Hydrophilic acylated surface protein a

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

Protein of unknown function (DUF2946), putative

Species:

Leishmania infantum

UniProt:

A4I0F6_LEIIN

TriTrypDb:

Length:

168

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I0F6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I0F6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	91	95	PF00656	0.436
CLV_NRD_NRD_1	16	18	PF00675	0.495
CLV_NRD_NRD_1	166	168	PF00675	0.425
CLV_NRD_NRD_1	2	4	PF00675	0.482
CLV_NRD_NRD_1	24	26	PF00675	0.493
CLV_NRD_NRD_1	47	49	PF00675	0.458
CLV_NRD_NRD_1	9	11	PF00675	0.476
CLV_PCSK_FUR_1	22	26	PF00082	0.494
CLV_PCSK_KEX2_1	16	18	PF00082	0.495
CLV_PCSK_KEX2_1	166	168	PF00082	0.425
CLV_PCSK_KEX2_1	2	4	PF00082	0.482
CLV_PCSK_KEX2_1	22	24	PF00082	0.494
CLV_PCSK_KEX2_1	47	49	PF00082	0.458
CLV_PCSK_KEX2_1	9	11	PF00082	0.476
CLV_PCSK_SKI1_1	40	44	PF00082	0.436
DEG_Nend_UBRbox_1	1	4	PF02207	0.488
DOC_USP7_MATH_1	5	9	PF00917	0.464
DOC_USP7_MATH_1	52	56	PF00917	0.463
DOC_WW_Pin1_4	110	115	PF00397	0.420
LIG_14-3-3_CanoR_1	2	8	PF00244	0.472
LIG_14-3-3_CanoR_1	40	45	PF00244	0.437
LIG_14-3-3_CanoR_1	50	59	PF00244	0.463
LIG_14-3-3_CanoR_1	72	80	PF00244	0.454
LIG_14-3-3_CanoR_1	84	89	PF00244	0.447
LIG_FHA_1	105	111	PF00498	0.429
LIG_FHA_1	52	58	PF00498	0.463
LIG_FHA_1	95	101	PF00498	0.436
LIG_FHA_2	24	30	PF00498	0.491
LIG_FHA_2	89	95	PF00498	0.439
LIG_GBD_Chelix_1	140	148	PF00786	0.342
LIG_LIR_Gen_1	83	93	PF02991	0.444
LIG_LIR_Gen_1	99	108	PF02991	0.424
LIG_LIR_Nem_3	83	88	PF02991	0.448
LIG_LIR_Nem_3	99	104	PF02991	0.424
MOD_CK1_1	113	119	PF00069	0.407
MOD_CK1_1	46	52	PF00069	0.458
MOD_GlcNHglycan	18	21	PF01048	0.493
MOD_GlcNHglycan	54	57	PF01048	0.457
MOD_GSK3_1	1	8	PF00069	0.476
MOD_GSK3_1	106	113	PF00069	0.422
MOD_GSK3_1	23	30	PF00069	0.492
MOD_GSK3_1	80	87	PF00069	0.449
MOD_NEK2_1	1	6	PF00069	0.481
MOD_NEK2_1	104	109	PF00069	0.425
MOD_NEK2_1	28	33	PF00069	0.483
MOD_NEK2_1	34	39	PF00069	0.450
MOD_NEK2_1	61	66	PF00069	0.468
MOD_PKA_1	16	22	PF00069	0.495
MOD_PKA_1	23	29	PF00069	0.494
MOD_PKA_2	1	7	PF00069	0.479
MOD_PKA_2	15	21	PF00069	0.497
MOD_PKA_2	23	29	PF00069	0.494
MOD_PKA_2	46	52	PF00069	0.458
MOD_PKA_2	71	77	PF00069	0.455
MOD_Plk_1	28	34	PF00069	0.484
MOD_Plk_4	106	112	PF00069	0.423
MOD_Plk_4	40	46	PF00069	0.439
MOD_Plk_4	96	102	PF00069	0.432
MOD_ProDKin_1	110	116	PF00069	0.422
TRG_ER_diArg_1	1	3	PF00400	0.498
TRG_ER_diArg_1	117	120	PF00400	0.396
TRG_ER_diArg_1	166	168	PF00400	0.425
TRG_ER_diArg_1	21	24	PF00400	0.496
TRG_ER_diArg_1	47	50	PF00400	0.465