| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | yes | yes: 18 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 9, no: 20 |
| NetGPI | no | yes: 0, no: 29 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005774 | vacuolar membrane | 5 | 30 |
| GO:0016020 | membrane | 2 | 30 |
| GO:0031090 | organelle membrane | 3 | 30 |
| GO:0032991 | protein-containing complex | 1 | 30 |
| GO:0033177 | proton-transporting two-sector ATPase complex, proton-transporting domain | 3 | 30 |
| GO:0033179 | proton-transporting V-type ATPase, V0 domain | 4 | 30 |
| GO:0098588 | bounding membrane of organelle | 4 | 30 |
| GO:0098796 | membrane protein complex | 2 | 30 |
| GO:0110165 | cellular anatomical entity | 1 | 30 |
Related structures:
AlphaFold database: A4I051
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0003824 | catalytic activity | 1 | 19 |
| GO:0005215 | transporter activity | 1 | 30 |
| GO:0008324 | monoatomic cation transmembrane transporter activity | 4 | 30 |
| GO:0009678 | pyrophosphate hydrolysis-driven proton transmembrane transporter activity | 5 | 30 |
| GO:0015075 | monoatomic ion transmembrane transporter activity | 3 | 30 |
| GO:0015078 | proton transmembrane transporter activity | 5 | 30 |
| GO:0015318 | inorganic molecular entity transmembrane transporter activity | 3 | 30 |
| GO:0015399 | primary active transmembrane transporter activity | 4 | 30 |
| GO:0016787 | hydrolase activity | 2 | 19 |
| GO:0019829 | ATPase-coupled monoatomic cation transmembrane transporter activity | 3 | 30 |
| GO:0022804 | active transmembrane transporter activity | 3 | 30 |
| GO:0022853 | active monoatomic ion transmembrane transporter activity | 4 | 30 |
| GO:0022857 | transmembrane transporter activity | 2 | 30 |
| GO:0022890 | inorganic cation transmembrane transporter activity | 4 | 30 |
| GO:0042625 | ATPase-coupled ion transmembrane transporter activity | 3 | 30 |
| GO:0042626 | ATPase-coupled transmembrane transporter activity | 2 | 30 |
| GO:0044769 | ATPase activity, coupled to transmembrane movement of ions, rotational mechanism | 4 | 30 |
| GO:0046961 | proton-transporting ATPase activity, rotational mechanism | 4 | 30 |
| GO:0140657 | ATP-dependent activity | 1 | 30 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| DOC_MAPK_DCC_7 | 127 | 135 | PF00069 | 0.431 |
| DOC_MAPK_DCC_7 | 51 | 61 | PF00069 | 0.434 |
| DOC_MAPK_gen_1 | 124 | 134 | PF00069 | 0.435 |
| DOC_MAPK_gen_1 | 51 | 59 | PF00069 | 0.434 |
| DOC_MAPK_MEF2A_6 | 124 | 132 | PF00069 | 0.437 |
| DOC_MAPK_MEF2A_6 | 54 | 61 | PF00069 | 0.434 |
| DOC_USP7_MATH_1 | 160 | 164 | PF00917 | 0.259 |
| LIG_APCC_ABBA_1 | 135 | 140 | PF00400 | 0.277 |
| LIG_BIR_II_1 | 1 | 5 | PF00653 | 0.404 |
| LIG_FHA_1 | 123 | 129 | PF00498 | 0.447 |
| LIG_FHA_1 | 147 | 153 | PF00498 | 0.387 |
| LIG_LIR_Gen_1 | 89 | 99 | PF02991 | 0.230 |
| LIG_LIR_Nem_3 | 83 | 88 | PF02991 | 0.301 |
| LIG_LIR_Nem_3 | 89 | 94 | PF02991 | 0.264 |
| LIG_SH2_CRK | 68 | 72 | PF00017 | 0.277 |
| LIG_SH2_SRC | 109 | 112 | PF00017 | 0.274 |
| LIG_SH2_SRC | 120 | 123 | PF00017 | 0.431 |
| LIG_SH3_3 | 3 | 9 | PF00018 | 0.441 |
| LIG_UBA3_1 | 147 | 156 | PF00899 | 0.387 |
| MOD_CAAXbox | 164 | 167 | PF01239 | 0.419 |
| MOD_GlcNHglycan | 158 | 161 | PF01048 | 0.470 |
| MOD_GlcNHglycan | 82 | 85 | PF01048 | 0.500 |
| MOD_GlcNHglycan | 88 | 91 | PF01048 | 0.455 |
| MOD_GSK3_1 | 151 | 158 | PF00069 | 0.435 |
| MOD_GSK3_1 | 160 | 167 | PF00069 | 0.384 |
| MOD_NEK2_1 | 1 | 6 | PF00069 | 0.425 |
| MOD_NEK2_1 | 151 | 156 | PF00069 | 0.416 |
| MOD_NEK2_1 | 70 | 75 | PF00069 | 0.313 |
| MOD_NEK2_1 | 80 | 85 | PF00069 | 0.284 |
| MOD_Plk_4 | 70 | 76 | PF00069 | 0.312 |
| MOD_SUMO_for_1 | 123 | 126 | PF00179 | 0.449 |
| TRG_ENDOCYTIC_2 | 68 | 71 | PF00928 | 0.282 |
| TRG_ENDOCYTIC_2 | 85 | 88 | PF00928 | 0.284 |
| TRG_ENDOCYTIC_2 | 91 | 94 | PF00928 | 0.271 |
| TRG_NES_CRM1_1 | 126 | 140 | PF08389 | 0.449 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N0P3G9 | Leptomonas seymouri | 30% | 75% |
| A0A0N0P7K0 | Leptomonas seymouri | 60% | 85% |
| A0A0N1HSG6 | Leptomonas seymouri | 66% | 88% |
| A0A0N1I3H6 | Leptomonas seymouri | 90% | 100% |
| A0A0S4IU71 | Bodo saltans | 63% | 97% |
| A0A0S4JFM4 | Bodo saltans | 79% | 94% |
| A0A0S4KKA5 | Bodo saltans | 66% | 86% |
| A0A1X0NGC8 | Trypanosomatidae | 85% | 100% |
| A0A1X0NHL5 | Trypanosomatidae | 64% | 87% |
| A0A1X0NZ73 | Trypanosomatidae | 60% | 92% |
| A0A1X0P179 | Trypanosomatidae | 30% | 75% |
| A0A3Q8II19 | Leishmania donovani | 58% | 83% |
| A0A3Q8II88 | Leishmania donovani | 31% | 75% |
| A0A3Q8ILV9 | Leishmania donovani | 100% | 100% |
| A0A3R7MQK8 | Trypanosoma rangeli | 27% | 75% |
| A0A3R7RFU6 | Trypanosoma rangeli | 64% | 86% |
| A0A3S7WX01 | Leishmania donovani | 64% | 89% |
| A0A422N304 | Trypanosoma rangeli | 57% | 84% |
| A0A422NW00 | Trypanosoma rangeli | 85% | 100% |
| A2ZBW5 | Oryza sativa subsp. indica | 57% | 100% |
| A4HCM7 | Leishmania braziliensis | 93% | 100% |
| A4HGG2 | Leishmania braziliensis | 59% | 100% |
| A4HIV2 | Leishmania braziliensis | 30% | 100% |
| A4HLC1 | Leishmania braziliensis | 64% | 100% |
| A4HZI5 | Leishmania infantum | 64% | 100% |
| A4I3J4 | Leishmania infantum | 58% | 83% |
| A4I657 | Leishmania infantum | 31% | 75% |
| C0HLB3 | Caenorhabditis elegans | 46% | 100% |
| C0HLB4 | Caenorhabditis elegans | 46% | 100% |
| C0HLB5 | Caenorhabditis briggsae | 46% | 100% |
| C0HLB6 | Caenorhabditis briggsae | 46% | 100% |
| C9ZRH7 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 29% | 75% |
| D0A0Y8 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 68% | 87% |
| D0A7U7 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 59% | 66% |
| E9AVH5 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 65% | 100% |
| E9AW14 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 98% | 100% |
| E9AZT4 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 58% | 100% |
| E9B1E0 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 32% | 100% |
| G5EDB8 | Caenorhabditis elegans | 30% | 78% |
| O14046 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 26% | 84% |
| O16110 | Aedes aegypti | 51% | 100% |
| O18882 | Ovis aries | 48% | 100% |
| O22552 | Vigna radiata var. radiata | 57% | 100% |
| O24011 | Solanum lycopersicum | 57% | 100% |
| P0DH92 | Arabidopsis thaliana | 56% | 100% |
| P0DH93 | Arabidopsis thaliana | 56% | 100% |
| P0DH94 | Arabidopsis thaliana | 56% | 100% |
| P23380 | Drosophila melanogaster | 50% | 100% |
| P23956 | Bos taurus | 48% | 100% |
| P23957 | Avena sativa | 57% | 100% |
| P23968 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 30% | 78% |
| P25515 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 47% | 100% |
| P27449 | Homo sapiens | 47% | 100% |
| P31403 | Manduca sexta | 48% | 100% |
| P31413 | Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) | 52% | 100% |
| P32842 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 46% | 100% |
| P50515 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 52% | 100% |
| P54642 | Dictyostelium discoideum | 44% | 85% |
| P55277 | Heliothis virescens | 48% | 100% |
| P59228 | Arabidopsis thaliana | 56% | 100% |
| P59229 | Arabidopsis thaliana | 57% | 100% |
| P63081 | Rattus norvegicus | 49% | 100% |
| P63082 | Mus musculus | 49% | 100% |
| P68161 | Mesembryanthemum crystallinum | 55% | 100% |
| P68162 | Beta vulgaris | 55% | 100% |
| Q00607 | Candida tropicalis | 45% | 100% |
| Q03105 | Torpedo marmorata | 48% | 100% |
| Q0IUB5 | Oryza sativa subsp. japonica | 57% | 100% |
| Q17046 | Ascaris suum | 46% | 100% |
| Q21898 | Caenorhabditis elegans | 45% | 99% |
| Q24808 | Entamoeba dispar | 42% | 95% |
| Q24810 | Entamoeba histolytica | 42% | 94% |
| Q26250 | Nephrops norvegicus | 48% | 100% |
| Q2TA24 | Bos taurus | 30% | 81% |
| Q40585 | Nicotiana tabacum | 56% | 100% |
| Q43362 | Chrysotila carterae | 54% | 100% |
| Q43434 | Gossypium hirsutum | 57% | 100% |
| Q4Q6S2 | Leishmania major | 33% | 100% |
| Q4Q8F0 | Leishmania major | 59% | 100% |
| Q4QBG2 | Leishmania major | 98% | 100% |
| Q4QC03 | Leishmania major | 64% | 100% |
| Q6BSB9 | Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) | 46% | 100% |
| Q6CT28 | Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) | 45% | 100% |
| Q6FUY5 | Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) | 47% | 100% |
| Q755G4 | Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) | 45% | 100% |
| Q91V37 | Mus musculus | 30% | 81% |
| Q96473 | Kalanchoe daigremontiana | 57% | 100% |
| Q99437 | Homo sapiens | 30% | 81% |
| Q9SLA2 | Arabidopsis thaliana | 32% | 94% |
| Q9SZY7 | Arabidopsis thaliana | 32% | 93% |
| Q9URZ8 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 46% | 100% |
| Q9Y874 | Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) | 43% | 100% |