Small capsomere-interacting protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I090_LEIIN

TriTrypDb:

LINF_230010400

Length:

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I090

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I090

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_FUR_1	36	40	PF00082	0.557
CLV_PCSK_KEX2_1	38	40	PF00082	0.586
CLV_PCSK_PC1ET2_1	38	40	PF00082	0.564
CLV_PCSK_SKI1_1	5	9	PF00082	0.617
CLV_PCSK_SKI1_1	50	54	PF00082	0.504
CLV_PCSK_SKI1_1	64	68	PF00082	0.560
DOC_MAPK_gen_1	36	46	PF00069	0.582
DOC_PP1_RVXF_1	48	54	PF00149	0.435
LIG_FHA_1	79	85	PF00498	0.633
LIG_FHA_2	7	13	PF00498	0.603
LIG_LIR_Nem_3	93	98	PF02991	0.583
LIG_SH2_NCK_1	74	78	PF00017	0.541
LIG_SH2_SRC	22	25	PF00017	0.527
LIG_SH2_STAP1	62	66	PF00017	0.553
LIG_SH2_STAT5	78	81	PF00017	0.607
MOD_CK1_1	30	36	PF00069	0.560
MOD_CK1_1	83	89	PF00069	0.661
MOD_CK2_1	6	12	PF00069	0.610
MOD_GSK3_1	79	86	PF00069	0.665
MOD_NEK2_1	27	32	PF00069	0.641
MOD_NEK2_2	62	67	PF00069	0.542
MOD_PKA_2	27	33	PF00069	0.667
TRG_Pf-PMV_PEXEL_1	64	69	PF00026	0.547

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HZM7	Leptomonas seymouri	65%	100%
A0A3S7WXN8	Leishmania donovani	99%	100%
A4HCR5	Leishmania braziliensis	80%	100%
C9ZV07	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	50%	100%
E9AW54	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
Q4QBC3	Leishmania major	93%	100%
V5D8H0	Trypanosoma cruzi	56%	100%