Perilipin-3-like

Quick info Annotations Localization Phosphorylation Abundance Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Perilipin-3-like

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HZP6_LEIIN

TriTrypDb:

LINF_220006800

Length:

260

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Phosphorylation

Amastigote: 129, 23, 39, 41, 67

Abundance

Amastigote (protein)


Source	Evidence on protein	Close homologs
Pescher et al. (upgregulation)	no	yes: 0

Promastigote and amastigote


Source	Evidence on protein	Close homologs
Lahav et al. - mRNA - Protein

Expansion

Sequence features

A4HZP6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HZP6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	16	20	PF00656	0.583
CLV_NRD_NRD_1	101	103	PF00675	0.458
DOC_USP7_MATH_1	119	123	PF00917	0.635
DOC_USP7_MATH_1	126	130	PF00917	0.624
DOC_USP7_MATH_1	154	158	PF00917	0.644
DOC_USP7_MATH_1	36	40	PF00917	0.567
DOC_USP7_UBL2_3	147	151	PF12436	0.585
LIG_14-3-3_CanoR_1	120	124	PF00244	0.650
LIG_14-3-3_CanoR_1	127	134	PF00244	0.593
LIG_14-3-3_CanoR_1	145	155	PF00244	0.522
LIG_14-3-3_CanoR_1	186	192	PF00244	0.436
LIG_14-3-3_CanoR_1	212	218	PF00244	0.447
LIG_14-3-3_CanoR_1	74	83	PF00244	0.635
LIG_14-3-3_CterR_2	256	260	PF00244	0.453
LIG_CORNRBOX	173	181	PF00104	0.215
LIG_FHA_1	186	192	PF00498	0.436
LIG_FHA_1	231	237	PF00498	0.380
LIG_LIR_Gen_1	157	164	PF02991	0.642
LIG_LIR_Gen_1	167	177	PF02991	0.229
LIG_LIR_Nem_3	157	162	PF02991	0.646
LIG_LIR_Nem_3	167	173	PF02991	0.229
LIG_RPA_C_Fungi	115	127	PF08784	0.586
LIG_SH2_NCK_1	250	254	PF00017	0.510
LIG_SH2_SRC	108	111	PF00017	0.530
LIG_SH2_STAT5	108	111	PF00017	0.571
LIG_SH2_STAT5	155	158	PF00017	0.510
LIG_SH2_STAT5	182	185	PF00017	0.279
LIG_SH2_STAT5	250	253	PF00017	0.489
LIG_SH2_STAT5	68	71	PF00017	0.567
LIG_SH2_STAT5	97	100	PF00017	0.532
LIG_SH3_3	220	226	PF00018	0.592
LIG_UBA3_1	197	204	PF00899	0.528
MOD_CK1_1	248	254	PF00069	0.441
MOD_GlcNHglycan	110	113	PF01048	0.521
MOD_GlcNHglycan	117	120	PF01048	0.522
MOD_GlcNHglycan	128	131	PF01048	0.533
MOD_GlcNHglycan	192	195	PF01048	0.500
MOD_GlcNHglycan	40	43	PF01048	0.433
MOD_GSK3_1	115	122	PF00069	0.691
MOD_GSK3_1	139	146	PF00069	0.710
MOD_GSK3_1	245	252	PF00069	0.573
MOD_N-GLC_2	238	240	PF02516	0.506
MOD_NEK2_1	162	167	PF00069	0.527
MOD_PIKK_1	149	155	PF00454	0.569
MOD_PIKK_1	185	191	PF00454	0.553
MOD_PIKK_1	20	26	PF00454	0.574
MOD_PIKK_1	245	251	PF00454	0.571
MOD_PKA_2	119	125	PF00069	0.573
MOD_PKA_2	126	132	PF00069	0.495
MOD_PKA_2	185	191	PF00069	0.553
MOD_PKA_2	4	10	PF00069	0.555
MOD_Plk_4	176	182	PF00069	0.243
MOD_Plk_4	213	219	PF00069	0.561
MOD_Plk_4	64	70	PF00069	0.569
MOD_SUMO_rev_2	77	81	PF00179	0.555
TRG_ENDOCYTIC_2	159	162	PF00928	0.681
TRG_ER_diArg_1	2	5	PF00400	0.590
TRG_NES_CRM1_1	16	31	PF08389	0.499

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBW9	Leptomonas seymouri	48%	100%
A0A3Q8IE48	Leishmania donovani	100%	100%
A4HC71	Leishmania braziliensis	79%	100%
E9AVK2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	100%
Q4QBX7	Leishmania major	90%	100%