BAR domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HZG4_LEIIN

TriTrypDb:

LINF_210025600

Length:

241

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HZG4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HZG4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	92	96	PF00656	0.622
CLV_NRD_NRD_1	129	131	PF00675	0.664
CLV_NRD_NRD_1	220	222	PF00675	0.625
CLV_PCSK_KEX2_1	168	170	PF00082	0.635
CLV_PCSK_PC1ET2_1	168	170	PF00082	0.635
CLV_PCSK_SKI1_1	122	126	PF00082	0.671
CLV_PCSK_SKI1_1	43	47	PF00082	0.637
DEG_Nend_UBRbox_1	1	4	PF02207	0.790
DOC_CKS1_1	231	236	PF01111	0.710
DOC_CYCLIN_yCln2_LP_2	228	234	PF00134	0.578
DOC_MAPK_gen_1	133	141	PF00069	0.600
DOC_MAPK_gen_1	17	25	PF00069	0.719
DOC_SPAK_OSR1_1	193	197	PF12202	0.526
DOC_USP7_MATH_1	140	144	PF00917	0.457
DOC_USP7_MATH_1	30	34	PF00917	0.592
DOC_USP7_MATH_1	85	89	PF00917	0.491
DOC_USP7_UBL2_3	147	151	PF12436	0.612
DOC_USP7_UBL2_3	36	40	PF12436	0.652
DOC_USP7_UBL2_3	43	47	PF12436	0.521
DOC_WW_Pin1_4	230	235	PF00397	0.541
DOC_WW_Pin1_4	24	29	PF00397	0.707
LIG_14-3-3_CanoR_1	211	220	PF00244	0.604
LIG_Actin_WH2_2	110	127	PF00022	0.648
LIG_AP2alpha_1	183	187	PF02296	0.606
LIG_APCC_ABBA_1	196	201	PF00400	0.530
LIG_BRCT_BRCA1_1	110	114	PF00533	0.627
LIG_BRCT_BRCA1_1	65	69	PF00533	0.491
LIG_FHA_1	55	61	PF00498	0.609
LIG_LIR_Gen_1	184	194	PF02991	0.605
LIG_LIR_Nem_3	111	117	PF02991	0.641
LIG_LIR_Nem_3	184	190	PF02991	0.609
LIG_LIR_Nem_3	191	197	PF02991	0.487
LIG_PCNA_PIPBox_1	202	211	PF02747	0.433
LIG_Pex14_2	183	187	PF04695	0.606
LIG_Pex14_2	190	194	PF04695	0.473
LIG_SH2_STAT5	162	165	PF00017	0.561
LIG_SH3_3	228	234	PF00018	0.528
LIG_SUMO_SIM_par_1	76	83	PF11976	0.630
MOD_CDK_SPK_2	230	235	PF00069	0.617
MOD_CK1_1	109	115	PF00069	0.548
MOD_CK1_1	214	220	PF00069	0.602
MOD_CK2_1	129	135	PF00069	0.656
MOD_CK2_1	85	91	PF00069	0.530
MOD_GlcNHglycan	213	216	PF01048	0.600
MOD_GlcNHglycan	82	85	PF01048	0.608
MOD_GlcNHglycan	87	90	PF01048	0.514
MOD_GSK3_1	24	31	PF00069	0.422
MOD_GSK3_1	50	57	PF00069	0.615
MOD_GSK3_1	9	16	PF00069	0.663
MOD_NEK2_1	106	111	PF00069	0.537
MOD_NEK2_1	13	18	PF00069	0.684
MOD_NEK2_1	161	166	PF00069	0.627
MOD_NEK2_1	79	84	PF00069	0.508
MOD_PIKK_1	140	146	PF00454	0.520
MOD_PIKK_1	163	169	PF00454	0.645
MOD_PKA_2	129	135	PF00069	0.656
MOD_PKA_2	54	60	PF00069	0.538
MOD_Plk_1	106	112	PF00069	0.614
MOD_Plk_1	134	140	PF00069	0.648
MOD_Plk_1	174	180	PF00069	0.482
MOD_Plk_1	28	34	PF00069	0.651
MOD_Plk_4	134	140	PF00069	0.622
MOD_ProDKin_1	230	236	PF00069	0.544
MOD_ProDKin_1	24	30	PF00069	0.700
MOD_SUMO_for_1	156	159	PF00179	0.369
MOD_SUMO_rev_2	119	127	PF00179	0.655
MOD_SUMO_rev_2	153	158	PF00179	0.670
MOD_SUMO_rev_2	200	205	PF00179	0.598
TRG_ENDOCYTIC_2	199	202	PF00928	0.614
TRG_Pf-PMV_PEXEL_1	122	126	PF00026	0.671
TRG_Pf-PMV_PEXEL_1	203	207	PF00026	0.504
TRG_Pf-PMV_PEXEL_1	44	48	PF00026	0.641

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WWW7	Leishmania donovani	99%	100%
A4HC21	Leishmania braziliensis	73%	100%
E9AVF4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
Q4QC25	Leishmania major	93%	100%