LeishMANIAdb
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Putative dynein heavy chain

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative dynein heavy chain
Gene product:
dynein heavy chain - putative
Species:
Leishmania infantum
UniProt:
A4I0I9_LEIIN
TriTrypDb:
LINF_230022400
Length:
4757

Annotations

Annotations by Jardim et al.

Structural Proteins, dynein heavy chain

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) yes yes: 3
Silverman et al. no yes: 0
Pissara et al. yes yes: 16
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
TermNameLevelCount
GO:0005737 cytoplasm 2 9
GO:0005874 microtubule 6 10
GO:0005875 microtubule associated complex 2 12
GO:0005930 axoneme 2 1
GO:0030286 dynein complex 3 12
GO:0032991 protein-containing complex 1 12
GO:0099080 supramolecular complex 2 10
GO:0099081 supramolecular polymer 3 10
GO:0099512 supramolecular fiber 4 10
GO:0099513 polymeric cytoskeletal fiber 5 10
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Expansion

Sequence features

A4I0I9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
TermNameLevelCount
GO:0007017 microtubule-based process 2 12
GO:0007018 microtubule-based movement 3 12
GO:0009987 cellular process 1 12
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Molecular functions
TermNameLevelCount
GO:0000166 nucleotide binding 3 12
GO:0003774 cytoskeletal motor activity 1 12
GO:0003777 microtubule motor activity 2 12
GO:0003824 catalytic activity 1 1
GO:0005488 binding 1 12
GO:0005515 protein binding 2 1
GO:0005524 ATP binding 5 12
GO:0008569 minus-end-directed microtubule motor activity 3 12
GO:0016787 hydrolase activity 2 1
GO:0017076 purine nucleotide binding 4 12
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 103 107 PF00656 0.511
CLV_C14_Caspase3-7 111 115 PF00656 0.479
CLV_C14_Caspase3-7 1190 1194 PF00656 0.525
CLV_C14_Caspase3-7 125 129 PF00656 0.326
CLV_C14_Caspase3-7 1725 1729 PF00656 0.453
CLV_C14_Caspase3-7 1813 1817 PF00656 0.467
CLV_C14_Caspase3-7 1858 1862 PF00656 0.564
CLV_C14_Caspase3-7 2183 2187 PF00656 0.453
CLV_C14_Caspase3-7 2410 2414 PF00656 0.357
CLV_C14_Caspase3-7 2571 2575 PF00656 0.557
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P5Z1 Leptomonas seymouri 32% 100%
A0A0N0P6T2 Leptomonas seymouri 30% 100%
A0A0N0P8F1 Leptomonas seymouri 34% 100%
A0A0N1I0K3 Leptomonas seymouri 34% 100%
A0A0N1I4F9 Leptomonas seymouri 35% 100%
A0A0N1I9G2 Leptomonas seymouri 26% 100%
A0A0N1PCM6 Leptomonas seymouri 26% 100%
A0A0N1PCN0 Leptomonas seymouri 84% 99%
A0A0N1PCS5 Leptomonas seymouri 33% 100%
A0A0N1PF93 Leptomonas seymouri 30% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS