Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HZJ1_LEIIN

TriTrypDb:

LINF_210028300

Length:

1013

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HZJ1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HZJ1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	123	127	PF00656	0.559
CLV_C14_Caspase3-7	34	38	PF00656	0.546
CLV_C14_Caspase3-7	54	58	PF00656	0.506
CLV_C14_Caspase3-7	628	632	PF00656	0.379
CLV_C14_Caspase3-7	636	640	PF00656	0.394
CLV_C14_Caspase3-7	64	68	PF00656	0.527
CLV_C14_Caspase3-7	840	844	PF00656	0.535
CLV_NRD_NRD_1	217	219	PF00675	0.554
CLV_NRD_NRD_1	358	360	PF00675	0.404
CLV_NRD_NRD_1	4	6	PF00675	0.520
CLV_NRD_NRD_1	447	449	PF00675	0.476
CLV_NRD_NRD_1	522	524	PF00675	0.485
CLV_NRD_NRD_1	615	617	PF00675	0.420
CLV_NRD_NRD_1	649	651	PF00675	0.393
CLV_NRD_NRD_1	725	727	PF00675	0.535
CLV_NRD_NRD_1	752	754	PF00675	0.530
CLV_PCSK_FUR_1	445	449	PF00082	0.466
CLV_PCSK_FUR_1	483	487	PF00082	0.429
CLV_PCSK_KEX2_1	216	218	PF00082	0.558
CLV_PCSK_KEX2_1	23	25	PF00082	0.516
CLV_PCSK_KEX2_1	266	268	PF00082	0.587
CLV_PCSK_KEX2_1	358	360	PF00082	0.422
CLV_PCSK_KEX2_1	363	365	PF00082	0.422
CLV_PCSK_KEX2_1	393	395	PF00082	0.622
CLV_PCSK_KEX2_1	447	449	PF00082	0.476
CLV_PCSK_KEX2_1	485	487	PF00082	0.426
CLV_PCSK_KEX2_1	522	524	PF00082	0.485
CLV_PCSK_KEX2_1	615	617	PF00082	0.420
CLV_PCSK_KEX2_1	648	650	PF00082	0.420
CLV_PCSK_KEX2_1	724	726	PF00082	0.531
CLV_PCSK_KEX2_1	752	754	PF00082	0.543
CLV_PCSK_KEX2_1	989	991	PF00082	0.510
CLV_PCSK_PC1ET2_1	23	25	PF00082	0.516
CLV_PCSK_PC1ET2_1	266	268	PF00082	0.556
CLV_PCSK_PC1ET2_1	363	365	PF00082	0.429
CLV_PCSK_PC1ET2_1	393	395	PF00082	0.617
CLV_PCSK_PC1ET2_1	485	487	PF00082	0.426
CLV_PCSK_PC1ET2_1	724	726	PF00082	0.385
CLV_PCSK_PC1ET2_1	989	991	PF00082	0.437
CLV_PCSK_PC7_1	359	365	PF00082	0.407
CLV_PCSK_PC7_1	721	727	PF00082	0.517
CLV_PCSK_SKI1_1	24	28	PF00082	0.514
CLV_PCSK_SKI1_1	390	394	PF00082	0.667
CLV_PCSK_SKI1_1	473	477	PF00082	0.510
CLV_PCSK_SKI1_1	510	514	PF00082	0.484
CLV_PCSK_SKI1_1	692	696	PF00082	0.450
CLV_PCSK_SKI1_1	776	780	PF00082	0.580
CLV_PCSK_SKI1_1	910	914	PF00082	0.577
DEG_APCC_DBOX_1	409	417	PF00400	0.482
DEG_Nend_UBRbox_2	1	3	PF02207	0.533
DEG_SPOP_SBC_1	28	32	PF00917	0.528
DEG_SPOP_SBC_1	769	773	PF00917	0.551
DEG_SPOP_SBC_1	869	873	PF00917	0.551
DOC_ANK_TNKS_1	648	655	PF00023	0.422
DOC_CYCLIN_RxL_1	112	123	PF00134	0.535
DOC_CYCLIN_RxL_1	773	783	PF00134	0.540
DOC_MAPK_gen_1	410	418	PF00069	0.485
DOC_MAPK_MEF2A_6	955	963	PF00069	0.400
DOC_PP2B_LxvP_1	259	262	PF13499	0.498
DOC_PP2B_LxvP_1	416	419	PF13499	0.513
DOC_PP2B_LxvP_1	778	781	PF13499	0.543
DOC_PP2B_LxvP_1	956	959	PF13499	0.421
DOC_USP7_MATH_1	136	140	PF00917	0.521
DOC_USP7_MATH_1	177	181	PF00917	0.559
DOC_USP7_MATH_1	211	215	PF00917	0.596
DOC_USP7_MATH_1	237	241	PF00917	0.611
DOC_USP7_MATH_1	255	259	PF00917	0.507
DOC_USP7_MATH_1	28	32	PF00917	0.497
DOC_USP7_MATH_1	285	289	PF00917	0.571
DOC_USP7_MATH_1	402	406	PF00917	0.451
DOC_USP7_MATH_1	560	564	PF00917	0.486
DOC_USP7_MATH_1	62	66	PF00917	0.532
DOC_USP7_MATH_1	758	762	PF00917	0.492
DOC_USP7_MATH_1	786	790	PF00917	0.635
DOC_USP7_MATH_1	801	805	PF00917	0.548
DOC_USP7_MATH_1	824	828	PF00917	0.584
DOC_USP7_MATH_1	832	836	PF00917	0.556
DOC_USP7_MATH_1	916	920	PF00917	0.530
DOC_USP7_MATH_1	924	928	PF00917	0.543
DOC_USP7_MATH_1	949	953	PF00917	0.561
DOC_WW_Pin1_4	182	187	PF00397	0.552
DOC_WW_Pin1_4	198	203	PF00397	0.538
DOC_WW_Pin1_4	233	238	PF00397	0.516
DOC_WW_Pin1_4	310	315	PF00397	0.541
DOC_WW_Pin1_4	383	388	PF00397	0.481
DOC_WW_Pin1_4	427	432	PF00397	0.565
DOC_WW_Pin1_4	475	480	PF00397	0.518
DOC_WW_Pin1_4	537	542	PF00397	0.482
DOC_WW_Pin1_4	615	620	PF00397	0.456
DOC_WW_Pin1_4	781	786	PF00397	0.636
DOC_WW_Pin1_4	797	802	PF00397	0.516
DOC_WW_Pin1_4	817	822	PF00397	0.512
DOC_WW_Pin1_4	861	866	PF00397	0.592
DOC_WW_Pin1_4	920	925	PF00397	0.610
DOC_WW_Pin1_4	939	944	PF00397	0.569
LIG_14-3-3_CanoR_1	121	126	PF00244	0.536
LIG_14-3-3_CanoR_1	141	151	PF00244	0.544
LIG_14-3-3_CanoR_1	167	174	PF00244	0.513
LIG_14-3-3_CanoR_1	358	367	PF00244	0.581
LIG_14-3-3_CanoR_1	432	441	PF00244	0.466
LIG_14-3-3_CanoR_1	473	482	PF00244	0.441
LIG_14-3-3_CanoR_1	792	796	PF00244	0.577
LIG_14-3-3_CanoR_1	933	941	PF00244	0.492
LIG_Actin_WH2_2	957	973	PF00022	0.373
LIG_BIR_III_2	308	312	PF00653	0.554
LIG_BRCT_BRCA1_1	863	867	PF00533	0.609
LIG_BRCT_BRCA1_1	972	976	PF00533	0.399
LIG_FHA_1	106	112	PF00498	0.531
LIG_FHA_1	428	434	PF00498	0.570
LIG_FHA_1	807	813	PF00498	0.729
LIG_FHA_1	882	888	PF00498	0.538
LIG_FHA_2	104	110	PF00498	0.503
LIG_FHA_2	243	249	PF00498	0.570
LIG_FHA_2	258	264	PF00498	0.495
LIG_FHA_2	618	624	PF00498	0.391
LIG_FHA_2	940	946	PF00498	0.515
LIG_Integrin_isoDGR_2	856	858	PF01839	0.587
LIG_LIR_Nem_3	456	462	PF02991	0.434
LIG_LIR_Nem_3	72	77	PF02991	0.505
LIG_MYND_1	667	671	PF01753	0.519
LIG_NRBOX	908	914	PF00104	0.427
LIG_NRBOX	960	966	PF00104	0.410
LIG_NRBOX	994	1000	PF00104	0.417
LIG_Pex14_1	581	585	PF04695	0.321
LIG_SH2_CRK	74	78	PF00017	0.499
LIG_SH2_STAP1	1000	1004	PF00017	0.399
LIG_SH2_STAT3	411	414	PF00017	0.462
LIG_SH2_STAT3	464	467	PF00017	0.416
LIG_SH2_STAT5	337	340	PF00017	0.592
LIG_SH2_STAT5	462	465	PF00017	0.413
LIG_SH2_STAT5	584	587	PF00017	0.459
LIG_SH2_STAT5	819	822	PF00017	0.534
LIG_SH3_3	171	177	PF00018	0.530
LIG_SH3_3	226	232	PF00018	0.577
LIG_SH3_3	294	300	PF00018	0.683
LIG_SH3_3	308	314	PF00018	0.543
LIG_SH3_3	340	346	PF00018	0.431
LIG_SH3_3	416	422	PF00018	0.523
LIG_SH3_3	535	541	PF00018	0.491
LIG_SH3_3	554	560	PF00018	0.459
LIG_SH3_3	818	824	PF00018	0.558
LIG_SH3_3	943	949	PF00018	0.494
LIG_SH3_CIN85_PxpxPR_1	797	802	PF14604	0.535
LIG_SUMO_SIM_anti_2	960	965	PF11976	0.409
LIG_SUMO_SIM_par_1	414	421	PF11976	0.516
LIG_SxIP_EBH_1	880	889	PF03271	0.513
LIG_TRAF2_1	453	456	PF00917	0.488
LIG_TRAF2_1	468	471	PF00917	0.339
LIG_TRAF2_1	603	606	PF00917	0.375
LIG_TRAF2_1	625	628	PF00917	0.365
LIG_TRAF2_1	762	765	PF00917	0.520
LIG_WRC_WIRS_1	495	500	PF05994	0.398
LIG_WRC_WIRS_1	596	601	PF05994	0.422
LIG_WW_3	185	189	PF00397	0.513
MOD_CDC14_SPxK_1	3	6	PF00782	0.523
MOD_CDC14_SPxK_1	618	621	PF00782	0.448
MOD_CDK_SPK_2	198	203	PF00069	0.548
MOD_CDK_SPK_2	383	388	PF00069	0.481
MOD_CDK_SPK_2	427	432	PF00069	0.565
MOD_CDK_SPK_2	797	802	PF00069	0.618
MOD_CDK_SPxK_1	182	188	PF00069	0.526
MOD_CDK_SPxK_1	615	621	PF00069	0.451
MOD_CDK_SPxxK_3	383	390	PF00069	0.468
MOD_CDK_SPxxK_3	781	788	PF00069	0.535
MOD_CK1_1	139	145	PF00069	0.555
MOD_CK1_1	236	242	PF00069	0.597
MOD_CK1_1	30	36	PF00069	0.707
MOD_CK1_1	313	319	PF00069	0.574
MOD_CK1_1	395	401	PF00069	0.689
MOD_CK1_1	434	440	PF00069	0.456
MOD_CK1_1	515	521	PF00069	0.421
MOD_CK1_1	563	569	PF00069	0.413
MOD_CK1_1	65	71	PF00069	0.527
MOD_CK1_1	822	828	PF00069	0.554
MOD_CK1_1	927	933	PF00069	0.575
MOD_CK1_1	936	942	PF00069	0.498
MOD_CK2_1	198	204	PF00069	0.546
MOD_CK2_1	242	248	PF00069	0.610
MOD_CK2_1	257	263	PF00069	0.498
MOD_CK2_1	562	568	PF00069	0.453
MOD_CK2_1	617	623	PF00069	0.429
MOD_CK2_1	758	764	PF00069	0.670
MOD_CK2_1	9	15	PF00069	0.524
MOD_Cter_Amidation	445	448	PF01082	0.465
MOD_DYRK1A_RPxSP_1	817	821	PF00069	0.579
MOD_GlcNHglycan	12	15	PF01048	0.544
MOD_GlcNHglycan	126	130	PF01048	0.518
MOD_GlcNHglycan	144	147	PF01048	0.535
MOD_GlcNHglycan	190	193	PF01048	0.556
MOD_GlcNHglycan	239	242	PF01048	0.537
MOD_GlcNHglycan	305	308	PF01048	0.550
MOD_GlcNHglycan	315	318	PF01048	0.579
MOD_GlcNHglycan	34	37	PF01048	0.551
MOD_GlcNHglycan	360	363	PF01048	0.493
MOD_GlcNHglycan	394	397	PF01048	0.749
MOD_GlcNHglycan	404	408	PF01048	0.456
MOD_GlcNHglycan	51	54	PF01048	0.673
MOD_GlcNHglycan	514	517	PF01048	0.477
MOD_GlcNHglycan	545	548	PF01048	0.466
MOD_GlcNHglycan	562	565	PF01048	0.453
MOD_GlcNHglycan	57	61	PF01048	0.524
MOD_GlcNHglycan	610	613	PF01048	0.506
MOD_GlcNHglycan	63	67	PF01048	0.516
MOD_GlcNHglycan	655	659	PF01048	0.694
MOD_GlcNHglycan	672	675	PF01048	0.396
MOD_GlcNHglycan	754	757	PF01048	0.544
MOD_GlcNHglycan	759	763	PF01048	0.507
MOD_GlcNHglycan	788	791	PF01048	0.590
MOD_GlcNHglycan	797	800	PF01048	0.681
MOD_GlcNHglycan	804	807	PF01048	0.534
MOD_GlcNHglycan	852	855	PF01048	0.614
MOD_GlcNHglycan	859	862	PF01048	0.622
MOD_GlcNHglycan	872	875	PF01048	0.473
MOD_GlcNHglycan	926	929	PF01048	0.572
MOD_GlcNHglycan	93	96	PF01048	0.549
MOD_GlcNHglycan	935	938	PF01048	0.483
MOD_GSK3_1	120	127	PF00069	0.595
MOD_GSK3_1	136	143	PF00069	0.527
MOD_GSK3_1	233	240	PF00069	0.610
MOD_GSK3_1	24	31	PF00069	0.736
MOD_GSK3_1	242	249	PF00069	0.534
MOD_GSK3_1	299	306	PF00069	0.595
MOD_GSK3_1	377	384	PF00069	0.516
MOD_GSK3_1	427	434	PF00069	0.558
MOD_GSK3_1	51	58	PF00069	0.543
MOD_GSK3_1	533	540	PF00069	0.481
MOD_GSK3_1	559	566	PF00069	0.459
MOD_GSK3_1	615	622	PF00069	0.516
MOD_GSK3_1	65	72	PF00069	0.511
MOD_GSK3_1	768	775	PF00069	0.544
MOD_GSK3_1	791	798	PF00069	0.595
MOD_GSK3_1	802	809	PF00069	0.577
MOD_GSK3_1	815	822	PF00069	0.584
MOD_GSK3_1	839	846	PF00069	0.596
MOD_GSK3_1	857	864	PF00069	0.569
MOD_GSK3_1	916	923	PF00069	0.542
MOD_GSK3_1	924	931	PF00069	0.595
MOD_GSK3_1	998	1005	PF00069	0.435
MOD_N-GLC_1	103	108	PF02516	0.510
MOD_N-GLC_1	69	74	PF02516	0.523
MOD_N-GLC_1	843	848	PF02516	0.567
MOD_NEK2_1	103	108	PF00069	0.543
MOD_NEK2_1	18	23	PF00069	0.495
MOD_NEK2_1	883	888	PF00069	0.518
MOD_NEK2_1	9	14	PF00069	0.673
MOD_NEK2_1	970	975	PF00069	0.390
MOD_NEK2_1	998	1003	PF00069	0.438
MOD_NEK2_2	324	329	PF00069	0.450
MOD_NEK2_2	377	382	PF00069	0.564
MOD_NEK2_2	916	921	PF00069	0.520
MOD_PIKK_1	166	172	PF00454	0.494
MOD_PIKK_1	227	233	PF00454	0.537
MOD_PIKK_1	299	305	PF00454	0.551
MOD_PIKK_1	539	545	PF00454	0.484
MOD_PIKK_1	700	706	PF00454	0.431
MOD_PIKK_1	928	934	PF00454	0.564
MOD_PIKK_1	949	955	PF00454	0.516
MOD_PKA_1	358	364	PF00069	0.380
MOD_PKA_1	752	758	PF00069	0.477
MOD_PKA_2	120	126	PF00069	0.565
MOD_PKA_2	140	146	PF00069	0.495
MOD_PKA_2	166	172	PF00069	0.519
MOD_PKA_2	303	309	PF00069	0.576
MOD_PKA_2	341	347	PF00069	0.585
MOD_PKA_2	358	364	PF00069	0.353
MOD_PKA_2	381	387	PF00069	0.451
MOD_PKA_2	431	437	PF00069	0.491
MOD_PKA_2	533	539	PF00069	0.482
MOD_PKA_2	752	758	PF00069	0.477
MOD_PKA_2	791	797	PF00069	0.572
MOD_PKA_2	801	807	PF00069	0.567
MOD_PKA_2	837	843	PF00069	0.559
MOD_PKA_2	857	863	PF00069	0.519
MOD_PKA_2	970	976	PF00069	0.441
MOD_PKB_1	47	55	PF00069	0.547
MOD_Plk_1	131	137	PF00069	0.573
MOD_Plk_1	206	212	PF00069	0.683
MOD_Plk_1	377	383	PF00069	0.514
MOD_Plk_1	622	628	PF00069	0.374
MOD_Plk_1	638	644	PF00069	0.414
MOD_Plk_1	69	75	PF00069	0.510
MOD_Plk_1	832	838	PF00069	0.577
MOD_Plk_2-3	494	500	PF00069	0.400
MOD_Plk_2-3	712	718	PF00069	0.446
MOD_Plk_4	638	644	PF00069	0.414
MOD_Plk_4	70	76	PF00069	0.508
MOD_ProDKin_1	182	188	PF00069	0.554
MOD_ProDKin_1	198	204	PF00069	0.536
MOD_ProDKin_1	233	239	PF00069	0.516
MOD_ProDKin_1	310	316	PF00069	0.537
MOD_ProDKin_1	383	389	PF00069	0.481
MOD_ProDKin_1	427	433	PF00069	0.556
MOD_ProDKin_1	475	481	PF00069	0.516
MOD_ProDKin_1	537	543	PF00069	0.483
MOD_ProDKin_1	615	621	PF00069	0.451
MOD_ProDKin_1	781	787	PF00069	0.639
MOD_ProDKin_1	797	803	PF00069	0.518
MOD_ProDKin_1	817	823	PF00069	0.513
MOD_ProDKin_1	861	867	PF00069	0.592
MOD_ProDKin_1	920	926	PF00069	0.609
MOD_ProDKin_1	939	945	PF00069	0.564
MOD_SUMO_for_1	362	365	PF00179	0.461
MOD_SUMO_for_1	369	372	PF00179	0.439
TRG_DiLeu_BaEn_1	470	475	PF01217	0.421
TRG_DiLeu_BaEn_1	994	999	PF01217	0.416
TRG_DiLeu_BaEn_4	711	717	PF01217	0.463
TRG_DiLeu_LyEn_5	994	999	PF01217	0.416
TRG_ENDOCYTIC_2	74	77	PF00928	0.502
TRG_ER_diArg_1	151	154	PF00400	0.575
TRG_ER_diArg_1	187	190	PF00400	0.526
TRG_ER_diArg_1	216	218	PF00400	0.558
TRG_ER_diArg_1	357	359	PF00400	0.397
TRG_ER_diArg_1	387	390	PF00400	0.489
TRG_ER_diArg_1	445	448	PF00400	0.465
TRG_ER_diArg_1	47	50	PF00400	0.551
TRG_ER_diArg_1	522	524	PF00400	0.485
TRG_ER_diArg_1	614	616	PF00400	0.403
TRG_ER_diArg_1	647	650	PF00400	0.411
TRG_ER_diArg_1	725	728	PF00400	0.525
TRG_NES_CRM1_1	408	421	PF08389	0.516
TRG_NLS_MonoExtC_3	723	728	PF00514	0.388
TRG_NLS_MonoExtN_4	721	728	PF00514	0.384
TRG_Pf-PMV_PEXEL_1	115	120	PF00026	0.525
TRG_Pf-PMV_PEXEL_1	217	221	PF00026	0.559
TRG_Pf-PMV_PEXEL_1	522	527	PF00026	0.496
TRG_Pf-PMV_PEXEL_1	529	533	PF00026	0.463
TRG_Pf-PMV_PEXEL_1	910	915	PF00026	0.444
TRG_Pf-PMV_PEXEL_1	948	953	PF00026	0.495
TRG_Pf-PMV_PEXEL_1	990	994	PF00026	0.506

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HRK6	Leptomonas seymouri	44%	100%
A4HLC7	Leishmania braziliensis	65%	99%
E9AVI1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%