Hydrophilic acylated surface protein a

Quick info Annotations Localization Phosphorylation Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hydrophilic acylated surface protein a

Species:

Leishmania infantum

UniProt:

A4I0F2_LEIIN

TriTrypDb:

LINF_230018600

Length:

Annotations

Annotations by Jardim et al.

Plasma membrane, Hydrophilic acylated surface a HASPA1

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	yes	yes: 2
Forrest at al. (procyclic)	yes	yes: 2
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 3

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Phosphorylation

Amastigote: 23, 24, 26

Expansion

Sequence features

A4I0F2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I0F2

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	27	31	PF00656	0.830
CLV_PCSK_KEX2_1	15	17	PF00082	0.608
CLV_PCSK_PC1ET2_1	15	17	PF00082	0.608
DOC_USP7_UBL2_3	7	11	PF12436	0.803
LIG_FHA_2	22	28	PF00498	0.814
LIG_TRAF2_1	40	43	PF00917	0.628
MOD_CK1_1	3	9	PF00069	0.782
MOD_CK2_1	6	12	PF00069	0.800
MOD_GlcNHglycan	36	39	PF01048	0.645
MOD_GlcNHglycan	8	11	PF01048	0.765

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WXQ9	Leishmania donovani	99%	100%
E9AWB5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	55%	86%
P90552	Leishmania major	71%	91%

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