LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4I0K8_LEIIN
TriTrypDb:
LINF_230024200
Length:
130

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I0K8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I0K8

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 23 25 PF00675 0.568
CLV_PCSK_KEX2_1 23 25 PF00082 0.548
CLV_PCSK_SKI1_1 108 112 PF00082 0.497
DEG_Nend_UBRbox_3 1 3 PF02207 0.615
DEG_SPOP_SBC_1 30 34 PF00917 0.454
DOC_CDC14_PxL_1 41 49 PF14671 0.627
DOC_MAPK_gen_1 108 118 PF00069 0.492
DOC_USP7_MATH_1 3 7 PF00917 0.648
DOC_USP7_MATH_1 30 34 PF00917 0.635
DOC_USP7_MATH_1 36 40 PF00917 0.439
DOC_USP7_MATH_1 74 78 PF00917 0.545
DOC_USP7_MATH_1 82 86 PF00917 0.500
LIG_14-3-3_CanoR_1 35 43 PF00244 0.551
LIG_FHA_1 12 18 PF00498 0.655
LIG_LIR_Apic_2 11 16 PF02991 0.599
LIG_PTB_Apo_2 16 23 PF02174 0.561
LIG_PTB_Phospho_1 16 22 PF10480 0.560
LIG_SH2_CRK 13 17 PF00017 0.612
LIG_SH2_SRC 43 46 PF00017 0.541
LIG_SH2_STAT3 69 72 PF00017 0.376
LIG_SH2_STAT5 13 16 PF00017 0.610
LIG_SH2_STAT5 43 46 PF00017 0.541
LIG_SH3_3 39 45 PF00018 0.592
MOD_CK1_1 34 40 PF00069 0.447
MOD_CK1_1 85 91 PF00069 0.521
MOD_GlcNHglycan 5 8 PF01048 0.600
MOD_GlcNHglycan 87 90 PF01048 0.476
MOD_GlcNHglycan 98 101 PF01048 0.426
MOD_GSK3_1 30 37 PF00069 0.513
MOD_N-GLC_1 18 23 PF02516 0.608
MOD_NEK2_1 31 36 PF00069 0.472
MOD_PIKK_1 36 42 PF00454 0.672
MOD_PIKK_1 74 80 PF00454 0.466
MOD_PKA_2 34 40 PF00069 0.557
MOD_PKA_2 82 88 PF00069 0.522
MOD_Plk_1 18 24 PF00069 0.694
TRG_ENDOCYTIC_2 125 128 PF00928 0.549
TRG_ER_diArg_1 102 105 PF00400 0.501
TRG_ER_diArg_1 22 24 PF00400 0.455

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IL49 Leptomonas seymouri 60% 92%
A0A3Q8IFY5 Leishmania donovani 100% 100%
A0A3R7LAA1 Trypanosoma rangeli 36% 100%
A4HD21 Leishmania braziliensis 79% 100%
E9AWG9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 88% 100%
Q4QB02 Leishmania major 93% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS