LeishMANIAdb
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Exocyst complex component Sec8

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Exocyst complex component Sec8
Gene product:
Protein of unknown function N-terminal domain (DUF2450)/Sec8 exocyst complex component specific domain containing protein - putative
Species:
Leishmania infantum
UniProt:
A4HZG2_LEIIN
TriTrypDb:
LINF_210024000
Length:
2056

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Cellular components
Term Name Level Count
GO:0000145 exocyst 3 9
GO:0032991 protein-containing complex 1 9
GO:0099023 vesicle tethering complex 2 9
GO:0005737 cytoplasm 2 1
GO:0110165 cellular anatomical entity 1 2
GO:0016020 membrane 2 1

Expansion

Sequence features

A4HZG2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HZG2

Function

Biological processes
Term Name Level Count
GO:0006605 protein targeting 5 8
GO:0006612 protein targeting to membrane 5 8
GO:0006810 transport 3 8
GO:0006886 intracellular protein transport 4 8
GO:0006892 post-Golgi vesicle-mediated transport 6 8
GO:0006893 Golgi to plasma membrane transport 5 8
GO:0006904 vesicle docking involved in exocytosis 3 9
GO:0008104 protein localization 4 8
GO:0009987 cellular process 1 9
GO:0015031 protein transport 4 8
GO:0016043 cellular component organization 3 8
GO:0016192 vesicle-mediated transport 4 8
GO:0022406 membrane docking 2 9
GO:0033036 macromolecule localization 2 8
GO:0045184 establishment of protein localization 3 8
GO:0046907 intracellular transport 3 8
GO:0048193 Golgi vesicle transport 5 8
GO:0048278 vesicle docking 4 9
GO:0051179 localization 1 9
GO:0051234 establishment of localization 2 8
GO:0051640 organelle localization 2 9
GO:0051641 cellular localization 2 8
GO:0051649 establishment of localization in cell 3 8
GO:0051668 localization within membrane 3 8
GO:0070727 cellular macromolecule localization 3 8
GO:0071702 organic substance transport 4 8
GO:0071705 nitrogen compound transport 4 8
GO:0071840 cellular component organization or biogenesis 2 8
GO:0072657 protein localization to membrane 4 8
GO:0090150 establishment of protein localization to membrane 4 8
GO:0090522 vesicle tethering involved in exocytosis 3 8
GO:0098876 vesicle-mediated transport to the plasma membrane 4 8
GO:0099022 vesicle tethering 4 8
GO:0140029 exocytic process 2 9
GO:0140056 organelle localization by membrane tethering 3 9
GO:0006887 exocytosis 4 1
GO:0032940 secretion by cell 3 1
GO:0046903 secretion 4 1
GO:0140352 export from cell 2 1
Could not find GO molecular_function term for this entry.

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1223 1227 PF00656 0.666
CLV_C14_Caspase3-7 1418 1422 PF00656 0.727
CLV_C14_Caspase3-7 1798 1802 PF00656 0.836
CLV_C14_Caspase3-7 352 356 PF00656 0.650
CLV_C14_Caspase3-7 407 411 PF00656 0.578
CLV_C14_Caspase3-7 443 447 PF00656 0.559
CLV_C14_Caspase3-7 564 568 PF00656 0.682
CLV_C14_Caspase3-7 977 981 PF00656 0.392
CLV_NRD_NRD_1 1103 1105 PF00675 0.674
CLV_NRD_NRD_1 1153 1155 PF00675 0.486
CLV_NRD_NRD_1 1297 1299 PF00675 0.448
CLV_NRD_NRD_1 1355 1357 PF00675 0.415
CLV_NRD_NRD_1 1474 1476 PF00675 0.472
CLV_NRD_NRD_1 1573 1575 PF00675 0.340
CLV_NRD_NRD_1 1920 1922 PF00675 0.568
CLV_NRD_NRD_1 2023 2025 PF00675 0.529
CLV_NRD_NRD_1 2045 2047 PF00675 0.594
CLV_NRD_NRD_1 29 31 PF00675 0.364
CLV_NRD_NRD_1 642 644 PF00675 0.520
CLV_NRD_NRD_1 716 718 PF00675 0.421
CLV_NRD_NRD_1 967 969 PF00675 0.611
CLV_PCSK_KEX2_1 1153 1155 PF00082 0.486
CLV_PCSK_KEX2_1 1198 1200 PF00082 0.428
CLV_PCSK_KEX2_1 1297 1299 PF00082 0.448
CLV_PCSK_KEX2_1 1325 1327 PF00082 0.381
CLV_PCSK_KEX2_1 1355 1357 PF00082 0.446
CLV_PCSK_KEX2_1 1474 1476 PF00082 0.469
CLV_PCSK_KEX2_1 1573 1575 PF00082 0.340
CLV_PCSK_KEX2_1 1920 1922 PF00082 0.568
CLV_PCSK_KEX2_1 2023 2025 PF00082 0.595
CLV_PCSK_KEX2_1 2045 2047 PF00082 0.559
CLV_PCSK_KEX2_1 715 717 PF00082 0.406
CLV_PCSK_PC1ET2_1 1198 1200 PF00082 0.428
CLV_PCSK_PC1ET2_1 1325 1327 PF00082 0.381
CLV_PCSK_SKI1_1 1048 1052 PF00082 0.649
CLV_PCSK_SKI1_1 1198 1202 PF00082 0.426
CLV_PCSK_SKI1_1 123 127 PF00082 0.519
CLV_PCSK_SKI1_1 1297 1301 PF00082 0.454
CLV_PCSK_SKI1_1 1589 1593 PF00082 0.349
CLV_PCSK_SKI1_1 16 20 PF00082 0.363
CLV_PCSK_SKI1_1 1653 1657 PF00082 0.355
CLV_PCSK_SKI1_1 1663 1667 PF00082 0.318
CLV_PCSK_SKI1_1 1693 1697 PF00082 0.343
CLV_PCSK_SKI1_1 1942 1946 PF00082 0.568
CLV_PCSK_SKI1_1 298 302 PF00082 0.474
CLV_PCSK_SKI1_1 308 312 PF00082 0.435
CLV_PCSK_SKI1_1 31 35 PF00082 0.339
CLV_PCSK_SKI1_1 348 352 PF00082 0.457
CLV_PCSK_SKI1_1 464 468 PF00082 0.301
CLV_PCSK_SKI1_1 489 493 PF00082 0.340
CLV_PCSK_SKI1_1 763 767 PF00082 0.394
CLV_PCSK_SKI1_1 785 789 PF00082 0.356
CLV_PCSK_SKI1_1 957 961 PF00082 0.674
DEG_APCC_DBOX_1 1626 1634 PF00400 0.557
DEG_APCC_DBOX_1 1652 1660 PF00400 0.570
DEG_APCC_DBOX_1 494 502 PF00400 0.565
DEG_APCC_DBOX_1 762 770 PF00400 0.589
DEG_COP1_1 1175 1184 PF00400 0.593
DEG_SCF_TRCP1_1 1226 1231 PF00400 0.700
DEG_SPOP_SBC_1 1246 1250 PF00917 0.714
DEG_SPOP_SBC_1 141 145 PF00917 0.610
DEG_SPOP_SBC_1 1837 1841 PF00917 0.644
DOC_AGCK_PIF_1 73 78 PF00069 0.359
DOC_CDC14_PxL_1 1544 1552 PF14671 0.536
DOC_CKS1_1 1928 1933 PF01111 0.791
DOC_CKS1_1 596 601 PF01111 0.615
DOC_CYCLIN_RxL_1 25 37 PF00134 0.558
DOC_CYCLIN_RxL_1 462 473 PF00134 0.501
DOC_CYCLIN_RxL_1 734 746 PF00134 0.609
DOC_CYCLIN_RxL_1 869 880 PF00134 0.377
DOC_CYCLIN_RxL_1 965 975 PF00134 0.408
DOC_CYCLIN_yClb1_LxF_4 666 672 PF00134 0.552
DOC_CYCLIN_yClb5_NLxxxL_5 301 310 PF00134 0.682
DOC_CYCLIN_yCln2_LP_2 1945 1951 PF00134 0.757
DOC_MAPK_DCC_7 1653 1661 PF00069 0.614
DOC_MAPK_gen_1 1045 1054 PF00069 0.452
DOC_MAPK_gen_1 1625 1632 PF00069 0.561
DOC_MAPK_gen_1 935 942 PF00069 0.443
DOC_MAPK_gen_1 968 974 PF00069 0.412
DOC_MAPK_MEF2A_6 1653 1662 PF00069 0.612
DOC_MAPK_MEF2A_6 1686 1694 PF00069 0.595
DOC_MAPK_MEF2A_6 812 821 PF00069 0.362
DOC_MAPK_MEF2A_6 935 942 PF00069 0.443
DOC_PP1_RVXF_1 1121 1128 PF00149 0.476
DOC_PP1_RVXF_1 1324 1331 PF00149 0.607
DOC_PP1_RVXF_1 1538 1545 PF00149 0.577
DOC_PP1_RVXF_1 1655 1662 PF00149 0.560
DOC_PP1_RVXF_1 1691 1697 PF00149 0.560
DOC_PP1_RVXF_1 28 35 PF00149 0.560
DOC_PP1_RVXF_1 870 877 PF00149 0.390
DOC_PP2B_LxvP_1 1545 1548 PF13499 0.589
DOC_PP2B_LxvP_1 1639 1642 PF13499 0.554
DOC_PP2B_LxvP_1 1743 1746 PF13499 0.614
DOC_PP2B_LxvP_1 1830 1833 PF13499 0.619
DOC_PP2B_PxIxI_1 5 11 PF00149 0.552
DOC_PP4_FxxP_1 1655 1658 PF00568 0.528
DOC_PP4_FxxP_1 794 797 PF00568 0.402
DOC_USP7_MATH_1 1020 1024 PF00917 0.468
DOC_USP7_MATH_1 1211 1215 PF00917 0.608
DOC_USP7_MATH_1 1235 1239 PF00917 0.782
DOC_USP7_MATH_1 1291 1295 PF00917 0.600
DOC_USP7_MATH_1 141 145 PF00917 0.729
DOC_USP7_MATH_1 1559 1563 PF00917 0.649
DOC_USP7_MATH_1 1642 1646 PF00917 0.600
DOC_USP7_MATH_1 172 176 PF00917 0.664
DOC_USP7_MATH_1 1799 1803 PF00917 0.805
DOC_USP7_MATH_1 1808 1812 PF00917 0.828
DOC_USP7_MATH_1 1825 1829 PF00917 0.761
DOC_USP7_MATH_1 1853 1857 PF00917 0.745
DOC_USP7_MATH_1 1873 1877 PF00917 0.684
DOC_USP7_MATH_1 1897 1901 PF00917 0.775
DOC_USP7_MATH_1 1913 1917 PF00917 0.828
DOC_USP7_MATH_1 2047 2051 PF00917 0.818
DOC_USP7_MATH_1 254 258 PF00917 0.739
DOC_USP7_MATH_1 296 300 PF00917 0.672
DOC_USP7_MATH_1 44 48 PF00917 0.552
DOC_USP7_MATH_1 447 451 PF00917 0.501
DOC_USP7_MATH_1 465 469 PF00917 0.501
DOC_USP7_MATH_1 579 583 PF00917 0.735
DOC_USP7_MATH_1 629 633 PF00917 0.719
DOC_USP7_MATH_1 696 700 PF00917 0.551
DOC_USP7_MATH_1 846 850 PF00917 0.523
DOC_WW_Pin1_4 1233 1238 PF00397 0.787
DOC_WW_Pin1_4 1412 1417 PF00397 0.767
DOC_WW_Pin1_4 142 147 PF00397 0.753
DOC_WW_Pin1_4 1823 1828 PF00397 0.767
DOC_WW_Pin1_4 1869 1874 PF00397 0.792
DOC_WW_Pin1_4 1927 1932 PF00397 0.782
DOC_WW_Pin1_4 1953 1958 PF00397 0.744
DOC_WW_Pin1_4 2032 2037 PF00397 0.771
DOC_WW_Pin1_4 380 385 PF00397 0.731
DOC_WW_Pin1_4 595 600 PF00397 0.607
DOC_WW_Pin1_4 793 798 PF00397 0.446
DOC_WW_Pin1_4 8 13 PF00397 0.553
DOC_WW_Pin1_4 850 855 PF00397 0.444
DOC_WW_Pin1_4 903 908 PF00397 0.480
DOC_WW_Pin1_4 914 919 PF00397 0.566
DOC_WW_Pin1_4 925 930 PF00397 0.501
LIG_14-3-3_CanoR_1 1045 1054 PF00244 0.424
LIG_14-3-3_CanoR_1 1068 1074 PF00244 0.541
LIG_14-3-3_CanoR_1 1109 1117 PF00244 0.500
LIG_14-3-3_CanoR_1 1185 1194 PF00244 0.622
LIG_14-3-3_CanoR_1 1202 1206 PF00244 0.628
LIG_14-3-3_CanoR_1 1396 1402 PF00244 0.719
LIG_14-3-3_CanoR_1 1478 1486 PF00244 0.610
LIG_14-3-3_CanoR_1 1495 1503 PF00244 0.613
LIG_14-3-3_CanoR_1 1523 1528 PF00244 0.566
LIG_14-3-3_CanoR_1 1625 1633 PF00244 0.592
LIG_14-3-3_CanoR_1 1814 1823 PF00244 0.767
LIG_14-3-3_CanoR_1 2046 2055 PF00244 0.795
LIG_14-3-3_CanoR_1 464 470 PF00244 0.525
LIG_14-3-3_CanoR_1 509 519 PF00244 0.608
LIG_14-3-3_CanoR_1 520 526 PF00244 0.558
LIG_14-3-3_CanoR_1 646 655 PF00244 0.627
LIG_14-3-3_CanoR_1 695 701 PF00244 0.572
LIG_14-3-3_CanoR_1 719 725 PF00244 0.689
LIG_Actin_WH2_2 1538 1553 PF00022 0.588
LIG_Actin_WH2_2 1644 1659 PF00022 0.600
LIG_Actin_WH2_2 1705 1722 PF00022 0.614
LIG_Actin_WH2_2 512 528 PF00022 0.641
LIG_Actin_WH2_2 762 780 PF00022 0.595
LIG_Actin_WH2_2 963 981 PF00022 0.407
LIG_AP2alpha_1 1345 1349 PF02296 0.580
LIG_BIR_III_2 926 930 PF00653 0.410
LIG_BRCT_BRCA1_1 10 14 PF00533 0.554
LIG_BRCT_BRCA1_1 143 147 PF00533 0.674
LIG_BRCT_BRCA1_1 1651 1655 PF00533 0.544
LIG_BRCT_BRCA1_1 1786 1790 PF00533 0.720
LIG_BRCT_BRCA1_1 187 191 PF00533 0.752
LIG_BRCT_BRCA1_1 2049 2053 PF00533 0.816
LIG_BRCT_BRCA1_1 263 267 PF00533 0.690
LIG_Clathr_ClatBox_1 1605 1609 PF01394 0.552
LIG_Clathr_ClatBox_1 747 751 PF01394 0.656
LIG_deltaCOP1_diTrp_1 996 1003 PF00928 0.441
LIG_eIF4E_1 1073 1079 PF01652 0.468
LIG_FHA_1 1047 1053 PF00498 0.465
LIG_FHA_1 1061 1067 PF00498 0.516
LIG_FHA_1 1083 1089 PF00498 0.501
LIG_FHA_1 1267 1273 PF00498 0.643
LIG_FHA_1 1303 1309 PF00498 0.621
LIG_FHA_1 1396 1402 PF00498 0.709
LIG_FHA_1 1498 1504 PF00498 0.725
LIG_FHA_1 1626 1632 PF00498 0.572
LIG_FHA_1 1634 1640 PF00498 0.584
LIG_FHA_1 1683 1689 PF00498 0.637
LIG_FHA_1 1704 1710 PF00498 0.597
LIG_FHA_1 1928 1934 PF00498 0.684
LIG_FHA_1 1970 1976 PF00498 0.805
LIG_FHA_1 24 30 PF00498 0.554
LIG_FHA_1 345 351 PF00498 0.620
LIG_FHA_1 63 69 PF00498 0.440
LIG_FHA_1 633 639 PF00498 0.736
LIG_FHA_1 830 836 PF00498 0.410
LIG_FHA_1 903 909 PF00498 0.583
LIG_FHA_1 954 960 PF00498 0.395
LIG_FHA_2 1062 1068 PF00498 0.475
LIG_FHA_2 1163 1169 PF00498 0.534
LIG_FHA_2 1455 1461 PF00498 0.585
LIG_FHA_2 1641 1647 PF00498 0.555
LIG_FHA_2 376 382 PF00498 0.709
LIG_FHA_2 522 528 PF00498 0.605
LIG_FHA_2 652 658 PF00498 0.644
LIG_FHA_2 67 73 PF00498 0.359
LIG_FHA_2 769 775 PF00498 0.554
LIG_FHA_2 831 837 PF00498 0.397
LIG_GBD_Chelix_1 1670 1678 PF00786 0.397
LIG_GBD_Chelix_1 302 310 PF00786 0.433
LIG_HP1_1 1143 1147 PF01393 0.490
LIG_IRF3_LxIS_1 970 975 PF10401 0.263
LIG_LIR_Apic_2 1652 1658 PF02991 0.582
LIG_LIR_Gen_1 1011 1020 PF02991 0.402
LIG_LIR_Gen_1 1087 1096 PF02991 0.457
LIG_LIR_Gen_1 1112 1122 PF02991 0.510
LIG_LIR_Gen_1 1500 1509 PF02991 0.670
LIG_LIR_Gen_1 1538 1548 PF02991 0.521
LIG_LIR_Gen_1 1552 1563 PF02991 0.582
LIG_LIR_Gen_1 1677 1688 PF02991 0.607
LIG_LIR_Gen_1 349 359 PF02991 0.721
LIG_LIR_Gen_1 422 430 PF02991 0.559
LIG_LIR_Gen_1 666 676 PF02991 0.581
LIG_LIR_Gen_1 72 81 PF02991 0.561
LIG_LIR_Gen_1 811 821 PF02991 0.432
LIG_LIR_Gen_1 928 938 PF02991 0.556
LIG_LIR_LC3C_4 1319 1322 PF02991 0.609
LIG_LIR_Nem_3 1011 1017 PF02991 0.363
LIG_LIR_Nem_3 1087 1093 PF02991 0.468
LIG_LIR_Nem_3 1183 1187 PF02991 0.589
LIG_LIR_Nem_3 1264 1270 PF02991 0.674
LIG_LIR_Nem_3 1376 1381 PF02991 0.563
LIG_LIR_Nem_3 1500 1505 PF02991 0.672
LIG_LIR_Nem_3 1538 1544 PF02991 0.516
LIG_LIR_Nem_3 1552 1558 PF02991 0.575
LIG_LIR_Nem_3 1677 1683 PF02991 0.568
LIG_LIR_Nem_3 175 180 PF02991 0.639
LIG_LIR_Nem_3 264 270 PF02991 0.692
LIG_LIR_Nem_3 349 354 PF02991 0.687
LIG_LIR_Nem_3 393 397 PF02991 0.559
LIG_LIR_Nem_3 662 668 PF02991 0.592
LIG_LIR_Nem_3 72 78 PF02991 0.562
LIG_LIR_Nem_3 928 933 PF02991 0.569
LIG_MAD2 785 793 PF02301 0.438
LIG_MLH1_MIPbox_1 1651 1655 PF16413 0.569
LIG_MYND_1 1742 1746 PF01753 0.694
LIG_MYND_1 2028 2032 PF01753 0.668
LIG_NRBOX 1065 1071 PF00104 0.488
LIG_NRBOX 1216 1222 PF00104 0.670
LIG_PCNA_APIM_2 1651 1657 PF02747 0.571
LIG_PCNA_PIPBox_1 584 593 PF02747 0.702
LIG_PCNA_yPIPBox_3 395 409 PF02747 0.596
LIG_PCNA_yPIPBox_3 584 592 PF02747 0.700
LIG_Pex14_2 1196 1200 PF04695 0.583
LIG_Pex14_2 1345 1349 PF04695 0.556
LIG_Pex14_2 703 707 PF04695 0.594
LIG_Pex14_2 75 79 PF04695 0.447
LIG_Pex14_2 794 798 PF04695 0.458
LIG_Pex14_2 873 877 PF04695 0.404
LIG_PTB_Apo_2 1721 1728 PF02174 0.602
LIG_PTB_Apo_2 491 498 PF02174 0.641
LIG_PTB_Apo_2 776 783 PF02174 0.555
LIG_PTB_Phospho_1 1721 1727 PF10480 0.597
LIG_PTB_Phospho_1 491 497 PF10480 0.644
LIG_PTB_Phospho_1 776 782 PF10480 0.526
LIG_Rb_LxCxE_1 1159 1179 PF01857 0.580
LIG_REV1ctd_RIR_1 1194 1203 PF16727 0.621
LIG_REV1ctd_RIR_1 1652 1657 PF16727 0.575
LIG_REV1ctd_RIR_1 1712 1722 PF16727 0.594
LIG_REV1ctd_RIR_1 690 699 PF16727 0.576
LIG_SH2_CRK 1555 1559 PF00017 0.587
LIG_SH2_CRK 1579 1583 PF00017 0.589
LIG_SH2_CRK 1593 1597 PF00017 0.586
LIG_SH2_CRK 1716 1720 PF00017 0.590
LIG_SH2_GRB2like 1680 1683 PF00017 0.605
LIG_SH2_NCK_1 1167 1171 PF00017 0.583
LIG_SH2_NCK_1 1555 1559 PF00017 0.587
LIG_SH2_NCK_1 726 730 PF00017 0.546
LIG_SH2_SRC 1792 1795 PF00017 0.825
LIG_SH2_SRC 227 230 PF00017 0.723
LIG_SH2_SRC 408 411 PF00017 0.525
LIG_SH2_SRC 726 729 PF00017 0.555
LIG_SH2_STAP1 1167 1171 PF00017 0.583
LIG_SH2_STAP1 1555 1559 PF00017 0.645
LIG_SH2_STAP1 1571 1575 PF00017 0.590
LIG_SH2_STAP1 64 68 PF00017 0.440
LIG_SH2_STAT3 1285 1288 PF00017 0.542
LIG_SH2_STAT3 1372 1375 PF00017 0.643
LIG_SH2_STAT3 1509 1512 PF00017 0.639
LIG_SH2_STAT5 1205 1208 PF00017 0.597
LIG_SH2_STAT5 1285 1288 PF00017 0.550
LIG_SH2_STAT5 1372 1375 PF00017 0.632
LIG_SH2_STAT5 1469 1472 PF00017 0.612
LIG_SH2_STAT5 1480 1483 PF00017 0.618
LIG_SH2_STAT5 1488 1491 PF00017 0.600
LIG_SH2_STAT5 1509 1512 PF00017 0.608
LIG_SH2_STAT5 1593 1596 PF00017 0.536
LIG_SH2_STAT5 1664 1667 PF00017 0.527
LIG_SH2_STAT5 1680 1683 PF00017 0.611
LIG_SH2_STAT5 408 411 PF00017 0.525
LIG_SH2_STAT5 497 500 PF00017 0.527
LIG_SH2_STAT5 64 67 PF00017 0.440
LIG_SH2_STAT5 668 671 PF00017 0.571
LIG_SH2_STAT5 782 785 PF00017 0.527
LIG_SH3_1 1883 1889 PF00018 0.687
LIG_SH3_3 1272 1278 PF00018 0.686
LIG_SH3_3 1736 1742 PF00018 0.715
LIG_SH3_3 1760 1766 PF00018 0.611
LIG_SH3_3 1802 1808 PF00018 0.795
LIG_SH3_3 1883 1889 PF00018 0.707
LIG_SH3_3 1925 1931 PF00018 0.763
LIG_SH3_3 1945 1951 PF00018 0.734
LIG_SH3_3 2022 2028 PF00018 0.823
LIG_SH3_3 208 214 PF00018 0.633
LIG_SH3_3 593 599 PF00018 0.712
LIG_SH3_3 635 641 PF00018 0.791
LIG_SH3_3 796 802 PF00018 0.490
LIG_Sin3_3 1142 1149 PF02671 0.446
LIG_SUMO_SIM_anti_2 1025 1035 PF11976 0.520
LIG_SUMO_SIM_anti_2 1397 1403 PF11976 0.703
LIG_SUMO_SIM_anti_2 1603 1609 PF11976 0.586
LIG_SUMO_SIM_anti_2 1628 1636 PF11976 0.591
LIG_SUMO_SIM_anti_2 1687 1692 PF11976 0.586
LIG_SUMO_SIM_anti_2 200 206 PF11976 0.622
LIG_SUMO_SIM_anti_2 678 683 PF11976 0.583
LIG_SUMO_SIM_par_1 1049 1057 PF11976 0.466
LIG_SUMO_SIM_par_1 105 111 PF11976 0.321
LIG_SUMO_SIM_par_1 1268 1274 PF11976 0.690
LIG_SUMO_SIM_par_1 1397 1403 PF11976 0.735
LIG_SUMO_SIM_par_1 1556 1562 PF11976 0.657
LIG_SUMO_SIM_par_1 1740 1747 PF11976 0.618
LIG_SUMO_SIM_par_1 424 431 PF11976 0.503
LIG_SUMO_SIM_par_1 446 453 PF11976 0.534
LIG_SUMO_SIM_par_1 50 56 PF11976 0.206
LIG_SUMO_SIM_par_1 59 65 PF11976 0.193
LIG_SUMO_SIM_par_1 79 84 PF11976 0.367
LIG_SxIP_EBH_1 1198 1212 PF03271 0.603
LIG_TRAF2_1 1188 1191 PF00917 0.626
LIG_TRAF2_1 1856 1859 PF00917 0.745
LIG_TRAF2_1 1980 1983 PF00917 0.756
LIG_TRFH_1 1654 1658 PF08558 0.457
LIG_TYR_ITIM 1553 1558 PF00017 0.547
LIG_TYR_ITIM 1591 1596 PF00017 0.428
LIG_TYR_ITIM 392 397 PF00017 0.359
LIG_UBA3_1 1033 1040 PF00899 0.614
LIG_UBA3_1 1316 1325 PF00899 0.418
LIG_UBA3_1 679 684 PF00899 0.498
LIG_UBA3_1 769 775 PF00899 0.431
LIG_WRC_WIRS_1 63 68 PF05994 0.448
LIG_WRC_WIRS_1 747 752 PF05994 0.568
LIG_WRC_WIRS_1 75 80 PF05994 0.429
LIG_WW_2 1805 1808 PF00397 0.769
MOD_CDK_SPK_2 850 855 PF00069 0.513
MOD_CDK_SPxK_1 1953 1959 PF00069 0.570
MOD_CK1_1 118 124 PF00069 0.677
MOD_CK1_1 1227 1233 PF00069 0.655
MOD_CK1_1 1248 1254 PF00069 0.674
MOD_CK1_1 1397 1403 PF00069 0.684
MOD_CK1_1 1412 1418 PF00069 0.469
MOD_CK1_1 1497 1503 PF00069 0.621
MOD_CK1_1 1737 1743 PF00069 0.731
MOD_CK1_1 1797 1803 PF00069 0.813
MOD_CK1_1 1810 1816 PF00069 0.679
MOD_CK1_1 183 189 PF00069 0.634
MOD_CK1_1 1899 1905 PF00069 0.806
MOD_CK1_1 2048 2054 PF00069 0.710
MOD_CK1_1 318 324 PF00069 0.673
MOD_CK1_1 375 381 PF00069 0.684
MOD_CK1_1 433 439 PF00069 0.438
MOD_CK1_1 450 456 PF00069 0.438
MOD_CK1_1 632 638 PF00069 0.707
MOD_CK1_1 694 700 PF00069 0.392
MOD_CK1_1 720 726 PF00069 0.611
MOD_CK1_1 849 855 PF00069 0.678
MOD_CK1_1 925 931 PF00069 0.691
MOD_CK2_1 1020 1026 PF00069 0.584
MOD_CK2_1 1162 1168 PF00069 0.406
MOD_CK2_1 1185 1191 PF00069 0.522
MOD_CK2_1 1387 1393 PF00069 0.637
MOD_CK2_1 1397 1403 PF00069 0.637
MOD_CK2_1 1454 1460 PF00069 0.469
MOD_CK2_1 1681 1687 PF00069 0.466
MOD_CK2_1 1853 1859 PF00069 0.712
MOD_CK2_1 1977 1983 PF00069 0.755
MOD_CK2_1 1995 2001 PF00069 0.600
MOD_CK2_1 276 282 PF00069 0.675
MOD_CK2_1 375 381 PF00069 0.594
MOD_CK2_1 722 728 PF00069 0.639
MOD_CK2_1 746 752 PF00069 0.493
MOD_CK2_1 768 774 PF00069 0.437
MOD_GlcNHglycan 1074 1077 PF01048 0.594
MOD_GlcNHglycan 1129 1132 PF01048 0.660
MOD_GlcNHglycan 117 120 PF01048 0.592
MOD_GlcNHglycan 1226 1229 PF01048 0.679
MOD_GlcNHglycan 1230 1233 PF01048 0.756
MOD_GlcNHglycan 1237 1240 PF01048 0.682
MOD_GlcNHglycan 1252 1255 PF01048 0.788
MOD_GlcNHglycan 1263 1266 PF01048 0.636
MOD_GlcNHglycan 1349 1352 PF01048 0.546
MOD_GlcNHglycan 1389 1392 PF01048 0.611
MOD_GlcNHglycan 1411 1414 PF01048 0.645
MOD_GlcNHglycan 1457 1460 PF01048 0.441
MOD_GlcNHglycan 1517 1520 PF01048 0.468
MOD_GlcNHglycan 1561 1564 PF01048 0.531
MOD_GlcNHglycan 1699 1702 PF01048 0.575
MOD_GlcNHglycan 1786 1789 PF01048 0.758
MOD_GlcNHglycan 1810 1813 PF01048 0.815
MOD_GlcNHglycan 1817 1820 PF01048 0.722
MOD_GlcNHglycan 182 185 PF01048 0.745
MOD_GlcNHglycan 1840 1843 PF01048 0.773
MOD_GlcNHglycan 187 190 PF01048 0.691
MOD_GlcNHglycan 1901 1904 PF01048 0.743
MOD_GlcNHglycan 193 196 PF01048 0.713
MOD_GlcNHglycan 1936 1939 PF01048 0.787
MOD_GlcNHglycan 2047 2050 PF01048 0.778
MOD_GlcNHglycan 256 259 PF01048 0.704
MOD_GlcNHglycan 278 281 PF01048 0.727
MOD_GlcNHglycan 288 291 PF01048 0.726
MOD_GlcNHglycan 298 301 PF01048 0.620
MOD_GlcNHglycan 317 320 PF01048 0.495
MOD_GlcNHglycan 336 339 PF01048 0.648
MOD_GlcNHglycan 430 433 PF01048 0.390
MOD_GlcNHglycan 600 603 PF01048 0.779
MOD_GlcNHglycan 648 651 PF01048 0.534
MOD_GlcNHglycan 719 722 PF01048 0.583
MOD_GlcNHglycan 912 915 PF01048 0.785
MOD_GlcNHglycan 950 953 PF01048 0.488
MOD_GlcNHglycan 974 977 PF01048 0.488
MOD_GSK3_1 1020 1027 PF00069 0.610
MOD_GSK3_1 1068 1075 PF00069 0.634
MOD_GSK3_1 1082 1089 PF00069 0.524
MOD_GSK3_1 1201 1208 PF00069 0.490
MOD_GSK3_1 1220 1227 PF00069 0.367
MOD_GSK3_1 1233 1240 PF00069 0.675
MOD_GSK3_1 1246 1253 PF00069 0.721
MOD_GSK3_1 1382 1389 PF00069 0.576
MOD_GSK3_1 1408 1415 PF00069 0.701
MOD_GSK3_1 141 148 PF00069 0.639
MOD_GSK3_1 1494 1501 PF00069 0.592
MOD_GSK3_1 1729 1736 PF00069 0.619
MOD_GSK3_1 1784 1791 PF00069 0.688
MOD_GSK3_1 1808 1815 PF00069 0.694
MOD_GSK3_1 1832 1839 PF00069 0.724
MOD_GSK3_1 1869 1876 PF00069 0.827
MOD_GSK3_1 1909 1916 PF00069 0.803
MOD_GSK3_1 1923 1930 PF00069 0.665
MOD_GSK3_1 21 28 PF00069 0.430
MOD_GSK3_1 521 528 PF00069 0.604
MOD_GSK3_1 566 573 PF00069 0.668
MOD_GSK3_1 579 586 PF00069 0.525
MOD_GSK3_1 62 69 PF00069 0.461
MOD_GSK3_1 621 628 PF00069 0.714
MOD_GSK3_1 846 853 PF00069 0.678
MOD_GSK3_1 910 917 PF00069 0.687
MOD_N-GLC_1 1310 1315 PF02516 0.485
MOD_N-GLC_1 1394 1399 PF02516 0.657
MOD_N-GLC_1 1478 1483 PF02516 0.541
MOD_N-GLC_1 1681 1686 PF02516 0.518
MOD_N-GLC_1 1729 1734 PF02516 0.650
MOD_N-GLC_1 304 309 PF02516 0.635
MOD_N-GLC_1 529 534 PF02516 0.457
MOD_N-GLC_1 625 630 PF02516 0.680
MOD_N-GLC_2 1724 1726 PF02516 0.415
MOD_NEK2_1 1069 1074 PF00069 0.601
MOD_NEK2_1 108 113 PF00069 0.462
MOD_NEK2_1 1127 1132 PF00069 0.623
MOD_NEK2_1 1147 1152 PF00069 0.587
MOD_NEK2_1 1156 1161 PF00069 0.570
MOD_NEK2_1 1201 1206 PF00069 0.446
MOD_NEK2_1 1220 1225 PF00069 0.349
MOD_NEK2_1 1408 1413 PF00069 0.690
MOD_NEK2_1 1454 1459 PF00069 0.444
MOD_NEK2_1 1633 1638 PF00069 0.479
MOD_NEK2_1 1649 1654 PF00069 0.499
MOD_NEK2_1 1681 1686 PF00069 0.570
MOD_NEK2_1 1933 1938 PF00069 0.568
MOD_NEK2_1 428 433 PF00069 0.386
MOD_NEK2_1 525 530 PF00069 0.574
MOD_NEK2_1 66 71 PF00069 0.451
MOD_NEK2_1 827 832 PF00069 0.469
MOD_NEK2_1 910 915 PF00069 0.784
MOD_NEK2_1 933 938 PF00069 0.509
MOD_NEK2_1 948 953 PF00069 0.437
MOD_NEK2_2 44 49 PF00069 0.429
MOD_NEK2_2 465 470 PF00069 0.438
MOD_NEK2_2 521 526 PF00069 0.503
MOD_NEK2_2 688 693 PF00069 0.442
MOD_PIKK_1 1001 1007 PF00454 0.433
MOD_PIKK_1 1020 1026 PF00454 0.584
MOD_PIKK_1 1109 1115 PF00454 0.597
MOD_PIKK_1 1211 1217 PF00454 0.480
MOD_PIKK_1 1616 1622 PF00454 0.536
MOD_PIKK_1 1799 1805 PF00454 0.709
MOD_PKA_1 2045 2051 PF00069 0.673
MOD_PKA_1 715 721 PF00069 0.569
MOD_PKA_2 115 121 PF00069 0.623
MOD_PKA_2 1201 1207 PF00069 0.532
MOD_PKA_2 1332 1338 PF00069 0.441
MOD_PKA_2 1387 1393 PF00069 0.558
MOD_PKA_2 1395 1401 PF00069 0.574
MOD_PKA_2 1494 1500 PF00069 0.583
MOD_PKA_2 1515 1521 PF00069 0.498
MOD_PKA_2 1815 1821 PF00069 0.626
MOD_PKA_2 1891 1897 PF00069 0.725
MOD_PKA_2 2045 2051 PF00069 0.730
MOD_PKA_2 525 531 PF00069 0.519
MOD_PKA_2 570 576 PF00069 0.745
MOD_PKA_2 694 700 PF00069 0.499
MOD_PKA_2 715 721 PF00069 0.569
MOD_PKA_2 733 739 PF00069 0.549
MOD_PKB_1 1107 1115 PF00069 0.444
MOD_PKB_1 715 723 PF00069 0.565
MOD_Plk_1 1061 1067 PF00069 0.633
MOD_Plk_1 1394 1400 PF00069 0.655
MOD_Plk_1 1444 1450 PF00069 0.493
MOD_Plk_1 1497 1503 PF00069 0.539
MOD_Plk_1 1551 1557 PF00069 0.443
MOD_Plk_1 1703 1709 PF00069 0.542
MOD_Plk_1 1909 1915 PF00069 0.724
MOD_Plk_1 243 249 PF00069 0.670
MOD_Plk_1 433 439 PF00069 0.438
MOD_Plk_1 529 535 PF00069 0.491
MOD_Plk_1 644 650 PF00069 0.557
MOD_Plk_2-3 1062 1068 PF00069 0.693
MOD_Plk_2-3 1382 1388 PF00069 0.333
MOD_Plk_2-3 1863 1869 PF00069 0.618
MOD_Plk_2-3 1923 1929 PF00069 0.720
MOD_Plk_2-3 1978 1984 PF00069 0.801
MOD_Plk_2-3 1995 2001 PF00069 0.626
MOD_Plk_2-3 657 663 PF00069 0.582
MOD_Plk_2-3 746 752 PF00069 0.575
MOD_Plk_4 10 16 PF00069 0.434
MOD_Plk_4 1029 1035 PF00069 0.598
MOD_Plk_4 1048 1054 PF00069 0.587
MOD_Plk_4 1147 1153 PF00069 0.607
MOD_Plk_4 1201 1207 PF00069 0.501
MOD_Plk_4 1266 1272 PF00069 0.609
MOD_Plk_4 1397 1403 PF00069 0.684
MOD_Plk_4 1445 1451 PF00069 0.491
MOD_Plk_4 1498 1504 PF00069 0.642
MOD_Plk_4 1734 1740 PF00069 0.665
MOD_Plk_4 1825 1831 PF00069 0.526
MOD_Plk_4 465 471 PF00069 0.438
MOD_Plk_4 583 589 PF00069 0.623
MOD_Plk_4 651 657 PF00069 0.458
MOD_Plk_4 675 681 PF00069 0.455
MOD_Plk_4 688 694 PF00069 0.398
MOD_Plk_4 941 947 PF00069 0.357
MOD_ProDKin_1 1233 1239 PF00069 0.756
MOD_ProDKin_1 1412 1418 PF00069 0.736
MOD_ProDKin_1 142 148 PF00069 0.711
MOD_ProDKin_1 1823 1829 PF00069 0.728
MOD_ProDKin_1 1869 1875 PF00069 0.763
MOD_ProDKin_1 1927 1933 PF00069 0.750
MOD_ProDKin_1 1953 1959 PF00069 0.699
MOD_ProDKin_1 2032 2038 PF00069 0.736
MOD_ProDKin_1 380 386 PF00069 0.675
MOD_ProDKin_1 595 601 PF00069 0.513
MOD_ProDKin_1 793 799 PF00069 0.446
MOD_ProDKin_1 8 14 PF00069 0.432
MOD_ProDKin_1 850 856 PF00069 0.559
MOD_ProDKin_1 903 909 PF00069 0.611
MOD_ProDKin_1 914 920 PF00069 0.725
MOD_ProDKin_1 925 931 PF00069 0.635
MOD_SUMO_for_1 1975 1978 PF00179 0.810
MOD_SUMO_for_1 440 443 PF00179 0.438
MOD_SUMO_for_1 886 889 PF00179 0.638
MOD_SUMO_rev_2 276 286 PF00179 0.699
MOD_SUMO_rev_2 388 397 PF00179 0.438
MOD_SUMO_rev_2 452 461 PF00179 0.438
MOD_SUMO_rev_2 485 491 PF00179 0.440
MOD_SUMO_rev_2 513 519 PF00179 0.524
MOD_SUMO_rev_2 567 576 PF00179 0.716
MOD_SUMO_rev_2 885 895 PF00179 0.579
TRG_DiLeu_BaEn_1 1687 1692 PF01217 0.394
TRG_DiLeu_BaEn_1 487 492 PF01217 0.457
TRG_DiLeu_BaEn_1 989 994 PF01217 0.461
TRG_DiLeu_BaEn_2 1318 1324 PF01217 0.455
TRG_DiLeu_BaLyEn_6 103 108 PF01217 0.227
TRG_DiLeu_BaLyEn_6 1065 1070 PF01217 0.667
TRG_DiLeu_BaLyEn_6 1182 1187 PF01217 0.531
TRG_DiLeu_BaLyEn_6 1336 1341 PF01217 0.506
TRG_DiLeu_BaLyEn_6 1739 1744 PF01217 0.523
TRG_DiLeu_BaLyEn_6 506 511 PF01217 0.540
TRG_ENDOCYTIC_2 1380 1383 PF00928 0.445
TRG_ENDOCYTIC_2 1555 1558 PF00928 0.472
TRG_ENDOCYTIC_2 1579 1582 PF00928 0.454
TRG_ENDOCYTIC_2 1593 1596 PF00928 0.360
TRG_ENDOCYTIC_2 1680 1683 PF00928 0.421
TRG_ENDOCYTIC_2 1716 1719 PF00928 0.475
TRG_ENDOCYTIC_2 394 397 PF00928 0.390
TRG_ENDOCYTIC_2 590 593 PF00928 0.630
TRG_ENDOCYTIC_2 668 671 PF00928 0.454
TRG_ER_diArg_1 1152 1154 PF00400 0.619
TRG_ER_diArg_1 1296 1298 PF00400 0.544
TRG_ER_diArg_1 1355 1357 PF00400 0.505
TRG_ER_diArg_1 1573 1575 PF00400 0.411
TRG_ER_diArg_1 1624 1627 PF00400 0.500
TRG_ER_diArg_1 1883 1886 PF00400 0.574
TRG_ER_diArg_1 1920 1922 PF00400 0.730
TRG_ER_diArg_1 2023 2025 PF00400 0.690
TRG_ER_diArg_1 2044 2046 PF00400 0.728
TRG_ER_diArg_1 461 464 PF00400 0.356
TRG_ER_diArg_1 714 717 PF00400 0.456
TRG_NES_CRM1_1 1005 1019 PF08389 0.433
TRG_NES_CRM1_1 334 349 PF08389 0.640
TRG_NES_CRM1_1 473 487 PF08389 0.402
TRG_NLS_Bipartite_1 1573 1593 PF00514 0.442
TRG_NLS_MonoExtN_4 1472 1479 PF00514 0.444
TRG_Pf-PMV_PEXEL_1 1185 1189 PF00026 0.565
TRG_Pf-PMV_PEXEL_1 1298 1302 PF00026 0.530
TRG_Pf-PMV_PEXEL_1 1371 1375 PF00026 0.490
TRG_Pf-PMV_PEXEL_1 509 514 PF00026 0.551

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IIB9 Leptomonas seymouri 63% 100%
A0A3S7WWU8 Leishmania donovani 99% 100%
A4HC01 Leishmania braziliensis 75% 99%
D0A132 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
E9AVD8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 88% 99%
Q4QC41 Leishmania major 91% 100%
V5BRE7 Trypanosoma cruzi 39% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS