	936	939	PF01048	0.411
MOD_GSK3_1	1048	1055	PF00069	0.411
MOD_GSK3_1	112	119	PF00069	0.789
MOD_GSK3_1	127	134	PF00069	0.550
MOD_GSK3_1	297	304	PF00069	0.684
MOD_GSK3_1	37	44	PF00069	0.769
MOD_GSK3_1	418	425	PF00069	0.747
MOD_GSK3_1	431	438	PF00069	0.709
MOD_GSK3_1	490	497	PF00069	0.675
MOD_GSK3_1	528	535	PF00069	0.725
MOD_GSK3_1	56	63	PF00069	0.522
MOD_GSK3_1	583	590	PF00069	0.725
MOD_GSK3_1	66	73	PF00069	0.768
MOD_GSK3_1	695	702	PF00069	0.553
MOD_GSK3_1	784	791	PF00069	0.714
MOD_GSK3_1	837	844	PF00069	0.372
MOD_N-GLC_1	271	276	PF02516	0.829
MOD_N-GLC_1	297	302	PF02516	0.570
MOD_N-GLC_1	494	499	PF02516	0.767
MOD_N-GLC_1	634	639	PF02516	0.504
MOD_N-GLC_1	808	813	PF02516	0.362
MOD_NEK2_1	1034	1039	PF00069	0.513
MOD_NEK2_1	1107	1112	PF00069	0.513
MOD_NEK2_1	139	144	PF00069	0.770
MOD_NEK2_1	201	206	PF00069	0.744
MOD_NEK2_1	296	301	PF00069	0.615
MOD_NEK2_1	330	335	PF00069	0.564
MOD_NEK2_1	413	418	PF00069	0.758
MOD_NEK2_1	514	519	PF00069	0.805
MOD_NEK2_1	532	537	PF00069	0.593
MOD_NEK2_1	587	592	PF00069	0.747
MOD_NEK2_2	849	854	PF00069	0.474
MOD_NEK2_2	894	899	PF00069	0.411
MOD_PIKK_1	112	118	PF00454	0.792
MOD_PIKK_1	223	229	PF00454	0.582
MOD_PIKK_1	401	407	PF00454	0.689
MOD_PK_1	683	689	PF00069	0.393
MOD_PK_1	88	94	PF00069	0.766
MOD_PK_1	952	958	PF00069	0.513
MOD_PKA_1	7	13	PF00069	0.760
MOD_PKA_2	1034	1040	PF00069	0.515
MOD_PKA_2	1052	1058	PF00069	0.238
MOD_PKA_2	1092	1098	PF00069	0.411
MOD_PKA_2	163	169	PF00069	0.774
MOD_PKA_2	223	229	PF00069	0.697
MOD_PKA_2	240	246	PF00069	0.587
MOD_PKA_2	367	373	PF00069	0.603
MOD_PKA_2	59	65	PF00069	0.764
MOD_PKA_2	66	72	PF00069	0.688
MOD_PKA_2	695	701	PF00069	0.539
MOD_PKA_2	7	13	PF00069	0.760
MOD_PKA_2	748	754	PF00069	0.569
MOD_PKA_2	775	781	PF00069	0.580
MOD_PKA_2	830	836	PF00069	0.361
MOD_PKA_2	844	850	PF00069	0.472
MOD_PKB_1	39	47	PF00069	0.702
MOD_PKB_1	523	531	PF00069	0.721
MOD_Plk_1	297	303	PF00069	0.570
MOD_Plk_1	349	355	PF00069	0.608
MOD_Plk_1	386	392	PF00069	0.518
MOD_Plk_1	634	640	PF00069	0.508
MOD_Plk_1	849	855	PF00069	0.513
MOD_Plk_2-3	350	356	PF00069	0.609
MOD_Plk_2-3	422	428	PF00069	0.755
MOD_Plk_2-3	860	866	PF00069	0.513
MOD_Plk_4	1052	1058	PF00069	0.471
MOD_Plk_4	1092	1098	PF00069	0.411
MOD_Plk_4	134	140	PF00069	0.748
MOD_Plk_4	201	207	PF00069	0.741
MOD_Plk_4	297	303	PF00069	0.609
MOD_Plk_4	350	356	PF00069	0.684
MOD_Plk_4	946	952	PF00069	0.411
MOD_ProDKin_1	118	124	PF00069	0.741
MOD_ProDKin_1	131	137	PF00069	0.557
MOD_ProDKin_1	169	175	PF00069	0.785
MOD_ProDKin_1	24	30	PF00069	0.731
MOD_ProDKin_1	596	602	PF00069	0.656
MOD_ProDKin_1	606	612	PF00069	0.605
MOD_ProDKin_1	700	706	PF00069	0.640
MOD_ProDKin_1	78	84	PF00069	0.781
MOD_ProDKin_1	839	845	PF00069	0.450
TRG_DiLeu_BaEn_1	395	400	PF01217	0.639
TRG_DiLeu_BaLyEn_6	312	317	PF01217	0.618
TRG_DiLeu_BaLyEn_6	331	336	PF01217	0.564
TRG_DiLeu_BaLyEn_6	510	515	PF01217	0.717
TRG_DiLeu_BaLyEn_6	560	565	PF01217	0.697
TRG_DiLeu_BaLyEn_6	713	718	PF01217	0.492
TRG_DiLeu_BaLyEn_6	918	923	PF01217	0.513
TRG_ENDOCYTIC_2	1027	1030	PF00928	0.411
TRG_ENDOCYTIC_2	311	314	PF00928	0.633
TRG_ENDOCYTIC_2	337	340	PF00928	0.581
TRG_ENDOCYTIC_2	547	550	PF00928	0.608
TRG_ENDOCYTIC_2	557	560	PF00928	0.590
TRG_ENDOCYTIC_2	619	622	PF00928	0.586
TRG_ENDOCYTIC_2	629	632	PF00928	0.545
TRG_ENDOCYTIC_2	691	694	PF00928	0.359
TRG_ENDOCYTIC_2	714	717	PF00928	0.587
TRG_ENDOCYTIC_2	856	859	PF00928	0.411
TRG_ENDOCYTIC_2	972	975	PF00928	0.411
TRG_ER_diArg_1	1020	1022	PF00400	0.513
TRG_ER_diArg_1	1064	1066	PF00400	0.338
TRG_ER_diArg_1	190	192	PF00400	0.747
TRG_ER_diArg_1	480	483	PF00400	0.726
TRG_ER_diArg_1	512	514	PF00400	0.697
TRG_ER_diArg_1	515	518	PF00400	0.692
TRG_ER_diArg_1	520	523	PF00400	0.704
TRG_ER_diArg_1	524	526	PF00400	0.719
TRG_ER_diArg_1	753	756	PF00400	0.564
TRG_NES_CRM1_1	365	380	PF08389	0.505
TRG_NES_CRM1_1	758	773	PF08389	0.712
TRG_Pf-PMV_PEXEL_1	1068	1072	PF00026	0.513
TRG_Pf-PMV_PEXEL_1	1133	1137	PF00026	0.411
TRG_Pf-PMV_PEXEL_1	397	402	PF00026	0.630
TRG_Pf-PMV_PEXEL_1	482	486	PF00026	0.735
TRG_Pf-PMV_PEXEL_1	716	721	PF00026	0.588

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6B8	Leptomonas seymouri	50%	100%
A0A3Q8ICZ6	Leishmania donovani	98%	100%
A4HDE5	Leishmania braziliensis	76%	99%
E9AWT0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4QAP4	Leishmania major	90%	100%