Putative mitochondrial translocase subunit

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

mitochondrial translocase subunit - putative

Species:

Leishmania infantum

UniProt:

A4I0R0_LEIIN

TriTrypDb:

LINF_240012200

Length:

Annotations

Annotations by Jardim et al.

Mitochondrial protein, mitochondrial translocase subunit

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I0R0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I0R0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	8	10	PF00675	0.667
CLV_PCSK_KEX2_1	8	10	PF00082	0.667
CLV_PCSK_SKI1_1	10	14	PF00082	0.584
DEG_Nend_UBRbox_3	1	3	PF02207	0.616
LIG_14-3-3_CanoR_1	8	17	PF00244	0.550
LIG_FHA_2	53	59	PF00498	0.454
LIG_LIR_Gen_1	15	23	PF02991	0.414
LIG_Pex14_2	13	17	PF04695	0.497
LIG_Pex14_2	45	49	PF04695	0.452
LIG_PTB_Apo_2	40	47	PF02174	0.475
LIG_PTB_Apo_2	69	76	PF02174	0.399
LIG_PTB_Phospho_1	44	50	PF10480	0.486
LIG_PTB_Phospho_1	69	75	PF10480	0.492
LIG_SH2_STAT5	44	47	PF00017	0.470
LIG_SH3_2	3	8	PF14604	0.550
LIG_TRAF2_1	22	25	PF00917	0.484
LIG_WW_3	5	9	PF00397	0.616
MOD_CK2_1	52	58	PF00069	0.422
MOD_PKA_1	8	14	PF00069	0.570
MOD_PKA_2	8	14	PF00069	0.512
MOD_Plk_1	52	58	PF00069	0.408
MOD_Plk_4	65	71	PF00069	0.479
TRG_ENDOCYTIC_2	75	78	PF00928	0.500
TRG_ER_diArg_1	7	9	PF00400	0.678

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PE09	Leptomonas seymouri	88%	100%
A0A0S4JRX4	Bodo saltans	52%	94%
A0A3Q8ICY5	Leishmania donovani	99%	100%
A4HDC9	Leishmania braziliensis	93%	100%
D0A738	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	51%	100%
E9AWR2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%
Q4QAR1	Leishmania major	99%	100%