Putative centrin

Quick info Annotations Localization Phosphorylation Abundance Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Putative centrin

Gene product:

centrin-4 - putative

Species:

Leishmania infantum

UniProt:

A4I000_LEIIN

TriTrypDb:

LINF_220020200

Length:

149

Annotations

Annotations by Jardim et al.

Metal Binding, centrin

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	yes	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 16

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 21

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Show entries

Cellular components
Term	Name	Level	Count
GO:0005813	centrosome	3	1
GO:0005814	centriole	5	1
GO:0005815	microtubule organizing center	2	2
GO:0036064	ciliary basal body	3	1
GO:0043226	organelle	2	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	2

Previous1Next

Phosphorylation

Amastigote: 99

Abundance

Amastigote (protein)


Source	Evidence on protein	Close homologs
Pescher et al. (upgregulation)	no	yes: 0

Promastigote and amastigote


Source	Evidence on protein	Close homologs
Lahav et al. - mRNA - Protein

Expansion

Sequence features

A4I000

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I000

Function

Show entries

Biological processes
Term	Name	Level	Count
GO:0000278	mitotic cell cycle	3	1
GO:0006996	organelle organization	4	1
GO:0007017	microtubule-based process	2	1
GO:0007049	cell cycle	2	1
GO:0007099	centriole replication	3	1
GO:0009987	cellular process	1	1
GO:0010564	regulation of cell cycle process	5	1
GO:0016043	cellular component organization	3	1
GO:0022402	cell cycle process	2	1
GO:0022607	cellular component assembly	4	1

Previous1 2 3Next

Show entries

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	12
GO:0005509	calcium ion binding	5	12
GO:0043167	ion binding	2	12
GO:0043169	cation binding	3	12
GO:0046872	metal ion binding	4	12

Previous1Next

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	128	132	PF00656	0.323
CLV_PCSK_SKI1_1	10	14	PF00082	0.291
DOC_CYCLIN_RxL_1	31	42	PF00134	0.292
DOC_MAPK_gen_1	94	100	PF00069	0.305
DOC_PP1_RVXF_1	32	39	PF00149	0.291
DOC_PP1_RVXF_1	95	101	PF00149	0.291
DOC_USP7_MATH_1	18	22	PF00917	0.307
DOC_USP7_UBL2_3	104	108	PF12436	0.302
DOC_WW_Pin1_4	76	81	PF00397	0.443
LIG_14-3-3_CanoR_1	48	54	PF00244	0.298

Previous1 2 3 4Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P206	Leptomonas seymouri	41%	100%
A0A0N0P419	Leptomonas seymouri	32%	85%
A0A0N0P4B4	Leptomonas seymouri	27%	100%
A0A0N0P7N1	Leptomonas seymouri	34%	71%
A0A0N0P8Y6	Leptomonas seymouri	44%	82%
A0A0N1I2Q3	Leptomonas seymouri	95%	100%
A0A0N1IMR9	Leptomonas seymouri	33%	90%
A0A0N1PB14	Leptomonas seymouri	43%	71%
A0A0N1PB23	Leptomonas seymouri	35%	96%
A0A0S4ILD1	Bodo saltans	39%	85%

Previous1 2 3 4 5…47Next