LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4I0R9_LEIIN
TriTrypDb:
LINF_240013100
Length:
599

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I0R9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I0R9

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 166 170 PF00656 0.629
CLV_C14_Caspase3-7 325 329 PF00656 0.677
CLV_C14_Caspase3-7 38 42 PF00656 0.576
CLV_NRD_NRD_1 104 106 PF00675 0.661
CLV_NRD_NRD_1 186 188 PF00675 0.623
CLV_NRD_NRD_1 217 219 PF00675 0.624
CLV_NRD_NRD_1 23 25 PF00675 0.682
CLV_NRD_NRD_1 26 28 PF00675 0.657
CLV_NRD_NRD_1 315 317 PF00675 0.777
CLV_NRD_NRD_1 323 325 PF00675 0.663
CLV_NRD_NRD_1 412 414 PF00675 0.616
CLV_NRD_NRD_1 56 58 PF00675 0.694
CLV_NRD_NRD_1 80 82 PF00675 0.706
CLV_PCSK_FUR_1 24 28 PF00082 0.686
CLV_PCSK_KEX2_1 104 106 PF00082 0.661
CLV_PCSK_KEX2_1 128 130 PF00082 0.715
CLV_PCSK_KEX2_1 186 188 PF00082 0.623
CLV_PCSK_KEX2_1 217 219 PF00082 0.739
CLV_PCSK_KEX2_1 23 25 PF00082 0.682
CLV_PCSK_KEX2_1 26 28 PF00082 0.657
CLV_PCSK_KEX2_1 314 316 PF00082 0.787
CLV_PCSK_KEX2_1 323 325 PF00082 0.653
CLV_PCSK_KEX2_1 412 414 PF00082 0.610
CLV_PCSK_KEX2_1 56 58 PF00082 0.694
CLV_PCSK_KEX2_1 80 82 PF00082 0.706
CLV_PCSK_PC1ET2_1 128 130 PF00082 0.715
CLV_PCSK_PC7_1 319 325 PF00082 0.669
CLV_PCSK_SKI1_1 412 416 PF00082 0.643
DOC_ANK_TNKS_1 323 330 PF00023 0.679
DOC_ANK_TNKS_1 80 87 PF00023 0.685
DOC_CKS1_1 354 359 PF01111 0.629
DOC_CYCLIN_yClb5_NLxxxL_5 142 148 PF00134 0.608
DOC_MAPK_gen_1 104 111 PF00069 0.588
DOC_MAPK_gen_1 186 193 PF00069 0.625
DOC_MAPK_gen_1 529 536 PF00069 0.609
DOC_MAPK_gen_1 80 89 PF00069 0.605
DOC_MAPK_MEF2A_6 80 89 PF00069 0.605
DOC_MIT_MIM_1 237 247 PF04212 0.420
DOC_PP2B_LxvP_1 545 548 PF13499 0.608
DOC_PP4_FxxP_1 147 150 PF00568 0.636
DOC_USP7_MATH_1 100 104 PF00917 0.641
DOC_USP7_MATH_1 2 6 PF00917 0.673
DOC_USP7_MATH_1 261 265 PF00917 0.564
DOC_USP7_MATH_1 284 288 PF00917 0.623
DOC_USP7_MATH_1 317 321 PF00917 0.638
DOC_USP7_MATH_1 390 394 PF00917 0.625
DOC_USP7_MATH_1 397 401 PF00917 0.585
DOC_USP7_MATH_1 406 410 PF00917 0.524
DOC_USP7_MATH_1 479 483 PF00917 0.621
DOC_USP7_MATH_1 502 506 PF00917 0.736
DOC_USP7_MATH_1 524 528 PF00917 0.711
DOC_USP7_MATH_1 59 63 PF00917 0.647
DOC_WW_Pin1_4 164 169 PF00397 0.468
DOC_WW_Pin1_4 198 203 PF00397 0.637
DOC_WW_Pin1_4 229 234 PF00397 0.585
DOC_WW_Pin1_4 353 358 PF00397 0.672
DOC_WW_Pin1_4 500 505 PF00397 0.705
DOC_WW_Pin1_4 520 525 PF00397 0.719
DOC_WW_Pin1_4 562 567 PF00397 0.742
LIG_14-3-3_CanoR_1 104 112 PF00244 0.649
LIG_14-3-3_CanoR_1 190 194 PF00244 0.672
LIG_14-3-3_CanoR_1 24 30 PF00244 0.683
LIG_14-3-3_CanoR_1 319 323 PF00244 0.715
LIG_14-3-3_CanoR_1 32 39 PF00244 0.605
LIG_14-3-3_CanoR_1 358 364 PF00244 0.711
LIG_14-3-3_CanoR_1 453 461 PF00244 0.541
LIG_14-3-3_CanoR_1 480 486 PF00244 0.645
LIG_14-3-3_CanoR_1 497 504 PF00244 0.758
LIG_14-3-3_CanoR_1 531 537 PF00244 0.692
LIG_Actin_WH2_1 243 261 PF00022 0.470
LIG_BIR_II_1 1 5 PF00653 0.753
LIG_BIR_III_2 446 450 PF00653 0.672
LIG_BIR_III_3 1 5 PF00653 0.648
LIG_BRCT_BRCA1_1 199 203 PF00533 0.611
LIG_BRCT_BRCA1_1 454 458 PF00533 0.798
LIG_BRCT_BRCA1_1 564 568 PF00533 0.634
LIG_BRCT_BRCA1_1 9 13 PF00533 0.576
LIG_deltaCOP1_diTrp_1 340 344 PF00928 0.557
LIG_FHA_1 119 125 PF00498 0.628
LIG_FHA_1 291 297 PF00498 0.609
LIG_FHA_1 350 356 PF00498 0.557
LIG_FHA_1 433 439 PF00498 0.727
LIG_FHA_2 16 22 PF00498 0.634
LIG_FHA_2 26 32 PF00498 0.609
LIG_FHA_2 533 539 PF00498 0.715
LIG_FHA_2 582 588 PF00498 0.666
LIG_LIR_Apic_2 455 460 PF02991 0.668
LIG_LIR_Nem_3 173 177 PF02991 0.698
LIG_LIR_Nem_3 415 421 PF02991 0.661
LIG_LIR_Nem_3 455 461 PF02991 0.792
LIG_PALB2_WD40_1 453 461 PF16756 0.674
LIG_SH2_NCK_1 223 227 PF00017 0.618
LIG_SH2_SRC 209 212 PF00017 0.564
LIG_SH2_SRC 223 226 PF00017 0.570
LIG_SH2_SRC 332 335 PF00017 0.622
LIG_SH2_STAP1 174 178 PF00017 0.574
LIG_SH2_STAP1 209 213 PF00017 0.563
LIG_SH2_STAT3 249 252 PF00017 0.436
LIG_SH2_STAT5 19 22 PF00017 0.622
LIG_SH2_STAT5 249 252 PF00017 0.436
LIG_SH3_3 216 222 PF00018 0.660
LIG_SH3_3 351 357 PF00018 0.620
LIG_SH3_3 446 452 PF00018 0.747
LIG_SH3_3 79 85 PF00018 0.692
LIG_TRAF2_1 47 50 PF00917 0.618
LIG_TRAF2_1 484 487 PF00917 0.536
MOD_CDK_SPK_2 353 358 PF00069 0.626
MOD_CDK_SPxxK_3 229 236 PF00069 0.576
MOD_CDK_SPxxK_3 353 360 PF00069 0.631
MOD_CK1_1 103 109 PF00069 0.649
MOD_CK1_1 201 207 PF00069 0.647
MOD_CK1_1 232 238 PF00069 0.599
MOD_CK1_1 35 41 PF00069 0.614
MOD_CK1_1 372 378 PF00069 0.655
MOD_CK1_1 422 428 PF00069 0.720
MOD_CK1_1 43 49 PF00069 0.600
MOD_CK1_1 500 506 PF00069 0.704
MOD_CK1_1 509 515 PF00069 0.638
MOD_CK1_1 527 533 PF00069 0.684
MOD_CK1_1 561 567 PF00069 0.678
MOD_CK1_1 6 12 PF00069 0.712
MOD_CK2_1 15 21 PF00069 0.630
MOD_CK2_1 25 31 PF00069 0.606
MOD_CK2_1 43 49 PF00069 0.503
MOD_CK2_1 481 487 PF00069 0.547
MOD_CMANNOS 341 344 PF00535 0.553
MOD_Cter_Amidation 21 24 PF01082 0.671
MOD_Cter_Amidation 215 218 PF01082 0.541
MOD_GlcNHglycan 105 108 PF01048 0.624
MOD_GlcNHglycan 156 159 PF01048 0.625
MOD_GlcNHglycan 205 208 PF01048 0.674
MOD_GlcNHglycan 263 266 PF01048 0.516
MOD_GlcNHglycan 302 305 PF01048 0.633
MOD_GlcNHglycan 365 368 PF01048 0.592
MOD_GlcNHglycan 381 385 PF01048 0.578
MOD_GlcNHglycan 399 402 PF01048 0.652
MOD_GlcNHglycan 406 409 PF01048 0.693
MOD_GlcNHglycan 420 424 PF01048 0.529
MOD_GlcNHglycan 454 457 PF01048 0.740
MOD_GlcNHglycan 474 477 PF01048 0.610
MOD_GlcNHglycan 499 502 PF01048 0.692
MOD_GlcNHglycan 504 507 PF01048 0.715
MOD_GlcNHglycan 526 529 PF01048 0.801
MOD_GlcNHglycan 560 563 PF01048 0.700
MOD_GlcNHglycan 571 574 PF01048 0.578
MOD_GlcNHglycan 594 597 PF01048 0.534
MOD_GlcNHglycan 61 64 PF01048 0.556
MOD_GSK3_1 172 179 PF00069 0.699
MOD_GSK3_1 197 204 PF00069 0.657
MOD_GSK3_1 2 9 PF00069 0.652
MOD_GSK3_1 284 291 PF00069 0.578
MOD_GSK3_1 349 356 PF00069 0.742
MOD_GSK3_1 359 366 PF00069 0.729
MOD_GSK3_1 40 47 PF00069 0.554
MOD_GSK3_1 433 440 PF00069 0.758
MOD_GSK3_1 502 509 PF00069 0.790
MOD_GSK3_1 520 527 PF00069 0.721
MOD_GSK3_1 534 541 PF00069 0.655
MOD_GSK3_1 558 565 PF00069 0.631
MOD_LATS_1 410 416 PF00433 0.638
MOD_N-GLC_1 32 37 PF02516 0.691
MOD_N-GLC_1 372 377 PF02516 0.625
MOD_N-GLC_1 44 49 PF02516 0.564
MOD_N-GLC_1 592 597 PF02516 0.566
MOD_NEK2_1 172 177 PF00069 0.694
MOD_NEK2_1 203 208 PF00069 0.604
MOD_NEK2_1 363 368 PF00069 0.666
MOD_NEK2_1 558 563 PF00069 0.719
MOD_NEK2_1 567 572 PF00069 0.737
MOD_NEK2_1 592 597 PF00069 0.530
MOD_NEK2_1 8 13 PF00069 0.533
MOD_NEK2_2 581 586 PF00069 0.633
MOD_PIKK_1 177 183 PF00454 0.651
MOD_PIKK_1 32 38 PF00454 0.688
MOD_PKA_1 412 418 PF00069 0.625
MOD_PKA_2 103 109 PF00069 0.649
MOD_PKA_2 189 195 PF00069 0.670
MOD_PKA_2 235 241 PF00069 0.484
MOD_PKA_2 25 31 PF00069 0.684
MOD_PKA_2 318 324 PF00069 0.765
MOD_PKA_2 359 365 PF00069 0.710
MOD_PKA_2 412 418 PF00069 0.625
MOD_PKA_2 452 458 PF00069 0.545
MOD_PKA_2 479 485 PF00069 0.655
MOD_PKA_2 76 82 PF00069 0.690
MOD_PKB_1 257 265 PF00069 0.545
MOD_Plk_1 253 259 PF00069 0.476
MOD_Plk_1 317 323 PF00069 0.633
MOD_Plk_1 32 38 PF00069 0.645
MOD_Plk_1 44 50 PF00069 0.566
MOD_Plk_1 592 598 PF00069 0.533
MOD_Plk_2-3 15 21 PF00069 0.581
MOD_Plk_4 15 21 PF00069 0.600
MOD_Plk_4 235 241 PF00069 0.493
MOD_ProDKin_1 164 170 PF00069 0.470
MOD_ProDKin_1 198 204 PF00069 0.634
MOD_ProDKin_1 229 235 PF00069 0.578
MOD_ProDKin_1 353 359 PF00069 0.674
MOD_ProDKin_1 500 506 PF00069 0.706
MOD_ProDKin_1 520 526 PF00069 0.716
MOD_ProDKin_1 562 568 PF00069 0.745
TRG_DiLeu_BaEn_1 242 247 PF01217 0.405
TRG_DiLeu_BaEn_1 50 55 PF01217 0.624
TRG_DiLeu_LyEn_5 242 247 PF01217 0.405
TRG_ENDOCYTIC_2 418 421 PF00928 0.716
TRG_ER_diArg_1 217 219 PF00400 0.573
TRG_ER_diArg_1 23 26 PF00400 0.684
TRG_ER_diArg_1 243 246 PF00400 0.590
TRG_ER_diArg_1 255 258 PF00400 0.451
TRG_ER_diArg_1 313 316 PF00400 0.673
TRG_ER_diArg_1 322 324 PF00400 0.597
TRG_ER_diArg_1 357 360 PF00400 0.711
TRG_ER_diArg_1 411 413 PF00400 0.609
TRG_ER_diArg_1 55 57 PF00400 0.685
TRG_ER_diArg_1 80 83 PF00400 0.704

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IG29 Leishmania donovani 99% 100%
A4HDD8 Leishmania braziliensis 59% 99%
E9AWS1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 80% 100%
Q4QAQ3 Leishmania major 84% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS