Putative amino acid permease

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

amino acid permease - putative

Species:

Leishmania infantum

UniProt:

A4HZQ0_LEIIN

TriTrypDb:

LINF_220007200

Length:

485

Annotations

LeishMANIAdb annotations

An enormously expanded group of various amino acid transporters.. Localization: Cell surface (by feature)

Annotations by Jardim et al.

Transporters, amino acid permease AAT22

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	yes	yes: 8
Forrest at al. (procyclic)	yes	yes: 10
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 72

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 5

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 1, no: 177
NetGPI	no	yes: 0, no: 178

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0005737	cytoplasm	2	1
GO:0005886	plasma membrane	3	1
GO:0016020	membrane	2	161
GO:0020016	ciliary pocket	2	1
GO:0020023	kinetoplast	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	161

Expansion

Sequence features

A4HZQ0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HZQ0

Function

Biological processes
Term	Name	Level	Count
GO:0003333	amino acid transmembrane transport	5	17
GO:0006810	transport	3	17
GO:0006811	monoatomic ion transport	4	1
GO:0006812	monoatomic cation transport	5	1
GO:0006820	monoatomic anion transport	5	1
GO:0006865	amino acid transport	5	17
GO:0009987	cellular process	1	17
GO:0015711	organic anion transport	5	1
GO:0015802	basic amino acid transport	6	1
GO:0015819	lysine transport	6	1
GO:0015849	organic acid transport	5	17
GO:0046942	carboxylic acid transport	6	1
GO:0051179	localization	1	17
GO:0051234	establishment of localization	2	17
GO:0055085	transmembrane transport	2	17
GO:0071702	organic substance transport	4	17
GO:0071705	nitrogen compound transport	4	17
GO:1903825	organic acid transmembrane transport	3	17
GO:1905039	carboxylic acid transmembrane transport	4	17

Molecular functions
Term	Name	Level	Count
GO:0005215	transporter activity	1	17
GO:0005342	organic acid transmembrane transporter activity	3	17
GO:0008324	monoatomic cation transmembrane transporter activity	4	1
GO:0008509	monoatomic anion transmembrane transporter activity	4	1
GO:0008514	organic anion transmembrane transporter activity	5	1
GO:0015075	monoatomic ion transmembrane transporter activity	3	1
GO:0015171	amino acid transmembrane transporter activity	5	17
GO:0015174	basic amino acid transmembrane transporter activity	6	1
GO:0015179	L-amino acid transmembrane transporter activity	6	17
GO:0015189	L-lysine transmembrane transporter activity	5	1
GO:0022857	transmembrane transporter activity	2	17
GO:0046943	carboxylic acid transmembrane transporter activity	4	17

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	82	84	PF00675	0.450
CLV_PCSK_KEX2_1	82	84	PF00082	0.402
CLV_PCSK_SKI1_1	156	160	PF00082	0.323
CLV_PCSK_SKI1_1	210	214	PF00082	0.359
CLV_PCSK_SKI1_1	349	353	PF00082	0.522
DOC_ANK_TNKS_1	82	89	PF00023	0.566
DOC_CYCLIN_RxL_1	261	274	PF00134	0.375
DOC_CYCLIN_yCln2_LP_2	107	113	PF00134	0.383
DOC_CYCLIN_yCln2_LP_2	220	226	PF00134	0.324
DOC_MAPK_FxFP_2	436	439	PF00069	0.393
DOC_MAPK_MEF2A_6	308	316	PF00069	0.519
DOC_PP1_RVXF_1	154	160	PF00149	0.516
DOC_PP1_RVXF_1	202	209	PF00149	0.377
DOC_PP2B_LxvP_1	107	110	PF13499	0.378
DOC_PP2B_LxvP_1	220	223	PF13499	0.335
DOC_PP2B_LxvP_1	224	227	PF13499	0.335
DOC_PP2B_LxvP_1	414	417	PF13499	0.349
DOC_PP4_FxxP_1	436	439	PF00568	0.358
DOC_USP7_MATH_1	303	307	PF00917	0.558
DOC_USP7_MATH_1	98	102	PF00917	0.409
DOC_WW_Pin1_4	23	28	PF00397	0.715
DOC_WW_Pin1_4	299	304	PF00397	0.519
LIG_14-3-3_CanoR_1	204	209	PF00244	0.297
LIG_14-3-3_CanoR_1	210	216	PF00244	0.346
LIG_14-3-3_CanoR_1	228	234	PF00244	0.502
LIG_14-3-3_CanoR_1	349	358	PF00244	0.345
LIG_Actin_WH2_2	219	236	PF00022	0.328
LIG_Actin_WH2_2	245	263	PF00022	0.341
LIG_Actin_WH2_2	437	454	PF00022	0.383
LIG_BIR_II_1	1	5	PF00653	0.806
LIG_BRCT_BRCA1_1	204	208	PF00533	0.301
LIG_BRCT_BRCA1_1	213	217	PF00533	0.350
LIG_BRCT_BRCA1_1	305	309	PF00533	0.539
LIG_BRCT_BRCA1_1	91	95	PF00533	0.495
LIG_deltaCOP1_diTrp_1	188	193	PF00928	0.387
LIG_EVH1_2	86	90	PF00568	0.611
LIG_FHA_1	113	119	PF00498	0.293
LIG_FHA_1	120	126	PF00498	0.346
LIG_FHA_1	152	158	PF00498	0.456
LIG_FHA_1	165	171	PF00498	0.257
LIG_FHA_1	214	220	PF00498	0.374
LIG_FHA_1	255	261	PF00498	0.401
LIG_FHA_1	476	482	PF00498	0.387
LIG_LIR_Gen_1	122	131	PF02991	0.405
LIG_LIR_Gen_1	164	173	PF02991	0.560
LIG_LIR_Gen_1	188	194	PF02991	0.290
LIG_LIR_Gen_1	205	215	PF02991	0.299
LIG_LIR_Gen_1	216	224	PF02991	0.343
LIG_LIR_Gen_1	232	243	PF02991	0.485
LIG_LIR_Gen_1	293	303	PF02991	0.321
LIG_LIR_Gen_1	403	411	PF02991	0.339
LIG_LIR_Gen_1	430	441	PF02991	0.454
LIG_LIR_Gen_1	51	60	PF02991	0.748
LIG_LIR_Gen_1	6	12	PF02991	0.736
LIG_LIR_Nem_3	122	127	PF02991	0.386
LIG_LIR_Nem_3	164	169	PF02991	0.524
LIG_LIR_Nem_3	188	193	PF02991	0.261
LIG_LIR_Nem_3	205	211	PF02991	0.298
LIG_LIR_Nem_3	214	220	PF02991	0.335
LIG_LIR_Nem_3	232	238	PF02991	0.493
LIG_LIR_Nem_3	293	299	PF02991	0.350
LIG_LIR_Nem_3	306	312	PF02991	0.454
LIG_LIR_Nem_3	322	327	PF02991	0.376
LIG_LIR_Nem_3	328	333	PF02991	0.359
LIG_LIR_Nem_3	352	358	PF02991	0.309
LIG_LIR_Nem_3	403	407	PF02991	0.333
LIG_LIR_Nem_3	421	426	PF02991	0.293
LIG_LIR_Nem_3	430	436	PF02991	0.385
LIG_LIR_Nem_3	480	485	PF02991	0.462
LIG_LIR_Nem_3	51	56	PF02991	0.711
LIG_NRBOX	406	412	PF00104	0.315
LIG_PCNA_yPIPBox_3	397	405	PF02747	0.551
LIG_Pex14_1	326	330	PF04695	0.368
LIG_Pex14_2	239	243	PF04695	0.352
LIG_Pex14_2	285	289	PF04695	0.341
LIG_Pex14_2	429	433	PF04695	0.414
LIG_Pex14_2	438	442	PF04695	0.415
LIG_PTB_Apo_2	1	8	PF02174	0.603
LIG_PTB_Phospho_1	1	7	PF10480	0.605
LIG_SH2_CRK	203	207	PF00017	0.391
LIG_SH2_CRK	348	352	PF00017	0.305
LIG_SH2_GRB2like	456	459	PF00017	0.608
LIG_SH2_PTP2	235	238	PF00017	0.393
LIG_SH2_PTP2	360	363	PF00017	0.374
LIG_SH2_SRC	124	127	PF00017	0.359
LIG_SH2_STAP1	134	138	PF00017	0.389
LIG_SH2_STAP1	151	155	PF00017	0.511
LIG_SH2_STAT5	124	127	PF00017	0.339
LIG_SH2_STAT5	129	132	PF00017	0.354
LIG_SH2_STAT5	182	185	PF00017	0.337
LIG_SH2_STAT5	235	238	PF00017	0.371
LIG_SH2_STAT5	246	249	PF00017	0.350
LIG_SH2_STAT5	333	336	PF00017	0.367
LIG_SH2_STAT5	355	358	PF00017	0.355
LIG_SH2_STAT5	360	363	PF00017	0.397
LIG_SH2_STAT5	459	462	PF00017	0.496
LIG_SH2_STAT5	7	10	PF00017	0.759
LIG_SH3_3	64	70	PF00018	0.714
LIG_SH3_3	81	87	PF00018	0.638
LIG_SH3_5	350	354	PF00018	0.387
LIG_SUMO_SIM_anti_2	216	222	PF11976	0.381
LIG_SUMO_SIM_anti_2	403	409	PF11976	0.305
LIG_SUMO_SIM_par_1	129	135	PF11976	0.357
LIG_TYR_ITIM	233	238	PF00017	0.374
LIG_TYR_ITIM	244	249	PF00017	0.360
LIG_TYR_ITIM	358	363	PF00017	0.370
LIG_TYR_ITSM	120	127	PF00017	0.391
LIG_TYR_ITSM	478	485	PF00017	0.430
LIG_UBA3_1	138	145	PF00899	0.361
LIG_UBA3_1	170	174	PF00899	0.382
LIG_Vh1_VBS_1	238	256	PF01044	0.349
LIG_WRC_WIRS_1	401	406	PF05994	0.393
LIG_WRC_WIRS_1	426	431	PF05994	0.373
MOD_CDK_SPK_2	299	304	PF00069	0.378
MOD_CK1_1	378	384	PF00069	0.346
MOD_CK1_1	406	412	PF00069	0.388
MOD_GlcNHglycan	114	118	PF01048	0.340
MOD_GlcNHglycan	254	257	PF01048	0.409
MOD_GlcNHglycan	28	31	PF01048	0.626
MOD_GlcNHglycan	445	448	PF01048	0.368
MOD_GlcNHglycan	91	94	PF01048	0.349
MOD_GSK3_1	143	150	PF00069	0.347
MOD_GSK3_1	19	26	PF00069	0.722
MOD_GSK3_1	299	306	PF00069	0.398
MOD_N-GLC_1	299	304	PF02516	0.341
MOD_NEK2_1	113	118	PF00069	0.339
MOD_NEK2_1	271	276	PF00069	0.355
MOD_NEK2_1	290	295	PF00069	0.356
MOD_NEK2_1	319	324	PF00069	0.382
MOD_NEK2_1	425	430	PF00069	0.343
MOD_NEK2_1	443	448	PF00069	0.368
MOD_NEK2_1	475	480	PF00069	0.307
MOD_NEK2_1	97	102	PF00069	0.371
MOD_NEK2_2	129	134	PF00069	0.367
MOD_PIKK_1	19	25	PF00454	0.658
MOD_PKA_2	378	384	PF00069	0.388
MOD_Plk_1	38	44	PF00069	0.536
MOD_Plk_1	5	11	PF00069	0.744
MOD_Plk_4	119	125	PF00069	0.342
MOD_Plk_4	129	135	PF00069	0.344
MOD_Plk_4	213	219	PF00069	0.363
MOD_Plk_4	234	240	PF00069	0.328
MOD_Plk_4	314	320	PF00069	0.333
MOD_Plk_4	340	346	PF00069	0.319
MOD_Plk_4	400	406	PF00069	0.312
MOD_Plk_4	418	424	PF00069	0.321
MOD_Plk_4	468	474	PF00069	0.342
MOD_Plk_4	477	483	PF00069	0.345
MOD_Plk_4	5	11	PF00069	0.661
MOD_ProDKin_1	23	29	PF00069	0.646
MOD_ProDKin_1	299	305	PF00069	0.374
MOD_SUMO_rev_2	39	49	PF00179	0.647
MOD_SUMO_rev_2	446	454	PF00179	0.200
TRG_DiLeu_BaEn_1	311	316	PF01217	0.198
TRG_DiLeu_BaLyEn_6	134	139	PF01217	0.413
TRG_ENDOCYTIC_2	124	127	PF00928	0.371
TRG_ENDOCYTIC_2	203	206	PF00928	0.475
TRG_ENDOCYTIC_2	235	238	PF00928	0.370
TRG_ENDOCYTIC_2	246	249	PF00928	0.362
TRG_ENDOCYTIC_2	296	299	PF00928	0.307
TRG_ENDOCYTIC_2	333	336	PF00928	0.343
TRG_ENDOCYTIC_2	348	351	PF00928	0.322
TRG_ENDOCYTIC_2	355	358	PF00928	0.360
TRG_ENDOCYTIC_2	360	363	PF00928	0.367
TRG_ENDOCYTIC_2	457	460	PF00928	0.351
TRG_ENDOCYTIC_2	482	485	PF00928	0.481
TRG_ENDOCYTIC_2	7	10	PF00928	0.716
TRG_ER_diArg_1	15	18	PF00400	0.736
TRG_ER_diArg_1	81	83	PF00400	0.574
TRG_Pf-PMV_PEXEL_1	349	353	PF00026	0.440

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P285	Leptomonas seymouri	33%	99%
A0A0N0P5D2	Leptomonas seymouri	43%	100%
A0A0N0P613	Leptomonas seymouri	29%	100%
A0A0N0P6F6	Leptomonas seymouri	73%	100%
A0A0N0P8T9	Leptomonas seymouri	42%	97%
A0A0N0P955	Leptomonas seymouri	40%	100%
A0A0N1I2L5	Leptomonas seymouri	40%	100%
A0A0N1I3F8	Leptomonas seymouri	44%	91%
A0A0N1I3H4	Leptomonas seymouri	42%	88%
A0A0N1I8K7	Leptomonas seymouri	37%	99%
A0A0N1I8W4	Leptomonas seymouri	31%	99%
A0A0N1I9T3	Leptomonas seymouri	42%	100%
A0A0N1IAJ0	Leptomonas seymouri	22%	100%
A0A0N1IMP2	Leptomonas seymouri	44%	96%
A0A0N1PA98	Leptomonas seymouri	35%	79%
A0A0N1PBP2	Leptomonas seymouri	41%	98%
A0A0N1PFD1	Leptomonas seymouri	42%	97%
A0A0S4IV32	Bodo saltans	25%	99%
A0A0S4JBX6	Bodo saltans	27%	91%
A0A0S4JCF0	Bodo saltans	22%	100%
A0A0S4JHM8	Bodo saltans	28%	100%
A0A0S4JPU4	Bodo saltans	23%	99%
A0A0S4JQ87	Bodo saltans	30%	100%
A0A0S4JU02	Bodo saltans	40%	100%
A0A1X0NJR7	Trypanosomatidae	44%	98%
A0A1X0NKS5	Trypanosomatidae	44%	100%
A0A1X0NKV2	Trypanosomatidae	40%	97%
A0A1X0NKW7	Trypanosomatidae	43%	100%
A0A1X0NLA5	Trypanosomatidae	22%	100%
A0A1X0NNX9	Trypanosomatidae	62%	100%
A0A1X0NPV3	Trypanosomatidae	40%	100%
A0A1X0NQH3	Trypanosomatidae	42%	100%
A0A1X0NR26	Trypanosomatidae	45%	100%
A0A1X0NRL3	Trypanosomatidae	46%	100%
A0A1X0NRL7	Trypanosomatidae	44%	100%
A0A1X0NYI3	Trypanosomatidae	40%	98%
A0A1X0P4S1	Trypanosomatidae	24%	100%
A0A1X0P814	Trypanosomatidae	40%	99%
A0A1X0P9N8	Trypanosomatidae	33%	100%
A0A3Q8ICL1	Leishmania donovani	37%	80%
A0A3Q8ID74	Leishmania donovani	39%	91%
A0A3Q8IDG8	Leishmania donovani	40%	100%
A0A3Q8IEP8	Leishmania donovani	40%	90%
A0A3Q8IFZ0	Leishmania donovani	39%	95%
A0A3Q8IG00	Leishmania donovani	44%	100%
A0A3Q8IGE6	Leishmania donovani	34%	83%
A0A3Q8IHG8	Leishmania donovani	41%	97%
A0A3Q8IJH2	Leishmania donovani	41%	100%
A0A3Q8IJX8	Leishmania donovani	38%	100%
A0A3Q8ILE0	Leishmania donovani	100%	100%
A0A3Q8IQG8	Leishmania donovani	32%	98%
A0A3R7JSA0	Trypanosoma rangeli	41%	100%
A0A3R7KDS3	Trypanosoma rangeli	43%	100%
A0A3R7MQD8	Trypanosoma rangeli	21%	100%
A0A3R7MWF1	Trypanosoma rangeli	24%	100%
A0A3R7N1H9	Trypanosoma rangeli	40%	99%
A0A3R7N2A2	Trypanosoma rangeli	42%	100%
A0A3R7R2W8	Trypanosoma rangeli	40%	100%
A0A3R7RFB5	Trypanosoma rangeli	58%	96%
A0A3R7RQX3	Trypanosoma rangeli	45%	100%
A0A3S5H6T4	Leishmania donovani	40%	96%
A0A3S5H7P4	Leishmania donovani	45%	95%
A0A3S5ISG3	Trypanosoma rangeli	46%	98%
A0A3S7WQ39	Leishmania donovani	43%	99%
A0A3S7X443	Leishmania donovani	45%	100%
A0A3S7X458	Leishmania donovani	45%	97%
A0A3S7X4A1	Leishmania donovani	38%	100%
A0A3S7X4L2	Leishmania donovani	38%	80%
A0A3S7X4N4	Leishmania donovani	38%	80%
A0A3S7X4P0	Leishmania donovani	37%	80%
A0A3S7XA86	Leishmania donovani	24%	100%
A0A3S7XCE3	Leishmania donovani	22%	100%
A0A422MW74	Trypanosoma rangeli	39%	95%
A0A422N5W8	Trypanosoma rangeli	24%	100%
A0A422N608	Trypanosoma rangeli	40%	99%
A0A422NBM3	Trypanosoma rangeli	46%	100%
A0A422NBQ2	Trypanosoma rangeli	45%	100%
A0A422NZS1	Trypanosoma rangeli	45%	100%
A1YG32	Pan paniscus	24%	96%
A2VCW5	Rattus norvegicus	26%	100%
A2VE31	Bos taurus	23%	96%
A4H565	Leishmania braziliensis	40%	100%
A4HC75	Leishmania braziliensis	81%	100%
A4HFJ2	Leishmania braziliensis	44%	100%
A4HFT5	Leishmania braziliensis	38%	100%
A4HJ06	Leishmania braziliensis	41%	100%
A4HJ07	Leishmania braziliensis	41%	100%
A4HJ09	Leishmania braziliensis	41%	100%
A4HJ10	Leishmania braziliensis	40%	100%
A4HJ35	Leishmania braziliensis	45%	100%
A4HJ36	Leishmania braziliensis	40%	100%
A4HJ37	Leishmania braziliensis	41%	100%
A4HJ63	Leishmania braziliensis	39%	100%
A4HJF8	Leishmania braziliensis	39%	79%
A4HJF9	Leishmania braziliensis	40%	83%
A4HJG1	Leishmania braziliensis	40%	83%
A4HJG3	Leishmania braziliensis	38%	79%
A4HJG5	Leishmania braziliensis	39%	79%
A4HKQ7	Leishmania braziliensis	44%	100%
A4HNJ6	Leishmania braziliensis	24%	100%
A4HNJ7	Leishmania braziliensis	25%	100%
A4HNQ0	Leishmania braziliensis	31%	100%
A4HTE2	Leishmania infantum	38%	99%
A4I2V2	Leishmania infantum	38%	82%
A4I6F1	Leishmania infantum	45%	95%
A4I6F2	Leishmania infantum	40%	90%
A4I6I1	Leishmania infantum	38%	100%
A4I6J8	Leishmania infantum	38%	91%
A4I6J9	Leishmania infantum	45%	100%
A4I6K0	Leishmania infantum	39%	95%
A4I6L3	Leishmania infantum	44%	100%
A4I6L4	Leishmania infantum	38%	100%
A4I6W4	Leishmania infantum	38%	80%
A4I887	Leishmania infantum	40%	100%
A4IC53	Leishmania infantum	24%	100%
A4IC66	Leishmania infantum	26%	100%
A4ICC3	Leishmania infantum	22%	100%
A4ICU5	Leishmania infantum	32%	98%
A6NNN8	Homo sapiens	24%	100%
A7E3U5	Bos taurus	25%	100%
C9ZMB9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
C9ZMD1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	99%
C9ZMD2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
C9ZMD3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	99%
C9ZMD4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	100%
C9ZN51	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	44%	100%
C9ZN59	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	100%
C9ZN60	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
C9ZVS1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	93%
C9ZVS2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	90%
C9ZVS3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	92%
C9ZWQ7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	100%
C9ZWQ8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
C9ZWQ9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	100%
C9ZWR0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
C9ZWR1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	89%
C9ZWR7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	100%
C9ZWX2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
C9ZWX3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
C9ZWX4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
C9ZWX5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	100%
C9ZWX6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
C9ZWX7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
C9ZWY0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	100%
C9ZWY1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
D0A362	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	100%
D0AAF6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	45%	100%
D0AAF8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	45%	100%
D0AAG7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	98%
D0AAG8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	98%
E8NHF9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	43%	100%
E8NHS7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	100%
E9AD44	Leishmania major	40%	100%
E9AD45	Leishmania major	38%	100%
E9ADD7	Leishmania major	42%	100%
E9AG08	Leishmania major	24%	100%
E9AG09	Leishmania major	26%	100%
E9AHD7	Leishmania infantum	45%	97%
E9AHD9	Leishmania infantum	39%	91%
E9AHK8	Leishmania infantum	43%	100%
E9AHL1	Leishmania infantum	38%	80%
E9AHL2	Leishmania infantum	36%	100%
E9AHL3	Leishmania infantum	37%	80%
E9ALD5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	39%	100%
E9ASF9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	100%
E9AUB8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	100%
E9AVK6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
E9AYW8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	100%
E9AYW9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	41%	100%
E9AZ62	Leishmania mexicana (strain MHOM/GT/2001/U1103)	39%	100%
E9B1I4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	43%	100%
E9B1I6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	100%
E9B1K7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	100%
E9B1K8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	100%
E9B1K9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	100%
E9B1N8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	41%	100%
E9B1N9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	37%	100%
E9B1Y0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	100%
E9B345	Leishmania mexicana (strain MHOM/GT/2001/U1103)	41%	100%
E9B761	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	100%
E9B762	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
F4ILY9	Arabidopsis thaliana	25%	100%
F4IUW3	Arabidopsis thaliana	26%	88%
F4IZW8	Arabidopsis thaliana	23%	92%
F4JE35	Arabidopsis thaliana	26%	90%
F4KBM7	Arabidopsis thaliana	24%	100%
G3UVW3	Mus musculus	26%	100%
O22719	Arabidopsis thaliana	23%	100%
O74327	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	28%	100%
O80668	Arabidopsis thaliana	23%	90%
P34479	Caenorhabditis elegans	22%	100%
P36062	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	21%	70%
P39981	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	24%	100%
Q0WQJ3	Arabidopsis thaliana	27%	100%
Q1PER9	Arabidopsis thaliana	23%	93%
Q28HE5	Xenopus tropicalis	27%	100%
Q28I47	Xenopus tropicalis	23%	100%
Q3U1J0	Mus musculus	25%	100%
Q4Q072	Leishmania major	22%	100%
Q4Q236	Leishmania major	33%	100%
Q4Q509	Leishmania major	42%	100%
Q4Q680	Leishmania major	34%	100%
Q4Q682	Leishmania major	38%	83%
Q4Q683	Leishmania major	34%	100%
Q4Q6H5	Leishmania major	38%	100%
Q4Q6K5	Leishmania major	40%	100%
Q4Q6K6	Leishmania major	40%	98%
Q4Q6M8	Leishmania major	39%	100%
Q4Q6M9	Leishmania major	42%	100%
Q4Q6N0	Leishmania major	39%	100%
Q4Q6N1	Leishmania major	37%	100%
Q4QBX3	Leishmania major	96%	100%
Q4QIH0	Leishmania major	39%	100%
Q503G8	Danio rerio	28%	100%
Q5E9S9	Bos taurus	25%	100%
Q5F468	Gallus gallus	25%	97%
Q5HZH7	Mus musculus	24%	100%
Q5R443	Pongo abelii	26%	100%
Q5R9F5	Pongo abelii	26%	100%
Q5RE87	Pongo abelii	24%	89%
Q5SPB1	Danio rerio	25%	96%
Q5XH90	Xenopus tropicalis	24%	98%
Q6DEL1	Danio rerio	26%	100%
Q6DFE7	Xenopus laevis	26%	100%
Q6JWR2	Rattus norvegicus	26%	100%
Q6WWW3	Rattus norvegicus	25%	100%
Q8BWH0	Mus musculus	26%	100%
Q8CFE6	Mus musculus	24%	96%
Q8GYS4	Arabidopsis thaliana	26%	88%
Q8IZM9	Homo sapiens	27%	100%
Q8K2P7	Mus musculus	25%	100%
Q8LPF4	Arabidopsis thaliana	27%	92%
Q8WUX1	Homo sapiens	25%	100%
Q969I6	Homo sapiens	24%	89%
Q96QD8	Homo sapiens	24%	96%
Q99624	Homo sapiens	25%	96%
Q9DCP2	Mus musculus	26%	96%
Q9EQ25	Rattus norvegicus	23%	89%
Q9FKS8	Arabidopsis thaliana	25%	100%
Q9H2H9	Homo sapiens	26%	100%
Q9JHE5	Rattus norvegicus	25%	96%
Q9JHZ9	Rattus norvegicus	26%	96%
Q9JM15	Rattus norvegicus	24%	100%
Q9LI61	Arabidopsis thaliana	24%	100%
Q9LYM2	Arabidopsis thaliana	26%	100%
Q9M8L9	Arabidopsis thaliana	24%	99%
Q9NVC3	Homo sapiens	26%	100%
Q9SF09	Arabidopsis thaliana	25%	100%
Q9SVG0	Arabidopsis thaliana	24%	100%
V5AXD0	Trypanosoma cruzi	25%	100%
V5AZP2	Trypanosoma cruzi	40%	80%
V5B9A6	Trypanosoma cruzi	44%	100%
V5BA72	Trypanosoma cruzi	45%	100%
V5BH70	Trypanosoma cruzi	55%	100%
V5BIJ1	Trypanosoma cruzi	43%	87%
V5BMG4	Trypanosoma cruzi	44%	100%
V5BTX5	Trypanosoma cruzi	26%	96%
V5D7K9	Trypanosoma cruzi	43%	100%
V5DCG4	Trypanosoma cruzi	39%	100%
V5DKR4	Trypanosoma cruzi	43%	100%