SUZ domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I0R7_LEIIN

TriTrypDb:

LINF_240012900

Length:

310

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I0R7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I0R7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	285	289	PF00656	0.640
CLV_C14_Caspase3-7	60	64	PF00656	0.591
CLV_NRD_NRD_1	144	146	PF00675	0.612
CLV_NRD_NRD_1	171	173	PF00675	0.594
CLV_NRD_NRD_1	192	194	PF00675	0.535
CLV_NRD_NRD_1	301	303	PF00675	0.545
CLV_NRD_NRD_1	37	39	PF00675	0.671
CLV_PCSK_FUR_1	190	194	PF00082	0.496
CLV_PCSK_KEX2_1	144	146	PF00082	0.612
CLV_PCSK_KEX2_1	171	173	PF00082	0.594
CLV_PCSK_KEX2_1	192	194	PF00082	0.535
CLV_PCSK_KEX2_1	301	303	PF00082	0.545
CLV_PCSK_KEX2_1	36	38	PF00082	0.569
CLV_PCSK_PC1ET2_1	36	38	PF00082	0.569
CLV_PCSK_PC7_1	140	146	PF00082	0.604
CLV_PCSK_SKI1_1	145	149	PF00082	0.679
CLV_PCSK_SKI1_1	199	203	PF00082	0.540
CLV_PCSK_SKI1_1	89	93	PF00082	0.506
DEG_APCC_DBOX_1	198	206	PF00400	0.528
DEG_SCF_TRCP1_1	63	69	PF00400	0.561
DEG_SPOP_SBC_1	130	134	PF00917	0.577
DOC_ANK_TNKS_1	152	159	PF00023	0.678
DOC_CYCLIN_RxL_1	84	94	PF00134	0.540
DOC_MAPK_gen_1	187	197	PF00069	0.497
DOC_MAPK_MEF2A_6	97	104	PF00069	0.561
DOC_PP4_FxxP_1	109	112	PF00568	0.630
DOC_PP4_FxxP_1	231	234	PF00568	0.654
DOC_USP7_MATH_1	126	130	PF00917	0.614
DOC_USP7_MATH_1	13	17	PF00917	0.651
DOC_USP7_MATH_1	131	135	PF00917	0.628
DOC_USP7_MATH_1	178	182	PF00917	0.639
DOC_USP7_MATH_1	40	44	PF00917	0.720
DOC_USP7_MATH_1	53	57	PF00917	0.670
DOC_USP7_MATH_1	66	70	PF00917	0.613
DOC_WW_Pin1_4	271	276	PF00397	0.649
DOC_WW_Pin1_4	304	309	PF00397	0.629
DOC_WW_Pin1_4	96	101	PF00397	0.501
LIG_14-3-3_CanoR_1	251	257	PF00244	0.669
LIG_14-3-3_CanoR_1	301	305	PF00244	0.535
LIG_14-3-3_CanoR_1	38	46	PF00244	0.617
LIG_ActinCP_TwfCPI_2	231	240	PF01115	0.617
LIG_BIR_II_1	1	5	PF00653	0.558
LIG_BIR_III_4	246	250	PF00653	0.629
LIG_BRCT_BRCA1_1	302	306	PF00533	0.650
LIG_FHA_1	97	103	PF00498	0.550
LIG_FHA_2	283	289	PF00498	0.611
LIG_FHA_2	76	82	PF00498	0.520
LIG_Integrin_RGD_1	286	288	PF01839	0.624
LIG_LIR_Apic_2	107	112	PF02991	0.626
LIG_LIR_Apic_2	229	234	PF02991	0.668
LIG_LIR_Gen_1	209	219	PF02991	0.577
LIG_LIR_Nem_3	209	215	PF02991	0.569
LIG_LIR_Nem_3	271	276	PF02991	0.594
LIG_LIR_Nem_3	303	309	PF02991	0.614
LIG_PCNA_yPIPBox_3	82	92	PF02747	0.487
LIG_SH2_CRK	173	177	PF00017	0.629
LIG_SH2_CRK	212	216	PF00017	0.648
LIG_SH2_NCK_1	117	121	PF00017	0.640
LIG_SH2_STAT5	117	120	PF00017	0.681
LIG_SH2_STAT5	235	238	PF00017	0.621
LIG_SH3_1	302	308	PF00018	0.556
LIG_SH3_3	302	308	PF00018	0.624
LIG_TRAF2_1	16	19	PF00917	0.657
LIG_TRAF2_1	181	184	PF00917	0.528
LIG_TYR_ITIM	210	215	PF00017	0.574
MOD_CK1_1	129	135	PF00069	0.623
MOD_CK1_1	252	258	PF00069	0.707
MOD_CK1_1	271	277	PF00069	0.553
MOD_CK1_1	56	62	PF00069	0.678
MOD_CK1_1	64	70	PF00069	0.605
MOD_CK2_1	13	19	PF00069	0.589
MOD_CK2_1	178	184	PF00069	0.530
MOD_CK2_1	75	81	PF00069	0.537
MOD_Cter_Amidation	299	302	PF01082	0.560
MOD_GlcNHglycan	128	131	PF01048	0.653
MOD_GlcNHglycan	134	137	PF01048	0.598
MOD_GlcNHglycan	270	273	PF01048	0.609
MOD_GlcNHglycan	295	298	PF01048	0.644
MOD_GlcNHglycan	302	305	PF01048	0.627
MOD_GlcNHglycan	6	9	PF01048	0.641
MOD_GlcNHglycan	63	66	PF01048	0.622
MOD_GSK3_1	125	132	PF00069	0.633
MOD_GSK3_1	300	307	PF00069	0.686
MOD_GSK3_1	53	60	PF00069	0.707
MOD_N-GLC_1	178	183	PF02516	0.543
MOD_NEK2_1	213	218	PF00069	0.583
MOD_NEK2_1	27	32	PF00069	0.572
MOD_PIKK_1	213	219	PF00454	0.616
MOD_PKA_2	13	19	PF00069	0.589
MOD_PKA_2	227	233	PF00069	0.541
MOD_PKA_2	279	285	PF00069	0.605
MOD_PKA_2	300	306	PF00069	0.537
MOD_PKB_1	266	274	PF00069	0.604
MOD_Plk_1	27	33	PF00069	0.551
MOD_Plk_2-3	206	212	PF00069	0.553
MOD_Plk_4	27	33	PF00069	0.616
MOD_Plk_4	75	81	PF00069	0.521
MOD_ProDKin_1	271	277	PF00069	0.649
MOD_ProDKin_1	304	310	PF00069	0.622
MOD_ProDKin_1	96	102	PF00069	0.501
TRG_DiLeu_BaEn_3	183	189	PF01217	0.448
TRG_ENDOCYTIC_2	212	215	PF00928	0.580
TRG_ER_diArg_1	150	153	PF00400	0.606
TRG_ER_diArg_1	170	172	PF00400	0.728
TRG_ER_diArg_1	189	192	PF00400	0.429
TRG_ER_diArg_1	256	259	PF00400	0.653
TRG_ER_diArg_1	265	268	PF00400	0.570
TRG_NLS_MonoExtC_3	35	40	PF00514	0.503
TRG_NLS_MonoExtN_4	33	40	PF00514	0.497
TRG_Pf-PMV_PEXEL_1	89	94	PF00026	0.509

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5G1	Leptomonas seymouri	41%	100%
A0A3Q8IBA4	Leishmania donovani	98%	100%
A4HDD6	Leishmania braziliensis	68%	99%
E9AWR9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	95%
Q4QAQ5	Leishmania major	85%	99%