Uncharacterized protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I0M6_LEIIN

TriTrypDb:

LINF_240005100

Length:

166

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I0M6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I0M6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	106	108	PF00675	0.491
CLV_NRD_NRD_1	129	131	PF00675	0.682
CLV_NRD_NRD_1	145	147	PF00675	0.575
CLV_NRD_NRD_1	164	166	PF00675	0.787
CLV_NRD_NRD_1	46	48	PF00675	0.772
CLV_PCSK_KEX2_1	137	139	PF00082	0.621
CLV_PCSK_KEX2_1	145	147	PF00082	0.647
CLV_PCSK_KEX2_1	46	48	PF00082	0.772
CLV_PCSK_PC1ET2_1	137	139	PF00082	0.621
CLV_PCSK_SKI1_1	58	62	PF00082	0.577
CLV_PCSK_SKI1_1	84	88	PF00082	0.533
DEG_APCC_KENBOX_2	107	111	PF00400	0.510
DEG_Nend_UBRbox_1	1	4	PF02207	0.564
DOC_MAPK_gen_1	107	114	PF00069	0.547
DOC_PP1_RVXF_1	56	63	PF00149	0.430
DOC_USP7_MATH_1	95	99	PF00917	0.480
DOC_USP7_UBL2_3	133	137	PF12436	0.602
LIG_14-3-3_CanoR_1	152	157	PF00244	0.769
LIG_14-3-3_CanoR_1	58	63	PF00244	0.507
LIG_14-3-3_CanoR_1	65	70	PF00244	0.595
LIG_BRCT_BRCA1_1	100	104	PF00533	0.463
LIG_LIR_Nem_3	101	106	PF02991	0.472
LIG_LIR_Nem_3	61	66	PF02991	0.489
LIG_LIR_Nem_3	68	72	PF02991	0.460
LIG_MLH1_MIPbox_1	100	104	PF16413	0.463
LIG_REV1ctd_RIR_1	101	112	PF16727	0.489
LIG_SH2_CRK	90	94	PF00017	0.520
LIG_SH3_1	47	53	PF00018	0.690
LIG_SH3_2	41	46	PF14604	0.721
LIG_SH3_3	38	44	PF00018	0.725
LIG_SH3_3	47	53	PF00018	0.671
LIG_TYR_ITIM	88	93	PF00017	0.538
LIG_WRC_WIRS_1	59	64	PF05994	0.518
LIG_WRC_WIRS_1	66	71	PF05994	0.536
LIG_WW_3	162	166	PF00397	0.612
MOD_CK1_1	98	104	PF00069	0.548
MOD_GlcNHglycan	117	120	PF01048	0.289
MOD_GlcNHglycan	97	100	PF01048	0.578
MOD_GSK3_1	152	159	PF00069	0.701
MOD_Plk_4	65	71	PF00069	0.519
MOD_SUMO_rev_2	129	139	PF00179	0.675
TRG_DiLeu_BaLyEn_6	55	60	PF01217	0.498
TRG_ENDOCYTIC_2	90	93	PF00928	0.524

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A1X0NIP0	Trypanosomatidae	43%	98%
A0A3S7WXZ3	Leishmania donovani	99%	100%
A0A422P424	Trypanosoma rangeli	39%	100%
A4HD61	Leishmania braziliensis	80%	100%
E9AWJ3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4QAX7	Leishmania major	91%	100%