Putative NADP-dependent alcohol dehydrogenase

Quick info Annotations Localization Abundance Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

NADP-dependent alcohol dehydrogenase - putative

Species:

Leishmania infantum

UniProt:

A4I076_LEIIN

TriTrypDb:

LINF_230009000

Length:

352

Annotations

Annotations by Jardim et al.

Oxidoreductase, NADP-dependent alcohol dehydrogenase

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	yes	yes: 4
Forrest at al. (procyclic)	yes	yes: 4
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 15

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 5

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 10

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Abundance

Amastigote (protein)


Source	Evidence on protein	Close homologs
Pescher et al. (upgregulation)	no	yes: 0

Promastigote and amastigote


Source	Evidence on protein	Close homologs
Lahav et al. - mRNA - Protein

Expansion

Sequence features

A4I076

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I076

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	10
GO:0004022	alcohol dehydrogenase (NAD+) activity	6	6
GO:0005488	binding	1	10
GO:0008270	zinc ion binding	6	10
GO:0016491	oxidoreductase activity	2	10
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	3	6
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	4	6
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	5	6
GO:0043167	ion binding	2	10
GO:0043169	cation binding	3	10
GO:0046872	metal ion binding	4	10
GO:0046914	transition metal ion binding	5	10

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	145	149	PF00656	0.405
CLV_NRD_NRD_1	24	26	PF00675	0.407
CLV_NRD_NRD_1	282	284	PF00675	0.335
CLV_PCSK_KEX2_1	24	26	PF00082	0.408
CLV_PCSK_KEX2_1	282	284	PF00082	0.365
CLV_PCSK_KEX2_1	350	352	PF00082	0.596
CLV_PCSK_PC1ET2_1	350	352	PF00082	0.408
CLV_PCSK_SKI1_1	265	269	PF00082	0.408
DOC_MAPK_gen_1	175	185	PF00069	0.431
DOC_MAPK_gen_1	79	88	PF00069	0.317
DOC_MAPK_MEF2A_6	254	262	PF00069	0.407
DOC_MAPK_RevD_3	267	283	PF00069	0.401
DOC_SPAK_OSR1_1	341	345	PF12202	0.341
DOC_WW_Pin1_4	123	128	PF00397	0.416
DOC_WW_Pin1_4	164	169	PF00397	0.334
LIG_14-3-3_CanoR_1	332	342	PF00244	0.434
LIG_deltaCOP1_diTrp_1	51	58	PF00928	0.318
LIG_FHA_1	237	243	PF00498	0.424
LIG_FHA_1	257	263	PF00498	0.239
LIG_FHA_1	300	306	PF00498	0.453
LIG_FHA_1	313	319	PF00498	0.372
LIG_FHA_2	118	124	PF00498	0.404
LIG_FHA_2	225	231	PF00498	0.416
LIG_LIR_Gen_1	328	338	PF02991	0.384
LIG_LIR_Nem_3	126	132	PF02991	0.388
LIG_LIR_Nem_3	164	169	PF02991	0.334
LIG_LIR_Nem_3	337	343	PF02991	0.373
LIG_LIR_Nem_3	56	61	PF02991	0.341
LIG_MYND_1	277	281	PF01753	0.352
LIG_PTB_Apo_2	32	39	PF02174	0.244
LIG_PTB_Phospho_1	32	38	PF10480	0.244
LIG_SH2_CRK	340	344	PF00017	0.361
LIG_SH2_CRK	38	42	PF00017	0.398
LIG_SH2_STAP1	132	136	PF00017	0.316
LIG_SH2_STAP1	330	334	PF00017	0.371
LIG_SH2_STAT5	108	111	PF00017	0.341
LIG_SH2_STAT5	38	41	PF00017	0.352
LIG_SH3_2	278	283	PF14604	0.401
LIG_SH3_3	141	147	PF00018	0.416
LIG_SH3_3	266	272	PF00018	0.316
LIG_SH3_3	275	281	PF00018	0.316
LIG_SH3_3	56	62	PF00018	0.316
LIG_SUMO_SIM_anti_2	239	246	PF11976	0.457
LIG_SUMO_SIM_par_1	142	148	PF11976	0.341
LIG_SUMO_SIM_par_1	258	263	PF11976	0.421
LIG_TYR_ITIM	169	174	PF00017	0.482
LIG_TYR_ITIM	338	343	PF00017	0.380
LIG_TYR_ITIM	36	41	PF00017	0.398
LIG_UBA3_1	257	265	PF00899	0.401
LIG_WRC_WIRS_1	163	168	PF05994	0.434
MOD_CDC14_SPxK_1	167	170	PF00782	0.377
MOD_CDK_SPxK_1	164	170	PF00069	0.368
MOD_CK1_1	12	18	PF00069	0.487
MOD_CK1_1	75	81	PF00069	0.359
MOD_CK2_1	12	18	PF00069	0.437
MOD_CK2_1	224	230	PF00069	0.397
MOD_GlcNHglycan	11	14	PF01048	0.498
MOD_GSK3_1	113	120	PF00069	0.409
MOD_GSK3_1	232	239	PF00069	0.390
MOD_GSK3_1	243	250	PF00069	0.303
MOD_GSK3_1	68	75	PF00069	0.390
MOD_N-GLC_1	117	122	PF02516	0.409
MOD_N-GLC_1	312	317	PF02516	0.486
MOD_N-GLC_2	307	309	PF02516	0.401
MOD_NEK2_1	142	147	PF00069	0.341
MOD_NEK2_1	206	211	PF00069	0.318
MOD_NEK2_1	91	96	PF00069	0.316
MOD_NEK2_2	201	206	PF00069	0.310
MOD_OFUCOSY	90	95	PF10250	0.316
MOD_PIKK_1	117	123	PF00454	0.359
MOD_PIKK_1	299	305	PF00454	0.311
MOD_PKA_1	175	181	PF00069	0.430
MOD_PKA_2	207	213	PF00069	0.401
MOD_Plk_1	201	207	PF00069	0.341
MOD_Plk_2-3	319	325	PF00069	0.314
MOD_Plk_4	201	207	PF00069	0.316
MOD_ProDKin_1	123	129	PF00069	0.416
MOD_ProDKin_1	164	170	PF00069	0.343
MOD_SUMO_for_1	349	352	PF00179	0.474
MOD_SUMO_rev_2	119	127	PF00179	0.371
MOD_SUMO_rev_2	209	219	PF00179	0.467
MOD_SUMO_rev_2	261	267	PF00179	0.424
TRG_DiLeu_BaEn_1	301	306	PF01217	0.457
TRG_DiLeu_BaEn_4	214	220	PF01217	0.380
TRG_DiLeu_BaLyEn_6	154	159	PF01217	0.330
TRG_ENDOCYTIC_2	171	174	PF00928	0.411
TRG_ENDOCYTIC_2	330	333	PF00928	0.345
TRG_ENDOCYTIC_2	340	343	PF00928	0.318
TRG_ENDOCYTIC_2	38	41	PF00928	0.398
TRG_ER_diArg_1	281	283	PF00400	0.401
TRG_NES_CRM1_1	231	245	PF08389	0.416
TRG_NES_CRM1_1	252	263	PF08389	0.416
TRG_Pf-PMV_PEXEL_1	103	107	PF00026	0.457
TRG_Pf-PMV_PEXEL_1	332	337	PF00026	0.440

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A075TMP0	Penicillium expansum	34%	100%
A0A0C5DM37	Catharanthus roseus	24%	94%
A0A0N1I9E8	Leptomonas seymouri	22%	100%
A0A0N1PAV7	Leptomonas seymouri	64%	100%
A0A0N1PBK4	Leptomonas seymouri	81%	100%
A0A0N1PDX1	Leptomonas seymouri	23%	100%
A0A0S4IT20	Bodo saltans	25%	100%
A0A0S4JG37	Bodo saltans	55%	94%
A0A161CAI1	Catharanthus roseus	39%	99%
A0A1B1FHP3	Catharanthus roseus	42%	96%
A0A1X0NYI6	Trypanosomatidae	63%	100%
A0A2P1GIW4	Catharanthus roseus	44%	99%
A0A2U1Q018	Artemisia annua	23%	93%
A0A3Q8IEG7	Leishmania donovani	100%	100%
A0A3S7X2E3	Leishmania donovani	23%	100%
A0B459	Burkholderia cenocepacia (strain HI2424)	28%	100%
A0KQV6	Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049)	29%	100%
A0L2Q3	Shewanella sp. (strain ANA-3)	28%	100%
A0Q5K3	Francisella tularensis subsp. novicida (strain U112)	28%	100%
A1AHF3	Escherichia coli O1:K1 / APEC	31%	100%
A1CFL1	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	33%	91%
A1CFY8	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	30%	98%
A1D9C9	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	29%	98%
A1JHX8	Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)	29%	100%
A1L4Y2	Arabidopsis thaliana	25%	89%
A1RE07	Shewanella sp. (strain W3-18-1)	29%	100%
A1S1Q3	Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)	29%	100%
A1SVW5	Psychromonas ingrahamii (strain 37)	28%	100%
A1UXP8	Burkholderia mallei (strain SAVP1)	28%	100%
A2QY54	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	28%	98%
A2RZW5	Burkholderia mallei (strain NCTC 10229)	28%	100%
A2XAZ3	Oryza sativa subsp. indica	25%	92%
A3CYN0	Shewanella baltica (strain OS155 / ATCC BAA-1091)	30%	100%
A3MAC8	Burkholderia mallei (strain NCTC 10247)	28%	100%
A3NF91	Burkholderia pseudomallei (strain 668)	28%	100%
A3P139	Burkholderia pseudomallei (strain 1106a)	28%	100%
A3QJC8	Shewanella loihica (strain ATCC BAA-1088 / PV-4)	30%	100%
A4FND4	Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338)	30%	100%
A4HCQ1	Leishmania braziliensis	85%	100%
A4HHB3	Leishmania braziliensis	23%	100%
A4I4G0	Leishmania infantum	23%	100%
A4IZ92	Francisella tularensis subsp. tularensis (strain WY96-3418)	27%	100%
A4JKG7	Burkholderia vietnamiensis (strain G4 / LMG 22486)	29%	100%
A4SHB7	Aeromonas salmonicida (strain A449)	29%	100%
A4TSC6	Yersinia pestis (strain Pestoides F)	29%	100%
A4W529	Enterobacter sp. (strain 638)	30%	100%
A4YCC5	Shewanella putrefaciens (strain CN-32 / ATCC BAA-453)	28%	100%
A4YGN0	Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)	30%	98%
A4YGN2	Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)	25%	100%
A5F0N6	Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)	30%	100%
A5IGK7	Legionella pneumophila (strain Corby)	28%	100%
A6TFL2	Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)	31%	100%
A6UBM6	Sinorhizobium medicae (strain WSM419)	31%	100%
A6W1W3	Marinomonas sp. (strain MWYL1)	30%	100%
A6WUG6	Shewanella baltica (strain OS185)	29%	100%
A7FCU5	Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)	29%	100%
A7HEI5	Anaeromyxobacter sp. (strain Fw109-5)	31%	100%
A7MID0	Cronobacter sakazakii (strain ATCC BAA-894)	31%	100%
A7NDM9	Francisella tularensis subsp. holarctica (strain FTNF002-00 / FTA)	27%	100%
A7ZTH0	Escherichia coli O139:H28 (strain E24377A / ETEC)	30%	100%
A8A681	Escherichia coli O9:H4 (strain HS)	31%	100%
A8ARK6	Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)	30%	100%
A8FPE0	Shewanella sediminis (strain HAW-EB3)	29%	100%
A8GLC6	Serratia proteamaculans (strain 568)	29%	100%
A8GYP8	Shewanella pealeana (strain ATCC 700345 / ANG-SQ1)	30%	100%
A9AR24	Burkholderia multivorans (strain ATCC 17616 / 249)	28%	100%
A9CES3	Agrobacterium fabrum (strain C58 / ATCC 33970)	27%	100%
A9KET6	Coxiella burnetii (strain Dugway 5J108-111)	28%	100%
A9KWY0	Shewanella baltica (strain OS195)	30%	100%
A9MKQ8	Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)	31%	100%
A9MVL0	Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)	31%	100%
A9NA21	Coxiella burnetii (strain RSA 331 / Henzerling II)	28%	100%
A9R685	Yersinia pestis bv. Antiqua (strain Angola)	29%	100%
B0RU31	Xanthomonas campestris pv. campestris (strain B100)	29%	100%
B0TNM4	Shewanella halifaxensis (strain HAW-EB4)	30%	100%
B0TYR8	Francisella philomiragia subsp. philomiragia (strain ATCC 25017 / FSC 153 / O#319-036)	28%	100%
B0YC65	Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163)	29%	98%
B1IZH4	Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks)	31%	100%
B1JQW2	Yersinia pseudotuberculosis serotype O:3 (strain YPIII)	29%	100%
B1K269	Burkholderia cenocepacia (strain MC0-3)	28%	100%
B1KL24	Shewanella woodyi (strain ATCC 51908 / MS32)	29%	100%
B1LK55	Escherichia coli (strain SMS-3-5 / SECEC)	31%	100%
B1VWE7	Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)	28%	100%
B1X950	Escherichia coli (strain K12 / DH10B)	31%	100%
B1YXP0	Burkholderia ambifaria (strain MC40-6)	28%	100%
B2FQN4	Stenotrophomonas maltophilia (strain K279a)	30%	100%
B2JPU0	Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 / STM815)	29%	100%
B2JYP4	Yersinia pseudotuberculosis serotype IB (strain PB1/+)	29%	100%
B2NI93	Carpoglyphus lactis	25%	93%
B2SDJ2	Francisella tularensis subsp. mediasiatica (strain FSC147)	27%	100%
B2T7X5	Paraburkholderia phytofirmans (strain DSM 17436 / LMG 22146 / PsJN)	29%	100%
B2U5D5	Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)	31%	100%
B3PUI4	Rhizobium etli (strain CIAT 652)	29%	100%
B4EFZ7	Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610)	28%	100%
B4F134	Proteus mirabilis (strain HI4320)	30%	100%
B4S298	Alteromonas mediterranea (strain DSM 17117 / CIP 110805 / LMG 28347 / Deep ecotype)	30%	100%
B4SXB9	Salmonella newport (strain SL254)	31%	100%
B4T9A1	Salmonella heidelberg (strain SL476)	31%	100%
B4TZV9	Salmonella schwarzengrund (strain CVM19633)	31%	100%
B4UMJ1	Anaeromyxobacter sp. (strain K)	31%	100%
B5BHZ1	Salmonella paratyphi A (strain AKU_12601)	31%	100%
B5ETJ6	Aliivibrio fischeri (strain MJ11)	29%	100%
B5EXC3	Salmonella agona (strain SL483)	31%	100%
B5FLI6	Salmonella dublin (strain CT_02021853)	31%	100%
B5R5E1	Salmonella enteritidis PT4 (strain P125109)	31%	100%
B5RGH0	Salmonella gallinarum (strain 287/91 / NCTC 13346)	30%	100%
B5XTI4	Klebsiella pneumoniae (strain 342)	31%	100%
B5YWB7	Escherichia coli O157:H7 (strain EC4115 / EHEC)	31%	100%
B5ZXE7	Rhizobium leguminosarum bv. trifolii (strain WSM2304)	32%	100%
B6ESA4	Aliivibrio salmonicida (strain LFI1238)	29%	100%
B6I3J6	Escherichia coli (strain SE11)	31%	100%
B6J2S1	Coxiella burnetii (strain CbuG_Q212)	28%	100%
B6YTJ5	Thermococcus onnurineus (strain NA1)	25%	100%
B7L742	Escherichia coli (strain 55989 / EAEC)	31%	100%
B7LVH6	Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73)	31%	100%
B7M4A3	Escherichia coli O8 (strain IAI1)	31%	100%
B7MFI0	Escherichia coli O45:K1 (strain S88 / ExPEC)	31%	100%
B7N1S0	Escherichia coli O81 (strain ED1a)	31%	100%
B7NES3	Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)	31%	100%
B7NPC5	Escherichia coli O7:K1 (strain IAI39 / ExPEC)	31%	100%
B7ULH2	Escherichia coli O127:H6 (strain E2348/69 / EPEC)	31%	100%
B7VR52	Vibrio atlanticus (strain LGP32)	28%	100%
B8EDS6	Shewanella baltica (strain OS223)	30%	100%
B8J714	Anaeromyxobacter dehalogenans (strain 2CP-1 / ATCC BAA-258)	29%	100%
B9J738	Agrobacterium radiobacter (strain K84 / ATCC BAA-868)	31%	100%
C0Q1V0	Salmonella paratyphi C (strain RKS4594)	31%	100%
C0SPA5	Bacillus subtilis (strain 168)	51%	100%
C1D195	Deinococcus deserti (strain DSM 17065 / CIP 109153 / LMG 22923 / VCD115)	30%	100%
C3LWF0	Vibrio cholerae serotype O1 (strain M66-2)	30%	100%
C3MFH1	Sinorhizobium fredii (strain NBRC 101917 / NGR234)	30%	100%
C4ZXK8	Escherichia coli (strain K12 / MC4100 / BW2952)	31%	100%
C5BB99	Edwardsiella ictaluri (strain 93-146)	30%	100%
C5FTT1	Arthroderma otae (strain ATCC MYA-4605 / CBS 113480)	30%	99%
C6DIA7	Pectobacterium carotovorum subsp. carotovorum (strain PC1)	29%	100%
E1ACQ9	Aspergillus sp. (strain MF297-2)	34%	100%
E9ADV9	Leishmania major	23%	100%
E9ALX1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	100%
E9AW40	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
E9B3N0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
F2Z678	Yarrowia lipolytica (strain CLIB 122 / E 150)	26%	100%
H1ZV38	Castellaniella defragrans	28%	94%
K4BW79	Solanum lycopersicum	27%	91%
O00097	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	28%	100%
O06012	Bacillus subtilis (strain 168)	30%	93%
O07737	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	27%	92%
O13309	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	28%	100%
O22380	Lolium perenne	45%	98%
O24562	Zea mays	45%	96%
O31186	Rhizobium meliloti (strain 1021)	35%	100%
O34268	Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)	29%	100%
O34788	Bacillus subtilis (strain 168)	25%	100%
O35045	Bacillus subtilis (strain 168)	26%	100%
O42909	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	25%	100%
O45687	Caenorhabditis elegans	26%	100%
O46649	Oryctolagus cuniculus	26%	93%
O46650	Oryctolagus cuniculus	25%	93%
O49482	Arabidopsis thaliana	45%	99%
O58389	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)	27%	100%
O64969	Eucalyptus globulus	46%	99%
O65621	Arabidopsis thaliana	46%	97%
O74540	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	26%	93%
O74685	Komagataella pastoris	29%	93%
O82035	Picea abies	46%	99%
O82056	Saccharum officinarum	45%	96%
O82515	Medicago sativa	51%	98%
O94038	Candida albicans (strain SC5314 / ATCC MYA-2876)	31%	100%
O94564	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	25%	100%
O97959	Papio hamadryas	29%	94%
P00325	Homo sapiens	29%	94%
P00326	Homo sapiens	29%	94%
P00329	Mus musculus	27%	94%
P00330	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	28%	100%
P00331	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	28%	100%
P00332	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	27%	100%
P00333	Zea mays	25%	93%
P04707	Zea mays	25%	93%
P05336	Hordeum vulgare	24%	93%
P06525	Arabidopsis thaliana	24%	93%
P06757	Rattus norvegicus	26%	94%
P07246	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	29%	94%
P07327	Homo sapiens	29%	94%
P07754	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	25%	100%
P07846	Ovis aries	28%	99%
P07913	Escherichia coli (strain K12)	31%	100%
P08319	Homo sapiens	26%	93%
P08843	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	24%	100%
P0A4X1	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	54%	100%
P0A9S3	Escherichia coli (strain K12)	27%	100%
P0A9S4	Escherichia coli O157:H7	27%	100%
P0CH36	Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)	54%	100%
P0CH37	Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)	54%	100%
P0CL53	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	25%	92%
P0DMQ6	Gallus gallus	29%	99%
P0DOW0	Sulfobacillus thermosulfidooxidans (strain DSM 9293 / VKM B-1269 / AT-1)	27%	100%
P10848	Hordeum vulgare	25%	93%
P11766	Homo sapiens	28%	94%
P12311	Geobacillus stearothermophilus	33%	100%
P12711	Rattus norvegicus	28%	94%
P13603	Trifolium repens	26%	93%
P14139	Papio hamadryas	30%	94%
P14219	Cenchrus americanus	25%	93%
P14673	Solanum tuberosum	27%	93%
P14674	Solanum tuberosum	27%	93%
P14675	Solanum tuberosum	27%	93%
P14941	Thermoanaerobacter brockii	30%	100%
P17648	Fragaria ananassa	27%	93%
P19631	Coturnix japonica	27%	94%
P19854	Equus caballus	29%	94%
P20368	Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)	28%	100%
P20369	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	28%	100%
P22144	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	28%	97%
P22797	Pelophylax perezi	25%	94%
P23991	Gallus gallus	26%	94%
P25377	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	36%	98%
P25405	Saara hardwickii	27%	94%
P25406	Saara hardwickii	26%	94%
P26325	Gadus morhua subsp. callarias	28%	94%
P27250	Escherichia coli (strain K12)	34%	100%
P27867	Rattus norvegicus	28%	99%
P28032	Solanum lycopersicum	26%	93%
P28469	Macaca mulatta	28%	94%
P28474	Mus musculus	28%	94%
P30359	Nicotiana tabacum	44%	99%
P30360	Nicotiana tabacum	43%	99%
P31655	Eucalyptus gunnii	46%	99%
P31656	Medicago sativa	45%	98%
P31657	Populus deltoides	46%	99%
P32771	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	29%	91%
P33010	Pseudomonas sp.	29%	100%
P35497	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	29%	99%
P38113	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	29%	100%
P39346	Escherichia coli (strain K12)	24%	100%
P39400	Escherichia coli (strain K12)	25%	100%
P39451	Escherichia coli (strain K12)	27%	100%
P39462	Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	30%	100%
P39849	Pseudomonas putida	27%	96%
P40394	Homo sapiens	26%	91%
P41637	Pinus taeda	46%	99%
P41680	Peromyscus maniculatus	26%	94%
P41682	Rattus norvegicus	26%	94%
P41747	Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 / SRRC 167)	25%	100%
P42327	Geobacillus stearothermophilus	32%	100%
P42328	Geobacillus stearothermophilus	34%	100%
P42495	Aralia cordata	48%	98%
P42734	Arabidopsis thaliana	49%	98%
P42754	Petroselinum crispum	51%	100%
P43067	Candida albicans	27%	100%
P46415	Drosophila melanogaster	28%	93%
P47734	Methylobacter marinus	25%	90%
P48523	Arabidopsis thaliana	45%	96%
P49383	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	27%	100%
P49384	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	29%	94%
P49385	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	30%	94%
P49645	Apteryx australis	26%	94%
P50381	Sulfolobus sp. (strain RC3)	30%	100%
P50746	Eucalyptus botryoides	45%	99%
P54202	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	30%	96%
P59409	Shigella flexneri	31%	100%
P59410	Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)	29%	100%
P73138	Synechocystis sp. (strain PCC 6803 / Kazusa)	30%	95%
P74721	Synechocystis sp. (strain PCC 6803 / Kazusa)	36%	100%
P75691	Escherichia coli (strain K12)	54%	100%
P77280	Escherichia coli (strain K12)	29%	100%
P77539	Escherichia coli (strain K12)	28%	98%
P78870	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	26%	93%
P80094	Amycolatopsis methanolica	28%	98%
P80338	Struthio camelus	26%	94%
P80360	Myxine glutinosa	28%	94%
P80468	Struthio camelus	22%	93%
P80572	Pisum sativum	26%	93%
P81431	Octopus vulgaris	28%	93%
P86883	Columba livia	25%	94%
P86884	Scyliorhinus canicula	26%	94%
P86885	Mesocricetus auratus	27%	94%
P93257	Mesembryanthemum crystallinum	50%	98%
P9WQC0	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	27%	100%
P9WQC1	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	27%	100%
P9WQC2	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	29%	96%
P9WQC3	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	29%	96%
P9WQC4	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	54%	100%
P9WQC5	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	54%	100%
P9WQC6	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	31%	94%
P9WQC7	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	31%	94%
Q00796	Homo sapiens	29%	99%
Q02912	Bombyx mori	27%	100%
Q02971	Arabidopsis thaliana	48%	99%
Q02972	Arabidopsis thaliana	50%	98%
Q02BT1	Solibacter usitatus (strain Ellin6076)	28%	100%
Q03505	Oryctolagus cuniculus	27%	94%
Q04894	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	38%	98%
Q06004	Bacillus subtilis (strain 168)	30%	100%
Q06099	Candida maltosa	25%	92%
Q07288	Kluyveromyces marxianus	28%	100%
Q07786	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	29%	99%
Q07W50	Shewanella frigidimarina (strain NCIMB 400)	29%	100%
Q08350	Picea abies	46%	99%
Q0B5Q1	Burkholderia ambifaria (strain ATCC BAA-244 / AMMD)	28%	100%
Q0BKV5	Francisella tularensis subsp. holarctica (strain OSU18)	27%	100%
Q0CWQ2	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	28%	100%
Q0HDA3	Shewanella sp. (strain MR-4)	28%	100%
Q0HPI5	Shewanella sp. (strain MR-7)	28%	100%
Q0ITW7	Oryza sativa subsp. japonica	25%	93%
Q0J6T3	Oryza sativa subsp. japonica	48%	99%
Q0JA75	Oryza sativa subsp. japonica	44%	93%
Q0SYE5	Shigella flexneri serotype 5b (strain 8401)	31%	100%
Q0TBJ0	Escherichia coli O6:K15:H31 (strain 536 / UPEC)	31%	100%
Q0V7W6	Arabidopsis thaliana	26%	90%
Q0W5A6	Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50)	25%	98%
Q10PS6	Oryza sativa subsp. japonica	43%	97%
Q11L77	Chelativorans sp. (strain BNC1)	31%	100%
Q13SG2	Paraburkholderia xenovorans (strain LB400)	29%	100%
Q14IB6	Francisella tularensis subsp. tularensis (strain FSC 198)	27%	100%
Q15SS1	Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)	26%	100%
Q15ZU4	Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)	30%	100%
Q17334	Caenorhabditis elegans	27%	100%
Q17335	Caenorhabditis elegans	28%	92%
Q1BK24	Burkholderia cenocepacia (strain AU 1054)	28%	100%
Q1C278	Yersinia pestis bv. Antiqua (strain Antiqua)	29%	100%
Q1CD13	Yersinia pestis bv. Antiqua (strain Nepal516)	29%	100%
Q1MDT5	Rhizobium leguminosarum bv. viciae (strain 3841)	32%	100%
Q1PSI9	Vitis vinifera	28%	96%
Q1R4X4	Escherichia coli (strain UTI89 / UPEC)	31%	100%
Q2A282	Francisella tularensis subsp. holarctica (strain LVS)	27%	100%
Q2FJ31	Staphylococcus aureus (strain USA300)	30%	100%
Q2G0G1	Staphylococcus aureus (strain NCTC 8325 / PS 47)	30%	100%
Q2IJN4	Anaeromyxobacter dehalogenans (strain 2CP-C)	30%	100%
Q2K618	Rhizobium etli (strain CFN 42 / ATCC 51251)	31%	100%
Q2KNL5	Ocimum basilicum	46%	99%
Q2KNL6	Ocimum basilicum	49%	98%
Q2MF22	Streptoalloteichus tenebrarius (strain ATCC 17920 / DSM 40477 / JCM 4838 / CBS 697.72 / NBRC 16175 / NCIMB 11028 / NRRL B-12390 / A12253. 1)	25%	100%
Q2MF72	Streptomyces lividus	24%	100%
Q2MFP3	Streptomyces paromomycinus	25%	100%
Q2NZP2	Xanthomonas oryzae pv. oryzae (strain MAFF 311018)	29%	100%
Q2R114	Oryza sativa subsp. japonica	42%	99%
Q2R8Z5	Oryza sativa subsp. japonica	25%	93%
Q2T9E1	Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264)	28%	100%
Q2YSX0	Staphylococcus aureus (strain bovine RF122 / ET3-1)	30%	100%
Q31V06	Shigella boydii serotype 4 (strain Sb227)	31%	100%
Q329N8	Shigella dysenteriae serotype 1 (strain Sd197)	30%	100%
Q337Y2	Oryza sativa subsp. japonica	47%	96%
Q38707	Apium graveolens	49%	96%
Q38ZS8	Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)	28%	100%
Q3BWT0	Xanthomonas campestris pv. vesicatoria (strain 85-10)	29%	100%
Q3IHW0	Pseudoalteromonas translucida (strain TAC 125)	30%	100%
Q3JID4	Burkholderia pseudomallei (strain 1710b)	28%	100%
Q3YVY1	Shigella sonnei (strain Ss046)	30%	100%
Q40976	Pinus radiata	46%	99%
Q42726	Eucalyptus gunnii	45%	99%
Q43137	Stylosanthes humilis	50%	99%
Q43138	Stylosanthes humilis	44%	97%
Q45604	Bacillus subtilis (strain 168)	27%	86%
Q48AM4	Colwellia psychrerythraea (strain 34H / ATCC BAA-681)	28%	100%
Q4J781	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)	28%	100%
Q4QBD8	Leishmania major	98%	100%
Q4R0J7	Uromyces fabae	27%	100%
Q4R0W1	Streptomyces ribosidificus	25%	100%
Q4R1E8	Oryza sativa subsp. indica	25%	93%
Q4R639	Macaca fascicularis	30%	99%
Q4URI9	Xanthomonas campestris pv. campestris (strain 8004)	29%	100%
Q4WAU7	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	29%	98%
Q52998	Rhizobium meliloti (strain 1021)	31%	100%
Q53U21	Streptomyces fradiae	25%	100%
Q54TC2	Dictyostelium discoideum	25%	93%
Q57517	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	27%	100%
Q57IC5	Salmonella choleraesuis (strain SC-B67)	31%	100%
Q58D31	Bos taurus	28%	99%
Q59545	Morganella morganii	25%	100%
Q59I44	Burkholderia sp.	27%	100%
Q5ARL6	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	29%	98%
Q5E0F9	Aliivibrio fischeri (strain ATCC 700601 / ES114)	29%	100%
Q5GN51	Aspergillus niger	28%	98%
Q5GWI3	Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85)	29%	100%
Q5HI63	Staphylococcus aureus (strain COL)	30%	100%
Q5HRD6	Staphylococcus epidermidis (strain ATCC 35984 / RP62A)	30%	100%
Q5JI69	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)	26%	100%
Q5LN53	Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)	27%	100%
Q5NGW4	Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)	27%	100%
Q5PC07	Salmonella paratyphi A (strain ATCC 9150 / SARB42)	31%	100%
Q5QUN8	Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR)	27%	100%
Q5R1W2	Pan troglodytes	29%	94%
Q5R5F3	Pongo abelii	30%	99%
Q5RBP7	Pongo abelii	29%	94%
Q5SKS4	Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)	25%	100%
Q5UQG2	Acanthamoeba polyphaga mimivirus	40%	83%
Q5WYJ7	Legionella pneumophila (strain Lens)	28%	100%
Q5X748	Legionella pneumophila (strain Paris)	28%	100%
Q5ZXM9	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	28%	100%
Q62EL5	Burkholderia mallei (strain ATCC 23344)	28%	100%
Q63PD9	Burkholderia pseudomallei (strain K96243)	28%	100%
Q64413	Geomys bursarius	27%	94%
Q64415	Geomys knoxjonesi	27%	94%
Q64437	Mus musculus	25%	94%
Q64442	Mus musculus	29%	99%
Q64563	Rattus norvegicus	26%	93%
Q65JE7	Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46)	26%	100%
Q66GC5	Yersinia pseudotuberculosis serotype I (strain IP32953)	29%	100%
Q67N85	Symbiobacterium thermophilum (strain T / IAM 14863)	25%	100%
Q6AAR3	Cutibacterium acnes (strain DSM 16379 / KPA171202)	29%	100%
Q6DAT5	Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)	29%	98%
Q6ERW5	Oryza sativa subsp. japonica	45%	97%
Q6ERW7	Oryza sativa subsp. japonica	44%	80%
Q6ERW9	Oryza sativa subsp. japonica	44%	81%
Q6ERX1	Oryza sativa subsp. japonica	46%	98%
Q6GBM4	Staphylococcus aureus (strain MSSA476)	30%	100%
Q6GJ63	Staphylococcus aureus (strain MRSA252)	30%	100%
Q6L743	Streptomyces kanamyceticus	27%	100%
Q6LRD9	Photobacterium profundum (strain SS9)	29%	100%
Q6MD15	Protochlamydia amoebophila (strain UWE25)	26%	100%
Q6V4H0	Catharanthus roseus	50%	98%
Q6XQ67	Saccharomyces pastorianus	29%	100%
Q6ZHS4	Oryza sativa subsp. japonica	45%	97%
Q70KF0	Micromonospora echinospora	26%	100%
Q72L62	Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)	26%	100%
Q75ZX4	Oryza sativa subsp. indica	25%	93%
Q7A742	Staphylococcus aureus (strain N315)	30%	100%
Q7MFL5	Vibrio vulnificus (strain YJ016)	29%	100%
Q7MY48	Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)	30%	100%
Q7NXH5	Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)	32%	100%
Q7U1B9	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	31%	94%
Q7XWU3	Oryza sativa subsp. japonica	47%	98%
Q82MN2	Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)	28%	100%
Q83F39	Coxiella burnetii (strain RSA 493 / Nine Mile phase I)	28%	100%
Q86ZV0	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	27%	98%
Q8CQ56	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	30%	100%
Q8D442	Vibrio vulnificus (strain CMCP6)	29%	100%
Q8E8J1	Shewanella oneidensis (strain MR-1)	28%	100%
Q8FCA2	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	31%	100%
Q8GIX7	Moraxella sp. (strain TAE123)	33%	100%
Q8H859	Oryza sativa subsp. japonica	43%	99%
Q8KQL2	Enterococcus avium	29%	100%
Q8NXU1	Staphylococcus aureus (strain MW2)	30%	100%
Q8PNN2	Xanthomonas axonopodis pv. citri (strain 306)	29%	100%
Q8R7K0	Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4)	29%	100%
Q8U259	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)	28%	100%
Q8U7Y1	Agrobacterium fabrum (strain C58 / ATCC 33970)	26%	100%
Q8VZ49	Arabidopsis thaliana	23%	93%
Q8XEJ1	Escherichia coli O157:H7	31%	100%
Q8Z2F4	Salmonella typhi	31%	100%
Q8ZJN2	Yersinia pestis	29%	100%
Q8ZL52	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	31%	100%
Q92MT4	Rhizobium meliloti (strain 1021)	28%	100%
Q96533	Arabidopsis thaliana	27%	93%
Q96XE0	Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)	31%	100%
Q975C8	Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)	25%	100%
Q97U21	Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	26%	98%
Q983J7	Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099)	32%	100%
Q98D10	Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099)	29%	100%
Q99W07	Staphylococcus aureus (strain Mu50 / ATCC 700699)	30%	100%
Q9CAI3	Arabidopsis thaliana	45%	99%
Q9FH04	Arabidopsis thaliana	27%	90%
Q9FJ95	Arabidopsis thaliana	27%	97%
Q9KL62	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	30%	100%
Q9L233	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	30%	100%
Q9P4C2	Kluyveromyces marxianus	28%	100%
Q9P6C8	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	28%	100%
Q9QYY9	Mus musculus	25%	93%
Q9RTU4	Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)	30%	100%
Q9SJ10	Arabidopsis thaliana	50%	94%
Q9SJ25	Arabidopsis thaliana	50%	94%
Q9SK86	Arabidopsis thaliana	25%	91%
Q9SK87	Arabidopsis thaliana	24%	91%
Q9UYX0	Pyrococcus abyssi (strain GE5 / Orsay)	27%	100%
Q9WYP3	Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)	26%	89%
Q9Z2M2	Geomys attwateri	27%	94%
Q9Z9U1	Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)	25%	100%
Q9ZRF1	Fragaria ananassa	53%	98%
W8JCF0	Catharanthus roseus	42%	97%
W8JDE0	Catharanthus roseus	48%	98%
W8JWW7	Catharanthus roseus	41%	97%