Dynactin domain-containing protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I036_LEIIN

TriTrypDb:

LINF_220019400

Length:

353

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized (Fragment)

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I036

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I036

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1	5	PF00656	0.465
CLV_C14_Caspase3-7	137	141	PF00656	0.589
CLV_C14_Caspase3-7	213	217	PF00656	0.640
CLV_C14_Caspase3-7	228	232	PF00656	0.545
CLV_C14_Caspase3-7	46	50	PF00656	0.589
CLV_NRD_NRD_1	210	212	PF00675	0.622
CLV_NRD_NRD_1	260	262	PF00675	0.461
CLV_NRD_NRD_1	41	43	PF00675	0.472
CLV_NRD_NRD_1	59	61	PF00675	0.586
CLV_PCSK_KEX2_1	260	262	PF00082	0.403
CLV_PCSK_KEX2_1	41	43	PF00082	0.472
CLV_PCSK_KEX2_1	59	61	PF00082	0.586
CLV_PCSK_SKI1_1	196	200	PF00082	0.477
CLV_PCSK_SKI1_1	246	250	PF00082	0.546
CLV_PCSK_SKI1_1	314	318	PF00082	0.441
DEG_APCC_DBOX_1	195	203	PF00400	0.485
DEG_Nend_UBRbox_2	1	2	PF02207	0.571
DOC_CYCLIN_RxL_1	193	201	PF00134	0.474
DOC_MAPK_gen_1	185	194	PF00069	0.456
DOC_USP7_MATH_1	19	23	PF00917	0.375
DOC_USP7_MATH_1	287	291	PF00917	0.452
DOC_USP7_MATH_1	301	305	PF00917	0.476
DOC_USP7_MATH_1	58	62	PF00917	0.456
DOC_USP7_MATH_1	92	96	PF00917	0.442
DOC_WW_Pin1_4	347	352	PF00397	0.592
LIG_14-3-3_CanoR_1	159	167	PF00244	0.438
LIG_14-3-3_CanoR_1	224	234	PF00244	0.563
LIG_14-3-3_CanoR_1	59	63	PF00244	0.435
LIG_APCC_ABBA_1	192	197	PF00400	0.468
LIG_FHA_1	1	7	PF00498	0.450
LIG_FHA_1	142	148	PF00498	0.510
LIG_FHA_1	225	231	PF00498	0.690
LIG_FHA_1	92	98	PF00498	0.478
LIG_FHA_2	150	156	PF00498	0.432
LIG_GBD_Chelix_1	241	249	PF00786	0.455
LIG_LIR_Apic_2	338	343	PF02991	0.599
LIG_LIR_Nem_3	193	198	PF02991	0.567
LIG_NRBOX	11	17	PF00104	0.456
LIG_SH2_CRK	340	344	PF00017	0.603
LIG_SH2_NCK_1	239	243	PF00017	0.468
LIG_SH2_STAP1	125	129	PF00017	0.630
LIG_SH2_STAP1	154	158	PF00017	0.429
LIG_SH2_STAP1	308	312	PF00017	0.468
LIG_SH2_STAP1	65	69	PF00017	0.437
LIG_SH2_STAT3	308	311	PF00017	0.470
LIG_SUMO_SIM_par_1	81	89	PF11976	0.435
LIG_TRAF2_1	32	35	PF00917	0.466
MOD_CK1_1	225	231	PF00069	0.681
MOD_CK1_1	344	350	PF00069	0.702
MOD_CK1_1	95	101	PF00069	0.446
MOD_CK2_1	149	155	PF00069	0.514
MOD_CK2_1	19	25	PF00069	0.549
MOD_CK2_1	287	293	PF00069	0.453
MOD_GlcNHglycan	179	182	PF01048	0.562
MOD_GlcNHglycan	213	216	PF01048	0.642
MOD_GlcNHglycan	227	230	PF01048	0.640
MOD_GlcNHglycan	234	237	PF01048	0.593
MOD_GlcNHglycan	52	55	PF01048	0.545
MOD_GSK3_1	341	348	PF00069	0.584
MOD_GSK3_1	91	98	PF00069	0.444
MOD_NEK2_1	139	144	PF00069	0.592
MOD_NEK2_1	147	152	PF00069	0.419
MOD_PIKK_1	147	153	PF00454	0.602
MOD_PIKK_1	158	164	PF00454	0.427
MOD_PIKK_1	301	307	PF00454	0.476
MOD_PKA_1	211	217	PF00069	0.636
MOD_PKA_2	158	164	PF00069	0.435
MOD_PKA_2	19	25	PF00069	0.377
MOD_PKA_2	223	229	PF00069	0.689
MOD_PKA_2	58	64	PF00069	0.401
MOD_Plk_1	132	138	PF00069	0.453
MOD_Plk_1	314	320	PF00069	0.506
MOD_Plk_4	149	155	PF00069	0.435
MOD_Plk_4	198	204	PF00069	0.493
MOD_Plk_4	314	320	PF00069	0.487
MOD_Plk_4	92	98	PF00069	0.443
MOD_ProDKin_1	347	353	PF00069	0.598
MOD_SUMO_rev_2	323	332	PF00179	0.543
TRG_DiLeu_BaEn_1	11	16	PF01217	0.399
TRG_DiLeu_BaEn_4	88	94	PF01217	0.441
TRG_ER_diArg_1	259	261	PF00400	0.465
TRG_ER_diArg_1	297	300	PF00400	0.560
TRG_ER_diArg_1	40	42	PF00400	0.474
TRG_NES_CRM1_1	127	140	PF08389	0.453
TRG_NES_CRM1_1	7	21	PF08389	0.411
TRG_NES_CRM1_1	74	89	PF08389	0.434
TRG_Pf-PMV_PEXEL_1	24	28	PF00026	0.390
TRG_Pf-PMV_PEXEL_1	289	293	PF00026	0.567

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IGH1	Leptomonas seymouri	28%	96%