Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HZQ1_LEIIN

TriTrypDb:

LINF_220007300

Length:

329

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HZQ1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HZQ1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	29	33	PF00656	0.631
CLV_NRD_NRD_1	61	63	PF00675	0.618
CLV_PCSK_KEX2_1	53	55	PF00082	0.754
CLV_PCSK_PC1ET2_1	53	55	PF00082	0.781
CLV_PCSK_SKI1_1	309	313	PF00082	0.805
CLV_PCSK_SKI1_1	63	67	PF00082	0.724
DOC_ANK_TNKS_1	243	250	PF00023	0.778
DOC_CYCLIN_RxL_1	303	316	PF00134	0.800
DOC_CYCLIN_yCln2_LP_2	97	103	PF00134	0.738
DOC_PP1_RVXF_1	307	314	PF00149	0.801
DOC_USP7_MATH_1	108	112	PF00917	0.735
DOC_USP7_MATH_1	150	154	PF00917	0.627
DOC_USP7_MATH_1	231	235	PF00917	0.838
DOC_USP7_MATH_1	31	35	PF00917	0.726
DOC_USP7_MATH_1	319	323	PF00917	0.623
DOC_USP7_MATH_1	85	89	PF00917	0.749
DOC_USP7_UBL2_3	305	309	PF12436	0.699
DOC_USP7_UBL2_3	59	63	PF12436	0.724
DOC_WW_Pin1_4	148	153	PF00397	0.656
DOC_WW_Pin1_4	174	179	PF00397	0.762
DOC_WW_Pin1_4	203	208	PF00397	0.808
DOC_WW_Pin1_4	211	216	PF00397	0.692
DOC_WW_Pin1_4	268	273	PF00397	0.763
DOC_WW_Pin1_4	289	294	PF00397	0.786
DOC_WW_Pin1_4	324	329	PF00397	0.661
DOC_WW_Pin1_4	46	51	PF00397	0.772
DOC_WW_Pin1_4	96	101	PF00397	0.732
LIG_14-3-3_CanoR_1	286	294	PF00244	0.800
LIG_14-3-3_CanoR_1	86	92	PF00244	0.809
LIG_BIR_II_1	1	5	PF00653	0.753
LIG_BIR_III_2	316	320	PF00653	0.818
LIG_FHA_1	116	122	PF00498	0.729
LIG_FHA_1	149	155	PF00498	0.824
LIG_FHA_1	259	265	PF00498	0.745
LIG_FHA_1	68	74	PF00498	0.734
LIG_FHA_1	88	94	PF00498	0.536
LIG_FHA_2	132	138	PF00498	0.657
LIG_FHA_2	170	176	PF00498	0.723
LIG_FHA_2	253	259	PF00498	0.791
LIG_FHA_2	27	33	PF00498	0.682
LIG_FHA_2	310	316	PF00498	0.706
LIG_PAM2_1	46	58	PF00658	0.569
LIG_SH2_STAT5	171	174	PF00017	0.622
LIG_SH3_3	175	181	PF00018	0.683
LIG_SH3_3	201	207	PF00018	0.764
LIG_SH3_3	8	14	PF00018	0.824
LIG_Sin3_3	101	108	PF02671	0.609
LIG_SUMO_SIM_par_1	70	78	PF11976	0.700
LIG_SUMO_SIM_par_1	88	96	PF11976	0.597
LIG_TRAF2_1	5	8	PF00917	0.769
MOD_CDK_SPxxK_3	46	53	PF00069	0.773
MOD_CK1_1	115	121	PF00069	0.786
MOD_CK1_1	129	135	PF00069	0.567
MOD_CK1_1	2	8	PF00069	0.746
MOD_CK1_1	206	212	PF00069	0.762
MOD_CK1_1	227	233	PF00069	0.784
MOD_CK1_1	252	258	PF00069	0.687
MOD_CK1_1	285	291	PF00069	0.801
MOD_CK1_1	35	41	PF00069	0.753
MOD_CK2_1	150	156	PF00069	0.827
MOD_CK2_1	169	175	PF00069	0.511
MOD_CK2_1	194	200	PF00069	0.699
MOD_CK2_1	2	8	PF00069	0.706
MOD_CK2_1	250	256	PF00069	0.825
MOD_GlcNHglycan	1	4	PF01048	0.770
MOD_GlcNHglycan	113	117	PF01048	0.716
MOD_GlcNHglycan	208	211	PF01048	0.766
MOD_GlcNHglycan	226	229	PF01048	0.535
MOD_GlcNHglycan	233	236	PF01048	0.682
MOD_GlcNHglycan	240	243	PF01048	0.585
MOD_GlcNHglycan	252	255	PF01048	0.646
MOD_GlcNHglycan	82	85	PF01048	0.740
MOD_GlcNHglycan	87	90	PF01048	0.755
MOD_GSK3_1	108	115	PF00069	0.726
MOD_GSK3_1	227	234	PF00069	0.787
MOD_GSK3_1	250	257	PF00069	0.753
MOD_GSK3_1	264	271	PF00069	0.690
MOD_GSK3_1	285	292	PF00069	0.801
MOD_GSK3_1	31	38	PF00069	0.786
MOD_GSK3_1	319	326	PF00069	0.782
MOD_GSK3_1	63	70	PF00069	0.721
MOD_N-GLC_2	279	281	PF02516	0.716
MOD_NEK2_1	323	328	PF00069	0.768
MOD_PIKK_1	15	21	PF00454	0.759
MOD_PIKK_1	216	222	PF00454	0.826
MOD_PKA_2	285	291	PF00069	0.814
MOD_PKA_2	85	91	PF00069	0.810
MOD_Plk_1	129	135	PF00069	0.766
MOD_Plk_1	31	37	PF00069	0.790
MOD_Plk_1	67	73	PF00069	0.631
MOD_Plk_2-3	68	74	PF00069	0.590
MOD_Plk_4	68	74	PF00069	0.590
MOD_ProDKin_1	148	154	PF00069	0.657
MOD_ProDKin_1	174	180	PF00069	0.764
MOD_ProDKin_1	203	209	PF00069	0.811
MOD_ProDKin_1	211	217	PF00069	0.692
MOD_ProDKin_1	268	274	PF00069	0.759
MOD_ProDKin_1	289	295	PF00069	0.787
MOD_ProDKin_1	46	52	PF00069	0.772
MOD_ProDKin_1	96	102	PF00069	0.736
MOD_SUMO_rev_2	219	226	PF00179	0.728
TRG_DiLeu_BaEn_1	8	13	PF01217	0.723
TRG_NLS_MonoExtC_3	52	58	PF00514	0.676
TRG_NLS_MonoExtN_4	50	57	PF00514	0.674

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H7A5	Leishmania donovani	99%	100%
A4HC74	Leishmania braziliensis	53%	100%
E9AVK7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	80%	100%
Q4QBX2	Leishmania major	82%	100%