Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

RNA recognition motif. (a.k.a. RRM - RBD - or RNP domain)/RNA recognition motif (a.k.a. RRM - RBD - or RNP domain) - putative

Species:

Leishmania infantum

UniProt:

A4I0C3_LEIIN

TriTrypDb:

LINF_230014900

Length:

587

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I0C3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I0C3

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	7
GO:0003723	RNA binding	4	7
GO:0005488	binding	1	7
GO:0097159	organic cyclic compound binding	2	7
GO:1901363	heterocyclic compound binding	2	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	453	457	PF00656	0.749
CLV_C14_Caspase3-7	76	80	PF00656	0.699
CLV_NRD_NRD_1	287	289	PF00675	0.479
CLV_PCSK_KEX2_1	287	289	PF00082	0.536
CLV_PCSK_SKI1_1	192	196	PF00082	0.587
CLV_PCSK_SKI1_1	206	210	PF00082	0.528
DEG_SCF_FBW7_1	109	115	PF00400	0.651
DEG_SCF_FBW7_1	90	96	PF00400	0.721
DEG_SPOP_SBC_1	468	472	PF00917	0.810
DOC_CKS1_1	109	114	PF01111	0.791
DOC_CKS1_1	133	138	PF01111	0.646
DOC_CKS1_1	311	316	PF01111	0.671
DOC_CKS1_1	90	95	PF01111	0.719
DOC_MAPK_gen_1	252	261	PF00069	0.546
DOC_PP2B_LxvP_1	486	489	PF13499	0.807
DOC_PP4_FxxP_1	583	586	PF00568	0.639
DOC_PP4_MxPP_1	511	514	PF00568	0.684
DOC_USP7_MATH_1	101	105	PF00917	0.587
DOC_USP7_MATH_1	134	138	PF00917	0.648
DOC_USP7_MATH_1	145	149	PF00917	0.682
DOC_USP7_MATH_1	21	25	PF00917	0.637
DOC_USP7_MATH_1	247	251	PF00917	0.563
DOC_USP7_MATH_1	327	331	PF00917	0.611
DOC_USP7_MATH_1	35	39	PF00917	0.710
DOC_USP7_MATH_1	394	398	PF00917	0.706
DOC_USP7_MATH_1	409	413	PF00917	0.699
DOC_USP7_MATH_1	469	473	PF00917	0.707
DOC_USP7_MATH_1	499	503	PF00917	0.747
DOC_USP7_MATH_1	535	539	PF00917	0.672
DOC_USP7_MATH_1	548	552	PF00917	0.704
DOC_USP7_MATH_1	575	579	PF00917	0.647
DOC_USP7_MATH_2	323	329	PF00917	0.561
DOC_USP7_MATH_2	532	538	PF00917	0.702
DOC_WW_Pin1_4	108	113	PF00397	0.792
DOC_WW_Pin1_4	132	137	PF00397	0.653
DOC_WW_Pin1_4	24	29	PF00397	0.682
DOC_WW_Pin1_4	310	315	PF00397	0.693
DOC_WW_Pin1_4	336	341	PF00397	0.732
DOC_WW_Pin1_4	400	405	PF00397	0.698
DOC_WW_Pin1_4	456	461	PF00397	0.746
DOC_WW_Pin1_4	582	587	PF00397	0.643
DOC_WW_Pin1_4	89	94	PF00397	0.794
LIG_14-3-3_CanoR_1	105	110	PF00244	0.724
LIG_14-3-3_CanoR_1	170	180	PF00244	0.625
LIG_14-3-3_CanoR_1	519	524	PF00244	0.669
LIG_APCC_ABBA_1	258	263	PF00400	0.546
LIG_BRCT_BRCA1_1	501	505	PF00533	0.614
LIG_BRCT_BRCA1_1	577	581	PF00533	0.747
LIG_BRCT_BRCA1_1	60	64	PF00533	0.641
LIG_FHA_1	25	31	PF00498	0.549
LIG_FHA_1	281	287	PF00498	0.619
LIG_FHA_1	401	407	PF00498	0.720
LIG_FHA_1	67	73	PF00498	0.751
LIG_LIR_Apic_2	128	134	PF02991	0.655
LIG_LIR_Nem_3	11	16	PF02991	0.644
LIG_LIR_Nem_3	128	133	PF02991	0.597
LIG_LIR_Nem_3	578	584	PF02991	0.636
LIG_LIR_Nem_3	61	66	PF02991	0.747
LIG_MLH1_MIPbox_1	60	64	PF16413	0.743
LIG_Pex14_2	62	66	PF04695	0.748
LIG_PTAP_UEV_1	135	140	PF05743	0.652
LIG_SH2_CRK	131	135	PF00017	0.651
LIG_SH2_GRB2like	86	89	PF00017	0.792
LIG_SH2_STAP1	86	90	PF00017	0.792
LIG_SH2_STAT5	129	132	PF00017	0.652
LIG_SH2_STAT5	567	570	PF00017	0.684
LIG_SH2_STAT5	582	585	PF00017	0.628
LIG_SH2_STAT5	63	66	PF00017	0.749
LIG_SH3_2	136	141	PF14604	0.660
LIG_SH3_2	514	519	PF14604	0.709
LIG_SH3_3	133	139	PF00018	0.648
LIG_SH3_3	165	171	PF00018	0.791
LIG_SH3_3	294	300	PF00018	0.656
LIG_SH3_3	309	315	PF00018	0.692
LIG_SH3_3	337	343	PF00018	0.634
LIG_SH3_3	365	371	PF00018	0.699
LIG_SH3_3	438	444	PF00018	0.763
LIG_SH3_3	44	50	PF00018	0.669
LIG_SH3_3	504	510	PF00018	0.706
LIG_SH3_3	511	517	PF00018	0.694
LIG_SH3_3	87	93	PF00018	0.684
LIG_SUMO_SIM_anti_2	193	199	PF11976	0.670
LIG_WRC_WIRS_1	63	68	PF05994	0.748
LIG_WW_3	167	171	PF00397	0.506
MOD_CK1_1	108	114	PF00069	0.721
MOD_CK1_1	148	154	PF00069	0.732
MOD_CK1_1	24	30	PF00069	0.744
MOD_CK1_1	266	272	PF00069	0.546
MOD_CK1_1	379	385	PF00069	0.718
MOD_CK1_1	38	44	PF00069	0.751
MOD_CK1_1	393	399	PF00069	0.668
MOD_CK1_1	402	408	PF00069	0.648
MOD_CK1_1	410	416	PF00069	0.690
MOD_CK1_1	445	451	PF00069	0.814
MOD_CK1_1	467	473	PF00069	0.819
MOD_CK1_1	522	528	PF00069	0.663
MOD_CK1_1	555	561	PF00069	0.726
MOD_CK1_1	9	15	PF00069	0.616
MOD_GlcNHglycan	117	120	PF01048	0.683
MOD_GlcNHglycan	136	139	PF01048	0.643
MOD_GlcNHglycan	147	150	PF01048	0.684
MOD_GlcNHglycan	17	20	PF01048	0.693
MOD_GlcNHglycan	216	219	PF01048	0.346
MOD_GlcNHglycan	225	228	PF01048	0.346
MOD_GlcNHglycan	23	26	PF01048	0.727
MOD_GlcNHglycan	265	268	PF01048	0.346
MOD_GlcNHglycan	290	294	PF01048	0.593
MOD_GlcNHglycan	308	311	PF01048	0.676
MOD_GlcNHglycan	327	330	PF01048	0.596
MOD_GlcNHglycan	355	358	PF01048	0.729
MOD_GlcNHglycan	378	381	PF01048	0.684
MOD_GlcNHglycan	392	395	PF01048	0.663
MOD_GlcNHglycan	434	437	PF01048	0.797
MOD_GlcNHglycan	471	474	PF01048	0.787
MOD_GlcNHglycan	477	480	PF01048	0.675
MOD_GlcNHglycan	537	540	PF01048	0.738
MOD_GlcNHglycan	546	549	PF01048	0.631
MOD_GlcNHglycan	550	553	PF01048	0.615
MOD_GlcNHglycan	554	557	PF01048	0.548
MOD_GlcNHglycan	8	11	PF01048	0.618
MOD_GlcNHglycan	95	98	PF01048	0.720
MOD_GSK3_1	101	108	PF00069	0.667
MOD_GSK3_1	111	118	PF00069	0.499
MOD_GSK3_1	144	151	PF00069	0.688
MOD_GSK3_1	159	166	PF00069	0.727
MOD_GSK3_1	20	27	PF00069	0.745
MOD_GSK3_1	266	273	PF00069	0.546
MOD_GSK3_1	306	313	PF00069	0.696
MOD_GSK3_1	321	328	PF00069	0.682
MOD_GSK3_1	341	348	PF00069	0.644
MOD_GSK3_1	35	42	PF00069	0.740
MOD_GSK3_1	358	365	PF00069	0.749
MOD_GSK3_1	390	397	PF00069	0.752
MOD_GSK3_1	398	405	PF00069	0.673
MOD_GSK3_1	409	416	PF00069	0.691
MOD_GSK3_1	447	454	PF00069	0.730
MOD_GSK3_1	459	466	PF00069	0.714
MOD_GSK3_1	544	551	PF00069	0.790
MOD_GSK3_1	58	65	PF00069	0.661
MOD_GSK3_1	82	89	PF00069	0.733
MOD_GSK3_1	91	98	PF00069	0.633
MOD_N-GLC_1	151	156	PF02516	0.678
MOD_N-GLC_1	304	309	PF02516	0.698
MOD_N-GLC_1	390	395	PF02516	0.765
MOD_N-GLC_1	410	415	PF02516	0.464
MOD_N-GLC_1	573	578	PF02516	0.686
MOD_N-GLC_1	80	85	PF02516	0.786
MOD_N-GLC_2	268	270	PF02516	0.346
MOD_NEK2_1	362	367	PF00069	0.558
MOD_NEK2_1	39	44	PF00069	0.698
MOD_NEK2_1	398	403	PF00069	0.705
MOD_NEK2_1	414	419	PF00069	0.688
MOD_NEK2_1	447	452	PF00069	0.830
MOD_NEK2_1	477	482	PF00069	0.779
MOD_NEK2_1	573	578	PF00069	0.534
MOD_NEK2_1	62	67	PF00069	0.748
MOD_NEK2_1	82	87	PF00069	0.460
MOD_NEK2_1	95	100	PF00069	0.695
MOD_NEK2_2	346	351	PF00069	0.662
MOD_NEK2_2	58	63	PF00069	0.740
MOD_PIKK_1	299	305	PF00454	0.692
MOD_PIKK_1	477	483	PF00454	0.683
MOD_PK_1	519	525	PF00069	0.712
MOD_PKA_2	163	169	PF00069	0.793
MOD_PKA_2	223	229	PF00069	0.546
MOD_PKB_1	304	312	PF00069	0.697
MOD_Plk_1	410	416	PF00069	0.714
MOD_Plk_4	371	377	PF00069	0.726
MOD_Plk_4	402	408	PF00069	0.719
MOD_Plk_4	410	416	PF00069	0.690
MOD_Plk_4	442	448	PF00069	0.723
MOD_Plk_4	49	55	PF00069	0.728
MOD_Plk_4	58	64	PF00069	0.575
MOD_ProDKin_1	108	114	PF00069	0.792
MOD_ProDKin_1	132	138	PF00069	0.651
MOD_ProDKin_1	24	30	PF00069	0.683
MOD_ProDKin_1	310	316	PF00069	0.693
MOD_ProDKin_1	336	342	PF00069	0.727
MOD_ProDKin_1	400	406	PF00069	0.697
MOD_ProDKin_1	456	462	PF00069	0.747
MOD_ProDKin_1	89	95	PF00069	0.796
TRG_ENDOCYTIC_2	530	533	PF00928	0.675
TRG_ENDOCYTIC_2	63	66	PF00928	0.749
TRG_ER_diArg_1	286	288	PF00400	0.532

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PEZ5	Leptomonas seymouri	47%	89%
A0A3S7WXP3	Leishmania donovani	100%	100%
A4HCU2	Leishmania braziliensis	77%	100%
E9AW87	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
Q4QB91	Leishmania major	94%	100%