by homology
Contact email: avilan@ula.ve
Publication title: Plasminogen binding proteins in secreted membrane vesicles of Leishmania mexicana
Publication 1st author(s): Figuera
Publication Identifier(s): 23178693
Host organism: -1
Interaction detection method(s): enzymatic linked imunosorbent assay
Interaction type: direct interaction
Identification method participant A: identification by antibody
Identification method participant B: identification by antibody
ID(s) interactor A: E9AUS1
ID(s) interactor B: P00747
Taxid interactor A: Leishmania mexicana
Taxid interactor B: Homo sapiens
Biological role(s) interactor A: unspecified role
Biological role(s) interactor B: unspecified role
Experimental role(s) interactor A: bait
Membrane associated proteins, small myristoylated -1 SMP-1
Source | Evidence on protein | Close homologs |
---|---|---|
Cuervo et al. | no | yes: 0 |
Hassani et al. | no | yes: 2 |
Forrest at al. (metacyclic) | yes | yes: 6 |
Forrest at al. (procyclic) | yes | yes: 8 |
Silverman et al. | no | yes: 1 |
Pissara et al. | yes | yes: 32 |
Source | Evidence on protein | Close homologs |
---|---|---|
Pires et al. | no | yes: 0 |
Source | Evidence on protein | Close homologs |
---|---|---|
Silverman et al. | no | yes: 15 |
Source | Evidence on protein | Close homologs |
---|---|---|
Jamdhade et al. | no | yes: 30 |
Source | Evidence on protein | Close homologs |
---|---|---|
DeepLoc | ||
SignalP6 | no | yes: 0, no: 63 |
NetGPI | no | yes: 0, no: 63 |
Term | Name | Level | Count |
---|---|---|---|
GO:0005654 | nucleoplasm | 2 | 1 |
GO:0005737 | cytoplasm | 2 | 1 |
GO:0031974 | membrane-enclosed lumen | 2 | 1 |
GO:0031981 | nuclear lumen | 5 | 1 |
GO:0032838 | plasma membrane bounded cell projection cytoplasm | 4 | 1 |
GO:0043233 | organelle lumen | 3 | 1 |
GO:0070013 | intracellular organelle lumen | 4 | 1 |
GO:0097014 | ciliary plasm | 5 | 1 |
GO:0097542 | ciliary tip | 2 | 1 |
GO:0099568 | cytoplasmic region | 3 | 1 |
GO:0110165 | cellular anatomical entity | 1 | 3 |
GO:0016020 | membrane | 2 | 2 |
GO:0020018 | ciliary pocket membrane | 6 | 1 |
GO:0031090 | organelle membrane | 3 | 2 |
GO:0031253 | cell projection membrane | 4 | 2 |
GO:0060170 | ciliary membrane | 5 | 2 |
GO:0098588 | bounding membrane of organelle | 4 | 2 |
GO:0098590 | plasma membrane region | 3 | 2 |
Source | Evidence on protein | Close homologs |
---|---|---|
Pescher et al. (upgregulation) | no | yes: 0 |
Source | Evidence on protein | Close homologs |
---|---|---|
Lahav et al. - mRNA
- Protein
|
Term | Name | Level | Count |
---|---|---|---|
GO:0001539 | cilium or flagellum-dependent cell motility | 3 | 1 |
GO:0009987 | cellular process | 1 | 2 |
GO:0048870 | cell motility | 2 | 1 |
GO:0060285 | cilium-dependent cell motility | 4 | 1 |
GO:0006996 | organelle organization | 4 | 1 |
GO:0016043 | cellular component organization | 3 | 1 |
GO:0022607 | cellular component assembly | 4 | 1 |
GO:0030030 | cell projection organization | 4 | 1 |
GO:0030031 | cell projection assembly | 5 | 1 |
GO:0044000 | movement in host | 4 | 1 |
GO:0044403 | biological process involved in symbiotic interaction | 2 | 1 |
GO:0044409 | entry into host | 5 | 1 |
GO:0044419 | biological process involved in interspecies interaction between organisms | 1 | 1 |
GO:0044782 | cilium organization | 5 | 1 |
GO:0051701 | biological process involved in interaction with host | 3 | 1 |
GO:0060271 | cilium assembly | 6 | 1 |
GO:0070925 | organelle assembly | 5 | 1 |
GO:0071840 | cellular component organization or biogenesis | 2 | 1 |
GO:0120031 | plasma membrane bounded cell projection assembly | 6 | 1 |
GO:0120036 | plasma membrane bounded cell projection organization | 5 | 1 |
Term | Name | Level | Count |
---|---|---|---|
GO:0003824 | catalytic activity | 1 | 1 |
GO:0016787 | hydrolase activity | 2 | 1 |
Leishmania | From | To | Domain/Motif | Score |
---|---|---|---|---|
CLV_C14_Caspase3-7 | 111 | 115 | PF00656 | 0.414 |
DOC_MAPK_gen_1 | 110 | 118 | PF00069 | 0.278 |
DOC_USP7_UBL2_3 | 28 | 32 | PF12436 | 0.405 |
DOC_USP7_UBL2_3 | 72 | 76 | PF12436 | 0.272 |
LIG_BIR_III_2 | 114 | 118 | PF00653 | 0.429 |
LIG_EH1_1 | 56 | 64 | PF00400 | 0.212 |
LIG_eIF4E_1 | 57 | 63 | PF01652 | 0.212 |
LIG_FHA_2 | 20 | 26 | PF00498 | 0.290 |
LIG_FHA_2 | 53 | 59 | PF00498 | 0.293 |
LIG_FHA_2 | 62 | 68 | PF00498 | 0.290 |
LIG_FHA_2 | 75 | 81 | PF00498 | 0.300 |
LIG_SH2_GRB2like | 14 | 17 | PF00017 | 0.486 |
LIG_SH2_GRB2like | 50 | 53 | PF00017 | 0.261 |
LIG_SH2_SRC | 14 | 17 | PF00017 | 0.475 |
LIG_SH2_STAP1 | 57 | 61 | PF00017 | 0.297 |
LIG_SH2_STAT5 | 14 | 17 | PF00017 | 0.472 |
LIG_SH3_3 | 89 | 95 | PF00018 | 0.297 |
LIG_TRAF2_1 | 22 | 25 | PF00917 | 0.451 |
LIG_UBA3_1 | 36 | 45 | PF00899 | 0.281 |
LIG_WRC_WIRS_1 | 62 | 67 | PF05994 | 0.212 |
MOD_CK1_1 | 7 | 13 | PF00069 | 0.558 |
MOD_CK2_1 | 19 | 25 | PF00069 | 0.189 |
MOD_CK2_1 | 52 | 58 | PF00069 | 0.317 |
MOD_CK2_1 | 61 | 67 | PF00069 | 0.343 |
MOD_CK2_1 | 74 | 80 | PF00069 | 0.327 |
MOD_GSK3_1 | 3 | 10 | PF00069 | 0.497 |
MOD_N-GLC_1 | 51 | 56 | PF02516 | 0.346 |
MOD_N-GLC_1 | 8 | 13 | PF02516 | 0.664 |
MOD_NEK2_1 | 74 | 79 | PF00069 | 0.322 |
MOD_NMyristoyl | 1 | 7 | PF02799 | 0.582 |
MOD_PIKK_1 | 52 | 58 | PF00454 | 0.423 |
MOD_Plk_1 | 52 | 58 | PF00069 | 0.381 |
MOD_Plk_1 | 7 | 13 | PF00069 | 0.602 |
MOD_Plk_4 | 10 | 16 | PF00069 | 0.434 |
MOD_Plk_4 | 87 | 93 | PF00069 | 0.320 |
MOD_SPalmitoyl_4 | 1 | 7 | PF01529 | 0.530 |
MOD_SUMO_rev_2 | 67 | 74 | PF00179 | 0.337 |
TRG_DiLeu_BaEn_1 | 58 | 63 | PF01217 | 0.212 |
TRG_DiLeu_BaEn_2 | 96 | 102 | PF01217 | 0.342 |
TRG_ER_diArg_1 | 122 | 125 | PF00400 | 0.407 |
TRG_NLS_MonoCore_2 | 42 | 47 | PF00514 | 0.382 |
TRG_NLS_MonoExtN_4 | 43 | 48 | PF00514 | 0.374 |
Protein | Taxonomy | Sequence identity | Coverage |
---|---|---|---|
A0A0N0P6Y3 | Leptomonas seymouri | 88% | 99% |
A0A0N0P7C3 | Leptomonas seymouri | 36% | 90% |
A0A0N1HYV4 | Leptomonas seymouri | 61% | 100% |
A0A0N1I5S6 | Leptomonas seymouri | 44% | 85% |
A0A0N1I8U4 | Leptomonas seymouri | 33% | 97% |
A0A0N1P9P7 | Leptomonas seymouri | 39% | 67% |
A0A0N1PCZ0 | Leptomonas seymouri | 46% | 100% |
A0A0N1PE11 | Leptomonas seymouri | 38% | 92% |
A0A1X0NNW3 | Trypanosomatidae | 50% | 100% |
A0A1X0NW79 | Trypanosomatidae | 44% | 66% |
A0A1X0NW95 | Trypanosomatidae | 79% | 100% |
A0A1X0NWH2 | Trypanosomatidae | 35% | 94% |
A0A1X0NWV3 | Trypanosomatidae | 78% | 88% |
A0A1X0NXS9 | Trypanosomatidae | 36% | 96% |
A0A1X0NXT9 | Trypanosomatidae | 39% | 100% |
A0A1X0NYV3 | Trypanosomatidae | 41% | 95% |
A0A3Q8I9V9 | Leishmania donovani | 46% | 100% |
A0A3Q8IBM6 | Leishmania donovani | 35% | 98% |
A0A3Q8IBP3 | Leishmania donovani | 39% | 90% |
A0A3Q8IDP8 | Leishmania donovani | 46% | 87% |
A0A3Q8IKN9 | Leishmania donovani | 99% | 100% |
A0A3R7MB04 | Trypanosoma rangeli | 46% | 100% |
A0A3R7MWC6 | Trypanosoma rangeli | 74% | 98% |
A0A3S7WW23 | Leishmania donovani | 56% | 96% |
A0A3S7WZ86 | Leishmania donovani | 40% | 92% |
A0A422MSY8 | Trypanosoma rangeli | 73% | 78% |
A0A422MSZ3 | Trypanosoma rangeli | 74% | 100% |
A0A422MUY0 | Trypanosoma rangeli | 43% | 87% |
A0A422N035 | Trypanosoma rangeli | 37% | 94% |
A0A422N058 | Trypanosoma rangeli | 42% | 86% |
A4H7N9 | Leishmania braziliensis | 45% | 100% |
A4H7P0 | Leishmania braziliensis | 45% | 100% |
A4HEG7 | Leishmania braziliensis | 39% | 100% |
A4HW29 | Leishmania infantum | 46% | 100% |
A4HYW5 | Leishmania infantum | 39% | 100% |
A4HYW6 | Leishmania infantum | 35% | 95% |
A4HYX1 | Leishmania infantum | 42% | 100% |
A4HYX3 | Leishmania infantum | 56% | 100% |
A4I1M3 | Leishmania infantum | 40% | 92% |
C9ZIF2 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 40% | 100% |
C9ZIF5 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 61% | 100% |
C9ZIF6 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 63% | 100% |
E8NHG3 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 34% | 78% |
E9AIH7 | Leishmania braziliensis | 36% | 100% |
E9AIH8 | Leishmania braziliensis | 34% | 95% |
E9AII3 | Leishmania braziliensis | 44% | 100% |
E9AII5 | Leishmania braziliensis | 60% | 100% |
E9AII6 | Leishmania braziliensis | 96% | 100% |
E9APT0 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 46% | 100% |
E9AUR2 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 37% | 100% |
E9AUR3 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 36% | 95% |
E9AUR8 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 44% | 100% |
E9AUS0 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 57% | 100% |
E9AUS1 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 95% | 100% |
E9AXQ7 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 39% | 100% |
P84150 | Leishmania major | 35% | 95% |
Q4Q9R4 | Leishmania major | 39% | 100% |
Q4QCS4 | Leishmania major | 38% | 100% |
Q4QFP8 | Leishmania major | 46% | 100% |
Q5SDH3 | Leishmania major | 41% | 100% |
Q5SDH4 | Leishmania major | 58% | 100% |
Q5SDH5 | Leishmania major | 97% | 100% |