LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

BAR domain-containing protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
BAR domain-containing protein
Gene product:
BAR domain containing protein - putative
Species:
Leishmania infantum
UniProt:
A4HZL5_LEIIN
TriTrypDb:
LINF_210005600
Length:
245

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 8
Forrest at al. (procyclic) no yes: 6
Silverman et al. no yes: 0
Pissara et al. no yes: 24
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 5
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 10
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 27
NetGPI no yes: 0, no: 27
Cellular components
Term Name Level Count
GO:0005737 cytoplasm 2 1
GO:0005886 plasma membrane 3 1
GO:0016020 membrane 2 1
GO:0031090 organelle membrane 3 1
GO:0031253 cell projection membrane 4 1
GO:0060170 ciliary membrane 5 1
GO:0098588 bounding membrane of organelle 4 1
GO:0098590 plasma membrane region 3 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

A4HZL5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HZL5

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 197 201 PF00656 0.292
CLV_NRD_NRD_1 150 152 PF00675 0.561
CLV_NRD_NRD_1 168 170 PF00675 0.368
CLV_NRD_NRD_1 24 26 PF00675 0.495
CLV_NRD_NRD_1 51 53 PF00675 0.536
CLV_PCSK_FUR_1 24 28 PF00082 0.500
CLV_PCSK_KEX2_1 127 129 PF00082 0.524
CLV_PCSK_KEX2_1 168 170 PF00082 0.417
CLV_PCSK_KEX2_1 24 26 PF00082 0.402
CLV_PCSK_KEX2_1 51 53 PF00082 0.498
CLV_PCSK_PC1ET2_1 127 129 PF00082 0.488
CLV_PCSK_PC1ET2_1 26 28 PF00082 0.422
CLV_PCSK_PC7_1 123 129 PF00082 0.291
CLV_PCSK_SKI1_1 154 158 PF00082 0.406
CLV_PCSK_SKI1_1 194 198 PF00082 0.456
CLV_PCSK_SKI1_1 27 31 PF00082 0.444
CLV_PCSK_SKI1_1 8 12 PF00082 0.462
DEG_Nend_UBRbox_2 1 3 PF02207 0.486
DOC_CYCLIN_RxL_1 151 159 PF00134 0.347
DOC_MAPK_gen_1 6 13 PF00069 0.558
DOC_USP7_MATH_1 102 106 PF00917 0.453
DOC_USP7_MATH_1 175 179 PF00917 0.468
DOC_USP7_MATH_1 204 208 PF00917 0.376
DOC_USP7_MATH_1 35 39 PF00917 0.412
DOC_USP7_MATH_1 46 50 PF00917 0.425
DOC_USP7_UBL2_3 154 158 PF12436 0.481
DOC_USP7_UBL2_3 26 30 PF12436 0.295
DOC_USP7_UBL2_3 8 12 PF12436 0.470
LIG_14-3-3_CanoR_1 151 157 PF00244 0.369
LIG_14-3-3_CanoR_1 194 202 PF00244 0.332
LIG_Actin_WH2_2 209 226 PF00022 0.494
LIG_BRCT_BRCA1_1 60 64 PF00533 0.433
LIG_FHA_1 109 115 PF00498 0.508
LIG_FHA_1 145 151 PF00498 0.308
LIG_FHA_1 197 203 PF00498 0.536
LIG_FHA_2 135 141 PF00498 0.505
LIG_FHA_2 15 21 PF00498 0.468
LIG_FHA_2 195 201 PF00498 0.561
LIG_FHA_2 39 45 PF00498 0.419
LIG_LIR_Apic_2 226 232 PF02991 0.346
LIG_LIR_Gen_1 61 71 PF02991 0.463
LIG_LIR_Nem_3 134 138 PF02991 0.417
LIG_LIR_Nem_3 61 67 PF02991 0.373
LIG_LIR_Nem_3 94 99 PF02991 0.450
LIG_LYPXL_yS_3 70 73 PF13949 0.334
LIG_Rb_pABgroove_1 112 120 PF01858 0.314
LIG_SH2_PTP2 229 232 PF00017 0.344
LIG_SH2_STAP1 162 166 PF00017 0.461
LIG_SH2_STAT5 149 152 PF00017 0.341
LIG_SH2_STAT5 229 232 PF00017 0.344
LIG_SH3_3 68 74 PF00018 0.521
LIG_Sin3_3 81 88 PF02671 0.249
LIG_UBA3_1 4 12 PF00899 0.572
MOD_CK1_1 207 213 PF00069 0.320
MOD_CK1_1 38 44 PF00069 0.432
MOD_CK2_1 134 140 PF00069 0.461
MOD_CK2_1 14 20 PF00069 0.512
MOD_CK2_1 38 44 PF00069 0.443
MOD_GlcNHglycan 177 180 PF01048 0.480
MOD_GlcNHglycan 214 219 PF01048 0.361
MOD_GlcNHglycan 33 36 PF01048 0.462
MOD_GSK3_1 102 109 PF00069 0.412
MOD_GSK3_1 140 147 PF00069 0.474
MOD_GSK3_1 152 159 PF00069 0.456
MOD_GSK3_1 190 197 PF00069 0.419
MOD_GSK3_1 31 38 PF00069 0.436
MOD_NEK2_1 103 108 PF00069 0.318
MOD_NEK2_1 150 155 PF00069 0.456
MOD_NEK2_1 156 161 PF00069 0.437
MOD_NEK2_1 190 195 PF00069 0.536
MOD_NEK2_1 84 89 PF00069 0.467
MOD_NEK2_2 46 51 PF00069 0.571
MOD_PKA_1 144 150 PF00069 0.423
MOD_PKA_2 150 156 PF00069 0.510
MOD_Plk_1 103 109 PF00069 0.410
MOD_Plk_2-3 134 140 PF00069 0.463
MOD_Plk_4 103 109 PF00069 0.396
MOD_Plk_4 152 158 PF00069 0.383
MOD_SUMO_rev_2 177 183 PF00179 0.543
TRG_ENDOCYTIC_2 70 73 PF00928 0.461
TRG_ER_diArg_1 24 27 PF00400 0.502
TRG_ER_diArg_1 50 52 PF00400 0.315
TRG_Pf-PMV_PEXEL_1 51 55 PF00026 0.496

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P4S1 Leptomonas seymouri 56% 100%
A0A0N1PD85 Leptomonas seymouri 34% 100%
A0A0N1PG41 Leptomonas seymouri 24% 77%
A0A1X0NEE3 Trypanosomatidae 24% 89%
A0A1X0NFG5 Trypanosomatidae 24% 89%
A0A1X0NXA6 Trypanosomatidae 27% 81%
A0A1X0NXA8 Trypanosomatidae 36% 100%
A0A3Q8IKU7 Leishmania donovani 32% 100%
A0A3S5H792 Leishmania donovani 100% 100%
A0A3S5H7I1 Leishmania donovani 24% 72%
A0A422MZP2 Trypanosoma rangeli 27% 81%
A4HBJ9 Leishmania braziliensis 34% 100%
A4HBK0 Leishmania braziliensis 63% 100%
A4HFU7 Leishmania braziliensis 22% 72%
A4HZL6 Leishmania infantum 32% 100%
A4I2W4 Leishmania infantum 24% 72%
E9ADF0 Leishmania major 21% 72%
E9AHL0 Leishmania infantum 24% 79%
E9AUW8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 32% 100%
E9AUW9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%
E9AZ74 Leishmania mexicana (strain MHOM/GT/2001/U1103) 24% 72%
Q4Q6I6 Leishmania major 25% 100%
Q4QCL3 Leishmania major 87% 100%
Q4QCL4 Leishmania major 32% 100%
V5BG41 Trypanosoma cruzi 38% 100%
V5BKK3 Trypanosoma cruzi 25% 81%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS