AIG1-type G domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HZZ8_LEIIN

TriTrypDb:

LINF_220019300

Length:

591

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HZZ8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HZZ8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	272	276	PF00656	0.428
CLV_C14_Caspase3-7	90	94	PF00656	0.329
CLV_NRD_NRD_1	104	106	PF00675	0.312
CLV_NRD_NRD_1	119	121	PF00675	0.427
CLV_NRD_NRD_1	201	203	PF00675	0.320
CLV_NRD_NRD_1	244	246	PF00675	0.327
CLV_NRD_NRD_1	258	260	PF00675	0.349
CLV_NRD_NRD_1	323	325	PF00675	0.313
CLV_NRD_NRD_1	49	51	PF00675	0.314
CLV_PCSK_KEX2_1	104	106	PF00082	0.312
CLV_PCSK_KEX2_1	119	121	PF00082	0.427
CLV_PCSK_KEX2_1	201	203	PF00082	0.320
CLV_PCSK_KEX2_1	222	224	PF00082	0.375
CLV_PCSK_KEX2_1	234	236	PF00082	0.327
CLV_PCSK_KEX2_1	244	246	PF00082	0.327
CLV_PCSK_KEX2_1	257	259	PF00082	0.348
CLV_PCSK_KEX2_1	323	325	PF00082	0.313
CLV_PCSK_KEX2_1	487	489	PF00082	0.348
CLV_PCSK_KEX2_1	49	51	PF00082	0.314
CLV_PCSK_PC1ET2_1	222	224	PF00082	0.375
CLV_PCSK_PC1ET2_1	234	236	PF00082	0.327
CLV_PCSK_PC1ET2_1	487	489	PF00082	0.348
CLV_PCSK_PC7_1	218	224	PF00082	0.370
CLV_PCSK_SKI1_1	154	158	PF00082	0.298
CLV_PCSK_SKI1_1	323	327	PF00082	0.311
CLV_PCSK_SKI1_1	413	417	PF00082	0.344
CLV_PCSK_SKI1_1	490	494	PF00082	0.351
CLV_PCSK_SKI1_1	5	9	PF00082	0.345
CLV_PCSK_SKI1_1	50	54	PF00082	0.303
CLV_PCSK_SKI1_1	505	509	PF00082	0.329
CLV_PCSK_SKI1_1	537	541	PF00082	0.338
CLV_PCSK_SKI1_1	79	83	PF00082	0.316
DEG_APCC_DBOX_1	479	487	PF00400	0.371
DEG_APCC_DBOX_1	504	512	PF00400	0.330
DEG_APCC_DBOX_1	536	544	PF00400	0.335
DEG_APCC_DBOX_1	78	86	PF00400	0.316
DEG_Kelch_Keap1_1	563	568	PF01344	0.504
DEG_Nend_UBRbox_2	1	3	PF02207	0.368
DOC_CYCLIN_RxL_1	2	9	PF00134	0.349
DOC_MAPK_gen_1	257	264	PF00069	0.349
DOC_MAPK_gen_1	500	510	PF00069	0.329
DOC_MAPK_MEF2A_6	290	297	PF00069	0.442
DOC_MIT_MIM_1	241	249	PF04212	0.322
DOC_USP7_MATH_1	15	19	PF00917	0.315
DOC_USP7_MATH_1	159	163	PF00917	0.282
DOC_USP7_MATH_1	386	390	PF00917	0.332
DOC_USP7_MATH_1	562	566	PF00917	0.499
DOC_USP7_MATH_2	138	144	PF00917	0.338
DOC_USP7_UBL2_3	88	92	PF12436	0.328
DOC_WW_Pin1_4	426	431	PF00397	0.473
LIG_Actin_WH2_2	335	351	PF00022	0.300
LIG_Actin_WH2_2	511	529	PF00022	0.333
LIG_BIR_III_4	282	286	PF00653	0.474
LIG_BRCT_BRCA1_1	583	587	PF00533	0.447
LIG_Clathr_ClatBox_1	64	68	PF01394	0.309
LIG_EH1_1	176	184	PF00400	0.326
LIG_FHA_1	183	189	PF00498	0.300
LIG_FHA_1	209	215	PF00498	0.310
LIG_FHA_1	31	37	PF00498	0.303
LIG_FHA_1	335	341	PF00498	0.293
LIG_FHA_1	361	367	PF00498	0.318
LIG_FHA_1	551	557	PF00498	0.414
LIG_FHA_1	98	104	PF00498	0.323
LIG_FHA_2	166	172	PF00498	0.323
LIG_FHA_2	193	199	PF00498	0.359
LIG_FHA_2	310	316	PF00498	0.343
LIG_FHA_2	356	362	PF00498	0.329
LIG_FHA_2	468	474	PF00498	0.468
LIG_Integrin_RGD_1	169	171	PF01839	0.335
LIG_LIR_Apic_2	205	209	PF02991	0.320
LIG_LIR_Gen_1	140	150	PF02991	0.331
LIG_LIR_Gen_1	370	379	PF02991	0.313
LIG_LIR_LC3C_4	337	342	PF02991	0.290
LIG_LIR_Nem_3	140	145	PF02991	0.332
LIG_LIR_Nem_3	333	339	PF02991	0.294
LIG_LIR_Nem_3	370	375	PF02991	0.315
LIG_LIR_Nem_3	584	590	PF02991	0.442
LIG_SH2_CRK	206	210	PF00017	0.316
LIG_SH2_SRC	206	209	PF00017	0.314
LIG_SH2_STAP1	344	348	PF00017	0.309
LIG_SH2_STAP1	404	408	PF00017	0.316
LIG_SH3_3	132	138	PF00018	0.318
LIG_SUMO_SIM_anti_2	305	316	PF11976	0.362
LIG_SUMO_SIM_anti_2	337	343	PF11976	0.288
LIG_SUMO_SIM_anti_2	506	513	PF11976	0.326
LIG_SUMO_SIM_par_1	127	134	PF11976	0.348
LIG_SUMO_SIM_par_1	305	316	PF11976	0.362
LIG_SUMO_SIM_par_1	337	343	PF11976	0.288
LIG_SUMO_SIM_par_1	539	545	PF11976	0.338
LIG_SUMO_SIM_par_1	63	69	PF11976	0.307
LIG_TRAF2_1	106	109	PF00917	0.322
LIG_TRAF2_1	312	315	PF00917	0.330
LIG_TRAF2_1	343	346	PF00917	0.298
LIG_TRAF2_1	548	551	PF00917	0.350
LIG_UBA3_1	493	500	PF00899	0.343
MOD_CK1_1	313	319	PF00069	0.328
MOD_CK2_1	192	198	PF00069	0.371
MOD_CK2_1	309	315	PF00069	0.354
MOD_CK2_1	340	346	PF00069	0.295
MOD_CK2_1	355	361	PF00069	0.332
MOD_CK2_1	447	453	PF00069	0.512
MOD_CK2_1	471	477	PF00069	0.429
MOD_CK2_1	562	568	PF00069	0.501
MOD_CK2_1	66	72	PF00069	0.312
MOD_GlcNHglycan	122	125	PF01048	0.420
MOD_GlcNHglycan	250	256	PF01048	0.319
MOD_GlcNHglycan	426	429	PF01048	0.463
MOD_GlcNHglycan	436	441	PF01048	0.503
MOD_GlcNHglycan	531	534	PF01048	0.331
MOD_GlcNHglycan	565	568	PF01048	0.502
MOD_GlcNHglycan	575	578	PF01048	0.477
MOD_GlcNHglycan	583	586	PF01048	0.444
MOD_GlcNHglycan	8	11	PF01048	0.321
MOD_GlcNHglycan	89	92	PF01048	0.327
MOD_GSK3_1	178	185	PF00069	0.328
MOD_GSK3_1	269	276	PF00069	0.414
MOD_GSK3_1	309	316	PF00069	0.351
MOD_GSK3_1	330	337	PF00069	0.295
MOD_GSK3_1	356	363	PF00069	0.328
MOD_GSK3_1	424	431	PF00069	0.463
MOD_GSK3_1	443	450	PF00069	0.509
MOD_GSK3_1	461	468	PF00069	0.519
MOD_GSK3_1	563	570	PF00069	0.502
MOD_N-GLC_1	562	567	PF02516	0.499
MOD_NEK2_1	182	187	PF00069	0.298
MOD_NEK2_1	332	337	PF00069	0.296
MOD_NEK2_2	128	133	PF00069	0.337
MOD_PIKK_1	313	319	PF00454	0.328
MOD_PIKK_1	461	467	PF00454	0.525
MOD_PIKK_1	513	519	PF00454	0.319
MOD_PK_1	269	275	PF00069	0.411
MOD_PK_1	443	449	PF00069	0.510
MOD_PK_1	71	77	PF00069	0.316
MOD_PKA_1	120	126	PF00069	0.418
MOD_PKA_1	234	240	PF00069	0.316
MOD_PKA_2	234	240	PF00069	0.316
MOD_PKA_2	424	430	PF00069	0.459
MOD_PKA_2	442	448	PF00069	0.510
MOD_PKA_2	471	477	PF00069	0.429
MOD_PKA_2	563	569	PF00069	0.503
MOD_PKA_2	573	579	PF00069	0.483
MOD_Plk_1	140	146	PF00069	0.332
MOD_Plk_1	192	198	PF00069	0.371
MOD_Plk_1	355	361	PF00069	0.332
MOD_Plk_1	447	453	PF00069	0.512
MOD_Plk_1	520	526	PF00069	0.343
MOD_Plk_1	71	77	PF00069	0.316
MOD_Plk_2-3	356	362	PF00069	0.329
MOD_Plk_2-3	449	455	PF00069	0.513
MOD_Plk_2-3	66	72	PF00069	0.312
MOD_Plk_4	178	184	PF00069	0.329
MOD_Plk_4	192	198	PF00069	0.371
MOD_Plk_4	71	77	PF00069	0.316
MOD_ProDKin_1	426	432	PF00069	0.478
MOD_SUMO_for_1	486	489	PF00179	0.351
MOD_SUMO_rev_2	495	502	PF00179	0.333
TRG_DiLeu_BaEn_1	20	25	PF01217	0.317
TRG_DiLeu_BaEn_1	305	310	PF01217	0.389
TRG_DiLeu_BaEn_1	371	376	PF01217	0.314
TRG_DiLeu_BaEn_1	489	494	PF01217	0.349
TRG_DiLeu_BaEn_4	108	114	PF01217	0.354
TRG_DiLeu_BaEn_4	327	333	PF01217	0.295
TRG_DiLeu_LyEn_5	20	25	PF01217	0.317
TRG_ER_diArg_1	103	105	PF00400	0.321
TRG_ER_diArg_1	201	203	PF00400	0.320
TRG_ER_diArg_1	215	218	PF00400	0.347
TRG_ER_diArg_1	244	246	PF00400	0.327
TRG_ER_diArg_1	257	259	PF00400	0.348
TRG_ER_diArg_1	322	324	PF00400	0.320
TRG_ER_diArg_1	48	50	PF00400	0.315
TRG_NES_CRM1_1	364	377	PF08389	0.313
TRG_NES_CRM1_1	513	528	PF08389	0.334
TRG_NLS_Bipartite_1	104	124	PF00514	0.375
TRG_NLS_MonoExtN_4	119	124	PF00514	0.420
TRG_Pf-PMV_PEXEL_1	201	205	PF00026	0.332
TRG_Pf-PMV_PEXEL_1	23	28	PF00026	0.315
TRG_Pf-PMV_PEXEL_1	244	248	PF00026	0.324
TRG_Pf-PMV_PEXEL_1	324	328	PF00026	0.309
TRG_Pf-PMV_PEXEL_1	398	402	PF00026	0.327
TRG_Pf-PMV_PEXEL_1	537	542	PF00026	0.338

Homologs


Protein	Taxonomy	Sequence identity	Coverage
C9ZN16	TRYB9	34%	34%
Q585H6	TRYB2	34%	35%